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1

Stimulation by adriamycin of rat heart and liver microsomal NADPH-dependent lipid peroxidation

Edward G. Mimnaugh, Michael A. Trush, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1981

Language:

english

File:

PDF, 1012 KB

english, 1981

2

Distribution of 14c-lomustine (14c-ccnu)-derived radioactivity following intravenous administration of three potential clinical formulations to rabbits

Charles L. Litterst, Edward G. Mimnaugh, Theodore E. Gram, Anthony M. Guarino, Alan C. Cowles

Journal:

Journal of Pharmaceutical Sciences

Year:

1974

Language:

english

File:

PDF, 437 KB

english, 1974

3

Moclobemide, a substrate of CYP2C19 and an inhibitor of CYP2C19, CYP2D6, and CYP1A2: A panel study*

Gram, Lars F., Guentert, Theodor W., Grange, Susan, Vistisen, Kirsten, Brøsen, Kim

Journal:

Clinical Pharmacology & Therapeutics

Year:

1995

Language:

english

File:

PDF, 817 KB

english, 1995

4

A comparison of the pulmonary toxicity and chemotherapeutic activity of bleomycin-BAPP to bleomycin and pepleomycin

Erika Ginsburg, Theodore E. Gram, Michael A. Trush

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1984

Language:

english

File:

PDF, 438 KB

english, 1984

5

Pulmonary accumulation of drugs in vitamin a deficiency

Zahid H. Siddik, Michael A. Trush, Theodore E. Gram

Journal:

Year:

1979-1980

Language:

english

File:

PDF, 473 KB

english, 1979-1980

6

Interaction of the oncolytic drug, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea with the mixed-function oxidase system in rats

Samuel Tong, Yoichiro Hirokata, Charles L. Litterst, Theodore E. Gram

Journal:

Chemico-Biological Interactions

Year:

1984

Language:

english

File:

PDF, 773 KB

english, 1984

7

The metabolism of drugs by hepatic microsomal enzymes. Studies on intramicrosomal distribution of enzymes and relationships between enzyme activity and structure of the hepatic endoplasmic reticulum

James R. Fouts, Larry A. Rogers, Theodore E. Gram

Journal:

Experimental and Molecular Pathology

Year:

1966

Language:

english

File:

PDF, 3.17 MB

english, 1966

8

Bronchiolar epithelial damage and impairment of pulmonary microsomal monooxygenase activity in mice by naphthalene

Samuel S Tong, Michael C Lowe, Michael A Trush, Edward G Mimnaugh, Erika Ginsburg, Yoichiro Hirokata, Theodore E Gram

Journal:

Experimental and Molecular Pathology

Year:

1982

Language:

english

File:

PDF, 3.86 MB

english, 1982

9

The effects of adriamycin in vitro and in vivo on hepatic microsomal drug-metabolizing enzymes: Role of microsomal lipid peroxidation

Edward G. Mimnaugh, Michael A. Trush, Erika Ginsburg, Yoichiro Hirokata, Theodore E. Gram

Journal:

Toxicology and Applied Pharmacology

Year:

1981

Language:

english

File:

PDF, 1.01 MB

english, 1981

10

Selective damage to nonciliated bronchiolar epithelial cells in relation to impairment of pulmonary monooxygenase activities by 1,1-dichloroethylene in mice

Klaas R. Krijgsheld, Michael C. Lowe, Edward G. Mimnaugh, Michael A. Trush, Erika Ginsburg, Theodore E. Gram

Journal:

Toxicology and Applied Pharmacology

Year:

1984

Language:

english

File:

PDF, 7.98 MB

english, 1984

11

In vitro stimulation by paraquat of reactive oxygen-mediated lipid peroxidation in rat lung microsomes

Michael A. Trush, Edward G. Mimnaugh, Erika Ginsburg, Theodore E. Gram

Journal:

Toxicology and Applied Pharmacology

Year:

1981

Language:

english

File:

PDF, 705 KB

english, 1981

12

The kinetics of 32P incorporation into the phospholipids of hepatic rough and smooth microsomal membranes of male and female rats

Jordan L. Holtzman, Theodore E. Gram, James R. Gillette

Journal:

Archives of Biochemistry and Biophysics

Year:

1970

Language:

english

File:

PDF, 781 KB

english, 1970

13

The effects of ascorbic acid deficiency and repletion on pulmonary, renal, and hepatic drug metabolism in the guinea pig

Branimir Ivan Sikic, Edward G. Mimnaugh, Charles L. Litterst, Theodore E. Gram

Journal:

Archives of Biochemistry and Biophysics

Year:

1977

Language:

english

File:

PDF, 752 KB

english, 1977

14

Lung-selective impairment of cytochrome P-450-dependent monooxygenases and cellular injury by 1,1-dichloroethylene in mice

Klaas R. Krijgsheld, Michael C. Lowe, Edward G. Mimnaugh, Michael A. Trush, Erika Ginsburg, Theodore E. Gram

Journal:

Biochemical and Biophysical Research Communications

Year:

1983

Language:

english

File:

PDF, 1.74 MB

english, 1983

15

Lack of metaraminol biotransformation by rabbit tissues in vitro

Theodore E. Gram, Harold N. Wright

Journal:

Biochemical Pharmacology

Year:

1965

Language:

english

File:

PDF, 351 KB

english, 1965

16

Effect of partial hepatectomy on the responsiveness of microsomal enzymes and cytochrome P-450 to phenobarbital or 3-methylcholanthrene

Theodore E. Gram, Anthony M. Guarino, Frank E. Greene, Philippe L. Gigon, James R. Gillette

Journal:

Biochemical Pharmacology

Year:

1968

Language:

english

File:

PDF, 767 KB

english, 1968

17

The influence of age, sex and drug treatment on microsomal drug metabolism in four rat strains

Raymond L. Furner, Theodore E. Gram, Robert E. Stitzel

Journal:

Biochemical Pharmacology

Year:

1969

Language:

english

File:

PDF, 581 KB

english, 1969

18

Further studies on the submicrosomal distribution of drug-metabolizing components in liver: Localization in fractions of smooth microsomes

Theodore E. Gram, David H. Schroeder, Donald C. Davis, R.L. Reagan, Anthony M. Guarino

Journal:

Biochemical Pharmacology

Year:

1971

Language:

english

File:

PDF, 1.50 MB

english, 1971

19

Enzymic and biochemical composition of smooth and rough microsomal membranes from monkey, guinea pig and mouse liver

Theodore E. Gram, David H. Schroeder, Donald C. Davis, Reginald L. Reagan, Anthony M. Guarino

Journal:

Biochemical Pharmacology

Year:

1971

Language:

english

File:

PDF, 1.25 MB

english, 1971

20

Effect of storage on microsomal mixed function oxidase activity in mouse liver

Charles L. Litterst, Edward G. Mimnaugh, Reginald L. Reagan, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1974

Language:

english

File:

PDF, 967 KB

english, 1974

21

Effects of activators in vitro on rabbit lung and liver microsomal UDP-glucuronyl-transferase activity

Edward G. Mimnaugh, Charles L. Litterst, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1975

Language:

english

File:

PDF, 428 KB

english, 1975

22

Effects of dietary ascorbic acid supplementation on hepatic drug-metabolizing enzymes in the guinea pig

Branimir Ivan Sikic, Edward G. Mimnaugh, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1977

Language:

english

File:

PDF, 609 KB

english, 1977

23

Lack of correlation between cortisol-induced precocious maturation of the fetal rabbit lung and drug metabolism

Zahid H. Siddik, Branimir I. Sikic, Roger Drew, Edward G. Mimnaugh, Charles L. Litterst, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1979

Language:

english

File:

PDF, 315 KB

english, 1979

24

Metabolism and biliary excretion of sulfobromophthalein in vitamin a deficiency

Zahid H. Siddik, Roger Drew, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1980

Language:

english

File:

PDF, 631 KB

english, 1980

25

Sex-dependent differences in the effects of portacaval anastomosis on hepatic monooxygenases in rats

Hirokata Yoichiro, Samuel Tong, Zahid H. Siddik, Michael A. Trush, Edward G. Mimnaugh, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1982

Language:

english

File:

PDF, 458 KB

english, 1982

26

Studies on the in vitro interaction of mitomycin C, nitrofurantoin and paraquat with pulmonary microsomes: Stimulation of reactive oxygen-dependent lipid peroxidation

Michael A. Trush, Edward G. Mimnaugh, Erika Ginsburg, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1982

Language:

english

File:

PDF, 999 KB

english, 1982

27

Activation of pharmacologic agents to radical intermediates: Implications for the role of free radicals in drug action and toxicity

Michael A. Trush, Edward G. Mimnaugh, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1982

Language:

english

File:

PDF, 1.08 MB

english, 1982

28

Selective induction of renal microsomal cytochrome P-450-linked monooxygenases by 1,1-dichloroethylene in mice

Klaas R. Krijgsheld, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1984

Language:

english

File:

PDF, 576 KB

english, 1984

29

Studies on the distribution and co valent binding of 1,1-dichloroethylene in the mouse: Effect of various pretreatments on covalent binding in vivo

Laud K. Okine, Janet M. Goochee, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 886 KB

english, 1985

30

Enhancement of reactive oxygen-dependent mitochondrial membrane lipid peroxidation by the anticancer drug adriamycin

Edward G. Mimnaugh, Michael A. Trush, Mohit Bhatnagar, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 918 KB

english, 1985

31

In vitro studies on the metabolism and co valent binding of [14C]1,1-dichloroethylene by mouse liver, kidney and lung

Laud K. Okine, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1986

Language:

english

File:

PDF, 849 KB

english, 1986

32

A possible role for membrane lipid peroxidation in anthracycline nephrotoxicity

Edward G. Mimnaugh, Michael A. Trush, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1986

Language:

english

File:

PDF, 857 KB

english, 1986

33

Metabolic activation and toxicity of some chemical agents to lung tissue and cells

Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 834 KB

english, 1995

34

The effects of α-tocopherol on the toxicity, disposition, and metabolism of adriamycin in mice

Edward G. Mimnaugh, Zahid H. Siddik, Roger Drew, Branimir I. Sikic, Theodore E. Gram

