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51

Novel Quinazolin-4(3 H )-one/Schiff Base Hybrids as Antiproliferative and Phosphodiesterase 4 Inhibitors: Design, Synthesis, and Docking Studies

Abdel-Rahman, Hamdy M., Abdel-Aziz, Mohamed, Canzoneri, Joshua C., Gary, Bernard D., Piazza, Gary A.

Journal:

Archiv der Pharmazie

Year:

2014

Language:

english

File:

PDF, 387 KB

english, 2014

52

Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells

Koneczny, Inga, Schulenburg, Axel, Hudec, Xenia, Knöfler, Martin, Holzmann, Klaus, Piazza, Gary, Reynolds, Robert, Valent, Peter, Marian, Brigitte

Journal:

Molecular Carcinogenesis

Year:

2014

Language:

english

File:

PDF, 361 KB

english, 2014

53

Properties of kinesin isolated from human prostatic DU 145 tumor cells and bovine brain

Stearns, Mark E., Piazza, Gary A.

Journal:

Biochemistry and Cell Biology

Year:

1990

Language:

english

File:

PDF, 682 KB

english, 1990

54

Hypoxia-regulated microRNAs in human cancer

Shen, Guomin, Li, Xiaobo, Jia, Yong-feng, Piazza, Gary A, Xi, Yaguang

Journal:

Acta Pharmacologica Sinica

Year:

2013

Language:

english

File:

PDF, 357 KB

english, 2013

55

Mechanistic Role of MicroRNA in Cancer Chemoprevention by Nonsteroidal Anti-inflammatory Drugs

Ma, Ruixia, Yi, Bin, Piazza, Gary A., Xi, Yaguang

Journal:

Current Pharmacology Reports

Year:

2015

Language:

english

File:

PDF, 543 KB

english, 2015

56

A Novel Sulindac Derivative Lacking Cyclooxygenase-Inhibitory Activities Suppresses Carcinogenesis in the Transgenic Adenocarcinoma of Mouse Prostate Model

Zhang, Y., Zhang, J., Wang, L., Quealy, E., Gary, B. D., Reynolds, R. C., Piazza, G. A., Lu, J.

Journal:

Cancer Prevention Research

Year:

2010

Language:

english

File:

PDF, 588 KB

english, 2010

57

Colon Tumor Cell Growth-Inhibitory Activity of Sulindac Sulfide and Other Nonsteroidal Anti-Inflammatory Drugs Is Associated with Phosphodiesterase 5 Inhibition

Tinsley, H. N., Gary, B. D., Thaiparambil, J., Li, N., Lu, W., Li, Y., Maxuitenko, Y. Y., Keeton, A. B., Piazza, G. A.

Journal:

Cancer Prevention Research

Year:

2010

Language:

english

File:

PDF, 676 KB

english, 2010

58

Inhibition of PDE5 by Sulindac Sulfide Selectively Induces Apoptosis and Attenuates Oncogenic Wnt/ -Catenin-Mediated Transcription in Human Breast Tumor Cells

Tinsley, H. N., Gary, B. D., Keeton, A. B., Lu, W., Li, Y., Piazza, G. A.

Journal:

Cancer Prevention Research

Year:

2011

Language:

english

File:

PDF, 1.19 MB

english, 2011

59

A Novel Sulindac Derivative That Does Not Inhibit Cyclooxygenases but Potently Inhibits Colon Tumor Cell Growth and Induces Apoptosis with Antitumor Activity

Piazza, G. A., Keeton, A. B., Tinsley, H. N., Gary, B. D., Whitt, J. D., Mathew, B., Thaiparambil, J., Coward, L., Gorman, G., Li, Y., Sani, B., Hobrath, J. V., Maxuitenko, Y. Y., Reynolds, R. C.

