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1

A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo

Fueyo, Juan, Gomez-Manzano, Candelaria, Alemany, Ramon, Lee, Polly SY, McDonnell, Timothy J, Mitlianga, Paraskevi, Shi, Yue-Xi, Levin, V A, Yung, W K Alfred, Kyritsis, Athanassios P

Journal:

Year:

2000

Language:

english

File:

PDF, 649 KB

english, 2000

2

Oncolytic adenovirus and tumor-targeting immune modulatory therapy improve autologous cancer vaccination

Jiang, Hong, Rivera-Molina, Yisel, Clise-Dwyer, Karen, Bover, Laura, Vence, Luis, Yuan, Ying, Lang, Frederick F., Toniatti, Carlo, Hossain, Mohammad B., Gomez-Manzano, Candelaria, Fueyo, Juan

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 5.56 MB

english, 2017

3

TMOD-17. A NOVEL ADENOVIRAL-PERMISSIVE, IMMUNOCOMPETENT HAMSTER MODEL TO EVALUATE ONCOLYTIC ADENOVIRAL THERAPY FOR GLIOBLASTOMA

Phillips, Lynette, Li, Shoudong, Gumin, Joy, Ledbetter, Daniel, Hossain, Anwar, Kerrigan, Brittany, Gomez-Manzano, Candelaria, Fueyo, Juan, Lang, Frederick

Journal:

Year:

2018

Language:

english

File:

PDF, 91 KB

english, 2018

4

TMOD-17. A NOVEL ADENOVIRAL-PERMISSIVE, IMMUNOCOMPETENT HAMSTER MODEL TO EVALUATE ONCOLYTIC ADENOVIRAL THERAPY FOR GLIOBLASTOMA

Phillips, Lynette, Li, Shoudong, Gumin, Joy, Ledbetter, Daniel, Hossain, Anwar, Kerrigan, Brittany, Gomez-Manzano, Candelaria, Fueyo, Juan, Lang, Frederick

Journal:

Year:

2018

File:

PDF, 91 KB

2018

5

Mechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesis

Candelaria Gomez-Manzano, Juan Fueyo, Hong Jiang, Tricia L. Glass, Ho-Young Lee, Min Hu, Juinn-Lin Liu, Sushma L. Jasti, Ta-Jen Liu, Charles A. Conrad, W. K. Alfred Yung

Journal:

Annals of Neurology

Year:

2003

Language:

english

File:

PDF, 337 KB

english, 2003

6

Cytotoxicity of VEGF121/rGel on vascular endothelial cells resulting in inhibition of angiogenesis is mediated via VEGFR-2

Khalid A Mohamedali, Sophia Ran, Candelaria Gomez-Manzano, Latha Ramdas, Jing Xu, Sehoon Kim, Lawrence H Cheung, Walter N Hittelman, Wei Zhang, Johannes Waltenberger, Philip E Thorpe, Michael G Rosenb

Journal:

Year:

2011

Language:

english

File:

PDF, 502 KB

english, 2011

7

Robust infectivity and replication of Delta-24 adenovirus induce cell death in human medulloblastoma

Stolarek, Robert, Gomez-Manzano, Candelaria, Jiang, Hong, Suttle, Gary, Lemoine, Michael G, Fueyo, Juan

Journal:

Cancer Gene Therapy

Year:

2004

Language:

english

File:

PDF, 261 KB

english, 2004

8

Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro

Chintala, Shravan K, Fueyo, Juan, Gomez-Manzano, Candelaria, Venkaiah, Boyapati, Bjerkvig, Rolf, Yung, WK Alfred, Sawaya, Raymond, Kyritsis, Athanassios P, Rao, Jasti S

Journal:

Year:

1997

Language:

english

File:

PDF, 648 KB

english, 1997

9

Corrigendum

Fueyo, Juàn, Gomez-Manzano, Candelaria, Alemany, Ramon, Lee, Polly SN, McDonnell, Timothy J, Mitlianga, Paraskevi, Shi, Yue-Xi, Levin, V A, Yung, WK Alfred, Kyritsis, Athanassios P

Journal:

Year:

2000

Language:

english

File:

PDF, 134 KB

english, 2000

10

A novel E1A–E1B mutant adenovirus induces glioma regression in vivo

Gomez-Manzano, Candelaria, Balague, Cristina, Alemany, Ramon, Lemoine, Michael G, Mitlianga, Paraskevi, Jiang, Hong, Khan, Asadullah, Alonso, Marta, Lang, Frederick F, Conrad, Charles A

Journal:

Year:

2004

Language:

english

File:

PDF, 359 KB

english, 2004

11

Gene Therapy for Gliomas: Molecular Targets, Adenoviral Vectors, and Oncolytic Adenoviruses

Ramon Alemany, Candelaria Gomez-Manzano, Cristina Balagué, W.K. Alfred Yung, David T. Curiel, Athanassios P. Kyritsis, Juan Fueyo

Journal:

Experimental Cell Research

Year:

1999

Language:

english

File:

PDF, 95 KB

english, 1999

12

E2F1 in gliomas: A paradigm of oncogene addiction

Marta M. Alonso, Ramon Alemany, Juan Fueyo, Candelaria Gomez-Manzano

Journal:

Year:

2008

Language:

english

File:

PDF, 193 KB

english, 2008

13

Comparative Effect of Oncolytic Adenoviruses with E1 A or E113-55 kDa Deletions in Malignant Gliomas

Jiang, Hong, Gomez-Manzano, Candelaria, Alemany, Ramon, Medrano, Diana, Alonso, Marta, Bekele, B. Nebiyou, Lin, E, Conrad, Charles C., Yung, W.K. Alfred, Fueyo, Juan

Journal:

Year:

2005

Language:

english

File:

PDF, 344 KB

english, 2005

14

Downmodulation of El A Protein Expression as a Novel Strategy to Design Cancer-Selective Adenoviruses

Jiang, Hong, Alemany, Ramon, Gomez-Manzano, Candelaria, Medrano, Diana R., Lemoine, Michael G., Olson, Melissa V., Alonso, Marta M., Lee, Ok-Hee, Conrad, Charles C., Yung, W.K. Alfred, Fueyo, Juan

Journal:

Year:

2005

Language:

english

File:

PDF, 438 KB

english, 2005

15

Delta-24-RGD in Combination With RAD001 Induces Enhanced Anti-glioma Effect via Autophagic Cell Death

Alonso, Marta M, Jiang, Hong, Yokoyama, Tomohisa, Xu, Jing, Bekele, Nebiyou B, Lang, Frederick F, Kondo, Seiji, Gomez-Manzano, Candelaria, Fueyo, Juan

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 380 KB

english, 2008

16

Oncolytic viruses and DNA-repair machinery: overcoming chemoresistance of gliomas

Jiang, Hong, Alonso, Marta M, Gomez-Manzano, Candelaria, Piao, Yuji, Fueyo, Juan

Journal:

Expert Review of Anticancer Therapy

Year:

2006

Language:

english

File:

PDF, 178 KB

english, 2006

17

Oncolytic adenoviruses as antiglioma agents

Jiang, Hong, McCormick, Frank, Lang, Frederick F, Gomez-Manzano, Candelaria, Fueyo, Juan

Journal:

Expert Review of Anticancer Therapy

Year:

2006

Language:

english

File:

PDF, 1.10 MB

english, 2006

18

320. Modeling Human Brain Cancer in Transgenic E2F1 Mice

Olson, Melissa V., Aldape, Kenneth D., Fuller, Gregory N., Alonso, Marta M., Gomez-Manzano, Candelaria, David, Johnson G., Juan, Fueyo

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

19

Oncolytic adenovirus research evolution: from cell-cycle checkpoints to immune checkpoints

Jiang, Hong, Gomez-Manzano, Candelaria, Rivera-Molina, Yisel, Lang, Frederick F, Conrad, Charles A, Fueyo, Juan

Journal:

Current Opinion in Virology

Year:

2015

Language:

english

File:

PDF, 1015 KB

english, 2015

20

[Handbook of Clinical Neurology] Neuro-Oncology. Vol 104 HCN Series Volume 104 || Gene therapy

Gomez-Manzano, Candelaria

Year:

2012

Language:

english

File:

PDF, 423 KB

english, 2012

21

Macrophage Ablation Reduces M2-Like Populations and Jeopardizes Tumor Growth in a MAFIA-Based Glioma Model

