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51

10.1038/26277

Roberts, Fiona, Roberts, Craig W., Johnson, Jennifer J., Kyle, Dennis E., Krell, Tino, Coggins, John R., Coombs, Graham H., Milhous, Wilbur K., Tzipori, Saul, Ferguson, David J. P., Chakrabarti, Debop

Journal:

Year:

1998

Language:

english

File:

PDF, 131 KB

english, 1998

52

10.1038/31723

McLeod, Rima, Roberts, Fiona, Roberts, Craig W., Johnson, Jennifer J., Kyle, Dennis E., Krell, Tino, Coggins, John R., Coombs, Graham H., Milhous, Wilbur K., Tzipori, Saul, Ferguson, David J. P., Chak

Journal:

Year:

1998

Language:

english

File:

PDF, 337 KB

english, 1998

53

Cysteine or serine proteinase?

MOTTRAM, JEREMY C., COOMBS, GRAHAM H., NORTH, MICHAEL J.

Journal:

Year:

1989

File:

PDF, 151 KB

1989

54

Isolation of a lactoferrin cDNA clone and its expression in human breast cancer

Campbell, T, Skilton, RA, Coombes, RC, Shousha, S, Graham, MD, Luqmani, YA

Journal:

British Journal of Cancer

Year:

1992

Language:

english

File:

PDF, 3.72 MB

english, 1992

55

Proteome Analysis of Highly Immunoreactive Proteins of Helicobacter pylori

Robert A. Lock, Geoffrey W. Coombs, Tracy M. McWilliams, John W. Pearman, Warren B. Grubb, Graham J. H. Melrose, Geoffrey M. Forbes

Journal:

Year:

2002

Language:

english

File:

PDF, 259 KB

english, 2002

56

Electrochemical one-electron oxidation of [Ru(NO)Cl5]2?: spectroscopic and magnetic evidence for the (t2g 5) ruthenium (III) pentachloronitrosyl complex monoanion [Ru(NO)Cl5]?

Coombe, Vyvyan T., Heath, Graham A., Stephenson, T. Anthony, Tocher, Derek A.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1983

Language:

english

File:

PDF, 196 KB

english, 1983

57

Proteinases of Leishmania mexicana amastigotes and promastigotes: Analysis by gel electrophoresis

Michael J. North, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

1981

Language:

english

File:

PDF, 444 KB

english, 1981

58

Respiration of Leishmania mexicana amastigotes and promastigotes

David T. Hart, Keith Vickerman, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

1981

Language:

english

File:

PDF, 637 KB

english, 1981

59

The effects of carbon dioxide and oxygen upon the growth and in vitro transformation of Leishmania mexicana mexicana

David T. Hart, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

1981

Language:

english

File:

PDF, 500 KB

english, 1981

60

A comparative study of Leishmania mexicana amastigotes and promastigotes, enzyme activities and subcellular locations

Graham H. Coombs, John A. Craft, David T. Hart

Journal:

Molecular and Biochemical Parasitology

Year:

1982

Language:

english

File:

PDF, 967 KB

english, 1982

61

A comparative study of the proteolytic enzymes of Trypanosoma brucei, T. equiperdum, T. evansi, T. vivax, Leishmania tarentolae and Crithidia fasciculata

Michael J. North, Graham H. Coombs, J.David Barry

Journal:

Molecular and Biochemical Parasitology

Year:

1983

Language:

english

File:

PDF, 825 KB

english, 1983

62

Purine-metabolising enzymes in Entamoeba histolytica

Husain F. Hassan, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

1986

Language:

english

File:

PDF, 585 KB

english, 1986

63

S-adenosylhomocysteine hydrolase activity in Trichomonas vaginalis and other trichomonads

Kam-Wah Thong, Graham H. Coombs, Barbara E. Sanderson

Journal:

Molecular and Biochemical Parasitology

Year:

1985

Language:

english

File:

