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51

High-performance liquid chromatographic analysis of melphalan in plasma, brain and peripheral tissue by o-phthalaldehyde derivatization and fluorescence detection

Daniel J. Sweeney, Nigel H. Greig, Stanley I. Rapoport

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1985

Language:

english

File:

PDF, 416 KB

english, 1985

52

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β-peptide

Carsten Culmsee, Xiaoxiang Zhu, Qian-Sheng Yu, Sic L. Chan, Simonetta Camandola, Zhihong Guo, Nigel H. Greig, Mark P. Mattson

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 736 KB

english, 2001

53

Development of lipophilic anticancer agents for the treatment of brain tumors by the esterification of water-soluble chlorambucil

Shigeru Genka, Joseph Deutsch, Umesha H. Shetty, Paul L. Stahle, Varghese John, Ivan M. Lieberburg, Francis Ali-Osmant, Stanley I. Rapoport, Nigel H. Greig

Journal:

Clinical and Experimental Metastasis

Year:

1993

Language:

english

File:

PDF, 933 KB

english, 1993

54

Intravenously injected radiolabelled fatty acids image brain tumour phospholipidsin vivo: differential uptakes of palmitate, arachidonate and docosahexaenoate

Tadashi Nariai, Nigel H. Greig, Joseph J. DeGeorge, Shigeru Genka, Stanley I. Rapoport

Journal:

Clinical and Experimental Metastasis

Year:

1993

Language:

english

File:

PDF, 835 KB

english, 1993

55

Enhanced cerebrovascular permeability by Metrazol: significance for brain metastases

Nigel Greig, Kurt Hellmann

Journal:

Clinical and Experimental Metastasis

Year:

1983

Language:

english

File:

PDF, 650 KB

english, 1983

56

Short communication: Metrazol enhances brain penetration and therapeutic efficacy of some anticancer agents: implications for brain metastases

Nigel Greig, David Newell, Kurt Hellmann

Journal:

Clinical and Experimental Metastasis

Year:

1984

Language:

english

File:

PDF, 261 KB

english, 1984

57

Razoxane penetration into the cerebrospinal fluid of rats

Nigel Greig, Fu Xiao-Chang, Kurt Hellmann

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1982

Language:

english

File:

PDF, 189 KB

english, 1982

58

Comparative brain and plasma pharmacokinetics and anticancer activities of chlorambucil and melphalan in the rat

Nigel H. Greig, Daniel J. Sweeney, Stanley I. Rapoport

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1988

Language:

english

File:

PDF, 859 KB

english, 1988

59

Pharmacokinetics of chlorambucil-tertiary butyl ester, a lipophilic chlorambucil derivative that achieves and maintains high concentrations in brain

Nigel H. Greig, Eileen M. Daly, Daniel J. Sweeney, Stanley I. Rapoport

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 707 KB

english, 1990

60

Physicochemical and pharmacokinetic parameters of seven lipophilic chlorambucil esters designed for brain penetration

Nigel H. Greig, Shigeru Genka, Eileen M. Daly, Daniel J. Sweeney, Stanley I. Rapoport

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 1.03 MB

english, 1990

61

Affinity of antineoplastic amino acid drugs for the large neutral amino acid transporter of the blood-brain barrier

Yoshiaki Takada, Nigel H. Greig, David T. Vistica, Stanley I. Rapoport, Quentin R. Smith

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1992

File:

PDF, 27 KB

1992

62

Affinity of antineoplastic amino acid drugs for the large neutral amino acid transporter of the blood-brain barrier

Yoshiaki Takada, Nigel H. Greig, David T. Vistica, Stanley I. Rapoport, Quentin R. Smith

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1991

Language:

english

File:

PDF, 729 KB

english, 1991

63

Brain and plasma pharmacokinetics and anticancer activities of cyclophosphamide and phosphoramide mustard in the rat

Shigeru Genka, Joseph Deutsch, Paul L. Stahle, Umesha H. Shetty, Varghese John, Cynthia Robinson, Stanely I. Rapoport, Nigel H. Greig

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 933 KB

english, 1990

64

Blood-brain barrier integrity and host responses in experimental metastatic brain tumours

Nigel H. Greig, Huw B. Jones, John B. Cavanagh

Journal:

Clinical and Experimental Metastasis

Year:

1983

Language:

english

File:

PDF, 1.18 MB

english, 1983

65

Differences in rates of incorporation of intravenously injected radiolabeled fatty acids into phospholipids of intracerebrally implanted tumor and brain in awake rats

