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51

Ca2+-Dependent Cytoprotective Effects of Ursodeoxycholic and Tauroursodeoxycholic Acid on the Biliary Epithelium in a Rat Model of Cholestasis and Loss of Bile Ducts

Marco Marzioni, Heather Francis, Antonio Benedetti, Yoshiyuki Ueno, Giammarco Fava, Juliet Venter, Ramona Reichenbach, Maria Grazia Mancino, Ryun Summers, Gianfranco Alpini, Shannon Glaser

Journal:

The American Journal of Pathology

Year:

2006

Language:

english

File:

PDF, 1.09 MB

english, 2006

52

Estrogens and Insulin-Like Growth Factor 1 Modulate Neoplastic Cell Growth in Human Cholangiocarcinoma

Domenico Alvaro, Barbara Barbaro, Antonio Franchitto, Paolo Onori, Shannon S. Glaser, Gianfranco Alpini, Heather Francis, Luca Marucci, Paola Sterpetti, Stefano Ginanni-Corradini, Andrea Onetti Muda,

Journal:

The American Journal of Pathology

Year:

2006

Language:

english

File:

PDF, 1.91 MB

english, 2006

53

Morphological and Functional Features of Hepatic Cyst Epithelium in Autosomal Dominant Polycystic Kidney Disease

Domenico Alvaro, Paolo Onori, Gianfranco Alpini, Antonio Franchitto, Douglas M. Jefferson, Alessia Torrice, Vincenzo Cardinale, Fabrizio Stefanelli, Maria Grazia Mancino, Mario Strazzabosco, Mario Ang

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 2.39 MB

english, 2008

54

Prostate Apoptosis Response-4 Is Expressed in Normal Cholangiocytes, Is Down-Regulated in Human Cholangiocarcinoma, and Promotes Apoptosis of Neoplastic Cholangiocytes When Induced Pharmacologically

Antonio Franchitto, Alessia Torrice, Rossella Semeraro, Cristina Napoli, Gennaro Nuzzo, Felice Giuliante, Gianfranco Alpini, Guido Carpino, Pasquale Bartolomeo Berloco, Luciano Izzo, Antonio Bolognese

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 1019 KB

english, 2010

55

Bile acid feeding induces cholangiocyte proliferation and secretion: Evidence for bile acid–regulated ductal secretion

Gianfranco Alpini*, ‡, §, Shannon S. Glaser*, Yoshiyuki Ueno¶, Rebecca Rodgers*, Jo Lynne Phinizy*, Heather Francis*, Leonardo Baiocchi*, Leigh A. Holcomb§, ∥, Alessandra Caligiuri*, Gene D. LeSage*

Journal:

Gastroenterology

Year:

1999

Language:

english

File:

PDF, 265 KB

english, 1999

56

Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats

Leonardo Baiocchi, Gianfranco Alpini, Shannon Glaser, Mario Angelico, Domenico Alvaro, Heather Francis, Marco Marzioni, Jo Lynne Phinizy, Barbara Barbaro, Gene LeSage

Journal:

Journal of Hepatology

Year:

2003

Language:

english

File:

PDF, 405 KB

english, 2003

57

Estrogens induce cholangiocyte proliferation through the activation of the ERK1/2 system and the adapter proteins Sch, and Src

Domenico Alvaro, Gianfranco Alpini, Paolo Onori, Antonio Franchitto, Shannon Glaser, Gene Le Sage, Alessandro Gigliozzi, Adolfo Attili, Gianluca Svegliati Baronigaudio, Veronica Drudi Metalli, Maria G

Journal:

Journal of Hepatology

Year:

2002

Language:

english

File:

PDF, 175 KB

english, 2002

58

Effect of ovariectomy on the proliferative capacity of intrahepatic rat cholangiocytes

Domenico Alvaro, Gianfranco Alpini, Paolo Onori, Antonio Franchitto, Shannon Glaser, Gene Le Sage, Alessandro Gigliozzi, Adolfo Attili, Eugenio Gaudio

Journal:

Journal of Hepatology

Year:

2002

Language:

english

File:

PDF, 111 KB

english, 2002

59

Gamma-interferon inhibits secretin-induced choleresis and cholangiocyte proliferation in a murine model of cirrhosis

Gianfranco Alpini, Ivan Elias, Shannon S. Glaser, Rebecca E.D. Rodgers, Jo Lynne Phinizy, Willie E. Robertson, Heather Francis, John Lasater, Mark Richards, Gene D. LeSage