Journal:

Cancer Prevention Research

Year:

2009

Language:

english

File:

PDF, 489 KB

english, 2009

60

Nanodiamond Foils for H- Stripping to Support the Spallation Neutron Source (SNS) and Related Applications

Vispute, RD, Ermer, Henry K., Sinsky, Phillip, Seiser, Andrew, Shaw, Robert W., Wilson, Leslie L., Harris, Gary, Piazza, Fabrice

Journal:

MRS Proceedings

Year:

2014

Language:

english

File:

PDF, 8.31 MB

english, 2014

61

[IEEE 2015 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS) - Estoril, Portugal (2015.1.18-2015.1.22)] 2015 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS) - Application of statistical element selection to 3D integrated AlN MEMS filters for performance correction and yield enhancement

Patterson, Albert, Calayir, Enes, Fedder, Gary K., Piazza, Gianluca, Soon, Bo Woon, Singh, Navab

Year:

2015

Language:

english

File:

PDF, 951 KB

english, 2015

62

Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/ -Catenin Signaling

Li, N., Xi, Y., Tinsley, H. N., Gurpinar, E., Gary, B. D., Zhu, B., Li, Y., Chen, X., Keeton, A. B., Abadi, A. H., Moyer, M. P., Grizzle, W. E., Chang, W.-C., Clapper, M. L., Piazza, G. A.

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 1.96 MB

english, 2013

63

Synthesis, Molecular Modeling, and Biological Evaluation of Novel Tetrahydro- β -Carboline Hydantoin and Tetrahydro- β -Carboline Thiohydantoin Derivatives as Phosphodiesterase 5 Inhibitors

Abadi, Ashraf H., Lehmann, Jochen, Piazza, Gary A., Abdel-Halim, Mohammad, Ali, Mohamed S. M.

Journal:

International Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 494 KB

english, 2011

64

COX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs

Gurpinar, Evrim, Grizzle, William E., Piazza, Gary A.

Journal:

Frontiers in Oncology

Year:

2013

Language:

english

File:

PDF, 781 KB

english, 2013

65

The Role of Cyclic Nucleotide Signaling Pathways in Cancer: Targets for Prevention and Treatment

Fajardo, Alexandra, Piazza, Gary, Tinsley, Heather

Journal:

Year:

2014

Language:

english

File:

PDF, 495 KB

english, 2014

66

[IEEE 2015 IEEE MTT-S International Microwave Symposium (IMS2015) - Phoenix, AZ, USA (2015.5.17-2015.5.22)] 2015 IEEE MTT-S International Microwave Symposium - A tunable notch filter using high-kt2 lithium niobate resonators toward integration in filter banks

Sean Yen,, Shi, Lisha, Piazza, Gianluca, Fedder, Gary K., Mukherjee, Tamal

Year:

2015

Language:

english

File:

PDF, 1.46 MB

english, 2015

67

Synthesis of Novel Tadalafil Analogues and their Evaluation as Phosphodiesterase Inhibitors and Anticancer Agents

Ashraf H, Abadi, Dalal A, Abouel-Ella, Nermin S, Ahmed, Bernard D, Gary, Jose T, Thaiparambil, Heather N, Tinsley, Adam B, Keeton, Gary A, Piazza

Journal:

Arzneimittelforschung

Year:

2011

Language:

english

File:

PDF, 347 KB

english, 2011

68

Chemoprevention in gastrointestinal physiology and disease. Anti-inflammatory approaches for colorectal cancer chemoprevention

Fajardo, Alexandra M., Piazza, Gary A.

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2015

File:

PDF, 198 KB

2015

69

MicroRNAs are involved in the self-renewal and differentiation of cancer stem cells

Wang, Zheng-ming, Du, Wen-jun, Piazza, Gary A, Xi, Yaguang

Journal:

Acta Pharmacologica Sinica

Year:

2013

Language:

english

File:

PDF, 256 KB

english, 2013

70

Bond-Bending Isomerism of Au2I3−: Competition between Covalent Bonding and Aurophilicity

Wang, Lai-Sheng, Li, Wan-Lu, Liu, Hong-Tao, Jian, Tian, Lopez, Gary V., Piazza, Zachary A, Huang, Dao-Ling, Chen, Teng-Teng, Su, Jing, Yang, Ping, Chen, Xin, Li, Jun

Journal:

Chemical Science

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

71

Chemoprevention in gastrointestinal physiology and disease. Anti-inflammatory approaches for colorectal cancer chemoprevention

Fajardo, Alexandra M., Piazza, Gary A.

