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1

Arthropod Alkaloids in Poison Frogs: A Review of the ‘Dietary Hypothesis’

A. Saporito, Ralph, F. Spande, Thomas, Martin Garraffo, H., A. Donnelly, Maureen

Journal:

Year:

2009

Language:

english

File:

PDF, 2.43 MB

english, 2009

2

An uptake system for dietary alkaloids in poison frogs (Dendrobatidae)

John W. Daly, Sherrie I. Secunda, H.Martin Garraffo, Thomas F. Spande, Anthony Wisnieski, Jack F. Cover Jr

Journal:

Year:

1994

Language:

english

File:

PDF, 489 KB

english, 1994

3

Spatial and temporal patterns of alkaloid variation in the poison frog Oophaga pumilio in Costa Rica and Panama over 30 years

Ralph A. Saporito, Maureen A. Donnelly, Poonam Jain, H. Martin Garraffo, Thomas F. Spande, John W. Daly

Journal:

Year:

2007

Language:

english

File:

PDF, 1.09 MB

english, 2007

4

Ammonia chemical ionization tandem mass spectrometry in structure determination of alkaloids. I. Pyrrolidines, piperidines, decahydroquinolines, pyrrolizidines, indolizidines, quinolizidines and an azabicyclo[5.3.0]decane

H. Martin Garraffo, Thomas F. Spande, Tappey H. Jones, John W. Daly

Journal:

Rapid Communications in Mass Spectrometry

Year:

1999

Language:

english

File:

PDF, 157 KB

english, 1999

5

ChemInform Abstract: The Isolation and Structure of the Novel cis-Fused Indolizidine 249H from Frog Skin: cis- vs. trans-Fused Indolizidines Distinguished by NMR.

Takashi Tokuyama, Atsushi Shimada, H. Martin Garraffo, Thomas F. Spande, John W. Daly

Journal:

Year:

1999

File:

PDF, 26 KB

1999

6

ChemInform Abstract: The Isolation and Structure of Pumiliotoxin 341A: A Novel Cyclic Ether from the Frog Epipedobates tricolor.

Poonam Jain, Thomas F. Spande, H. Martin Garraffo, John W. Daly

Journal:

Year:

1999

File:

PDF, 26 KB

1999

7

ChemInform Abstract: Alkaloids from Amphibian Skins

John W. Daly, H. Martin Garraffo, Thomas F. Spande

Journal:

Year:

2000

File:

PDF, 25 KB

2000

8

Synthesis of Alkaloid 223A and a Structural Revision.

Naoki Toyooka, Ayako Fukutome, Hideo Nemoto, John W. Daly, Thomas F. Spande, H. Martin Garraffo, Tetsuo Kaneko

Journal:

Year:

2002

File:

PDF, 25 KB

2002

9

A Structure for 261C, a Novel Tricyclic Alkaloid from the Madagascan Poison Frog, Mantella betsileo.

Tetsuo Kaneko, Thomas F. Spande, H. Martin Garraffo, Herman J. C. Yeh, John W. Daly, Nirina R. Andriamaharavo, Marta Andriantsiferana

Journal:

Year:

2003

File:

PDF, 59 KB

2003

10

Enantioselective Synthesis of Poison-Frog Alkaloid 237D (I) and Determination of Absolute Stereochemistry.

Naoki Toyooka, Masashi Kawasaki, Hideo Nemoto, John W. Daly, Thomas F. Spande, H. Martin Garraffo

Journal:

Year:

2005

File:

PDF, 9 KB

2005

11

Enantioselective Syntheses of Two Diastereomers of 223V, an Alkaloid from the Poison Frog Dendrobates pumilio.

Naoki Toyooka, Hideo Nemoto, Masashi Kawasaki, H. Martin Garraffo, Thomas F. Spande, Jahn W. Daly

Journal:

Year:

2005

File:

PDF, 11 KB

2005

12

ChemInform Abstract: Discovery of Batrachotoxin: The Launch of the Frog Alkaloid Program at NIH

H. Martin Garraffo, Thomas F. Spande

Journal:

Year:

2009

File:

PDF, 11 KB

2009

13

ChemInform Abstract: Arthropod Alkaloids in Poison Frogs: A Review of the “Dietary Hypothesis”.

Ralph A. Saporita, Thomas F. Spande, H. Martin Garraffo, Maureen A. Donnelly

Journal:

Year:

2009

File:

PDF, 11 KB

2009

14

ChemInform Abstract: Epibatidine: From Frog Alkaloid to Analgesic Clinical Candidates. A Testimonial to “True Grit”!