Journal:

Journal of Hepatology

Year:

1997

Language:

english

File:

PDF, 1.29 MB

english, 1997

60

Regulation of cholangiocyte bile secretion

Leonardo Baiocchi, Gene LeSage, Shannon Glaser, Gianfranco Alpini

Journal:

Journal of Hepatology

Year:

1999

Language:

english

File:

PDF, 1.66 MB

english, 1999

61

Expression of platelet-derived growth factor in newly formed cholangiocytes during experimental biliary fibrosis in rats

Cecilia Grappone, Massimo Pinzani, Maurizio Parola, Giulia Pellegrini, Alessandra Caligiuri, Raffaella DeFranco, Fabio Marra, Hermann Herbst, Gianfranco Alpini, Stefano Milani

Journal:

Journal of Hepatology

Year:

1999

Language:

english

File:

PDF, 1.75 MB

english, 1999

62

Gastrin reverses established cholangiocyte proliferation and enhanced secretin-stimulated ductal secretion of BDL rats by activation of apoptosis through increased expression of Ca2+-dependent PKC isoforms

Shannon Glaser, Domenico Alvaro, Yoshiyuki Ueno, Heather Francis, Marco Marzioni, Jo Lynne Phinizy, Brandy Baumann, Maria Grazia Mancino, Julie Venter, Gene LeSage, Gianfranco Alpini

Journal:

Liver International

Year:

2003

Language:

english

File:

PDF, 244 KB

english, 2003

63

Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha

Gianfranco Alpini, Leonardo Baiocchi, Shannon Glaser, Yoshiyuki Ueno, Marco Marzioni, Heather Francis, Jo Lynne Phinizy, Mario Angelico, Gene LeSage

Journal:

Year:

2002

Language:

english

File:

PDF, 471 KB

english, 2002

64

Hepatic progenitor cells activation, fibrosis, and adipokines production in pediatric nonalcoholic fatty liver disease

Nobili, Valerio, Carpino, Guido, Alisi, Anna, Franchitto, Antonio, Alpini, Gianfranco, De Vito, Rita, Onori, Paolo, Alvaro, Domenico, Gaudio, Eugenio

Journal:

Year:

2012

Language:

english

File:

PDF, 1.77 MB

english, 2012

65

Liver X receptor β and peroxisome proliferator-activated receptor δ regulate cholesterol transport in murine cholangiocytes

Xia, Xuefeng, Jung, Dongju, Webb, Paul, Zhang, Aijun, Zhang, Bin, Li, Lifei, Ayers, Stephen D., Gabbi, Chiara, Ueno, Yoshiyuki, Gustafsson, Jan-Åke, Alpini, Gianfranco, Moore, David D., LeSage, Gene D

Journal:

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

66

Recent advances in the regulation of cholangiocyte proliferation and function during extrahepatic cholestasis

Shannon S. Glaser, Paolo Onori, Candace Wise, Fuguan Yang, Marco Marzioni, Domenico Alvaro, Antonio Franchitto, Romina Mancinelli, Gianfranco Alpini, Md. Kamruzzaman Munshi, Eugenio Gaudio

Journal:

Digestive and Liver Disease

Year:

2010

Language:

english

File:

PDF, 1.24 MB

english, 2010

67

Introduction to Mini-Symposium on Cholangiocyte Pathophysiology—Part I

Gianfranco Alpini

Journal:

Digestive and Liver Disease

Year:

2010

Language:

english

File:

PDF, 83 KB

english, 2010

68

Introduction to Mini-Symposium on Cholangiocyte Pathophysiology—Part II

Shannon S. Glaser, Gianfranco Alpini

Journal:

Digestive and Liver Disease

Year:

2010

Language:

english

File:

PDF, 87 KB

english, 2010

69

Polycystins play a key role in the modulation of cholangiocyte proliferation

Alessia Torrice, Vincenzo Cardinale, Manuela Gatto, Rossella Semeraro, Cristina Napoli, Paolo Onori, Gianfranco Alpini, Eugenio Gaudio, Domenico Alvaro

Journal:

Digestive and Liver Disease

Year:

2010

Language:

english

File:

PDF, 840 KB

english, 2010

70

Tannic acid inhibits cholangiocyte proliferation of bile duct ligated (BDL) rats by Ca2+- and Pkc-dependent mechanisms

