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1

Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases, blocks the growth of HER2-overexpressing human breast cancer cells

Marianna Zavodovskaya, Michael J. Campbell, Betty A. Maddux, Laura Shiry, Geoffrey Allan, Leslie Hodges, Peter Kushner, John A. Kerner, Jack F. Youngren, Ira D. Goldfine

Journal:

Journal of Cellular Biochemistry

Year:

2008

Language:

english

File:

PDF, 268 KB

english, 2008

2

Nordihydroguaiaretic Acid (NDGA) Inhibits the IGF-1 and c-erbB2/HER2/neu Receptors and Suppresses Growth in Breast Cancer Cells

Jack F. Youngren, Karissa Gable, Cristina Penaranda, Betty A. Maddux, Marianna Zavodovskaya, Margaret Lobo, Michael Campbell, John Kerner, Ira D. Goldfine

Journal:

Breast Cancer Research and Treatment

Year:

2005

Language:

english

File:

PDF, 330 KB

english, 2005

3

The endocrine secretion of human insulin and growth hormone by exocrine glands of the gastrointestinal tract

Goldfine, Ira D., German, Michael S., Tseng, Hsien-Chen, Wang, Juemin, Bolaffi, Janice L., Chen, Je-Wei, Olson, David C., Rothman, Stephen S.

Journal:

Nature Biotechnology

Year:

1997

File:

PDF, 710 KB

1997

4

Cerebral Salt Wasting Syndrome: Diagnosis By Urine Sodium Excretion

Arieff, Allen I., Gabbai, Ramin, Goldfine, Ira D.

Journal:

The American Journal of the Medical Sciences

Year:

2017

Language:

english

File:

PDF, 674 KB

english, 2017

5

Insulin-stimulated cell growth in insulin receptor substrate-1–deficient ZR-75-1 cells is mediated by a phosphatidylinositol-3-kinase–independent pathway

Biancamaria Gliozzo, Chin K. Sung, PierLuigi Scalia, Vincenzo Papa, Francesco Frasca, Laura Sciacca, Francesco Giorgino, Giovanni Milazzo, Ira D. Goldfine, Riccardo Vigneri, Vincenzo Pezzino

Journal:

Journal of Cellular Biochemistry

Year:

1998

Language:

english

File:

PDF, 149 KB

english, 1998

6

ASPB10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: Evidence for enhanced interactions with the insulin-like growth factor-I receptor

Giovanni Milazzo, Laura Sciacca, Vincenzo Papa, Ira D. Goldfine, Riccardo Vigneri

Journal:

Molecular Carcinogenesis

Year:

1997

Language:

english

File:

PDF, 128 KB

english, 1997

7

Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes

Cesar A. Albarracin, Burcham C. Fuqua, Joseph L. Evans, Ira D. Goldfine

Journal:

Diabetes/Metabolism Research and Reviews

Year:

2008

Language:

english

File:

PDF, 186 KB

english, 2008

8

In vitro and in vivo prevention of HIV protease inhibitor-induced insulin resistance by a novel small molecule insulin receptor activator

Mingshan Cheng, Seiyu Chen, Steven R. Schow, Vara Prasad Manchem, Wayne R. Spevak, Cristina P. Cristobal, Songyuan Shi, Robert W. Macsata, Robert T. Lum, Ira D. Goldfine, James G. Keck

Journal:

Journal of Cellular Biochemistry

Year:

2004

Language:

english

File:

PDF, 264 KB

english, 2004

9

Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells

Gary E. Meyer, Louis Chesler, Dandan Liu, Karissa Gable, Betty A. Maddux, David D. Goldenberg, Jack F. Youngren, Ira D. Goldfine, William A. Weiss, Katherine K. Matthay, Stephen M. Rosenthal

Journal:

Journal of Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 304 KB

english, 2007

10

The effect of phenformin and other adenosine triphosphate (ATP)-lowering agents on insulin binding to IM-9 human cultured lymphocytes

Riccardo Vigneri, Betty Maddux, Ira D. Goldfine

Journal:

Journal of Cellular Biochemistry

Year:

1984

Language:

english

File:

PDF, 568 KB

english, 1984

11

Insulin secretion and action and diabetes mellitus

Ira D. Goldfine, Paul Pilch

Journal:

Journal of Cellular Biochemistry

Year:

1992

Language:

english

File:

PDF, 196 KB

english, 1992

12

A monoclonal antibody to the T-cell receptor increases IGF-I receptor content in normal T-lymphocytes: Comparison with phytohemagglutinin

Klaus K. P. Hartmann, Vincenzo Papa, Eric J. Brown, Ira D. Goldfine, Stephen M. Rosenthal, Thomas G. Baier, Michael Kronenwett

Journal:

Journal of Cellular Biochemistry

Year:

1992

Language:

english

File:

PDF, 467 KB

english, 1992

13

Insulin receptor overexpression in 184B5 human mammary epithelial cells induces a ligand-dependent transformed phenotype

Lucia Frittitta, Riccardo Vigneri, Martha R. Stampfer, Ira D. Goldfine

Journal:

Journal of Cellular Biochemistry

Year:

1995

Language:

english

File:

PDF, 348 KB

english, 1995

14

Technical evaluation of in vivo abdominal fat and IMCL quantification using MRI and MRSI at 3 T

Xiaojuan Li, Jack F. Youngren, Ben Hyun, Giorgos K. Sakkas, Kathleen Mulligan, Sharmila Majumdar, Umesh B. Masharani, Morris Schambelan, Ira D. Goldfine

Journal:

Magnetic Resonance Imaging

Year:

2008

Language:

english

File:

PDF, 629 KB

english, 2008

15

Structure-based de novo design of ligands using a three-dimensional model of the insulin receptor

Christopher Tan, Lianhu Wei, F.Peter Ottensmeyer, Ira Goldfine, Betty A. Maddux, Cecil C. Yip, Robert A. Batey, Lakshmi P. Kotra

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 223 KB

english, 2004

16

Inhibitory effects of nordihydroguaiaretic acid (NDGA) on the IGF-1 receptor and androgen dependent growth of LAPC-4 prostate cancer cells

Charles J. Ryan, Marianna Zavodovskaya, Jack F. Youngren, Michael Campbell, Marc Diamond, Jeremy Jones, Laura Shiry, Geoffrey Allan, Betty A. Maddux, Ira D. Goldfine

Journal:

Year:

2008

Language:

english

File:

PDF, 275 KB

english, 2008

17

Progestin regulation of insulin and insulin-like growth factor I receptors in cultured human breast cancer cells

Ira D. Goldfine, Vincenzo Papa, Riccardo Vigneri, Pentti Siiteri, Stephen Rosenthal

Journal:

Breast Cancer Research and Treatment

Year:

1992

Language:

english

File:

PDF, 1012 KB

english, 1992

18

A pilot dose-escalation study of the effects of nordihydroguareacetic acid on hormone and prostate specific antigen levels in patients with relapsed prostate cancer

Charles J. Ryan, Andrea H. Harzstark, Jonathan Rosenberg, Amy Lin, Christina Claros, Ira D. Goldfine, John F. Kerner, Eric J. Small

Journal:

BJU International

Year:

2008

Language:

english

File:

PDF, 93 KB

english, 2008

19

Characterization of Receptors for Cholecystokinin and Related Peptides in Mouse Cerebral Cortex

Atsushi Saito, Ira D. Goldfine, John A. Williams

Journal:

Journal of Neurochemistry

Year:

1981

Language:

english

File:

PDF, 720 KB

english, 1981

20

Alterations of Brain Cholecystokinin Receptors in Mice Made Obese with Goldthioglucose

Atsushi Saito, John A. Williams, Samuel H. Waxier, Ira D. Goldfine

Journal:

Journal of Neurochemistry

Year:

1982

Language:

english

File:

PDF, 387 KB

english, 1982

21

Role of PC-1 in The Etiology of Insulin Resistance

IRA D. GOLDFINE, BETTY A. MADDUX, JACK F. YOUNGREN, VINCENZO TRISCHITTA, LUCIA FRITTITTA

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 548 KB

english, 1999

22

Inhibition of Cyclic 3′,5′-AMP Phosphodiesterase in Islet Cells and Other Tissues by Tolbutamide

GOLDFINE, IRA D., PERLMAN, ROBERT, ROTH, JESSE

Journal:

Year:

1971

File:

PDF, 426 KB

1971

23

Intracellular binding sites for insulin are immunologically distinct from those on the plasma membrane