Tadashi Nariai, Joseph J. DeGeorge, Nigel H. Greig, Shigeru Genka, Stanley I. Rapoport, A. David Purdon

Journal:

Clinical and Experimental Metastasis

Year:

1994

Language:

english

File:

PDF, 1.64 MB

english, 1994

66

Phenserine: a physostigmine derivative that is a long-acting inhibitor of cholinesterase and demonstrates a wide dose range for attenuating a scopolamine-induced learning impairment of rats in a 14-unit T-maze

Setsu Iijima, Nigel H. Greig, Paolo Garofalo, Edward L. Spangler, Brett Heller, Arnold Brossi, Donald K. Ingram

Journal:

Psychopharmacology

Year:

1993

Language:

english

File:

PDF, 706 KB

english, 1993

67

Chronic treatment with meta-chlorophenylpiperazine (m-CPP) alters behavioral and cerebral metabolic responses to the serotonin agonists m-CPP and quipazine but not 8-hydroxy-2(di-N-propylamino)tetralin

Ulderico Freo, Harold W. Holloway, Nigel H. Greig, Timothy T. Soncrant

Journal:

Psychopharmacology

Year:

1992

Language:

english

File:

PDF, 904 KB

english, 1992

68

Differential effects of two hexahydropyrroloindole carbamate-based anticholinesterase drugs on the amyloid beta protein pathway involved in alzheimer disease

Debomoy K. Lahiri, George M. Alley, David Tweedie, Demao Chen, Nigel H. Greig

Journal:

NeuroMolecular Medicine

Year:

2007

Language:

english

File:

PDF, 359 KB

english, 2007

69

Brain uptake and anticancer activities of vincristine and vinblastine are restricted by their low cerebrovascular permeability and binding to plasma constituents in rat

Nigel H. Greig, Timothy T. Soncrant, H. Umesha Shetty, Seiji Momma, Quentin R. Smith, Stanley I. Rapoport

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 668 KB

english, 1990

70

Tetrahydrofurobenzofuran cymserine, a potent butyrylcholinesterase inhibitor and experimental Alzheimer drug candidate, enzyme kinetic analysis

Mohammad A. Kamal, Xianqin Qu, Qian-sheng Yu, David Tweedie, Harold W. Holloway, Yazhou Li, Yi Tan, Nigel H. Greig

Journal:

Journal of Neural Transmission

Year:

2008

Language:

english

File:

PDF, 497 KB

english, 2008

71

The alpha-synuclein 5′untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen

Jack T. Rogers, Sohan Mikkilineni, Ippolita Cantuti-Castelvetri, Deborah H. Smith, Xudong Huang, Sanghamitra Bandyopadhyay, Catherine M. Cahill, Maria L. Maccecchini, Debomoy K. Lahiri, Nigel H. Greig

Journal:

Journal of Neural Transmission

Year:

2011

Language:

english

File:

PDF, 788 KB

english, 2011

72

Early-life events may trigger biochemical pathways for Alzheimer’s disease: the “LEARn” model

Debomoy K. Lahiri, Nasser H. Zawia, Nigel H. Greig, Kumar Sambamurti, Bryan Maloney

Journal:

Year:

2008

Language:

english

File:

PDF, 165 KB

english, 2008

73

Kinetics of Human Serum Butyrylcholinesterase Inhibition by a Novel Experimental Alzheimer Therapeutic, Dihydrobenzodioxepine Cymserine

Mohammad A. Kamal, Peter Klein, Weiming Luo, Yazhou Li, Harold W. Holloway, David Tweedie, Nigel H. Greig

Journal:

Neurochemical Research

Year:

2008

Language:

english

File:

PDF, 382 KB

english, 2008

74

Soluble Neuroprotective Antioxidant Uric Acid Analogs Ameliorate Ischemic Brain Injury in Mice

Frank Haberman, Sung-Chun Tang, Thiruma V. Arumugam, Dong-Hoon Hyun, Qian-Sheng Yu, Roy G. Cutler, Zhihong Guo, Harold W. Holloway, Nigel H. Greig, Mark P. Mattson

Journal:

NeuroMolecular Medicine

Year:

2007

Language:

english

File:

PDF, 348 KB

english, 2007

75

A practical conversion of natural physostigmine into the potent butyrylcholinesterase inhibitor N1,N8-bisnorcymserine