Silvia Taffetani, Carla Marienfeld, Gianfranco Alpini, Tushar Patel

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 161 KB

english, 2003

71

Bile acid stimulation of small bile duct proliferation requires de novo expression of the apical bile acid transporter (ABAT)

Gianfranco Alpini, Shannon Glaser, Jo Lynne Phinizy, Noriatsu Kanno, Heather Francis, Mikel Ludvik, Gene Lesage

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 189 KB

english, 2001

72

Regulation of cholanglocyte apical bile acid transporter (ABAT) activity by biliary bile acids: Different potential compensatory changes for intrahepatic and extrahepatic cholestasis

Gianfranco Alpini, Shannon Glaser, Jo Lynne Phinizy, Noriatsu Kanno, Heather Francis, Mikel Ludvik, Gene Lesage

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 176 KB

english, 2001

73

The growth of two human cholangiocarcinoma cell lines is inhibited by alpha-2 adrenergic agonists by a cAMP-dependent mechanism through the inhibition of Raf-1 and MAPK systems

Noriatsu Kanno, Gene Lesage, Shannon Glaser, Jo Lynne Phinizy, Mikel Ludvik, Gianfranco Alpini

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 187 KB

english, 2001

74

Gastrin inhibits cholangiocarcinoma growth through increased apoptosis by activation of Ca2+-dependent protein kinase C-α

Noriatsu Kanno, Shannon Glaser, Usha Chowdhury, Jo Lynne Phinizy, Leonardo Baiocchi, Heather Francis, Gene LeSage, Gianfranco Alpini

Journal:

Journal of Hepatology

Year:

2001

Language:

english

File:

PDF, 1.28 MB

english, 2001

75

28 Taurocholate feeding prevents the functional damage of intrahepatic bile ducts induced by adrenergic denervation in a PI3K dependent manner

Marco Marzioni, Shannon Glaser, Heather Francis, Silvia Taffetani, Luca Marucci, Antonio Benedetti, Domenico Alvaro, Jo Lynne Phinizy, Brandy Baumann, Julie Venter, Yoshiyuki Ueno, Gianfranco Alpini

Journal:

Year:

2003

Language:

english

File:

PDF, 148 KB

english, 2003

76

869 The bile acid taurocholic acid protects against TNF-alpha induced cholangiocyte apoptosis in bile duct ligated (BDL) rats by activation of the PI3K/AKT-dependent pathway

Silvia Taffetani, Shannon Glaser, Heather Francis, Yoshiyuki Ueno, Tushar Patel, Jo Lynne Phinizy, Marco Marzioni, Antonio Benedetti, Giammarco Fava, Brandy Baumann, Julie Venter, Gianfranco Alpini

Journal:

Year:

2003

Language:

english

File:

PDF, 267 KB

english, 2003

77

28 Activation of serotonin receptor 5-HT1A and 5-HT1B subtypes inhibits cholangiocyte proliferation and secretion of dile duct ligated (BDL) rats in a cAMP/PKA/SRC/ERK1/2 dependent manner

Marco Marzioni, Gianfranco Alpini, Luca Marucci, Brandy Baumarun, Heather Francis, Shannon Glaser, Antonio Di Sario, Antonio Benedetti

Journal:

Digestive and Liver Disease

Year:

2003

Language:

english

File:

PDF, 159 KB

english, 2003

78

Estrogens Stimulate Proliferation of Intrahepatic Biliary Epithelium in Rats

Domenico Alvaro*, Gianfranco Alpini‡, Paolo Onori§, Lucia Perego‖, Gianluca Svegliati Baroni¶, Antonio Franchitto§, Leonardo Baiocchi‡, Shannon S. Glaser‡, Gene Le Sage‡, Franco Folli‖, Eugenio Gaudio

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 647 KB

english, 2000

79

Corticosteroids modulate the secretory processes of the rat intrahepatic biliary epithelium

Domenico Alvaro, Alessandro Gigliozzi, Luca Marucci, Gianfranco Alpini, Barbara Barbaro, Rita Monterubbianesi, Lara Minetola, Maria Grazia Mancino, Juan F. Medina, Adolfo F. Attili, Antonio Benedetti

Journal:

Gastroenterology

Year:

2002

Language:

english

File:

PDF, 4.99 MB

english, 2002

80

Effect of ovariectomy on the proliferative capacity of intrahepatic rat cholangiocytes