H. Martin Garraffo, Thomas F. Spande, Michael Williams

Journal:

Year:

2009

File:

PDF, 11 KB

2009

15

ChemInform Abstract: Dioicine: A Novel Prenylated Purine Alkaloid from Gymnocladus dioicus

Richard W. Fitch, Thomas F. Spande, H. Martin Garraffo, Rachael R. Chase, Mylaka A. Clinedinst, Derek A. Parkes, Richard Reed, Neol F. Whittaker, John W. Daly

Journal:

Year:

2009

File:

PDF, 17 KB

2009

16

Synthesis of poison-frog alkaloids 233A, 235U, and 251AA and their inhibitory effects on neuronal nicotinic acetylcholine receptors

Naoki Toyooka, Soushi Kobayashi, Dejun Zhou, Hiroshi Tsuneki, Tsutomu Wada, Hideki Sakai, Hideo Nemoto, Toshiyasu Sasaoka, H. Martin Garraffo, Thomas F. Spande, John W. Daly

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 239 KB

english, 2007

17

Enantioselective syntheses of two 5, 9E diastereomers of 223V, an alkaloid from the poison frog Dendrobates pumilio

Naoki Toyooka, Hideo Nemoto, Masashi Kawasaki, H. Martin Garraffo, Thomas F. Spande, John W. Daly

Journal:

Year:

2005

Language:

english

File:

PDF, 318 KB

english, 2005

18

Corrigendum to “Enantioselective syntheses of two 5, 9E diastereomers of 223V, an alkaloid from the poison frog Dendrobates pumilio” [Tetrahedron 61 (2005) 1187]

Naoki Toyooka, Hideo Nemoto, Masashi Kawasaki, H. Martin Garraffo, Thomas F. Spande, John W. Daly

Journal:

Year:

2005

Language:

english

File:

PDF, 52 KB

english, 2005

19

The enantioselective synthesis of poison-frog alkaloids (−)-203A, (−)-209B, (−)-231C, (−)-233D, and (−)-235B″

Naoki Toyooka, Zhou Dejun, Hideo Nemoto, H. Martin Garraffo, Thomas F. Spande, John W. Daly

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 119 KB

english, 2006

20

Enantioselective syntheses of poison-frog alkaloids: 219F and 221I and an epimer of 193E

Naoki Toyooka, Zhou Dejun, Hideo Nemoto, H. Martin Garraffo, Thomas F. Spande, John W. Daly

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 89 KB

english, 2006

21

Cis- and trans-configurations of α,α′-disubstituted piperidines and pyrrolidines by GC-FTIR; application to decahydroquinoline stereochemistry

H. Martin Garraffo, Lara D. Simon, John W. Daly, Thomas F. Spande, Tappey H. Jones

Journal:

Year:

1994

Language:

english

File:

PDF, 713 KB

english, 1994

22

Ammonia chemical ionization tandem mass spectrometry in structural determination of alkaloids. II. Tetraponerines from pseudomyrmecine ants

H. Martin Garraffo, Thomas F. Spande, Poonam Jain, Tetsuo Kaneko, Tappey H. Jones, Murray S. Blum, T. M. Musthak Ali, Roy R. Snelling, Lynne A. Isbell, Hamish G. Robertson, John W. Daly

Journal:

Rapid Communications in Mass Spectrometry

Year:

2001

Language:

english

File:

PDF, 161 KB

english, 2001

23

Dietary source for skin alkaloids of poison frogs (Dendrobatidae)?

John W. Daly, H. Martin Garraffo, Thomas F. Spande, César Jaramillo, A. Stanley Rand

Journal:

Journal of Chemical Ecology

Year:

1994

Language:

english

File:

PDF, 614 KB

english, 1994

24

John William Daly, 1933–2008

H. Martin Garraffo

Journal:

Cellular and Molecular Neurobiology

Year:

2009

Language:

english

File:

PDF, 109 KB

english, 2009

25

Geographic and Seasonal Variation in Alkaloid-Based Chemical Defenses ofDendrobates pumiliofrom Bocas del Toro, Panama

Ralph A. Saporito, Maureen A. Donnelly, H. Martin Garraffo, Thomas F. Spande, John W. Daly

Journal:

Journal of Chemical Ecology

Year:

2006

Language:

english

File:

PDF, 457 KB

english, 2006

26

Individual and Geographic Variation of Skin Alkaloids in Three Species of Madagascan Poison Frogs (Mantella)

John W. Daly, H. Martin Garraffo, Thomas F. Spande, Lesley-Ann Giddings, Ralph A. Saporito, David R. Vieites, Miguel Vences

Journal:

Journal of Chemical Ecology

Year:

2008

Language:

english

File:

PDF, 465 KB

english, 2008

27

Alkaloids in the MiteScheloribates laevigatus: Further Alkaloids Common to Oribatid Mites and Poison Frogs

