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51

Identification of Unsafe Human Induced Pluripotent Stem Cell Lines Using a Robust Surrogate Assay for Pluripotency

Polanco, Juan Carlos, Ho, Mirabelle S.H., Wang, Bei, Zhou, Qi, Wolvetang, Ernst, Mason, Elizabeth, Wells, Christine A., Kolle, Gabriel, Grimmond, Sean M., Bertoncello, Ivan, O'Brien, Carmel, Laslett,

Journal:

Year:

2013

Language:

english

File:

PDF, 3.09 MB

english, 2013

52

Integration-Free Induced Pluripotent Stem Cells Model Genetic and Neural Developmental Features of Down Syndrome Etiology

Briggs, James A., Sun, Jane, Shepherd, Jill, Ovchinnikov, Dmitry A., Chung, Tung-Liang, Nayler, Sam P., Kao, Li-Pin, Morrow, Carl A., Thakar, Nilay Y., Soo, Set-Yen, Peura, Teija, Grimmond, Sean, Wolv

Journal:

Year:

2013

Language:

english

File:

PDF, 1.23 MB

english, 2013

53

Understanding pancreatic cancer genomes

Cowley, Mark J., Chang, David K., Pajic, Marina, Johns, Amber L., Waddell, Nicola, Grimmond, Sean M., Biankin, Andrew V.

Journal:

Journal of Hepato-Biliary-Pancreatic Sciences

Year:

2013

Language:

english

File:

PDF, 779 KB

english, 2013

54

Transcriptome content and dynamics at single-nucleotide resolution

Nicole Cloonan, Sean M Grimmond

Journal:

Year:

2008

Language:

english

File:

PDF, 124 KB

english, 2008

55

Mutations in DARS Cause Hypomyelination with Brain Stem and Spinal Cord Involvement and Leg Spasticity

Taft, Ryan J., Vanderver, Adeline, Leventer, Richard J., Damiani, Stephen A., Simons, Cas, Grimmond, Sean M., Miller, David, Schmidt, Johanna, Lockhart, Paul J., Pope, Kate, Ru, Kelin, Crawford, Joann

Journal:

The American Journal of Human Genetics

Year:

2013

Language:

english

File:

PDF, 644 KB

english, 2013

56

A De Novo Mutation in the β-Tubulin Gene TUBB4A Results in the Leukoencephalopathy Hypomyelination with Atrophy of the Basal Ganglia and Cerebellum

Simons, Cas, Wolf, Nicole I., McNeil, Nathan, Caldovic, Ljubica, Devaney, Joseph M., Takanohashi, Asako, Crawford, Joanna, Ru, Kelin, Grimmond, Sean M., Miller, David, Tonduti, Davide, Schmidt, Johann

Journal:

The American Journal of Human Genetics

Year:

2013

Language:

english

File:

PDF, 572 KB

english, 2013

57

Transcriptional switching in macrophages associated with the peritoneal foreign body response

Mooney, Jane E, Summers, Kim M, Gongora, Milena, Grimmond, Sean M, Campbell, Julie H, Hume, David A, Rolfe, Barbara E

Journal:

Immunology & Cell Biology

Year:

2014

Language:

english

File:

PDF, 794 KB

english, 2014

58

Mining the genomes of exceptional responders

Chang, David K., Grimmond, Sean M., Evans, T. R. Jeffry, Biankin, Andrew V.

Journal:

Nature Reviews Cancer

Year:

2014

Language:

english

File:

PDF, 575 KB

english, 2014

59

Identification of a Novel de Novo p.Phe932Ile KCNT1 Mutation in a Patient With Leukoencephalopathy and Severe Epilepsy

Vanderver, Adeline, Simons, Cas, Schmidt, Johanna L., Pearl, Philip L., Bloom, Miriam, Lavenstein, Bennett, Miller, David, Grimmond, Sean M., Taft, Ryan J.

Journal:

Pediatric Neurology

Year:

2014

Language:

english

File:

PDF, 906 KB

english, 2014

60

Obituary

Vanderver, Adeline, Simons, Cas, Schmidt, Johanna L., Pearl, Philip L., Bloom, Miriam, Lavenstein, Bennett, Miller, David, Grimmond, Sean M., Taft, Ryan J.

Journal:

Year:

1961

Language:

english

File:

PDF, 173 KB

english, 1961

61

Novel cancer drivers: mining the kinome

Andrew V Biankin,Sean M Grimmond

Journal:

Genome Medicine

Year:

2013

Language:

english

File:

PDF, 101 KB

english, 2013

62

Proteome adaptation in cell reprogramming proceeds via distinct transcriptional networks

Benevento, Marco, Tonge, Peter D., Puri, Mira C., Hussein, Samer M. I., Cloonan, Nicole, Wood, David L., Grimmond, Sean M., Nagy, Andras, Munoz, Javier, Heck, Albert J. R.