Domenico Alvaro, Gianfranco Alpini, Paolo Onori, Antonio Franchitto, Shannon Glaser, Gene Le Sage, Alessandro Gigliozzi, Antonella Vetuschi, Sergio Morini, Adolfo F. Attili, Eugenio Gaudio

Journal:

Gastroenterology

Year:

2002

Language:

english

File:

PDF, 699 KB

english, 2002

81

Bile acid depletion and repletion regulate cholangiocyte growth and secretion by a phosphatidylinositol 3-kinase–dependent pathway in rats

Gianfranco Alpini, Shannon Glaser, Domenico Alvaro, Yoshiyuki Ueno, Marco Marzioni, Heather Francis, Leonardo Baiocchi, Tonino Stati, Barbara Barbaro, Jo Lynne Phinizy, Jeremy Mauldin, Gene LeSage

Journal:

Gastroenterology

Year:

2002

Language:

english

File:

PDF, 460 KB

english, 2002

82

Nerve growth factor modulates the proliferative capacity of the intrahepatic biliary epithelium in experimental cholestasis

Alessandro Gigliozzi, Gianfranco Alpini, Gianluca Svegliati Baroni, Luca Marucci, Veronica Drudi Metalli, Shannon S. Glaser, Heather Francis, Maria Grazia Mancino, Yoshiyuki Ueno, Barbara Barbaro, Ant

Journal:

Gastroenterology

Year:

2004

Language:

english

File:

PDF, 675 KB

english, 2004

83

Endogenous Opioids Modulate the Growth of the Biliary Tree in the Course of Cholestasis

Marco Marzioni, Gianfranco Alpini, Stefania Saccomanno, Samuele de Minicis, Shannon Glaser, Heather Francis, Luciano Trozzi, Juliet Venter, Fiorenza Orlando, Giammarco Fava, Cinzia Candelaresi, Giampi

Journal:

Gastroenterology

Year:

2006

Language:

english

File:

PDF, 3.12 MB

english, 2006

84

Proliferating Cholangiocytes: A Neuroendocrine Compartment in the Diseased Liver

Domenico Alvaro, Maria Grazia Mancino, Shannon Glaser, Eugenio Gaudio, Marco Marzioni, Heather Francis, Gianfranco Alpini

Journal:

Gastroenterology

Year:

2007

Language:

english

File:

PDF, 959 KB

english, 2007

85

Glucagon-Like Peptide-1 and Its Receptor Agonist Exendin-4 Modulate Cholangiocyte Adaptive Response to Cholestasis

Marco Marzioni, Gianfranco Alpini, Stefania Saccomanno, Cinzia Candelaresi, Juliet Venter, Chiara Rychlicki, Giammarco Fava, Heather Francis, Luciano Trozzi, Shannon Glaser, Antonio Benedetti

Journal:

Gastroenterology

Year:

2007

Language:

english

File:

PDF, 1.49 MB

english, 2007

86

The biliary tree—a reservoir of multipotent stem cells

Cardinale, Vincenzo, Wang, Yunfang, Carpino, Guido, Mendel, Gemma, Alpini, Gianfranco, Gaudio, Eugenio, Reid, Lola M., Alvaro, Domenico

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Year:

2012

Language:

english

File:

PDF, 1.24 MB

english, 2012

87

[Vitamins & Hormones] Vitamins and Hormones Volume 81 || Chapter 18 Changes in the Endocannabinoid System May Give Insight into new and Effective Treatments for Cancer

Alpini, Gianfranco

Year:

2009

Language:

english

File:

PDF, 296 KB

english, 2009

88

FXR-induced secretion of FGF15/19 inhibits CYP27 expression in cholangiocytes through p38 kinase pathway

Jung, Dongju, York, J. Philippe, Wang, Li, Yang, Chaofeng, Zhang, Aijun, Francis, Heather L., Webb, Paul, McKeehan, Wallace L., Alpini, Gianfranco, LeSage, Gene D., Moore, David D., Xia, Xuefeng

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

89

342 Novel Evidence for An Autocrine Mechanism By Which Neuropeptide Y Inhibits Cholangiocarcinoma Growth In Vitro and In Vivo

Coufal, Monique, Gaudio, Eugenio, Carpino, Guido, Kopriva, Shelley, Venter, Julie, Onori, Paolo, Franchitto, Antonio, Francis, Heather, White, Mellanie, Fava, Giammarco, Alpini, Gianfranco, DeMorrow,

