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51

The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis

Helen Blanchard, Lalitha Kodandapani, Peer RE Mittl, Stefania Di Marco, Joseph F Krebs, Joe C Wu, Kevin J Tomaselli, Markus G Grütter

Journal:

Year:

1999

Language:

english

File:

PDF, 485 KB

english, 1999

52

Electrostatic interactions in the cellular dynamics of the interferon-receptor complex

Gilles UZE, Marie-Thérèse BANDU, Pierre EID, Markus GRÜTTER, Knud E. MOGENSEN

Journal:

Year:

1988

Language:

english

File:

PDF, 1.11 MB

english, 1988

53

Recombinant Soluble β-1,4-Galactosyltransferases Expressed in Saccharomyces cerevisiae : Purification, Characterization and Comparison with Human Enzyme

Martine Malissard, Lubor Borsig, Stefania Di Marco, Markus G. Grütter, Udo Kragl, Christian Wandrey, Eric G. Berger

Journal:

Year:

1996

Language:

english

File:

PDF, 1.10 MB

english, 1996

54

Crystal Structures of BapA Complexes with β-Lactam-Derived Inhibitors Illustrate Substrate Specificity and Enantioselectivity of β-Aminopeptidases

Dr. Tobias Heck, Dr. Tobias Merz, Artur Reimer, Prof. Dr. Dieter Seebach, Dr. Daniel Rentsch, Dr. Christophe Briand, Prof. Dr. Markus G. Grütter, Dr. Hans-Peter E. Kohler, Dr. Birgit Geueke

Journal:

Year:

2012

Language:

english

File:

PDF, 2.43 MB

english, 2012

55

Ligand-Induced Dimerization of the Extracellular Domain of the TGF-β Receptor Type II

Odile Letourneur, Jean-François Goetschy, Michel Horisberger, Markus G. Grütter

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 250 KB

english, 1996

56

In vitro structure-function analysis of the β-strand 326-333 of human p53

Patrick Chène, Peer Mittl, Markus Grütter

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 460 KB

english, 1997

57

Caspase-8 specificity probed at subsite S4:crystal structure of the caspase-8-Z-DEVD-cho complex

Helen Blanchard, Mrudula Donepudi, Markus Tschopp, Lalitha Kodandapani, Joe C Wu, Markus G Grütter

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 386 KB

english, 2000

58

Viral escape at the molecular level explained by quantitative T-cell receptor/peptide/MHC interactions and the crystal structure of a peptide/MHC complex

Alain C Tissot, Carlo Ciatto, Peer R.E Mittl, Markus G Grütter, Andreas Plückthun

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 464 KB

english, 2000

59

Structure of the soluble domain of a membrane-anchored thioredoxin-like protein from Bradyrhizobium japonicum reveals unusual properties

Guido Capitani, Reinhild Rossmann, David F Sargent, Markus G Grütter, Timothy J Richmond, Hauke Hennecke

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 886 KB

english, 2001

60

Zooming in on the hydrophobic ridge of H-2Db: implications for the conformational variability of bound peptides

Carlo Ciatto, Alain C Tissot, Markus Tschopp, Guido Capitani, Frédéric Pecorari, Andreas Plückthun, Markus G Grütter

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 559 KB

english, 2001

61

Crystallization and preliminary X-ray analysis of recombinant human transforming growth factor β2

Michael P. Schlunegger, Nico Cerletti, David A. Cox, Gary K. McMaster, Albert Schmitz, Markus G. Grütter

Journal:

Year:

1992

Language:

english

File:

PDF, 334 KB

english, 1992

62

X-ray crystal structure of the serine proteinase inhibitor eglin c at 1.95 Å resolution

Karsten Hipler, John P. Priestle, Joseph Rahuel, Markus G. Grütter

Journal:

Year:

1992

Language:

english

File:

PDF, 837 KB

english, 1992

63

TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling

Markus G Grütter, Jeremy Luban

Journal:

Current Opinion in Virology

Year:

2012

Language:

english

File:

PDF, 1.58 MB

english, 2012

64

Fire and death: the pyrin domain joins the death-domain superfamily

Andreas Kohl, Markus G. Grütter

Journal:

Comptes Rendus Biologies

Year:

2004

Language:

english

File:

PDF, 500 KB

english, 2004

65

A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels

Thomas Grutter, Lia Prado de Carvalho, Virginie Dufresne, Antoine Taly, Markus Fischer, Jean-Pierre Changeux

Journal:

Comptes Rendus Biologies

Year:

2005

File:

PDF, 486 KB

2005

66

Structure of the PRYSPRY-domain: Implications for autoinflammatory diseases

Christian Grütter, Christophe Briand, Guido Capitani, Peer R.E. Mittl, Stephanie Papin, Jürg Tschopp, Markus G. Grütter

Journal:

Year:

2006

Language:

english

File:

PDF, 1.65 MB

english, 2006

67

The Crystal Structure of Helicobacter Cysteine-rich Protein C at 2.0 Å Resolution: Similar Peptide-binding Sites in TPR and SEL1-like Repeat Proteins

Lucas Lüthy, Markus G Grütter, Peer R.E Mittl

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 587 KB

english, 2004

68

High-resolution Structures of Escherichia coli cDsbD in Different Redox States: A Combined Crystallographic, Biochemical and Computational Study

Christian U. Stirnimann, Anna Rozhkova, Ulla Grauschopf, Rainer A. Böckmann, Rudi Glockshuber, Guido Capitani, Markus G. Grütter

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 1.01 MB

english, 2006

69

Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-ray Structure Analysis

Rajkumar Ganesan, Peer R.E. Mittl, Stjepan Jelakovic, Markus G. Grütter

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 559 KB

english, 2006

70

Stabilizing Ionic Interactions in a Full-consensus Ankyrin Repeat Protein

Tobias Merz, Svava K. Wetzel, Susan Firbank, Andreas Plückthun, Markus G. Grütter, Peer R.E. Mittl

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 799 KB

english, 2008

71

Vacuolar Protein Sorting: Two Different Functional States of the AAA-ATPase Vps4p

Claudia Hartmann, Mohamed Chami, Ulrich Zachariae, Bert L. de Groot, Andreas Engel, Markus G. Grütter

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.67 MB

english, 2008

72

DsbL and DsbI Form a Specific Dithiol Oxidase System for Periplasmic Arylsulfate Sulfotransferase in Uropathogenic Escherichia coli

John P.A. Grimshaw, Christian U. Stirnimann, Maurice S. Brozzo, Goran Malojcic, Markus G. Grütter, Guido Capitani, Rudi Glockshuber

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 2.16 MB

english, 2008

73

Crystal Structure of the Multidrug Exporter MexB from Pseudomonas aeruginosa

Gaby Sennhauser, Magdalena A. Bukowska, Christophe Briand, Markus G. Grütter

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 3.14 MB

english, 2009

74

A Common Structural Basis for pH- and Calmodulin-mediated Regulation in Plant Glutamate Decarboxylase

Heinz Gut, Paola Dominici, Stefania Pilati, Alessandra Astegno, Maxim V. Petoukhov, Dmitri I. Svergun, Markus G. Grütter, Guido Capitani

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 4.20 MB

english, 2009

75

The Crystal Structure of Human Pyrin B30.2 Domain: Implications for Mutations Associated with Familial Mediterranean Fever

Christopher Weinert, Christian Grütter, Heidi Roschitzki-Voser, Peer R.E. Mittl, Markus G. Grütter

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 841 KB

english, 2009

76

Structural Determinants for Improved Stability of Designed Ankyrin Repeat Proteins with a Redesigned C-Capping Module

Michaela A. Kramer, Svava K. Wetzel, Andreas Plückthun, Peer R.E. Mittl, Markus G. Grütter