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 12.64 MB

english, 2014

63

Imperfect centered miRNA binding sites are common and can mediate repression of target mRNAs

Martin, Hilary C, Wani, Shivangi, Steptoe, Anita L, Krishnan, Keerthana, Nones, Katia, Nourbakhsh, Ehsan, Vlassov, Alexander, Grimmond, Sean M, Cloonan, Nicole

Journal:

Year:

2014

Language:

english

File:

PDF, 3.16 MB

english, 2014

64

BRCA1 and BRCA2 Missense Variants of High and Low Clinical Significance Influence Lymphoblastoid Cell Line Post-Irradiation Gene Expression

Waddell, Nic, Ten Haaf, Anette, Marsh, Anna, Johnson, Julie, Walker, Logan C., Investigators, kConFab, Gongora, Milena, Brown, Melissa, Grover, Piyush, Girolami, Mark, Grimmond, Sean, Chenevix-Trench,

Journal:

Year:

2008

Language:

english

File:

PDF, 217 KB

english, 2008

65

The Abundance of Short Proteins in the Mammalian Proteome

Frith, Martin C., Forrest, Alistair R., Nourbakhsh, Ehsan, Pang, Ken C., Kai, Chikatoshi, Kawai, Jun, Carninci, Piero, Hayashizaki, Yoshihide, Bailey, Timothy L., Grimmond, Sean M.

Journal:

Year:

2006

Language:

english

File:

PDF, 658 KB

english, 2006

66

Use of DNA–Damaging Agents and RNA Pooling to Assess Expression Profiles Associated with BRCA1 and BRCA2 Mutation Status in Familial Breast Cancer Patients

Walker, Logan C., Thompson, Bryony A., Waddell, Nic, Investigators, kConFab, Grimmond, Sean M., Spurdle, Amanda B., Stranger, Barbara E.

Journal:

Year:

2010

Language:

english

File:

PDF, 380 KB

english, 2010

67

The phospholipase C β3 gene located in the MEN1 region shows loss of expression in endocrine tumours

Weber, Günther, Friedman, Eitan, Grimmond, Sean, Hayward, Nicholas K., Phelan, Catherine, Skogseid, Britt, Gobl, Anders, Zedenius, Jan, Sandelin, Kerstin, Teh, Bin Tean, Carson, Emma, White, Irene, Öb

Journal:

Human Molecular Genetics

Year:

1994

Language:

english

File:

PDF, 3.91 MB

english, 1994

68

Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors

Ng, Preston S.K., Böhm, Raphael, Hartley-Tassell, Lauren E., Steen, Jason A., Wang, Hui, Lukowski, Samuel W., Hawthorne, Paula L., Trezise, Ann E.O., Coloe, Peter J., Grimmond, Sean M., Haselhorst, Th

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1.46 MB

english, 2014

69

Can we move towards personalised pancreatic cancer therapy?

Jamieson, Nigel Balfour, Chang, David K, Grimmond, Sean M, Biankin, Andrew V

Journal:

Expert Review of Gastroenterology and Hepatology

Year:

2014

Language:

english

File:

PDF, 464 KB

english, 2014

70

[IMPERIAL COLLEGE PRESS Proceedings of the 19th International Conference - Gold Coast, Queensland, Australia (1 – 3 December 2008)] Genome Informatics 2008 - SEQUENCING THE TRANSCRIPTOME IN TOTO

GRIMMOND, SEAN M.

Language:

english

File:

PDF, 66 KB

english

71

Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma

Feigin, Michael E, Garvin, Tyler, Bailey, Peter, Waddell, Nicola, Chang, David K, Kelley, David R, Shuai, Shimin, Gallinger, Steven, McPherson, John D, Grimmond, Sean M, Khurana, Ekta, Stein, Lincoln

Journal:

Nature Genetics

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

72

10. Clinicopathological features of HER2 amplified pancreatic cancer

Chou, Angela, Waddell, Nicola, Cowley, Mark J., Grimmond, Sean M., APGI,, Gill, Anthony J., Morey, Adrienne L., Biankin, Andrew V.

Journal:

Year:

2014

Language:

english

File:

PDF, 57 KB

english, 2014

73

9. Cyclin-Dependent kinase inhibitor as a potential novel therapeutic agent for pancreatic cancer

Chou, Angela, Gill, Anthony J., Kang, Jian, Lee, Christine, Sergio, Marcelo, APGI,, Musgrove, Liz, Morey, Adrienne L., Grimmond, Sean, Biankin, Andrew V., Pajic, Marina

Journal:

Year:

2014

Language:

english

File:

PDF, 43 KB

english, 2014

74

Telomere sequence content can be used to determine ALT activity in tumours

Lee, Michael, Teber, Erdahl T, Holmes, Oliver, Nones, Katia, Patch, Ann-Marie, Dagg, Rebecca A, Lau, Loretta M S, Lee, Joyce H, Napier, Christine E, Arthur, Jonathan W, Grimmond, Sean M, Hayward, Nich

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 699 KB

english, 2018

75

Transcriptome-Wide Prediction of miRNA Targets in Human and Mouse Using FASTH

Ragan, Chikako, Cloonan, Nicole, Grimmond, Sean M., Zuker, Michael, Ragan, Mark A., Patil, Christopher K.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.29 MB

english, 2009

76

A Continuum of Cell States Spans Pluripotency and Lineage Commitment in Human Embryonic Stem Cells

Hough, Shelley R., Laslett, Andrew L., Grimmond, Sean B., Kolle, Gabriel, Pera, Martin F., Reh, Thomas A.