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2015

Language:

english

File:

PDF, 198 KB

english, 2015

72

Rad6 upregulation promotes stem cell-like characteristics and platinum resistance in ovarian cancer

Somasagara, Ranganatha R., Tripathi, Kaushlendra, Spencer, Sebastian M., Clark, David W., Barnett, Reagan, Bachaboina, Lavanya, Scalici, Jennifer, Rocconi, Rodney P., Piazza, Gary A., Palle, Komaraiah

Journal:

Biochemical and Biophysical Research Communications

Year:

2016

Language:

english

File:

PDF, 1.40 MB

english, 2016

73

Incorporation of Hydrogen and Oxygen into (t)a-C:H Thin Films Deposited using DECR plasma (*)

Piazza, Fabrice, Grambole, Dieter, Herrmann, Folker, Relihan, Gary, Barthe, Marie France, Desgardin, Pierre, Golanski, André

Journal:

MRS Proceedings

Year:

2001

Language:

english

File:

PDF, 61 KB

english, 2001

74

CoMFA and CoMSIA Studies of 1,2-dihydropyridine Derivatives as Anticancer Agents

Salama, Ismail, A. O. Abdel-Fattah, Mohamed, S. Hany, Marwa, A. El-Sharif, Shaimaa, A. M. El-Naggar, Mahmoud, M. H. Rashied, Rasha, A. Piazza, Gary, H. Abadi, Ashraf

Journal:

Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 762 KB

english, 2012

75

A Novel Access to Arylated and Heteroarylated Beta-Carboline Based PDE5 Inhibitors

S. Ahmed, Nermin, D. Gary, Bernard, A. Piazza, Gary, N. Tinsley, Heather, Laufer, Stefan, H. Abadi, Ashraf

Journal:

Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 477 KB

english, 2010

76

ChemInform Abstract: Design of Novel β-Carboline Derivatives with Pendant 5-Bromothienyl and Their Evaluation as Phosphodiesterase-5 Inhibitors.

El-Gamil, Dalia S., Ahmed, Nermin S., Gary, Bernard D., Piazza, Gary A., Engel, Matthias, Hartmann, Rolf W., Abadi, Ashraf H.

Journal:

Year:

2013

File:

PDF, 26 KB

2013

77

ChemInform Abstract: Synthesis of Some Dihydropyrimidine-Based Compounds Bearing Pyrazoline Moiety and Evaluation of Their Antiproliferative Activity.

Awadallah, Fadi M., Piazza, Gary A., Gary, Bernard D., Keeton, Adam B., Canzoneri, Joshua C.

Journal:

Year:

2014

File:

PDF, 28 KB

2014

78

Metabolism and growth inhibitory activity of cranberry derived flavonoids in bladder cancer cells

Prasain, Jeevan K., Rajbhandari, Rajani, Keeton, Adam B., Piazza, Gary A., Barnes, Stephen

Journal:

Food & Function

Year:

2016

Language:

english

File:

PDF, 942 KB

english, 2016

79

Synthesis and Optimization of New 3,6-Disubstitutedindole Derivatives and Their Evaluation as Anticancer Agents Targeting the MDM2/MDMx Complex

Rezk, Mohamed Salah, Abdel-Halim, Mohammad, Keeton, Adam, Franklin, Derek, Bauer, Matthias, Boeckler, Frank Michael, Engel, Matthias, Hartmann, Rolf Wolfgang, Zhang, Yanping, Piazza, Gary Anthony, Aba

Year:

2016

Language:

english

File:

PDF, 851 KB

english, 2016

80

Modulating the Cyclic Guanosine Monophosphate Substrate Selectivity of the Phosphodiesterase 3 Inhibitors by Pyridine, Pyrido[2,3-d]pyrimidine Derivatives and Their Effects upon the Growth of HT-29 Cancer Cell Line

Abadi, Ashraf Hassan, Hany, Marwa Saeed, Elsharif, Shimaa Awadain, Eissa, Amal Abdel Haleem, Gary, Bernard DeWayne, Tinsley, Heather Nicole, Piazza, Gary Anthony

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2013

Language:

english

File:

PDF, 776 KB

english, 2013

81

The RAS–Effector Interaction as a Drug Target

Keeton, Adam B., Salter, E. Alan, Piazza, Gary A.