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 74 KB

english, 2009

90

740 Epigenetic Regulation of MicroRNA-200 Family in Human Gall Bladder Cancer Stem Cells

Han, Yuyan, Francis, Heather L., Glaser, Shannon, McCarra, Jennifer, Alpini, Gianfranco, Sharma, Jay, Dusio, Giuseppina, Liu, Chang-Gong, Johnson, Christopher, Meng, Fanyin

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 205 KB

english, 2012

91

Bile acid absorption in isolated bile duct units (IBDU) is primarily due to the apical bile acid transporter

Alpini, Gianfranco, Glaser, Shannon, Phinizy, Jo Lynne, Hofmann, Alan F., LeSage, Gene

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 199 KB

english, 2000

92

292 Functional Roles of MicroRNAs in Mechanical Stress Induced Mesenchymal Transition During Cholestatic Liver Injury

Meng, Fanyin, Jensen, Kendal J., Afroze, Syeda, Han, Yuyan, Munshi, Mk, Alpini, Gianfranco, Guerrier, Micheleine, Dostal, David E., Glaser, Shannon

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

93

Mo1778 Regulation of MicroRNAs by p53 in Functional Tumor-Initiating Cells of Human Gallbladder Cancer

Levine, Phillip, McDaniel, Kelly, Francis, Heather L., Glaser, Shannon, Han, Yuyan, Sharma, Jay, Liu, Chang-Gong, Venter, Julie, Short-Baker, Kimberly K., Alpini, Gianfranco, Meng, Fanyin

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 55 KB

english, 2013

94

Sa1698 Downregulation of Menin by Mir-24-1 Increases Cholangiocarcinoma Proliferation

Lairmore, Terry, Ammarzahid, Hassan, Maté, Gergely, Standeford, Holly A., Venter, Julie, Meng, Fanyin, Afroze, Syeda H., Guerrier, Micheleine, Avila, Shanika, Alpini, Gianfranco, Glaser, Shannon

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 59 KB

english, 2014

95

368 Regulation of MicroRNA Expression by Secretin During Cholestatic Liver Injury

Johnson, Christopher, Han, Yuyan, Meng, Fanyin, Francis, Heather L., Venter, Julie, McDaniel, Kelly, Onori, Paolo, Ueno, Yoshiyuki, Gaudio, Eugenio, Glaser, Shannon, Alpini, Gianfranco

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 53 KB

english, 2013

96

698 Signal Transducer and Activator of Transcription (STAT)-3 Regulates MicroRNA Gene Expression in Alcoholic Steatohepatitis

Milad, Mena, McDaniel, Kelly, Han, Yuyan, Quezada, Morgan, Francis, Heather L., Glaser, Shannon, Venter, Julie, Alpini, Gianfranco, Meng, Fanyin

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 161 KB

english, 2014

97

931 Regulation of Hepatic Stem/Progenitor Phenotype by Melatonin During Alcoholic Liver Injury

Han, Yuyan, Glaser, Shannon, McCarra, Jennifer, Venter, Julie, White, Mellanie, Dusio, Giuseppina, Francis, Heather L., Johnson, Christopher, Tsukamoto, Hidekazu, Meng, Fanyin, Alpini, Gianfranco

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 57 KB

english, 2012

98

646 Translational Control of the Circadian Rhythms by MicroRNA-34a in Human Cholangiocarcinoma

Han, Yuyan, Meng, Fanyin, Glaser, Shannon, Venter, Julie, McDaniel, Kelly, Francis, Heather L., Alpini, Gianfranco

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 180 KB

english, 2014

99

Su1718 Regulation of MicroRNA-21 by Interleukin-6 During Alcoholic Liver Injury

Levine, Phillip, McDaniel, Kelly, Han, Yuyan, Francis, Heather L., Glaser, Shannon, Venter, Julie, Tsukamoto, Hidekazu, Alpini, Gianfranco, Meng, Fanyin

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 158 KB

english, 2013

100

473 Functional Role of Definitive Endoderm Marker FOXA2 in Biliary-Committed Progenitor Cells During Cholestatic Liver Injury

McDaniel, Kelly, Han, Yuyan, Glaser, Shannon, Francis, Heather L., Venter, Julie, Guerrier, Micheleine, Meng, Fanyin, Alpini, Gianfranco

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 283 KB

english, 2014