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51

Experimental Resolution of Cooperative Free Energies for the Ten Ligation States of Human Hemoglobin

Francine R. Smith and Gary K. Ackers

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 1.18 MB

english, 1985

52

``Footprint'' Titrations Yield Valid Thermodynamic Isotherms

Michael Brenowitz, Donald F. Senear, Madeline A. Shea and Gary K. Ackers

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.20 MB

english, 1986

53

Three-State Combinatorial Switching in Hemoglobin Tetramers: Comparison between Functional Energetics and Molecular Structures

Francine R. Smith, David Gingrich, Brian M. Hoffman and Gary K. Ackers

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 845 KB

english, 1987

54

Heterometallic Hybrids of Homometallic Human Hemoglobins

Yingwen Huang, Takashi Yonetani, Antonio Tsuneshige, Brain M. Hoffman and Gary K. Ackers

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.15 MB

english, 1996

55

The Linkage between Oxygenation and Subunit Dissociation in Human Hemoglobin

Gary K. Ackers and Herbert R. Halvorson

Journal:

Proceedings of the National Academy of Sciences

Year:

1974

Language:

english

File:

PDF, 796 KB

english, 1974

56

Self-Association of Hemoglobin βSHChains is Linked to Oxygenation

Roland Valdes and Gary K. Ackers

Journal:

Proceedings of the National Academy of Sciences

Year:

1978

Language:

english

File:

PDF, 760 KB

english, 1978

57

Reciprocal Effects in Human Hemoglobin: Direct Measurement of the Dimer-Tetramer Association Constant at Partial Oxygen Saturation

Roland Valdes, Leland P. Vickers, Herbert R. Halvorson and Gary K. Ackers

Journal:

Proceedings of the National Academy of Sciences

Year:

1978

Language:

english

File:

PDF, 780 KB

english, 1978

58

Quaternary Enhancement in Binding of Oxygen by Human Hemoglobin

Frederick C. Mills and Gary K. Ackers

Journal:

Proceedings of the National Academy of Sciences

Year:

1979

Language:

english

File:

PDF, 1.30 MB

english, 1979

59

Functional properties of human hemoglobins synthesized from recombinant mutant .beta.-globins

Doyle, Michael L., Lew, George, De Young, Alice, Kwiatkowski, Laura, Wierzba, Anita, Noble, Robert W., Ackers, Gary K.

Journal:

Year:

1992

Language:

english

File:

PDF, 1.31 MB

english, 1992

60

Cooperative protein-DNA interactions: effects of potassium chloride on .lambda. cI binding to OR

Koblan, Kenneth S., Ackers, Gary K.

Journal:

Year:

1991

Language:

english

File:

PDF, 761 KB

english, 1991

61

Bohr Effects of the Partially-Ligated (CN-met) Intermediates of Hemoglobin as Probed by Quaternary Assembly

Daugherty, Margaret A., Shea, Madeline A., Ackers, Gary K.

Journal:

Year:

1994

Language:

english

File:

PDF, 1.49 MB

english, 1994

62

Effects of inositol hexasulfate on the oxygen affinity of hemoglobin: verification of the integral function theory of thermodynamic linkage

Ackers, Gary K., Benesch, Ruth E., Edalji, Rohinton

Journal:

Year:

1982

Language:

english

File:

PDF, 605 KB

english, 1982

63

Effects of ionic strength and state of assembly on kinetics of hydrogen exchange of calf thymus histones

McCarthy, Michael P., Steffen, Pamela K., Allewell, Norma M., Benedict, Robert C., Moudrianakis, Evangelos N., Ackers, Gary K.

Journal:

Year:

1984

Language:

english

File:

PDF, 461 KB

english, 1984

64

Long-Range, Small Magnitude Nonadditivity of Mutational Effects in Proteins

LiCata, Vince J., Ackers, Gary K.

Journal:

Year:

1995

Language:

english

File:

PDF, 1.44 MB

english, 1995

65

Kinetics of deoxyhemoglobin subunit dissociation determined by haptoglobin binding: estimation of the equilibrium constant from forward and reverse rates

Ip, Stephen H. C., Johnson, Michael L., Ackers, Gary K.

Journal:

Year:

1976

Language:

english

File:

PDF, 823 KB

english, 1976

66

Electrostatic contributions to the energetics of dimer-tetramer assembly in human hemoglobin: pH dependence and effect of specifically bound chloride ions

Flanagan, Margaret A., Ackers, Gary K., Matthew, James B., Hanania, George I. H., Gurd, Frank R. N.

Journal:

Year:

1981

Language:

english

File:

PDF, 1.44 MB

english, 1981

67

Single-Site Mutations in the C-Terminal Domain of Bacteriophage .lambda. cI Repressor Alter Cooperative Interactions between Dimers Adjacently Bound to OR

Burz, David S., Ackers, Gary K.

Journal:

Year:

1994

Language:

english

File:

PDF, 2.91 MB

english, 1994

68

Molecular Exclusion and Restricted Diffusion Processes in Molecular-Sieve Chromatography *

Ackers, Gary K.