Journal:

Year:

2009

Language:

english

File:

PDF, 459 KB

english, 2009

77

Profiling Gene Expression Induced by Protease-Activated Receptor 2 (PAR2) Activation in Human Kidney Cells

Suen, Jacky Y., Gardiner, Brooke, Grimmond, Sean, Fairlie, David P., Wu, Xiaolin

Journal:

Year:

2010

Language:

english

File:

PDF, 992 KB

english, 2010

78

Identification of Anchor Genes during Kidney Development Defines Ontological Relationships, Molecular Subcompartments and Regulatory Pathways

Thiagarajan, Rathi D., Georgas, Kylie M., Rumballe, Bree A., Lesieur, Emmanuelle, Chiu, Han Sheng, Taylor, Darrin, Tang, Dave T. P., Grimmond, Sean M., Little, Melissa H., Pera, Martin

Journal:

Year:

2011

Language:

english

File:

PDF, 982 KB

english, 2011

79

A High-Throughput Platform for Lentiviral Overexpression Screening of the Human ORFeome

Škalamera, Dubravka, Ranall, Max V., Wilson, Benjamin M., Leo, Paul, Purdon, Amy S., Hyde, Carolyn, Nourbakhsh, Ehsan, Grimmond, Sean M., Barry, Simon C., Gabrielli, Brian, Gonda, Thomas J., Jothi, Ra

Journal:

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

80

Phasevarion Mediated Epigenetic Gene Regulation in Helicobacter pylori

Srikhanta, Yogitha N., Gorrell, Rebecca J., Steen, Jason A., Gawthorne, Jayde A., Kwok, Terry, Grimmond, Sean M., Robins-Browne, Roy M., Jennings, Michael P., Bruggemann, Holger

Journal:

Year:

2011

Language:

english

File:

PDF, 341 KB

english, 2011

81

SnapShot-Seq: A Method for Extracting Genome-Wide, In Vivo mRNA Dynamics from a Single Total RNA Sample

Gray, Jesse M., Harmin, David A., Boswell, Sarah A., Cloonan, Nicole, Mullen, Thomas E., Ling, Joseph J., Miller, Nimrod, Kuersten, Scott, Ma, Yong-Chao, McCarroll, Steven A., Grimmond, Sean M., Sprin

Journal:

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

82

Rapid Identification of a Novel Complex I MT-ND3 m.10134C>A Mutation in a Leigh Syndrome Patient

Miller, David K., Menezes, Minal J., Simons, Cas, Riley, Lisa G., Cooper, Sandra T., Grimmond, Sean M., Thorburn, David R., Christodoulou, John, Taft, Ryan J., Whitworth, Alexander J.

Journal:

Year:

2014

Language:

english

File:

PDF, 431 KB

english, 2014

83

Platypus Induced Pluripotent Stem Cells: the Unique Pluripotency Signature of a Monotreme

Whitworth, Deanne Jeanette, Limnios, Ioannis J, Gauthier, Marie-Emilie, weeratunga, Prasanna, Ovchinnikov, Dmitry A., Baillie, Gregory, Grimmond, Sean M, Graves, Jennifer A.M., Wolvetang, Ernst Jurgen

Journal:

Stem Cells and Development

Year:

2018

Language:

english

File:

PDF, 2.14 MB

english, 2018

84

GUDMAP - An Online GenitoUrinary Resource

Armit, Chris, Harding, Simon, Davies, Jamie, Armstrong, Jane, Brennan, Jane, Lloyd-MacGilp, Sue, Houghton, Derek, Sharghi, Mehran, Pi, Xingjun, Cheng, Y., Aronow, Bruce, Gaido, Kevin, Grimmond, Sean,

Journal:

Bioentrepreneur

Year:

2009

Language:

english

File:

PDF, 2.48 MB

english, 2009

85

GUDMAP - An Online GenitoUrinary Resource

Armit, Chris, Harding, Simon, Davies, Jamie, Armstrong, Jane, Brennan, Jane, Lloyd-MacGilp, Sue, Houghton, Derek, Sharghi, Mehran, Pi, Xingjun, Cheng, Y., Aronow, Bruce, Gaido, Kevin, Grimmond, Sean,

Journal:

Bioentrepreneur

Year:

2009

File:

PDF, 2.48 MB

2009

86

Inotuzumab ozogamicin resistance associated with a novel CD22 truncating mutation in a case of Bâacute lymphoblastic leukaemia

Ryland, Georgina L., Barraclough, Allison, Fong, Chun Yew, Fleming, Shaun, Bajel, Ashish, Hofmann, Oliver, Westerman, David, Grimmond, Sean, Blombery, Piers

Journal:

British Journal of Haematology

Year:

2020

File:

PDF, 141 KB

2020

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