Xiaoxiang Zhu, Nigel H Greig, Harold W Holloway, Noel F Whittaker, Arnold Brossi, Qian-sheng Yu

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 111 KB

english, 2000

76

High-performance liquid chromatographic analysis of chlorambucil tert.-butyl ester and its active metabolites chlorambucil and phenylacetic mustard in plasma and tissue

Nigel H. Greig, Paul L. Stahle, H. Umesha Shetty, Shigeru Genka, Varghese John, Timothy T. Soncrant, Stanley I. Rapoport

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1990

Language:

english

File:

PDF, 537 KB

english, 1990

77

High-performance liquid chromatographic assay of bromocriptine in rat plasma and brain

D.Gabrielle Phelan, Nigel H. Greig, Stanley I. Rapoport, Timothy T. Soncrant

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1990

Language:

english

File:

PDF, 463 KB

english, 1990

78

Electron-impact ionization detection of scopolamine by gas chromatography—mass spectrometry in rat plasma and brain

Joseph Deutsch, Timothy T Soncrant, Nigel H Greig, Stanley I Rapoport

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1990

Language:

english

File:

PDF, 407 KB

english, 1990

79

Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity

Joachim Hartmann, Cornelia Kiewert, Ellen G. Duysen, Oksana Lockridge, Nigel H. Greig, Jochen Klein

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 630 KB

english, 2007

80

Enhancing the GLP-1 receptor signaling pathway leads to proliferation and neuroprotection in human neuroblastoma cells

Yazhou Li, David Tweedie, Mark P. Mattson, Harold W. Holloway, Nigel H. Greig

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 557 KB

english, 2010

81

Plumbagin promotes the generation of astrocytes from rat spinal cord neural progenitors via activation of the transcription factor Stat3

Yongquan Luo, Mohamed R. Mughal, Tae-Gen Son Xin Ouyang, Haiyang Jiang, Weiming Luo, Qian-Sheng Yu, Nigel H. Greig, Mark P. Mattson

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 928 KB

english, 2010

82

Targets for AD treatment: conflicting messages from γ-secretase inhibitors

Kumar Sambamurti, Nigel H. Greig, Tadanobu Utsuki, Eliza L. Barnwell, Ekta Sharma, Cheryl Mazell, Narayan R. Bhat, Mark S. Kindy, Debomoy K. Lahiri, Miguel A. Pappolla

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 594 KB

english, 2011

83

Tumor necrosis factor-α synthesis inhibitor, 3,6′-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice

Renana Baratz, David Tweedie, Vardit Rubovitch, Weiming Luo, Jeong Seon Yoon, Barry J. Hoffer, Nigel H. Greig, Chaim G. Pick

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 464 KB

english, 2011

84

Learning from the gut

Mattson, Mark P, Perry, TracyAnn, Greig, Nigel H

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 627 KB

english, 2003

85

The Integrated Role of Desferrioxamine and Phenserine Targeted to an Iron-Responsive Element in the APP-mRNA 5′-Untranslated Region

AMANDA VENTI, TONY GIORDANO, PAUL EDER, ASHLEY I. BUSH, DEBOMOY K. LAHIRI, NIGEL H. GREIG, JACK T. ROGERS

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 2.98 MB

english, 2004

86

New Therapeutic Strategies and Drug Candidates for Neurodegenerative Diseases: p53 and TNF-α Inhibitors, and GLP-1 Receptor Agonists

NIGEL H. GREIG, MARK P. MATTSON, TRACYANN PERRY, SIC L. CHAN, TONY GIORDANO, KUMAR SAMBAMURTI, JACK T. ROGERS, HAIM OVADIA, DEBOMOY K. LAHIRI

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 42.04 MB

english, 2004

87

Melatonin, Metals, and Gene Expression: Implications in Aging and Neurodegenerative Disorders

DEBOMOY K. LAHIRI, DEMAO CHEN, PREETI LAHIRI, JACK T. ROGERS, NIGEL H. GREIG, STEPHEN BONDY

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 1.91 MB

english, 2004

88

Amyloid, Cholinesterase, Melatonin, and Metals and Their Roles in Aging and Neurodegenerative Diseases

DEBOMOY K. LAHIRI, DE-MAO CHEN, PREETI LAHIRI, STEVE BONDY, NIGEL H. GREIG

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 220 KB

english, 2005

89

In vivo biological activity of exendin (1–30)