Journal:

Year:

1964

Language:

english

File:

PDF, 1000 KB

english, 1964

69

Thermodynamic Studies on the Equilibrium Properties of a Series of Recombinant βW37 Hemoglobin Mutants †

Kiger, Laurent, Klinger, Alexandra L., Kwiatkowski, Laura D., De Young, Alice, Doyle, Michael L., Holt, Jo M., Noble, Robert W., Ackers, Gary K.

Journal:

Year:

1998

Language:

english

File:

PDF, 114 KB

english, 1998

70

Linked functions in allosteric proteins: an exact theory for the effect of organic phosphates on oxygen affinity of hemoglobin

Ackers, Gary K.

Journal:

Year:

1979

Language:

english

File:

PDF, 1.07 MB

english, 1979

71

Proton-linked contributions to site-specific interactions of .lambda. cI repressor and OR

Senear, Donald F., Ackers, Gary K.

Journal:

Year:

1990

Language:

english

File:

PDF, 1.82 MB

english, 1990

72

Asymmetric Distribution of Cooperativity in the Binding Cascade of Normal Human Hemoglobin. 2. Stepwise Cooperative Free Energy †

Holt, Jo M., Ackers, Gary K.

Journal:

Year:

2005

Language:

english

File:

PDF, 2.94 MB

english, 2005

73

Experimental resolution of cooperative free energies for the ten ligation species of cobalt(II)/iron(II)-carbon monoxide hemoglobin

Speros, Philip C., LiCata, Vince J., Yonetani, Takashi, Ackers, Gary K.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.08 MB

english, 1991

74

Enthalpic and Entropic Components of Cooperativity for the Partially Ligated Intermediates of Hemoglobin Support a "Symmetry Rule" Mechanism

Huang, Yingwen, Ackers, Gary K.

Journal:

Year:

1995

Language:

english

File:

PDF, 1.94 MB

english, 1995

75

Isolation of .lambda. repressor mutants with defects in cooperative operator binding

Beckett, Dorothy, Burz, David S., Ackers, Gary K., Sauer, Robert T.

Journal:

Year:

1993

Language:

english

File:

PDF, 908 KB

english, 1993

76

Oxygenation-linked subunit interactions in human hemoglobin: experimental studies on the concentration dependence of oxygenation curves

Mills, Frederick C., Johnson, Michael L., Ackers, Gary K.

Journal:

Year:

1976

Language:

english

File:

PDF, 1.43 MB

english, 1976

77

Calorimetric Analysis of .lambda. cI Repressor Binding to DNA Operator Sites

Merabet, Eddine, Ackers, Gary K.

Journal:

Year:

1995

Language:

english

File:

PDF, 3.17 MB

english, 1995

78

The Molecular Code for Hemoglobin Allostery Revealed by Linking the Thermodynamics and Kinetics of Quaternary Structural Change. 2. Cooperative Free Energies of (α FeCO β Fe ) 2 and (α Fe β FeCO ) 2 T-State Tetramers †

Goldbeck, Robert A., Esquerra, Raymond M., Kliger, David S., Holt, Jo M., Ackers, Gary K.

Journal:

Year:

2004

Language:

english

File:

PDF, 432 KB

english, 2004

79

Oxygenation-linked subunit interactions in human hemoglobin: analysis of linkage functions for constituent energy terms

Johnson, Michael L., Halvorson, Herbert R., Ackers, Gary K.

Journal:

Year:

1976

Language:

english

File:

PDF, 890 KB

english, 1976

80

Calorimetric determination of the heat of oxygenation of human hemoglobin as a function of pH and the extent of reaction

Atha, Donald H., Ackers, Gary K.

Journal:

Year:

1974

Language:

english

File:

PDF, 789 KB

english, 1974

81

Effects of protons on the oxygenation-linked subunit assembly in human hemoglobin

Chu, Amy H., Turner, Benjamin W., Ackers, Gary K.

Journal:

Year:

1984

Language:

english

File:

PDF, 1.74 MB

english, 1984

82

Energetics of subunit dimerization in bacteriophage .lambda. cI repressor: linkage to protons, temperature, and KCl

Koblan, Kenneth S., Ackers, Gary K.

Journal:

Year:

1991

Language:

english

File:

PDF, 571 KB

english, 1991

83

Thermodynamic analysis of human hemoglobins in terms of the Perutz mechanism: extensions of the Szabo Karplus model to include subunit assembly

Johnson, Michael L., Ackers, Gary K.

Journal:

Year:

1982

Language:

english

File:

PDF, 1.39 MB

english, 1982

84

Thermodynamic Stability of the Asymmetric Doubly-Ligated Hemoglobin Tetramer (α +CN β +CN )(αβ): Methodological and Mechanistic Issues †

Ackers, Gary K., Perrella, Michele, Holt, Jo M., Denisov, Ilya, Huang, Yingwen

Journal:

Year:

1997

Language:

english

File:

PDF, 289 KB

english, 1997

85

Measurement of DNA-protein equilibria using gel chromatography: application to the HinfI restriction endonuclease

Frankel, Alan D., Ackers, Gary K., Smith, Hamilton O.