Ralph A. Saporito, Roy A. Norton, Nirina R. Andriamaharavo, Hugo Martin Garraffo, Thomas F. Spande

Journal:

Journal of Chemical Ecology

Year:

2011

Language:

english

File:

PDF, 216 KB

english, 2011

28

Highly stereoselective construction of trans(2,3)-cis(2,6)-trisubstituted piperidines: An application to the chiral synthesis of Dendrobates alkaloids

Naoki Toyooka, Keiko Tanaka, Takefumi Momose, John W Daly, H.Martin Garraffo

Journal:

Year:

1997

Language:

english

File:

PDF, 1.30 MB

english, 1997

29

Involvement of PDK1, PKC and TOR signalling pathways in basal fluconazole tolerance in Cryptococcus neoformans

Hyeseung Lee, Ami Khanal Lamichhane, H. Martin Garraffo, Kyung J. Kwon-Chung, Yun C. Chang

Journal:

Molecular Microbiology

Year:

2012

Language:

english

File:

PDF, 899 KB

english, 2012

30

Arthropod–Frog Connection: Decahydroquinoline and Pyrrolizidine Alkaloids Common to Microsympatric Myrmicine Ants and Dendrobatid Frogs

John W. Daly, H. Martin Garraffo, Poonam Jain, Thomas F. Spande, Roy R. Snelling, César Jaramillo, A. Stanley Rand

Journal:

Journal of Chemical Ecology

Year:

2000

Language:

english

File:

PDF, 126 KB

english, 2000

31

Further Alkaloids Common to Ants and Frogs: Decahydroquinolines and a Quinolizidine

Tappey H. Jones, Jeffrey S. T. Gorman, Roy R. Snelling, Jacques H. C. Delabie, Murray S. Blum, H. Martin Garraffo, Poonam Jain, John W. Daly, Thomas F. Spande

Journal:

Journal of Chemical Ecology

Year:

1999

Language:

english

File:

PDF, 693 KB

english, 1999

32

Fluconazole therapy for Candida albicans urinary tract infections in infants

Triolo, Val&#x000E9, rie, Gari-Toussaint, Martine, Casagrande, Florence, Garraffo, Rodolphe, Dageville, Christian, Boutt&#x000E9, , Patrick, B&#x000E9, rard, Etienne

Journal:

Pediatric Nephrology

Year:

2002

Language:

english

File:

PDF, 41 KB

english, 2002

33

A review of chemical ecology in poison frogs

Ralph A. Saporito, Maureen A. Donnelly, Thomas F. Spande, H. Martin Garraffo

Journal:

Year:

2012

Language:

english

File:

PDF, 302 KB

english, 2012

34

Variability in alkaloid profiles in neotropical poison frogs (Dendrobatidae): Genetic versus environmental determinants

John W. Daly, Sherrie I. Secunda, H.Martin Garraffo, Thomas F. Spande, Anthony Wisnieski, Charles Nishihira, John F. Cover Jr

Journal:

Year:

1992

Language:

english

File:

PDF, 649 KB

english, 1992

35

Biologically active substances from amphibians: preliminary studies on anurans from twenty-one genera of Thailand

John W. Daly, Naratitt Noimai, Boonsong Kongkathip, Ngampong Kongkathip, Jason M. Wilham, H. Martin Garraffo, Tetsuo Kaneko, Thomas F. Spande, Yuth Nimit, Jarujin Nabhitabhata, Tanya Chan-Ard

Journal:

Year:

2004

Language:

english

File:

PDF, 259 KB

english, 2004

36

Indolizidine 239Q and quinolizidine 275I. Major alkaloids in two Argentinian bufonid toads (Melanophryniscus)

John W. Daly, H. Martin Garraffo, Thomas F. Spande, Herman J.C. Yeh, Paola M. Peltzer, Pedro M. Cacivio, J. Diego Baldo, Julián Faivovich

Journal:

Year:

2008

Language:

english

File:

PDF, 466 KB

english, 2008

37

Absence of skin alkaloids in captive-raised Madagascan mantelline frogs (Mantella) and sequestration of dietary alkaloids

John W. Daly, H. Martin Garraffo, Geoffrey S.E. Hall, John F. Cover Jr

Journal:

Year:

1997

Language:

english

File:

PDF, 355 KB

english, 1997

38

Structure of Alkaloid 275A, a Novel 1-Azabicyclo[5.3.0]decane from a Dendrobatid Frog, Dendrobates l ehmanni : Synthesis of the Tetrahydrodiastereomers

Garraffo, H. Martin, Jain, Poonam, Spande, Thomas F., Daly, John W., Jones, Tappey. H., Smith, Lance J., Zottig, Victor E.