Máire E. Doyle, Patrick McConville, Michael J. Theodorakis, Margaret M. Goetschkes, Michel Bernier, Richard G. S. Spencer, Harold W. Holloway, Nigel H. Greig, Josephine M. Egan

Journal:

Endocrine (Springer)

Year:

2005

Language:

english

File:

PDF, 496 KB

english, 2005

90

Characterization of the human β-secretase 2 (BACE2) 5′-flanking region

Bryan Maloney, Yuan-Wen Ge, Nigel H. Greig, Debomoy K. Lahiri

Journal:

Journal of Molecular Neuroscience

Year:

2006

Language:

english

File:

PDF, 513 KB

english, 2006

91

Advances in the cellular and molecular biology of the beta-amyloid protein in Alzheimer’s disease

Kumar Sambamurti, Nigel H. Greig, Debomoy K. Lahiri

Journal:

NeuroMolecular Medicine

Year:

2002

Language:

english

File:

PDF, 218 KB

english, 2002

92

p53 is present in synapses where it mediates mitochondrial dysfunction and synaptic degeneration in response to DNA damage, and oxidative and excitotoxic insults

Charles P. Gilman, Sic L. Chan, Zhihong Guo, Xiaoxiang Zhu, Nigel Greig, Mark P. Mattson

Journal:

NeuroMolecular Medicine

Year:

2003

Language:

english

File:

PDF, 1.25 MB

english, 2003

93

GBR12909 antagonizes the ability of cocaine to elevate extracellular levels of dopamine

Richard B. Rothman, Andrea Mele, Audrey A. Reid, Hyacinth C. Akunne, Nigel Greig, Andrew Thurkauf, Brian R. de Costa, Kenner C. Rice, Agu Pert

Journal:

Pharmacology Biochemistry and Behavior

Year:

1991

Language:

english

File:

PDF, 1.21 MB

english, 1991

94

Novel, long-acting and selective physostigmine analogues as potential therapeutics for Alzheimer's disease

Nigel H. Greig, Arnold Brossi, Timothy T. Soncrant, Harold W. Holloway, Xue Feng Pei, Stanley I. Rapoport, Donald K. Ingram

Journal:

Journal of Controlled Release

Year:

1994

Language:

english

File:

PDF, 81 KB

english, 1994

95

Neuroendocrine responses to intravenous infusion of arecoline in patients with Alzheimer's disease

Sanjay Asthana, Kathleen C. Raffaele, Nigel H. Greig, Annamaria Berardi, P. Pearse Morris, Mark B. Schapiro, Stanley I. Rapoport, Marc R. Blackman, Timothy T. Soncrant

Journal:

Psychoneuroendocrinology

Year:

1995

Language:

english

File:

PDF, 1.12 MB

english, 1995

96

Flexibility versus “rigidity” of the functional architecture of AChE active center

Avigdor Shafferman, Dov Barak, Dana Stein, Chanoch Kronman, Baruch Velan, Nigel H. Greig, Arie Ordentlich

Journal:

Chemico-Biological Interactions

Year:

2008

Language:

english

File:

PDF, 658 KB

english, 2008

97

Preferential enhancement of older human T cell cytokine generation, chemotaxis, proliferation and survival by lenalidomide

Mei-Chuan Huang, Nigel H. Greig, Weiming Luo, David Tweedie, Janice B. Schwartz, Dan L. Longo, Luigi Ferrucci, William B. Ershler, Edward J. Goetzl

Journal:

Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 776 KB

english, 2011

98

Intravenous butyrylcholinesterase administration and plasma and brain levels of cocaine and metabolites in rats

Gilberto N. Carmona, Charles W. Schindler, Nigel H. Greig, Harold W. Holloway, Rebecca A. Jufer, Edward J. Cone, David A. Gorelick

Journal:

European Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 111 KB

english, 2005

99

Pregabalin suppresses calcium-mediated proteolysis and improves stroke outcome

Jeong Seon Yoon, Jong-Hwan Lee, Tae Gen Son, Mohamed R. Mughal, Nigel H. Greig, Mark P. Mattson

Journal:

Neurobiology of Disease

Year:

2011

Language:

english

File:

PDF, 863 KB

english, 2011

100

Exendin-4 decreases amphetamine-induced locomotor activity

Kevin Erreger, Adeola R. Davis, Amanda M. Poe, Nigel H. Greig, Gregg D. Stanwood, Aurelio Galli

Journal:

Physiology & Behavior

Year:

2012

Language:

english

File:

PDF, 374 KB

english, 2012