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.43 MB

english, 2010

77

Projection Structure of the Secondary Citrate/Sodium Symporter CitS at 6 Å Resolution by Electron Crystallography

Fabian Kebbel, Mareike Kurz, Markus G. Grütter, Henning Stahlberg

Journal:

Journal of Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1.36 MB

english, 2012

78

Designed ankyrin repeat protein binders for the crystallization of AcrB: Plasticity of the dominant interface

Nicole Monroe, Gaby Sennhauser, Markus A. Seeger, Christophe Briand, Markus G. Grütter

Journal:

Journal of Structural Biology

Year:

2011

Language:

english

File:

PDF, 3.06 MB

english, 2011

79

Human caspases in vitro: Expression, purification and kinetic characterization

Heidi Roschitzki-Voser, Thilo Schroeder, Esther D. Lenherr, Franziska Frölich, Andreas Schweizer, Mrudula Donepudi, Rajkumar Ganesan, Peer R.E. Mittl, Antonio Baici, Markus G. Grütter

Journal:

Protein Expression and Purification

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

80

Structure-based design of aliskiren, a novel orally effective renin inhibitor

Jeanette M Wood, Jürgen Maibaum, Joseph Rahuel, Markus G Grütter, Nissim-Claude Cohen, Vittorio Rasetti, Heinrich Rüger, Richard Göschke, Stefan Stutz, Walter Fuhrer, Walter Schilling, Pascal Rigollie

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 267 KB

english, 2003

81

Crystal structure of neuroserpin: a neuronal serpin involved in a conformational disease

Christophe Briand, Serguei V. Kozlov, Peter Sonderegger, Markus G. Grütter

Journal:

Year:

2001

Language:

english

File:

PDF, 356 KB

english, 2001

82

Identification of a basic surface area of the FADD death effector domain critical for apoptotic signaling

Markus Kaufmann, Damir Bozic, Christophe Briand, Jean-Luc Bodmer, Oliver Zerbe, Andreas Kohl, Jürg Tschopp, Markus G. Grütter

Journal:

Year:

2002

Language:

english

File:

PDF, 685 KB

english, 2002

83

Structural analysis of mycobacterial and murine hsp60 epitopes in complex with the class I MHC molecule H-2Db

Carlo Ciatto, Guido Capitani, Alain C. Tissot, Frédéric Pecorari, Andreas Plückthun, Markus G. Grütter

Journal:

Year:

2003

Language:

english

File:

PDF, 309 KB

english, 2003

84

The critical structural role of a highly conserved histidine residue in group II amino acid decarboxylases

Guido Capitani, Angela Tramonti, Francesco Bossa, Markus G. Grütter, Daniela De Biase

Journal:

Year:

2003

Language:

english

File:

PDF, 142 KB

english, 2003

85

Insights into the Regulatory Mechanism for Caspase-8 Activation

Mrudula Donepudi, Aengus Mac Sweeney, Christophe Briand, Markus G Grütter

Journal:

Year:

2003

Language:

english

File:

PDF, 236 KB

english, 2003

86

Structure of ACC synthase inactivated by the mechanism-based inhibitor l-vinylglycine

Guido Capitani, Markus Tschopp, Andrew C. Eliot, Jack F. Kirsch, Markus G. Grütter

Journal:

Year:

2005

Language:

english

File:

PDF, 298 KB

english, 2005

87

Caspases: key players in programmed cell death

Markus G Grütter

Journal:

Current Opinion in Structural Biology

Year:

2000

Language:

english

File:

PDF, 476 KB

english, 2000

88

Thermodynamic stability and point mutations of bacteriophage T4 lysozyme

Richard Hawkes, Markus G. Grutter, John Schellman

Journal:

Journal of Molecular Biology

Year:

1984

Language:

english

File:

PDF, 1.20 MB

english, 1984

89

The structure of the adenovirus capsid: I. An envelope model of hexon at 6 Å resolution