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 279 KB

english, 2017

82

Validation of PDE5 as a Chemoprevention Target

Piazza, Gary A.

Journal:

Cancer Prevention Research

Year:

2017

Language:

english

File:

PDF, 343 KB

english, 2017

83

[IEEE 2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS) - Kaohsiung, Taiwan (2017.6.18-2017.6.22)] 2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS) - Reconfigurable AlN resonator filter design based on extended statistical element selection

Xu, Jinglin, Merugu, Srinivas, Singh, Navab, Piazza, Gianluca, Pileggi, Lawrence, Fedder, Gary K.

Year:

2017

Language:

english

File:

PDF, 2.85 MB

english, 2017

84

Considerations in Comparing Intravenous and Intramuscular Antibiotics

Milkovich, Gary, Piazza, Christopher J.

Journal:

Year:

1991

File:

PDF, 2.03 MB

1991

85

Design and synthesis of novel annulated thienopyrimidines as phosphodiesterase 5 (PDE5) inhibitors

El-Sharkawy, Lina Y., El-Sakhawy, Rowaida A., Abdel-Halim, Mohammad, Lee, Kevin, Piazza, Gary A., Ducho, Christian, Hartmann, Rolf W., Abadi, Ashraf H.

Journal:

Archiv der Pharmazie

Year:

2018

Language:

english

File:

PDF, 2.55 MB

english, 2018

86

[IEEE 2017 IEEE International Ultrasonics Symposium (IUS) - Washington, DC (2017.9.6-2017.9.9)] 2017 IEEE International Ultrasonics Symposium (IUS) - Self-healing narrowband filters via 3D heterogeneous integration of AlN MEMS and CMOS chips

Calayir, Enes, Merugu, Srinivas, Xu, Jinglin, Singh, Navab, Pileggi, Larry, Piazza, Gianluca, Fedder, Gary K.

Year:

2017

Language:

english

File:

PDF, 657 KB

english, 2017

87

[IEEE 2017 IEEE International Ultrasonics Symposium (IUS) - Washington, DC (2017.9.6-2017.9.9)] 2017 IEEE International Ultrasonics Symposium (IUS) - Self-healing narrowband filters via 3D heterogeneous integration of AlN MEMS and CMOS chips

Calayir, Enes, Xu, Jinglin, Pileggi, Larry, Fedder, Gary K., Merugu, Srinivas, Singh, Navab, Piazza, Gianluca

Year:

2017

Language:

english

File:

PDF, 78 KB

english, 2017

88

Panepoxydone Targets NF-kB and FOXM1 to Inhibit Proliferation, Induce Apoptosis and Reverse Epithelial to Mesenchymal Transition in Breast Cancer

Arora, Ritu, Yates, Clayton, Gary, Bernard D., McClellan, Steven, Tan, Ming, Xi, Yaguang, Reed, Eddie, Piazza, Gary A., Owen, Laurie B., Dean-Colomb, Windy, Samant, Rajeev

Journal:

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

89

New hydrazonoindolin-2-ones: Synthesis, exploration of the possible anti-proliferative mechanism of action and encapsulation into PLGA microspheres

Attia, Mohamed I., Eldehna, Wagdy M., Afifi, Samar A., Keeton, Adam B., Piazza, Gary A., Abdel-Aziz, Hatem A., Filleur, Stéphanie

Journal:

Year:

2017

Language:

english

File:

PDF, 3.32 MB

english, 2017

90

NSAIDs: Old Drugs Reveal New Anticancer Targets

Piazza, Gary A., Keeton, Adam B., Tinsley, Heather N., Whitt, Jason D., Gary, Bernard D., Mathew, Bini, Singh, Raj, Grizzle, William E., Reynolds, Robert C.