GOLDFINE, IRA D., VIGNERI, RICCARDO, COHEN, DAVID, PLIAM, NATHAN B., KAHN, C. RONALD

Journal:

Year:

1977

File:

PDF, 387 KB

1977

24

Gender Differences in the Relationship of ENPP1/PC-1 Variants to Obesity in a Turkish Population

Sinan Tanyolaç, Robert W. Mahley, Uğur Hodoglugil, Ira D. Goldfine

Journal:

Year:

2008

Language:

english

File:

PDF, 178 KB

english, 2008

25

Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanism

Sciacca, Laura, Costantino, Angela, Pandini, Giuseppe, Mineo, Rossana, Frasca, Francesco, Scalia, Pierluigi, Sbraccia, Paolo, Goldfine, Ira D, Vigneri, Riccardo, Belfiore, Antonino

Journal:

Year:

1999

Language:

english

File:

PDF, 186 KB

english, 1999

26

Membrane glycoprotein PC-1 and insulin resistance

Ira D. Goldfine, Betty A. Maddux, Jack F. Youngren, Lucia Frittitta, Vincenzo Trischitta, G. Lynis Dohm

Journal:

Molecular and Cellular Biochemistry

Year:

1998

Language:

english

File:

PDF, 271 KB

english, 1998

27

Parallel Synthesis of Diarylureas and Their Evaluation as Inhibitors of Insulin-Like Growth Factor Receptor

Anderson, Marc O., Yu, Hong, Penaranda, Cristina, Maddux, Betty A., Goldfine, Ira D., Youngren, Jack F., Guy, R. Kiplin

Journal:

Journal of Combinatorial Chemistry

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

28

The Molecular Basis for Oxidative Stress-Induced Insulin Resistance

Evans, Joseph L., Maddux, Betty A., Goldfine, Ira D.

Journal:

Antioxidants & Redox Signaling

Year:

2005

Language:

english

File:

PDF, 327 KB

english, 2005

29

The Development of Insulin Resistance with High Fat Feeding in Rats Does Not Involve Either Decreased Insulin Receptor Tyrosine Kinase Activity or Membrane Glycoprotein PC-1

Begüm Özel, Jack F. Youngren, Jason K. Kim, Ira D. Goldfine, Chin K. Sung, Jang H. Youn

Journal:

Biochemical and Molecular Medicine

Year:

1996

Language:

english

File:

PDF, 144 KB

english, 1996

30

Rodent Insulin Receptors Are Immunologically Different from Other Mammalian Insulin Receptors

Zhi.-Qiang Tong, Elaine Jack, Margaret Moule, Ira D. Goldfine, Cecil C. Yip

Journal:

General and Comparative Endocrinology

Year:

1994

File:

PDF, 370 KB

1994

31

Proglumide (gastrin and cholecystokinin receptor antagonist) inhibits insulin secretion in vitro

Eugen J. Verspohl, Gabriele Wunderle, Hermann P. T. Ammon, John A. Williams, Ira D. Goldfine

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1986

Language:

english

File:

PDF, 446 KB

english, 1986

32

Interaction of insulin, polypeptide hormones, and growth factors with intracellular membranes

Ira D. Goldfine

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes

Year:

1981

Language:

english

File:

PDF, 1.38 MB

english, 1981

33

Unraveling the riddle of insulin resistance

Journal:

Journal of Laboratory and Clinical Medicine

Year:

1999

Language:

english

File:

PDF, 232 KB

english, 1999

34

The interaction of radioiodinated thyrotropin with plasma membranes: Evidence for high affinity binding sites in the thyroid

Ira D. Goldfine, Syed M. Amir, Sidney H. Ingbar, Georgianne Tucker

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1976

Language:

english

File:

PDF, 581 KB

english, 1976

35

Regulation of insulin receptor kinase activity by insulin mimickers and an insulin antagonist

Richard A. Roth, Delanie J. Cassell, Betty A. Maddux, Ira D. Goldfine

Journal:

Biochemical and Biophysical Research Communications

Year:

1983

Language:

english

File:

PDF, 1.39 MB

english, 1983

36

Pancreatic CCK receptors: Characterization of covalently labeled subunits

Choitsu Sakamoto, Ira D. Goldfine, John A. Williams

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 1.15 MB

english, 1984

37

Brain CCK receptors are structurally distinct from pancreas CCK receptors

Choitsu Sakamoto, John A. Williams, Ira D. Goldfine

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 1.02 MB

english, 1984

38

Cholecystokinin and insulin regulate insulin-like growth factor II binding to pancreatic receptors; Evidence of a role for intracellular calcium