Roger M. Burnett, Markus G. Grütter, Janice L. White

Journal:

Journal of Molecular Biology

Year:

1985

Language:

english

File:

PDF, 8.29 MB

english, 1985

90

Crystallization of human leukocyte elastase with its inhibitor Pro44-eglin c

Dirk W. Heinz, Manfred Liersch, Markus G. Grütter

Journal:

Journal of Molecular Biology

Year:

1989

Language:

english

File:

PDF, 206 KB

english, 1989

91

Refolding, isolation and characterization of crystallizable human interferon-α8 expressed in Saccharomyces cerevisiae

Stefania Di Marco, Gabriele Fendrich, Bernd Meyhack, Markus G. Grütter

Journal:

Journal of Biotechnology

Year:

1996

Language:

english

File:

PDF, 1022 KB

english, 1996

92

The crystal structures of recombinant glycosylated human renin alone and in complex with a transition state analog inhibitor

Joseph Rahuel, John P. Priestle, Markus G. Grütter

Journal:

Journal of Structural Biology

Year:

1991

Language:

english

File:

PDF, 13.76 MB

english, 1991

93

The structure of murine interleukin-1 β at 2.8 Å resolution

Jan Van Oostrum, John P. Priestle, Markus G. Grutter, Albert Schmitz

Journal:

Journal of Structural Biology

Year:

1991

Language:

english

File:

PDF, 785 KB

english, 1991

94

Autoproteolytic and Catalytic Mechanisms for the β-Aminopeptidase BapA—A Member of the Ntn Hydrolase Family

Tobias Merz, Tobias Heck, Birgit Geueke, Peer R.E. Mittl, Christophe Briand, Dieter Seebach, Hans-Peter E. Kohler, Markus G. Grütter

Journal:

Year:

2012

Language:

english

File:

PDF, 1.63 MB

english, 2012

95

Crystal Structure of the Anti-His Tag Antibody 3D5 Single-chain Fragment Complexed to its Antigen

Markus Kaufmann, Peter Lindner, Annemarie Honegger, Kerstin Blank, Markus Tschopp, Guido Capitani, Andreas Plückthun, Markus G. Grütter

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 1.27 MB

english, 2002

96

Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation

Hohl, Michael, Briand, Christophe, Grütter, Markus G, Seeger, Markus A

Journal:

Nature Structural and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1.64 MB

english, 2012

97

Specific Inhibition of Caspase-3 by a Competitive DARPin: Molecular Mimicry between Native and Designed Inhibitors

Schroeder, Thilo, Barandun, Jonas, Flütsch, Andreas, Briand, Christophe, Mittl, Peer R.E., Grütter, Markus G.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.91 MB

english, 2013

98

Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and -10

Ekici, Özlem Doǧan, Li, Zhao Zhao, Campbell, Amy J., James, Karen Ellis, Asgian, Juliana L., Mikolajczyk, Jowita, Salvesen, Guy S., Ganesan, Rajkumar, Jelakovic, Stjepan, Grütter, Markus G., Powers, J

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 531 KB

english, 2006

99

Precision is essential for efficient catalysis in an evolved Kemp eliminase

Blomberg, Rebecca, Kries, Hajo, Pinkas, Daniel M., Mittl, Peer R. E., Grütter, Markus G., Privett, Heidi K., Mayo, Stephen L., Hilvert, Donald

Journal:

Year:

2013

Language:

english

File:

PDF, 705 KB

english, 2013

100

Dibenzosuberones as p38 Mitogen-Activated Protein Kinase Inhibitors with Low ATP Competitiveness and Outstanding Whole Blood Activity

Fischer, Stefan, Wentsch, Heike K., Mayer-Wrangowski, Svenja C., Zimmermann, Markus, Bauer, Silke M., Storch, Kirsten, Niess, Raimund, Koeberle, Solveigh C., Grütter, Christian, Boeckler, Frank M., Ra

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 2.85 MB

english, 2013

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