Gabrusiewicz, Konrad, Hossain, Mohammad B., Cortes-Santiago, Nahir, Fan, Xuejun, Kaminska, Bozena, Marini, Frank C., Fueyo, Juan, Gomez-Manzano, Candelaria

Journal:

Year:

2015

Language:

english

File:

PDF, 2.37 MB

english, 2015

22

Adenovirus’s last trick: You say lysis, we say autophagy

Jiang, Hong, White, Erin J., Gomez-Manzano, Candelaria, Fueyo-Margareto, Juan

Journal:

Year:

2008

Language:

english

File:

PDF, 328 KB

english, 2008

23

Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU

Gomez-Manzano, Candelaria, Lemoine, Michael, Hu, Min, He, Ju, Mitlianga, Paraskevi, Liu, Ta-Jen, Yung, Alfred, Fueyo, Juan, Groves, Morris

Journal:

International Journal of Oncology

Year:

2001

Language:

english

File:

PDF, 1.81 MB

english, 2001

24

Overexpression of E2F-1 leads to bax-independent cell death in human glioma cells

Mitlianga, Paraskevi, Gomez-Manzano, Candelaria, Kyritsis, Athanassios, Fueyo, Juan

Journal:

International Journal of Oncology

Year:

2002

Language:

english

File:

PDF, 1.55 MB

english, 2002

25

Adenovirus, autophagy and lysis: ecstasies and agonies

Balvers, Rutger, Jiang, Hong, Piya, Sujan, Gomez-Manzano, Candelaria, Fueyo, Juan

Journal:

Future Virology

Year:

2011

Language:

english

File:

PDF, 293 KB

english, 2011

26

Delta-24-RGD Induces Cytotoxicity of Glioblastoma Spheroids in Three Dimensional PEG Microwells

Avci, Naze G., Fan, Yantao, Dragomir, Andrei, Akay, Yasemin M., Gomez-Manzano, Candelaria, Fueyo-Margareto, Juan, Akay, Metin

Journal:

IEEE Transactions on NanoBioscience

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

27

Interspecies adenovirus fiber shows "evolutionary" advantage for oncolytic therapy of gliomas

Gomez-Manzano, Candelaria, Alonso, Marta, Jiang, Hong, Fueyo, Juan

Journal:

Cancer Biology & Therapy

Year:

2008

Language:

english

File:

PDF, 802 KB

english, 2008

28

E2F1 and Telomerase: Alliance in the Dark Side

Alonso, Marta M., Fueyo-Margareto, Juan, Yung, W.K. Alfred, Gomez-Manzano, Candelaria

Journal:

Year:

2006

Language:

english

File:

PDF, 323 KB

english, 2006

29

RB-E2F1

Jiang, Hong, Martin, Vanesa, Alonso, Marta, Gomez-Manzano, Candelaria, Fueyo-Margareto, Juan

Journal:

Year:

2010

Language:

english

File:

PDF, 679 KB

english, 2010

30

IMPS-09COMBINATION OF DELTA-24-RGDOX AND ANTI-PDL1 ANTIBODIES INDUCES ANTI-TUMOR EFFECT AND ANTI-GLIOMA IMMUNE MEMORY

Jiang, Hong, Gomez-Manzano, Candelaria, Lang, Frederick, Tufaro, Frank, Yung, W.K. Alfred, Sawaya, Raymond, Fueyo, Juan

Journal:

Year:

2015

Language:

english

File:

PDF, 28 KB

english, 2015

31

Encountering and Advancing Through Antiangiogenesis Therapy for Gliomas

Martin, Vanesa, Liu, Dan, Gomez-Manzano, Candelaria

Journal:

Current Pharmaceutical Design

Year:

2009

Language:

english

File:

PDF, 318 KB

english, 2009

32

Advances in Translational Research in Neuro-oncology

Fueyo, Juan, Gomez-Manzano, Candelaria, Yung, W. K. Alfred

Journal:

Archives of Neurology

Year:

2011

Language:

english

File:

PDF, 477 KB

english, 2011

33

Tumor-associated stromal cells as key contributors to the tumor microenvironment

Bussard, Karen M., Mutkus, Lysette, Stumpf, Kristina, Gomez-Manzano, Candelaria, Marini, Frank C.