Journal:

Year:

1985

Language:

english

File:

PDF, 735 KB

english, 1985

86

Self-association and DNA binding of .lambda. cI repressor N-terminal domains reveal linkage between sequence-specific binding and the C-terminal cooperativity domain

Bain, David L., Ackers, Gary K.

Journal:

Year:

1994

Language:

english

File:

PDF, 2.37 MB

english, 1994

87

Asymmetric Distribution of Cooperativity in the Binding Cascade of Normal Human Hemoglobin. 1. Cooperative and Noncooperative Oxygen Binding in Zn-Substituted Hemoglobin †

Holt, Jo M., Klinger, Alexandra L., Yarian, Connie S., Keelara, Varsha, Ackers, Gary K.

Journal:

Year:

2005

Language:

english

File:

PDF, 3.02 MB

english, 2005

88

Linkage between cooperative oxygenation and subunit assembly of cobaltous human hemoglobin

Doyle, Michael L., Speros, Phil C., LiCata, Vince J., Gingrich, David, Hoffman, Brian M., Ackers, Gary K.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.09 MB

english, 1991

89

Molecular sieve studies of interacting protein systems. V. Association of subunits of D-amino acid oxidase apoenzyme

Henn, Suella W., Ackers, Gary K.

Journal:

Year:

1969

Language:

english

File:

PDF, 1021 KB

english, 1969

90

Linkage between oxygenation and subunit dissociation in human hemoglobin. Consequences for the analysis of oxygenation curves

Ackers, Gary K., Johnson, Michael L., Mills, Frederick C., Halvorson, Herbert R., Shapiro, Solomon

Journal:

Year:

1975

Language:

english

File:

PDF, 790 KB

english, 1975

91

Structural and Functional Properties of Human Hemoglobins Reassembled after Synthesis in Escherichia coli †,‡

Hui, Hilda L., Kavanaugh, Jeffrey S., Doyle, Michael L., Wierzba, Anita, Rogers, Paul H., Arnone, Arthur, Holt, Jo M., Ackers, Gary K., Noble, Robert W.

Journal:

Year:

1999

Language:

english

File:

PDF, 162 KB

english, 1999

92

Coupled Energetics of λ cro Repressor Self-Assembly and Site-Specific DNA Operator Binding I: Analysis of cro Dimerization from Nanomolar to Micromolar Concentrations †

Darling, Paul J., Holt, Jo M., Ackers, Gary K.

Journal:

Year:

2000

Language:

english

File:

PDF, 80 KB

english, 2000

93

Cooperative oxygen binding, subunit assembly, and sulfhydryl reaction kinetics of the eight cyanomet intermediate ligation states of human hemoglobin

Doyle, Michael L., Ackers, Gary K.

Journal:

Year:

1992

Language:

english

File:

PDF, 1.82 MB

english, 1992

94

Site-specific enthalpic regulation of DNA transcription at bacteriophage .lambda. OR

Koblan, Kenneth S., Ackers, Gary K.

Journal:

Year:

1992

Language:

english

File:

PDF, 1.73 MB

english, 1992

95

Cooperativity Mutants of Bacteriophage λ cI Repressor: Temperature Dependence of Self-Assembly †

Burz, David S., Ackers, Gary K.

Journal:

Year:

1996

Language:

english

File:

PDF, 670 KB

english, 1996

96

Interactions of the nucleosomal core histones: a calorimetric study of octamer assembly

Benedict, Robert C., Moudrianakis, Evangelos N., Ackers, Gary K.

Journal:

Year:

1984

Language:

english

File:

PDF, 647 KB

english, 1984

97

Direct and indirect pathways of functional coupling in human hemoglobin are revealed by quantitative low-temperature isoelectric focusing of mutant hybrids

LiCata, Vince J., Speros, Phil C., Rovida, Ermanna, Ackers, Gary K.

Journal:

Year:

1990

Language:

english

File:

PDF, 2.85 MB

english, 1990

98

Energetics of cooperative protein-DNA interactions: comparison between quantitative deoxyribonuclease footprint titration and filter binding

Senear, Donald F., Brenowitz, Michael, Shea, Madeline A., Ackers, Gary K.

Journal:

Year:

1986

Language:

english

File:

PDF, 2.14 MB

english, 1986

99

The Molecular Code for Hemoglobin Allostery Revealed by Linking the Thermodynamics and Kinetics of Quaternary Structural Change. 1. Microstate Linear Free Energy Relations †

Goldbeck, Robert A., Esquerra, Raymond M., Holt, Jo M., Ackers, Gary K., Kliger, David S.

Journal:

Year:

2004

Language:

english

File:

PDF, 320 KB

english, 2004

100

[Methods in Enzymology] Energetics of Biological Macromolecules, Part D Volume 379 || Analyzing Intermediate State Cooperativity in Hemoglobin

Ackers, Gary K.

Year:

2004

Language:

english

File:

PDF, 363 KB

english, 2004