Journal:

Pharmaceuticals

Year:

2010

Language:

english

File:

PDF, 443 KB

english, 2010

91

Structure-Based Design of Novel Tetrahydro-Beta-Carboline Derivatives with a Hydrophilic Side Chain as Potential Phosphodiesterase Inhibitors

Elhady, Ahmed, Sigler, Sara, Noureldin, Nazih, Canzoneri, Joshua, Ahmed, Nermin, Piazza, Gary, Abadi, Ashraf

Journal:

Scientia Pharmaceutica

Year:

2015

Language:

english

File:

PDF, 3.40 MB

english, 2015

92

Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling

Abdel-Aziz, Hatem, Eldehna, Wagdy, Keeton, Adam, Piazza, Gary, Kadi, Adnan, Attwa, Mohamed, Abdelhameed, Ali, Attia, Mohamed

Journal:

Drug Design Development and Therapy

Year:

2017

Language:

english

File:

PDF, 1.19 MB

english, 2017

93

Design and synthesis of 1,2,4‐triazolo[1,5‐ a ]pyrimidine derivatives as PDE 4B inhibitors endowed with bronchodilator activity

Abd El‐Aleam, Rehab H., George, Riham F., Lee, Kevin J., Keeton, Adam B., Piazza, Gary A., Kamel, Amr A., El‐Daly, Mahmoud E., Hassan, Ghaneya S., Abdel‐Rahman, Hamdy M.

Journal:

Archiv der Pharmazie

Year:

2019

Language:

english

File:

PDF, 1.25 MB

english, 2019

94

Antiproliferative activity and possible mechanism of action of certain 5-methoxyindole tethered C-5 functionalized isatins

Almutairi, Maha S., Hassan, Eman S., Keeton, Adam B., Piazza, Gary A., Abdelhameed, Ali S., Attia, Mohamed I.

Journal:

Drug Design Development and Therapy

Year:

2019

Language:

english

File:

PDF, 947 KB

english, 2019

95

Antiproliferative activity and possible mechanism of action of certain 5-methoxyindole tethered C-5 functionalized isatins

Almutairi, Maha S., Hassan, Eman S., Keeton, Adam B., Piazza, Gary A., Abdelhameed, Ali S., Attia, Mohamed I.

Journal:

Drug Design Development and Therapy

Year:

2019

File:

PDF, 947 KB

2019

96

Exploiting RAS Nucleotide Cycling as a Strategy for Drugging RAS-Driven Cancers

Mattox, Tyler E., Chen, Xi, Maxuitenko, Yulia Y., Keeton, Adam B., Piazza, Gary A.

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 1.02 MB

english, 2019

97

Exploiting RAS Nucleotide Cycling as a Strategy for Drugging RAS-Driven Cancers

Mattox, Tyler E., Chen, Xi, Maxuitenko, Yulia Y., Keeton, Adam B., Piazza, Gary A.

Journal:

International Journal of Molecular Sciences

Year:

2019

File:

PDF, 1.02 MB

2019

98

Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors

ElHady, Ahmed K., Shih, Shou-Ping, Chen, Yu-Cheng, Liu, Yi-Chang, Ahmed, Nermin S., Keeton, Adam B., Piazza, Gary A., Engel, Matthias, Abadi, Ashraf H., Abdel-Halim, Mohammad

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 3.20 MB

2020

99

Targeting cGMP/PKG signaling for the treatment or prevention of colorectal cancer with novel sulindac derivatives lacking cyclooxygenase inhibitory activity

Piazza, Gary A., Chen, Xi, Ward, Antonio, Coley, Alex, Zhou, Gang, Buchsbaum, Donald J., Maxuitenko, Yulia, Keeton, Adam B.

Journal:

Oncology Signaling

Year:

2020

File:

PDF, 579 KB

2020

100

PDE5 and PDE10 inhibition activates cGMP/PKG signaling to block Wnt/Î²-catenin transcription, cancer cell growth, and tumor immunity

Piazza, Gary A., Ward, Antonio, Chen, Xi, Maxuitenko, Yulia, Coley, Alex, Aboelella, Nada S., Buchsbaum, Donald J., Boyd, Michael R., Keeton, Adam B., Zhou, Gang

Journal:

Drug Discovery Today

Year:

2020

File:

PDF, 912 KB

2020

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