Journal:

Breast Cancer Research

Year:

2016

Language:

english

File:

PDF, 705 KB

english, 2016

34

Targeting in Gene Therapy for Gliomas

Fueyo, Juan, Gomez-Manzano, Candelaria, Yung, W. K. Alfred, Kyritsis, Athanassios P.

Journal:

Archives of Neurology

Year:

1999

Language:

english

File:

PDF, 141 KB

english, 1999

35

Phase I Trial of DNX-2401 for Diffuse Intrinsic Pontine Glioma Newly Diagnosed in Pediatric Patients

Tejada, Sonia, Alonso, Marta, Patiño, Ana, Fueyo, Juan, Gomez-Manzano, Candelaria, Diez-Valle, Ricardo

Journal:

Year:

2017

Language:

english

File:

PDF, 308 KB

english, 2017

36

PDTM-12. THE ONCOLYTIC ADENOVIRUS DELTA-24-RGD MEDIATES AN EFFICIENT ANTITUMOR RESPONSE IN VIVO IN SUPRATENTORIAL PRIMITIVE NEUROECTODERMAL TUMORS

Garcia-Moure, Marc, Martínez-Vélez, Naiara, González-Huarriz, Marisol, Puigdelloses, Monsterrat, Idoate, Miguel Angel, Valle, Ricardo Diez, Tejada, Sonia, Gomez-manzano, Candelaria, Fueyo, Juan, Patiñ

Journal:

Year:

2017

Language:

english

File:

PDF, 50 KB

english, 2017

37

Linking inflammation and cancer: the unexpected SYK world

Fueyo, Juan, Alonso, Marta M, Parker Kerrigan, Brittany C, Gomez-Manzano, Candelaria

Journal:

Year:

2018

Language:

english

File:

PDF, 327 KB

english, 2018

38

Potentiation of anti-glioma immunity induced by oncolytic adenovirus Delta-24-RGD through viral expression of immune co-stimulator OX40 ligand

Jiang, Hong, Dwyer, Karen, Bover, Laura, Lang, Frederick, Gomez-Manzano, Candelaria, Fueyo, Juan

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2015

Language:

english

File:

PDF, 210 KB

english, 2015

39

ATIM-08. IMMUNOMARKERS IN THE DNX-2401 (DELTA-24-RGD) ONCOLYTIC VIRUS PHASE I CLINICAL TRIAL

Fueyo, Juan, Gomez-Manzano, Candelaria, Villalobos, Paloma, Rodriguez-Canales, Jaime, Wistuba, Ignacio, Hess, Kenneth R, Alonso, Marta M, Tejada, Sonia, Valle, Ricardo Diez, Ewald, Brett, Tufaro, Fran

Journal:

Year:

2017

Language:

english

File:

PDF, 51 KB

english, 2017

40

Critical Role of Autophagy in the Processing of Adenovirus Capsid-Incorporated Cancer-Specific Antigens

Klein, Sarah R., Jiang, Hong, Hossain, Mohammad B., Fan, Xuejun, Gumin, Joy, Dong, Andrew, Alonso, Marta M., Gomez-Manzano, Candelaria, Fueyo, Juan, Castro, Maria G

Journal:

Year:

2016

Language:

english

File:

PDF, 1.12 MB

english, 2016

41

DIPG-17. ONCOLYTIC VIRUS FOR pHGG AND DIPGs: FROM THE BENCH TO THE BEDSIDE

Tejada, Sonia, Martinez-Velez, Naiara, Varela, Maider, Dominguez, Pablo, Fueyo, Juan, Gomez-Manzano, Candelaria, Aristu, Javier, Diez, Ricardo, Alonso, Marta

Journal:

Year:

2018

Language:

english

File:

PDF, 54 KB

english, 2018

42

Oncolytic Viruses as Therapeutic Tools for Pediatric Brain Tumors

Varela-Guruceaga, Maider, Tejada-Solís, Sonia, García-Moure, Marc, Fueyo, Juan, Gomez-Manzano, Candelaria, Patiño-García, Ana, Alonso, Marta

Journal:

Year:

2018

Language:

english

File:

PDF, 842 KB

english, 2018

43

Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma

Lang, Frederick F., Conrad, Charles, Gomez-Manzano, Candelaria, Yung, W.K. Alfred, Sawaya, Raymond, Weinberg, Jeffrey S., Prabhu, Sujit S., Rao, Ganesh, Fuller, Gregory N., Aldape, Kenneth D., Gumin,

Journal:

Journal of Clinical Oncology

Year:

2018

File:

PDF, 1.81 MB

2018

44

DIPG-04. TRANSLATION OF DNX-2401 FROM THE BENCH TO THE CLINIC FOR PEDIATRIC HIGH GRADE GLIOMAS INCLUDING DIFFUSE INTRINSIC PONTINE GLIOMAS

Martinez-Velez, Naiara, Garcia-Moure, Marc, Laspidea, Virginia, Becher, Oren, Fueyo, Juan, Gomez-Manzano, Candelaria, Patiño, Ana, Diez-Valle, Ricardo, Tejada-Solis, Sonia, Alonso, Marta

Journal:

Year:

2019

Language:

english

File:

PDF, 129 KB

english, 2019

45

Antitumor immune response during glioma virotherapy

Youssef, Gilbert C, Gomez-Manzano, Candelaria, Sawaya, Raymond, Fueyo, Juan

Journal:

Year:

2019

Language:

english

File:

PDF, 154 KB

english, 2019

46

EXTH-30. IN SITU AUTOVACCINATION MEDIATED BY ONCOLYTIC ADENOVIRUS DELTA-24-RGDOX INDUCES EFFICACIOUS IMMUNITY AGAINST METASTATIC MELANOMA

Jiang, Hong, Nguyen, Teresa, Ho Shi, Dong, Fan, Xuejun, Gumin, Joy, Bernatchez, Chantale, Lang, Frederick, Gomez-Manzano, Candelaria, Fueyo, Juan

Journal:

Year:

2018

Language:

english

File:

PDF, 80 KB

english, 2018

47

EXTH-30. IN SITU AUTOVACCINATION MEDIATED BY ONCOLYTIC ADENOVIRUS DELTA-24-RGDOX INDUCES EFFICACIOUS IMMUNITY AGAINST METASTATIC MELANOMA

Jiang, Hong, Nguyen, Teresa, Ho Shi, Dong, Fan, Xuejun, Gumin, Joy, Bernatchez, Chantale, Lang, Frederick, Gomez-Manzano, Candelaria, Fueyo, Juan

Journal:

Year:

2018

File:

PDF, 80 KB

2018

48

PDCT-18 (LTBK-03). PHASE I CLINICAL TRIAL WITH ONCOLYTIC VIRUS DNX-2401 FOR DIPGS

Iñigo-Marco, Ignacio, Díez-Valle, Ricardo, Garcia-Moure, Marc, Patiño-García, Ana, González Huarriz, Marisol, Jones, Chris, Gomez-Manzano, Candelaria, Fueyo, Juan, Alonso, Marta M, Tejada, Sonia

Journal:

Year:

2019

Language:

english

File:

PDF, 156 KB

english, 2019

49

IMMU-14. ONCOLYTIC VIRUS EXPRESSING A POSITIVE IMMUNE CHECKPOINT MODULATOR AS A THERAPEUTIC APPROACH FOR DIPG

Laspidea, Virginia, Puigdelloses, Montse, IÃ±igo-Marco, Ignacio, Garcia-Moure, Marc, Ausejo, Iker, Gallego, Jaime, Fueyo, Juan, Gomez-Manzano, Candelaria, Alonso, Marta M

Journal:

Year:

2019

File:

PDF, 88 KB

2019

50

EXTH-27. ACTIVATING THE IMMUNITY WITHIN THE TUMOR USING VIROIMMUNOTHERAPY: DELTA-24-RGD ONCOLYTIC ADENOVIRUS ARMED WITH THE IMMUNOPOSITIVE REGULATOR GITRL

Rivera-Molina, Yisel, Fueyo, Juan, Jiang, Hong, Nguyen, Teresa, Ho Shin, Dong, Youssef, Gilbert, Fan, Xuejun, Gumin, Joy, Alonso, Marta M, Phadnis, Sheetal, Lang, Frederick, Gomez-Manzano, Candelaria

Journal:

Year:

2019

File:

PDF, 88 KB

2019

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