Neus Potau, Joachim Mössner, John A. Williams, Ira D. Goldfine

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 389 KB

english, 1984

39

Reversal of insulin-induced negative cooperativity by monoclonal antibodies that stabilize the slowly dissociating (“Ksuper”) state of the insulin receptor

Jia-Li Gu, Ira D. Goldfine, John R. Forsayeth, Pierre De Meyts

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 575 KB

english, 1988

40

Heterogeneity of human liver, muscle, and adipose tissue insulin receptor

JoséF. Caro, S.M. Raju, Madhur K. Sinha, Ira D. Goldfine, G.Lynis Dohm

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 637 KB

english, 1988

41

Monoclonal antibodies to the human insulin receptor mimic a spectrum of biological effects in transfected 3T3HIR fibroblasts without activating receptor kinase

Antonio Brunetti, Betty A. Maddux, K.Y. Wong, Cecilia Hofmann, Jonathan Whittaker, Chin Sung, Ira D. Goldfine

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 436 KB

english, 1989

42

Transmembrane signalling by insulin via an insulin receptor mutated at tyrosines 1158, 1162, and 1163

Ronit Rafaeloff, Betty A. Maddux, Antonio Brunetti, Paolo Sbraccia, Chin K. Sung, Robit Patel, Dennis M. Hawley, Ira D. Goldfine

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 591 KB

english, 1991

43

Phosphatidylinositol-3-kinase is a non-tyrosine phosphorylated member of the insulin receptor signalling complex

Chin K. Sung, Ira D. Goldfine

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 529 KB

english, 1992

44

Binding of mutant insulins to a mutated insulin receptor

Ronit Rafaeloff, Cecil C. Yip, Ira D. Goldfine

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 354 KB

english, 1992

45

The CCK receptor on pancreatic plasma membranes: binding characteristics and covalent cross-linking

Choitsu Sakamoto, John A. Williams, K.Y. Wong, Goldfine Ira D.

Journal:

Year:

1983

Language:

english

File:

PDF, 374 KB

english, 1983

46

Radioimmunoassay for human insulin-like growth factor-I receptor: Applicability to breast carcinoma specimens and cell lines

Vincenzo Pezzino, Giovanni Milazzo, Lucia Frittitta, Riccardo Vigneri, Osamu Ezaki, Michihiro Kasahara, Thomas R. LeBon, Ira D. Goldfine, Yoko Fujita-Yamaguchi

Journal:

Year:

1991

Language:

english

File:

PDF, 632 KB

english, 1991

47

Growth factor receptor regulation in the Minn-1 leprechaun: Defects in both insulin receptor and epidermal growth factor receptor gene expression

Patricia A. Goodman, Paolo Sbraccia, Antonio Brunetti, Kwok-Ying Wong, Jacqueline D. Carter, Stephen M. Rosenthal, Ira D. Goldfine

Journal:

Year:

1992

Language:

english

File:

PDF, 659 KB

english, 1992

48

Analysis of insulin-stimulated insulin receptor activation and glucose transport in cultured skeletal muscle cells from obese subjects

Celia Pender, Ira D. Goldfine, Jennifer L. Kulp, Charles J. Tanner, Betty A. Maddux, Kenneth G. MacDonald, Joseph A. Houmard, Jack F. Youngren

Journal:

Year:

2005

Language:

english

File:

PDF, 149 KB

english, 2005

49

Effective treatments for insulin resistance: trim the fat and douse the fire

Joseph L. Evans, Jack F. Youngren, Ira D. Goldfine

Journal:

Trends in Endocrinology & Metabolism

Year:

2004

Language:

english

File:

PDF, 246 KB

english, 2004

50

Expression of insulin-like growth factor-1 receptor in local and metastatic prostate cancer

Charles J. Ryan, Christopher M. Haqq, Jeffrey Simko, Daisuke F. Nonaka, June M. Chan, Vivian Weinberg, Eric J. Small, Ira D. Goldfine

Journal:

Urologic Oncology: Seminars and Original Investigations

Year:

2007

Language:

english

File:

PDF, 2.51 MB

english, 2007