Journal:

Toxicology and Applied Pharmacology

Year:

1979

Language:

english

File:

PDF, 633 KB

english, 1979

35

Vehicle alteration of paraquat lethality in mice

Roger Drew, Theodore E. Gram

Journal:

Toxicology and Applied Pharmacology

Year:

1979

Language:

english

File:

PDF, 662 KB

english, 1979

36

The effect of chlorpromazine on the uptake and efflux of paraquat in rat lung slices

Zahid H. Siddik, Roger Drew, Theodore E. Gram

Journal:

Toxicology and Applied Pharmacology

Year:

1979

Language:

english

File:

PDF, 679 KB

english, 1979

37

Uptake and efflux of 14C-paraquat by rat lung slices: The effect of imipramine and other drugs

Roger Drew, Zahid H. Siddik, Theodore E. Gram

Journal:

Toxicology and Applied Pharmacology

Year:

1979

Language:

english

File:

PDF, 467 KB

english, 1979

38

Clara cell damage and inhibition of pulmonary mixed-function oxidase activity by naphthalene

Samuel S. Tong, Yoichiro Hirokata, Michael A. Trush, Edward G. Mimnaugh, Erika Ginsburg, Michael C. Lowe, Theodore E. Gram

Journal:

Biochemical and Biophysical Research Communications

Year:

1981

Language:

english

File:

PDF, 370 KB

english, 1981

39

Comparative alterations in extrahepatic drug metabolism by factors known to affect hepatic activity

Charles L. Litterst, Edward G. Mimnaugh, Theodore E. Gram

Journal:

Biochemical Pharmacology

Year:

1977

Language:

english

File:

PDF, 775 KB

english, 1977

40

Pulmonary toxicity of 4-ipomeanol

Theodore E. Gram

Journal:

Pharmacology & Therapeutics

Year:

1989

Language:

english

File:

PDF, 885 KB

english, 1989

41

Effect of α-tocopherol upon lipid peroxidation and drug metabolism in hepatic microsomes

Theodore E. Gram, James R. Fouts

Journal:

Archives of Biochemistry and Biophysics

Year:

1966

Language:

english

File:

PDF, 482 KB

english, 1966

42

Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH

Philippe L. Gigon, Theodore E. Gram, James R. Gillette

Journal:

Biochemical and Biophysical Research Communications

Year:

1968

Language:

english

File:

PDF, 244 KB

english, 1968

43

Drug metabolism by microsomes from extrahepatic organs of rat and rabbit prepared by calcium aggregation

Charles L. Litterst, Edward G. Mimnaugh, Reginald L. Reagan, Theodore E. Gram

Journal:

Year:

1975

Language:

english

File:

PDF, 274 KB

english, 1975

44

In vitro drug metabolism in male and female athymic, nude mice

Charles L. Litterst, Branimir I. Sikic, Edward G. Mimnaugh, Anthony M. Guarino, Theodore E. Gram

Journal:

Year:

1978

Language:

english

File:

PDF, 380 KB

english, 1978

45

The distribution of 14C-imipramine in mice bearing lewis lung carcinoma

Roger Drew, Branimir I. Sikic, Edward G. Mimnaugh, Charles L. Litterst, Theodore E. Gram

Journal:

Year:

1979

Language:

english

File:

PDF, 360 KB

english, 1979

46

Sex differences in the uptake and retention of imipramine and desmethylimipramine in the rat lung

Erika Ginsburg, Yoichiro Hirokata, Theodore E. Gram

Journal:

Year:

1982

Language:

english

File:

PDF, 212 KB

english, 1982

47

Sam II aerosol profile measurements, Poker Flat, Alaska; July 16-19, 1979

McCormick, M. Patrick, Chu, William P., McMaster, Leonard R., Grams, Gerald W., Herman, Benjamin M., Pepin, Theodore J., Russell, Philip B., Swissler, Thomas J.

Journal:

Geophysical Research Letters

Year:

1981

Language:

english

File:

PDF, 162 KB

english, 1981

48

The relation between invertebrate drift and two primary controls, discharge and benthic densities, in a large regulated river

Kennedy, Theodore A., Yackulic, Charles B., Cross, Wyatt F., Grams, Paul E., Yard, Michael D., Copp, Adam J.

Journal:

Freshwater Biology

Year:

2014

Language:

english

File:

PDF, 609 KB

english, 2014

49

Protection by Methylprednisolone against Butylated Hydroxytoluene-Induced Pulmonary Damage and Impairment of Microsomal Monooxygenase Activities in the Mouse: Lack of Effect on Fibrosis

Okine, Laud K., Lowe, Michael C., Mimnaugh, Edward G., Goochee, Janet M., Gram, Theodore E.

Journal:

Experimental Lung Research

Year:

1986

Language:

english

File:

PDF, 2.70 MB

english, 1986

50

Predicting New Urban Social Organization: Councils of Governments

Aldrich, Brian C., Anderson, Theodore R., Grams, Robert W.

Journal:

Sociological Focus

Year:

1976

Language:

english

File:

PDF, 1005 KB

english, 1976

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