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101

Innate immunity in Alzheimer's disease

Heneka, Michael T, Golenbock, Douglas T, Latz, Eicke

Journal:

Nature Immunology

Year:

2015

Language:

english

File:

PDF, 2.32 MB

english, 2015

102

A Novel Synthetic Acyclic Lipid A-like Agonist Activates Cells via the Lipopolysaccharide/Toll-like Receptor 4 Signaling Pathway

Lien, E., Chow, J. C., Hawkins, L. D., McGuinness, P. D., Miyake, K., Espevik, T., Gusovsky, F., Golenbock, D. T.

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 840 KB

english, 2001

103

Trypsin-Sensitive Modulation of Intestinal Epithelial MD-2 as Mechanism of Lipopolysaccharide Tolerance

Cario, E., Golenbock, D. T., Visintin, A., Runzi, M., Gerken, G., Podolsky, D. K.

Journal:

The Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 974 KB

english, 2006

104

Trif-related adapter molecule is phosphorylated by PKC during Toll-like receptor 4 signaling

McGettrick, A. F., Brint, E. K., Palsson-McDermott, E. M., Rowe, D. C., Golenbock, D. T., Gay, N. J., Fitzgerald, K. A., O'Neill, L. A. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 993 KB

english, 2006

105

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9

Parroche, P., Lauw, F. N., Goutagny, N., Latz, E., Monks, B. G., Visintin, A., Halmen, K. A., Lamphier, M., Olivier, M., Bartholomeu, D. C., Gazzinelli, R. T., Golenbock, D. T.

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 323 KB

english, 2007

106

UNC93B1 and Nucleic Acid-sensing Toll-like Receptors Mediate Host Resistance to Infection with Leishmania major

Schamber-Reis, B. L. F., Petritus, P. M., Caetano, B. C., Martinez, E. R., Okuda, K., Golenbock, D., Scott, P., Gazzinelli, R. T.

Journal:

Journal of Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 3.35 MB

english, 2013

107

Lipoproteins Are Critical TLR2 Activating Toxins in Group B Streptococcal Sepsis

Henneke, P., Dramsi, S., Mancuso, G., Chraibi, K., Pellegrini, E., Theilacker, C., Hubner, J., Santos-Sierra, S., Teti, G., Golenbock, D. T., Poyart, C., Trieu-Cuot, P.

Journal:

The Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 887 KB

english, 2008

108

Cellular Activation, Phagocytosis, and Bactericidal Activity Against Group B Streptococcus Involve Parallel Myeloid Differentiation Factor 88-Dependent and Independent Signaling Pathways

Henneke, P., Takeuchi, O., Malley, R., Lien, E., Ingalls, R. R., Freeman, M. W., Mayadas, T., Nizet, V., Akira, S., Kasper, D. L., Golenbock, D. T.

Journal:

The Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 310 KB

english, 2002

109

Activation of the NLRP3 Inflammasome by Group B Streptococci

Costa, A., Gupta, R., Signorino, G., Malara, A., Cardile, F., Biondo, C., Midiri, A., Galbo, R., Trieu-Cuot, P., Papasergi, S., Teti, G., Henneke, P., Mancuso, G., Golenbock, D. T., Beninati, C.

Journal:

The Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 761 KB

english, 2012

110

MD-2 Residues Tyrosine 42, Arginine 69, Aspartic Acid 122, and Leucine 125 Provide Species Specificity for Lipid IVA

Meng, J., Drolet, J. R., Monks, B. G., Golenbock, D. T.

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 2.74 MB

english, 2010

111

Dual Role of TLR2 and Myeloid Differentiation Factor 88 in a Mouse Model of Invasive Group B Streptococcal Disease

Mancuso, G., Midiri, A., Beninati, C., Biondo, C., Galbo, R., Akira, S., Henneke, P., Golenbock, D., Teti, G.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 176 KB

english, 2004

112

Toll-Like Receptor 4 Mediates Intracellular Signaling Without TNF- Release in Response to Cryptococcus neoformans Polysaccharide Capsule

Shoham, S., Huang, C., Chen, J.-M., Golenbock, D. T., Levitz, S. M.

Journal:

The Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 1.25 MB

english, 2001

113

Differential Effects of a Toll-Like Receptor Antagonist on Mycobacterium tuberculosis-Induced Macrophage Responses

Means, T. K., Jones, B. W., Schromm, A. B., Shurtleff, B. A., Smith, J. A., Keane, J., Golenbock, D. T., Vogel, S. N., Fenton, M. J.