Journal:

Journal of Natural Products

Year:

2001

Language:

english

File:

PDF, 103 KB

english, 2001

39

Pseudophrynaminol: A potent noncompetitive blocker of nicotinic receptor-channels

Barbara Badio, H.Martin Garraffo, William L. Padgett, Nigel H. Greig, John W. Daly

Journal:

Biochemical Pharmacology

Year:

1997

Language:

english

File:

PDF, 679 KB

english, 1997

40

Synthesis and nicotinic activity of epiboxidine: an isoxazole analogue of epibatidine

Barbara Badio, H.Martin Garraffo, Carlton V Plummer, William L Padgett, John W Daly

Journal:

European Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 199 KB

english, 1997

41

Venom Chemistry of the Ant Myrmicaria melanogaster from Brunei

Jones, Tappey H., Voegtle, Heather L., Miras, Heather M., Weatherford, Robert G., Spande, Thomas F., Garraffo, H. Martin, Daly, John W., Davidson, Diane W., Snelling, Roy R.

Journal:

Journal of Natural Products

Year:

2007

Language:

english

File:

PDF, 179 KB

english, 2007

42

Dioicine: A Novel Prenylated Purine Alkaloid from Gymnocladus dioicus

W. Fitch, Richard, R. Chase, Rachael, F. Spande, Thomas, Martin Garraffo, H., W. Daly, John, A. Parkes, Derek, Reed, Richard, A. Clinedinst, Mylaka, F. Whittaker, Noel

Journal:

Year:

2009

Language:

english

File:

PDF, 108 KB

english, 2009

43

N -Methyldecahydroquinolines: An Unexpected Class of Alkaloids from Amazonian Poison Frogs (Dendrobatidae)

Daly, John W., Ware, Nathaniel, Saporito, Ralph A., Spande, Thomas F., Garraffo, H. Martin

Journal:

Journal of Natural Products

Year:

2009

Language:

english

File:

PDF, 155 KB

english, 2009

44

Sex-Related Differences in Alkaloid Chemical Defenses of the Dendrobatid Frog Oophaga pumilio from Cayo Nancy, Bocas del Toro, Panama ⊥

Saporito, Ralph A., Donnelly, Maureen A., Madden, Anne A., Garraffo, H. Martin, Spande, Thomas F.

Journal:

Journal of Natural Products

Year:

2010

Language:

english

File:

PDF, 243 KB

english, 2010

45

Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity from an Ecuadoran poison frog

Spande, Thomas F., Garraffo, Hugo Martin, Edwards, Michael W., Yeh, Herman J. C., Pannell, Lewis, Daly, John W.

Journal:

Journal of the American Chemical Society

Year:

1992

Language:

english

File:

PDF, 520 KB

english, 1992

46

Alkaloids from Amphibian Skin: A Tabulation of Over Eight-Hundred Compounds

Daly, John W., Spande, Thomas F., Garraffo, H. Martin

Journal:

Journal of Natural Products

Year:

2005

Language:

english

File:

PDF, 648 KB

english, 2005

47

Synthesis of Alkaloid 223A and a Structural Revision

Toyooka, Naoki, Fukutome, Ayako, Nemoto, Hideo, Daly, John W., Spande, Thomas F., Garraffo, H. Martin, Kaneko, Tetsuo

Journal:

Organic Letters

Year:

2002

Language:

english

File:

PDF, 63 KB

english, 2002

48

Alkaloids from single skins of the Argentinian toadMelanophryniscus rubriventris(ANURA, BUFONIDAE): An unexpected variability in alkaloid profiles and a profusion of new structures

Garraffo, H Martin, Andriamaharavo, Nirina R, Vaira, Marcos, Quiroga, MarÃa F, Heit, Cecilia, Spande, Thomas F

Journal:

Year:

2012

Language:

english

File:

PDF, 2.00 MB

english, 2012

49

Occurrence and Significance of Decahydroquinolines from Dendrobatid Poison Frogs and a Myrmicine Ant: Use of 1 H and 13 C NMR in Their Conformational Analysis †

Spande, Thomas F., Jain, Poonam, Garraffo, H. Martin, Pannell, Lewis K., Yeh, Herman J. C., Daly, John W., Fukumoto, Sinji, Imamura, Kohji, Tokuyama, Takashi, Torres, Juan A., Snelling, Roy R., Jones,

Journal:

Journal of Natural Products

Year:

1999

Language:

english

File:

PDF, 348 KB

english, 1999

50

A 1,4-Disubstituted Quinolizidine from a Madagascan Mantelline Frog ( Mantella)

Jain, Poonam, Garraffo, H. Martin, Yeh, Herman J. C., Spande, Thomas F., Daly, John W., Andriamaharavo, N. R., Andriantsiferana, M.

Journal:

Journal of Natural Products

Year:

1996

Language:

english

File:

PDF, 129 KB

english, 1996

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