PDF, 480 KB

english, 1985

64

Polyamine biosynthesis in trichomonads

Michael J. North, Barbara C. Lockwood, Alison F. Bremner, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

1986

Language:

english

File:

PDF, 663 KB

english, 1986

65

Phosphomonoesterases of Leishmania mexicana mexicana and other flagellates

Husain F. Hassan, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

1987

Language:

english

File:

PDF, 915 KB

english, 1987

66

l-Methionine catabolism in trichomonads

Kam-Wah Thong, Graham H. Coombs, Barbara E. Sanderson

Journal:

Molecular and Biochemical Parasitology

Year:

1987

Language:

english

File:

PDF, 626 KB

english, 1987

67

The use of a highly sensitive electrophoretic method to compare the proteinases of trichomonads

Barbara C. Lockwood, Michael J. North, Karen I. Scott, Alison F. Bremner, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

1987

Language:

english

File:

PDF, 683 KB

english, 1987

68

Folate utilisation by Leishmania species and the identification of intracellular derivatives and folate-metabolising enzymes

David A. Scott, Graham H. Coombs, Barbara E. Sanderson

Journal:

Molecular and Biochemical Parasitology

Year:

1987

Language:

english

File:

PDF, 862 KB

english, 1987

69

The release of hydrolases from Trichomonas vaginalis and Tritrichomonas foetus

Barbara C. Lockwood, Michael J. North, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

1988

Language:

english

File:

PDF, 656 KB

english, 1988

70

The specificity of trichomonad cysteine proteinases analysed using fluorogenic substrates and specific inhibitors

Michael J. North, Colin D. Robertson, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

1990

Language:

english

File:

PDF, 989 KB

english, 1990

71

Changes in hepatic xenobiotic-metabolising enzymes in mouse liver following infection with Leishmania donovani

Graham H. Coombs, C. Roland Wolf, Valerie M. Morrison, John A. Craft

Journal:

Molecular and Biochemical Parasitology

Year:

1990

Language:

english

File:

PDF, 859 KB

english, 1990

72

Characterisation of three groups of cysteine proteinases in the amastigotes of Leishmania mexicana mexicana

Colin D. Robertson, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

1990

Language:

english

File:

PDF, 1.03 MB

english, 1990

73

Conservation of cation-transporting ATPase genes in Leishmania

John C. Meade, Graham H. Coombs, Jeremy C. Mottram, Paul E. Steele, James R. Stringer

Journal:

Molecular and Biochemical Parasitology

Year:

1991

Language:

english

File:

PDF, 741 KB

english, 1991

74

Cathepsin B-like cysteine proteases of Leishmania mexicana

Colin D. Robertson, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

1993

Language:

english

File:

PDF, 765 KB

english, 1993

75

Null mutants for the lmcpa cysteine proteinase gene in Leishmania mexicana

Augustine E. Souza, Paul A. Bates, Graham H. Coombs, Jeremy C. Mottram

Journal:

Molecular and Biochemical Parasitology

Year:

1994

Language:

english

File:

PDF, 762 KB

english, 1994

76

Isolation of lmcpc, a gene encoding a Leishmania mexicana cathepsin-B-like cysteine proteinase

Genevieve Bart, Graham H. Coombs, Jeremy C. Mottram

Journal:

Molecular and Biochemical Parasitology

Year:

1995

Language:

english

File:

PDF, 429 KB

english, 1995

77

Comparison of the phosphofructokinase and pyruvate kinase activities of Cryptosporidium parvum, Eimeria tenella and Toxoplasma gondii

Helen Denton, Samantha M.A. Brown, Craig W. Roberts, James Alexander, Vincent McDonald, Kam-Wah Thong, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

1996

Language:

english

File:

PDF, 674 KB

english, 1996

78

Purification of particulate malate dehydrogenase and phosphoenolpyruvate carboxykinase from Leishmania mexicana mexicana

Jeremy C. Mottram, Graham H. Coombs

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1985

Language:

english

File:

PDF, 821 KB

english, 1985

79

Leishmania donovani: Differential activities of classical topoisomerase inhibitors and antileishmanials against parasite and host cells at the level of DNA topoisomerase I and in cytotoxicity assays

Valerie Jean-Moreno, Ricardo Rojas, Diego Goyeneche, Graham H. Coombs, John Walker

Journal:

Experimental Parasitology

Year:

2006

Language:

english

File:

PDF, 286 KB

english, 2006

80

Leishmania panamensis: Comparative inhibition of nuclear DNA topoisomerase II enzymes from promastigotes and human macrophages reveals anti-parasite selectivity of fluoroquinolones, flavonoids and pentamidine

Tania M. Cortázar, Graham H. Coombs, John Walker

Journal:

Experimental Parasitology

Year:

2007

Language:

english

File:

PDF, 254 KB

english, 2007

81

The role of conserved residues of chagasin in the inhibition of cysteine peptidases

Flavia C.G. dos Reis, Brian O. Smith, Camila C. Santos, Tatiana F.R., Costa, Julio Scharfstein, Graham H. Coombs, Jeremy C. Mottram, Ana Paula C.A. Lima

Journal:

Year:

2008

Language:

english

File:

PDF, 420 KB

english, 2008

82

Protein turnover and differentiation in Leishmania

Sébastien Besteiro, Roderick A.M. Williams, Graham H. Coombs, Jeremy C. Mottram

Journal:

International Journal for Parasitology

Year:

2007

Language:

english

File:

PDF, 1.33 MB

english, 2007

83

Specific negative charges in cysteine protease isoforms of Leishmania mexicana are highly influential on the substrate binding and hydrolysis

Wagner A.S. Judice, Jeremy C. Mottram, Graham H. Coombs, Maria A. Juliano, Luiz Juliano

Journal:

Molecular and Biochemical Parasitology

Year:

2005

Language:

english

File:

PDF, 487 KB

english, 2005

84

Differentiation of Leishmania major is impaired by over-expression of pyroglutamyl peptidase I

Marie Schaeffer, Antonio de Miranda, Jeremy C. Mottram, Graham H. Coombs

Journal:

Molecular and Biochemical Parasitology

Year:

2006

Language:

english

File:

PDF, 691 KB

english, 2006

85

Expression and substrate specificity of a recombinant cysteine proteinase B of Leishmania braziliensis

Maria F. Lanfranco, Raúl Loayza-Muro, Daniel Clark, Regina Núñez, Amparo I. Zavaleta, Maribel Jimenez, Morten Meldal, Graham H. Coombs, Jeremy C. Mottram, Mario Izidoro, Maria A. Juliano, Luiz Juliano

Journal:

Molecular and Biochemical Parasitology

Year:

2008

Language:

english

File:

PDF, 1.10 MB

english, 2008

86

Oligopeptidase B deficient mutants of Leishmania major

Jane C. Munday, Karen McLuskey, Elaine Brown, Graham H. Coombs, Jeremy C. Mottram

Journal:

Molecular and Biochemical Parasitology

Year:

2011

Language:

english

File:

PDF, 863 KB

english, 2011

87

Leishmaniasis– current chemotherapy and recent advances in the search for novel drugs

Simon L. Croft, Graham H. Coombs

Journal:

Trends in Parasitology

Year:

2003

Language:

english

File:

PDF, 307 KB

english, 2003

88

Putrescine and spermidine transport in Leishmania

Mireille Basselin, Graham H Coombs, Michael P Barrett

Journal:

Molecular and Biochemical Parasitology

Year:

2000

Language:

english

File:

PDF, 147 KB

english, 2000

89

Identification of peptides inhibitory to recombinant cysteine proteinase, CPB, of Leishmania mexicana

Lira C Alves, Phaedria M St. Hilaire, Morten Meldal, Sanya J Sanderson, Jeremy C Mottram, Graham H Coombs, Luiz Juliano, Maria A Juliano

Journal:

Molecular and Biochemical Parasitology

Year:

2001

Language:

english

File:

PDF, 121 KB

english, 2001

90

Substrate specificity of recombinant cysteine proteinase, CPB, of Leishmania mexicana

Lira C Alves, Wagner A.S Judice, Phaedria M.St Hilaire, Morten Meldal, Sanya J Sanderson, Jeremy C Mottram, Graham H Coombs, Luiz Juliano, Maria A Juliano

Journal:

Molecular and Biochemical Parasitology

Year:

2001

Language:

english

File:

PDF, 123 KB

english, 2001

91

Analysis of the S2 subsite specificities of the recombinant cysteine proteinases CPB of Leishmania mexicana, and cruzain of Trypanosoma cruzi, using fluorescent substrates containing non-natural basic amino acids

Lira C Alves, Robson L Melo, Maria Helena S Cezari, Sanya J Sanderson, Jeremy C Mottram, Graham H Coombs, Luiz Juliano, Maria A Juliano

Journal:

Molecular and Biochemical Parasitology

Year:

2001

Language:

english

File:

PDF, 119 KB

english, 2001

92

Cathepsin B-like cysteine proteinase-deficient mutants of Leishmania mexicana

Genevieve Bart, Mhairi J Frame, Roderick Carter, Graham H Coombs, Jeremy C Mottram

Journal:

Molecular and Biochemical Parasitology

Year:

1997

Language:

english

File:

PDF, 193 KB

english, 1997

93

Leishmania Cysteine Proteinases: Virulence Factors in Quest of a Function—Reply

Jeremy C Mottram, Graham H Coombs

Journal:

Parasitology Today

Year:

1998

Language:

english

File:

PDF, 46 KB

english, 1998

94

Targeting polyamines of parasitic protozoa in chemotherapy

Sylke Müller, Graham H. Coombs, Rolf D. Walter

Journal:

Trends in Parasitology

Year:

2001

Language:

english

File:

PDF, 412 KB

english, 2001

95

Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets

Graham H. Coombs, Daniel E. Goldberg, Michael Klemba, Colin Berry, John Kay, Jeremy C. Mottram

Journal:

Trends in Parasitology

Year:

2001

Language:

english

File:

PDF, 87 KB

english, 2001

96

The diversity and evolution of thioredoxin reductase: new perspectives

Robert P. Hirt, Sylke Müller, T. Martin Embley, Graham H. Coombs

Journal:

Trends in Parasitology

Year:

2002

Language:

english

File:

PDF, 69 KB

english, 2002

97

Clan CD cysteine peptidases of parasitic protozoa

Jeremy C. Mottram, Matthew J. Helms, Graham H. Coombs, Mohammed Sajid

Journal:

Trends in Parasitology

Year:

2003

Language:

english

File:

PDF, 193 KB

english, 2003

98

The SNARE protein family ofLeishmania major

Sébastien Besteiro, Graham H Coombs, Jeremy C Mottram

Journal:

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

99

Ecotin-like serine peptidase inhibitor ISP1 of Leishmania major plays a role in flagellar pocket dynamics and promastigote differentiation

Lesley S. Morrison, Amy Goundry, Marilia S. Faria, Laurence Tetley, Sylvain C. Eschenlauer, Gareth D. Westrop, Anna Dostalova, Petr Volf, Graham H. Coombs, Ana Paula C. A. Lima, Jeremy C. Mottram

Journal:

Cellular Microbiology

Year:

2012

Language:

english

File:

PDF, 4.34 MB

english, 2012

100

Preliminary Investigations into Macroscopic Attenuated Total Reflection–Fourier Transform Infrared Imaging of Intact Spherical Domains: Spatial Resolution and Image Distortion

Everall, Neil J., Priestnall, Ian M., Clarke, Fiona, Jayes, Linda, Poulter, Graham, Coombs, David, George, Michael W.

Journal:

Applied Spectroscopy

Year:

2009

Language:

english

File:

PDF, 872 KB

english, 2009

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