Journal:

The Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 576 KB

english, 2001

114

Divergent Response to LPS and Bacteria in CD14-Deficient Murine Macrophages

Moore, K. J., Andersson, L. P., Ingalls, R. R., Monks, B. G., Li, R., Arnaout, M. A., Golenbock, D. T., Freeman, M. W.

Journal:

The Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 416 KB

english, 2000

115

Recognition of Hyaluronan Released in Sterile Injury Involves a Unique Receptor Complex Dependent on Toll-like Receptor 4, CD44, and MD-2

Taylor, K. R., Yamasaki, K., Radek, K. A., Nardo, A. D., Goodarzi, H., Golenbock, D., Beutler, B., Gallo, R. L.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 968 KB

english, 2007

116

Lipoproteins are critical TLR2 activating toxins in group B streptococcal sepsis

Henneke, P., Dramsi, S., Mancuso, G., Chraibi, K., Pellegrini, E., Theilacker, C., Hubner, J., Santos-Sierra, S., Teti, G., Golenbock, D. T., Poyart, C., Trieu-Cuot, P.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 217 KB

english, 2009

117

Malaria primes the innate immune response due to interferon- induced enhancement of toll-like receptor expression and function

Franklin, B. S., Parroche, P., Ataide, M. A., Lauw, F., Ropert, C., de Oliveira, R. B., Pereira, D., Tada, M. S., Nogueira, P., da Silva, L. H. P., Bjorkbacka, H., Golenbock, D. T., Gazzinelli, R. T.

Journal:

Proceedings of the National Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 613 KB

english, 2009

118

Membrane Expression of Soluble Endotoxin-binding Proteins Permits Lipopolysaccharide Signaling in Chinese Hamster Ovary Fibroblasts Independently of CD14

Ingalls, R. R., Monks, B. G., Golenbock, D. T.

Journal:

Journal of Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 649 KB

english, 1999

119

Innate Immune Responses to Rhodococcus equi

Darrah, P. A., Monaco, M. C. G., Jain, S., Hondalus, M. K., Golenbock, D. T., Mosser, D. M.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 812 KB

english, 2004

120

Activation of TLR2 and TLR4 by Glycosylphosphatidylinositols Derived from Toxoplasma gondii

Debierre-Grockiego, F., Campos, M. A., Azzouz, N., Schmidt, J., Bieker, U., Resende, M. G., Mansur, D. S., Weingart, R., Schmidt, R. R., Golenbock, D. T., Gazzinelli, R. T., Schwarz, R. T.

Journal:

The Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 1.03 MB

english, 2007

121

Membrane-Associated Proteins of a Lipopolysaccharide-Deficient Mutant of Neisseria meningitidis Activate the Inflammatory Response through Toll-Like Receptor 2

Ingalls, R. R., Lien, E., Golenbock, D. T.

Journal:

Infection and Immunity

Year:

2001

Language:

english

File:

PDF, 284 KB

english, 2001

122

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

McWhirter, S. M., Fitzgerald, K. A., Rosains, J., Rowe, D. C., Golenbock, D. T., Maniatis, T.

Journal:

Proceedings of the National Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 468 KB

english, 2004

123

Cutting Edge: Immune Stimulation by Neisserial Porins Is Toll-Like Receptor 2 and MyD88 Dependent

Massari, P., Henneke, P., Ho, Y., Latz, E., Golenbock, D. T., Wetzler, L. M.

Journal:

The Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 661 KB

english, 2002

124

The Role of Lipopolysaccharide Binding Protein in Resistance to Salmonella Infections in Mice

Fierer, J., Swancutt, M. A., Heumann, D., Golenbock, D.

Journal:

The Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 329 KB

english, 2002

125

IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients

Sandanger, O., Ryan, L., Bohnhorst, J., Iversen, A.-C., Husebye, H., Halaas, O., Landro, L., Aukrust, P., Froland, S. S., Elson, G., Visintin, A., Oktedalen, O., Damas, J. K., Sundan, A., Golenbock, D

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 1010 KB

english, 2009

126

NO Is a Macrophage Autonomous Modifier of the Cytokine Response to Streptococcal Single-Stranded RNA

Deshmukh, S. D., Muller, S., Hese, K., Rauch, K. S., Wennekamp, J., Takeuchi, O., Akira, S., Golenbock, D. T., Henneke, P.

Journal:

The Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 605 KB

english, 2012

127

Lipopolysaccharide Rapidly Traffics to and from the Golgi Apparatus with the Toll-like Receptor 4-MD-2-CD14 Complex in a Process That Is Distinct from the Initiation of Signal Transduction

Latz, E., Visintin, A., Lien, E., Fitzgerald, K. A., Monks, B. G., Kurt-Jones, E. A., Golenbock, D. T., Espevik, T.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 1.01 MB

english, 2002

128

Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line: A Point Mutation in a Conserved Region of Md-2 Abolishes Endotoxin-Induced Signaling

Schromm, A. B., Lien, E., Henneke, P., Chow, J. C., Yoshimura, A., Heine, H., Latz, E., Monks, B. G., Schwartz, D. A., Miyake, K., Golenbock, D. T.

Journal:

Journal of Experimental Medicine

Year:

2001

Language:

english

File:

PDF, 267 KB

english, 2001

129

Mechanisms of TLR9 activation

Latz, E., Visintin, A., Espevik, T., Golenbock, D. T.

Journal:

Journal of Endotoxin Research

Year:

2004

Language:

english

File:

PDF, 539 KB

english, 2004

130

Toll-like Receptor (TLR) Signaling in Response toAspergillus fumigatus

Mambula, S. S., Sau, K., Henneke, P., Golenbock, D. T., Levitz, S. M.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 680 KB

english, 2002

131

A TIR Domain Variant of MyD88 Adapter-like (Mal)/TIRAP Results in Loss of MyD88 Binding and Reduced TLR2/TLR4 Signaling

Nagpal, K., Plantinga, T. S., Wong, J., Monks, B. G., Gay, N. J., Netea, M. G., Fitzgerald, K. A., Golenbock, D. T.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 1.98 MB

english, 2009

132

Chlamydia pneumoniae and Chlamydial Heat Shock Protein 60 Stimulate Proliferation of Human Vascular Smooth Muscle Cells via Toll-Like Receptor 4 and p44/p42 Mitogen-Activated Protein Kinase Activation

Sasu, S., LaVerda, D., Qureshi, N., Golenbock, D. T., Beasley, D.

Journal:

Circulation Research

Year:

2001

Language:

english

File:

PDF, 1.09 MB

english, 2001

133

Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin

Corbett, Yolanda, Parapini, Silvia, D'Alessandro, Sarah, Scaccabarozzi, Diletta, Rocha, Bruno C., Egan, Timothy J., Omar, Aneesa, Galastri, Laura, Fitzgerald, Katherine A., Golenbock, Douglas T., Tara

Journal:

Microbes and Infection

Year:

2015

Language:

english

File:

PDF, 1.43 MB

english, 2015

134

Dysregulation of LPS-Induced Toll-Like Receptor 4-MyD88 Complex Formation and IL-1 Receptor-Associated Kinase 1 Activation in Endotoxin-Tolerant Cells

Medvedev, A. E., Lentschat, A., Wahl, L. M., Golenbock, D. T., Vogel, S. N.

Journal:

The Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 388 KB

english, 2002

135

Biological Activities of Bacteroides forsythus Lipoproteins and Their Possible Pathological Roles in Periodontal Disease

Hasebe, A., Yoshimura, A., Into, T., Kataoka, H., Tanaka, S., Arakawa, S., Ishikura, H., Golenbock, D. T., Sugaya, T., Tsuchida, N., Kawanami, M., Hara, Y., Shibata, K.-i.

Journal:

Infection and Immunity

Year:

2004

Language:

english

File:

PDF, 337 KB

english, 2004

136

c-Jun Kinase Is a Critical Signaling Molecule in a Neonatal Model of Group B Streptococcal Sepsis

Kenzel, S., Mancuso, G., Malley, R., Teti, G., Golenbock, D. T., Henneke, P.

Journal:

The Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 798 KB

english, 2006

137

Activation of Toll-Like Receptor (TLR)2, TLR4, and TLR9 in the Mammalian Cornea Induces MyD88-Dependent Corneal Inflammation

Johnson, Angela C., Heinzel, Fred P., Diaconu, Eugenia, Sun, Yan, Hise, Amy G., Golenbock, Douglas, Lass, Jonathan H., Pearlman, Eric

Journal:

Investigative Ophthalmology & Visual Science

Year:

2005

Language:

english

File:

PDF, 248 KB

english, 2005

138

Identification of CD18 as a novel Taxol binding/signaling protein in murine macrophage membranes

Vogel, S. N., Bhat, N., Carboni, J. M., Mayadas, T. N., Blanco, J., Perera, P.-Y., Golenbock, D. T.

Journal:

Journal of Endotoxin Research

Year:

1999

Language:

english

File:

PDF, 81 KB

english, 1999

139

Recombinant Ov-ASP-1, a Th1-Biased Protein Adjuvant Derived from the Helminth Onchocerca volvulus, Can Directly Bind and Activate Antigen-Presenting Cells

He, Y., Barker, S. J., MacDonald, A. J., Yu, Y., Cao, L., Li, J., Parhar, R., Heck, S., Hartmann, S., Golenbock, D. T., Jiang, S., Libri, N. A., Semper, A. E., Rosenberg, W. M., Lustigman, S.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 947 KB

english, 2009

140

The Differential Impact of Disulfide Bonds and N-Linked Glycosylation on the Stability and Function of CD14

Meng, J., Parroche, P., Golenbock, D. T., McKnight, C. J.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 924 KB

english, 2008

141

IMMUNOLOGY: The Shape of Things to Come

Fitzgerald, K. A., Golenbock, D. T.

Journal:

Year:

2007

Language:

english

File:

PDF, 403 KB

english, 2007

142

Natural Loss-of-function Mutation of Myeloid Differentiation Protein 88 Disrupts Its Ability to Form Myddosomes

Nagpal, K., Plantinga, T. S., Sirois, C. M., Monks, B. G., Latz, E., Netea, M. G., Golenbock, D. T.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.34 MB

english, 2011

143

MyD88-Dependent Pathways Mediate Resistance to Cryptosporidium parvum Infection in Mice

Rogers, K. A., Rogers, A. B., Leav, B. A., Sanchez, A., Vannier, E., Uematsu, S., Akira, S., Golenbock, D., Ward, H. D.

Journal:

Infection and Immunity

Year:

2006

Language:

english

File:

PDF, 522 KB

english, 2006

144

Haemophilus influenzae Type b-Outer Membrane Protein Complex Glycoconjugate Vaccine Induces Cytokine Production by Engaging Human Toll-Like Receptor 2 (TLR2) and Requires the Presence of TLR2 for Optimal Immunogenicity

Latz, E., Franko, J., Golenbock, D. T., Schreiber, J. R.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 581 KB

english, 2004

145

The LPS receptor generates inflammatory signals from the cell surface

Latz, E., Visintin, A., Lien, E., Fitzgerald, K. A., Espevik, T., Golenbock, D. T.

Journal:

Journal of Endotoxin Research

Year:

2003

Language:

english

File:

PDF, 297 KB

english, 2003

146

Surface presentation of LPS is sufficient for initiation of signaling events

Ingalls, R. R., Monks, B. G., Golenbock, D. T.

Journal:

Journal of Endotoxin Research

Year:

1999

Language:

english

File:

PDF, 81 KB

english, 1999

147

Neutrophil Influx in Response to a Peritoneal Infection with Salmonella Is Delayed in Lipopolysaccharide-Binding Protein or CD14-Deficient Mice

Yang, K. K., Dorner, B. G., Merkel, U., Ryffel, B., Schutt, C., Golenbock, D., Freeman, M. W., Jack, R. S.

Journal:

The Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 468 KB

english, 2002

148

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction

Rowe, D. C., McGettrick, A. F., Latz, E., Monks, B. G., Gay, N. J., Yamamoto, M., Akira, S., O'Neill, L. A., Fitzgerald, K. A., Golenbock, D. T.

Journal:

Proceedings of the National Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 893 KB

english, 2006

149

Toll-Like Receptor 2-Dependent Inhibition of Macrophage Class II MHC Expression and Antigen Processing by 19-kDa Lipoprotein of Mycobacterium tuberculosis

Noss, E. H., Pai, R. K., Sellati, T. J., Radolf, J. D., Belisle, J., Golenbock, D. T., Boom, W. H., Harding, C. V.

Journal:

The Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 1.02 MB

english, 2001

150

Cell activation by Toll-like receptors: role of LBP and CD14

Finberg, R. W., Re, F., Popova, L., Golenbock, D. T., Kurt-Jones, E. A.

Journal:

Journal of Endotoxin Research

Year:

2004

Language:

english

File:

PDF, 230 KB

english, 2004