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51

Axially Chiral N -Benzyl- N ,7-dimethyl-5-phenyl-1,7-naphthyridine-6-carboxamide Derivatives as Tachykinin NK 1 Receptor Antagonists: Determination of the Absolute Stereochemical Requirements

Ikeura, Yoshinori, Ishichi, Yuji, Tanaka, Toshimasa, Fujishima, Akira, Murabayashi, Mika, Kawada, Mitsuru, Ishimaru, Takenori, Kamo, Izumi, Doi, Takayuki, Natsugari, Hideaki

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 183 KB

english, 1998

52

Synthesis of 5,6-cis-carbapenems related to C-19393 H2

Natsugari, Hideaki, Matsushita, Yoshihiro, Tamura, Norikazu, Yoshioka, Kouichi, Ochiai, Michihiko

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1983

Language:

english

File:

PDF, 1.22 MB

english, 1983

53

Synthesis of lactivicin and its derivatives

Natsugari, Hideaki, Kawano, Yasuhiko, Morimoto, Akira, Yoshioka, Kouichi, Ochiai, Michihiko

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1987

Language:

english

File:

PDF, 205 KB

english, 1987

54

Synthesis of ?-lactam analogues of carbapenems with substituted-thio groups at the C-3 position

Hashiguchi, Shohei, Natsugari, Hideaki, Ochiai, Michihiko

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1988

Language:

english

File:

PDF, 1008 KB

english, 1988

55

Solid-phase synthesis of photoaffinity probes: highly efficient incorporation of biotin-tag and cross-linking groups

Kan, Toshiyuki, Tominari, Yusuke, Morohashi, Yuichi, Natsugari, Hideaki, Tomita, Taisuke, Iwatsubo, Takeshi, Fukuyama, Tohru

Journal:

Chemical Communications

Year:

2003

Language:

english

File:

PDF, 202 KB

english, 2003

56

Enantioselective synthesis of an axially chiral 1,7-naphthyridine-6-carboxamide derivative having potent antagonist activity at the NK1 receptor

Ikeura, Yoshinori, Doi, Takayuki, Fujishima, Akira, Natsugari, Hideaki

Journal:

Chemical Communications

Year:

1998

Language:

english

File:

PDF, 70 KB

english, 1998

57

Conformation and Atropisomeric Properties of Indometacin Derivatives

Wakamatsu, Shintaro, Takahashi, Yuka, Tabata, Hidetsugu, Oshitari, Tetsuta, Tani, Norihiko, Azumaya, Isao, Katsumoto, Yukiteru, Tanaka, Takeyuki, Hosoi, Shinzo, Natsugari, Hideaki, Takahashi, Hideyo

Journal:

Chemistry - A European Journal

Year:

2013

Language:

english

File:

PDF, 1.04 MB

english, 2013

58

Caenorhabditis elegans galectins LEC-6 and LEC-1 recognize a chemically synthesized Gal 1-4Fuc disaccharide unit which is present in Protostomia glycoconjugates

Takeuchi, T., Nishiyama, K., Sugiura, K.-i., Takahashi, M., Yamada, A., Kobayashi, S., Takahashi, H., Natsugari, H., Kasai, K.-i.

Journal:

Year:

2009

Language:

english

File:

PDF, 620 KB

english, 2009

59

N -Benzoyl-1,5-benzothiazepine and Its S -Oxide as Vasopressin Receptor Ligands: Insight into the Active Stereochemistry around the Seven-Membered Ring

Yoneda, Tetsuya, Tabata, Hidetsugu, Tasaka, Tomohiko, Oshitari, Tetsuta, Takahashi, Hideyo, Natsugari, Hideaki

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 988 KB

english, 2015

60

Development of fluorous lipid-based nanobubbles for efficiently containing perfluoropropane

Oda, Yusuke, Suzuki, Ryo, Mori, Tatsuya, Takahashi, Hideyo, Natsugari, Hideaki, Omata, Daiki, Unga, Johan, Uruga, Hitoshi, Sugii, Mutsumi, Kawakami, Shigeru, Higuchi, Yuriko, Yamashita, Fumiyoshi, Has

Journal:

International Journal of Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 929 KB

english, 2015

61

Purification of galectin-1 mutants using an immobilized Galactoseβ1–4Fucose affinity adsorbent

Takeuchi, Tomoharu, Tamura, Mayumi, Ishii, Nobuaki, Ishikida, Hiroki, Sugimoto, Saori, Suzuki, Daichi, Nishiyama, Kazusa, Takahashi, Hideyo, Natsugari, Hideaki, Arata, Yoichiro

Journal:

Protein Expression and Purification

Year:

2015

Language:

english

File:

PDF, 590 KB

english, 2015

62

Sulindac Sulfide Is a Noncompetitive -Secretase Inhibitor That Preferentially Reduces A 42 Generation

Takahashi, Y., Hayashi, I., Tominari, Y., Rikimaru, K., Morohashi, Y., Kan, T., Natsugari, H., Fukuyama, T., Tomita, T., Iwatsubo, T.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 738 KB

english, 2003

63

Preparation of a polyclonal antibody that recognizes a unique galactoseβ1-4fucose disaccharide epitope

Takeuchi, Tomoharu, Nishiyama, Kazusa, Saito, Saori, Tamura, Mayumi, Fuwa, Takashi J., Nishihara, Shoko, Takahashi, Hideyo, Natsugari, Hideaki, Arata, Yoichiro, Kasai, Ken-ichi

Journal:

Carbohydrate Research

Year:

2015

Language:

english

File:

PDF, 756 KB

english, 2015

64

Stereochemical properties of N-benzoylated carbazole derivatives

Kayama, Susumu, Tabata, Hidetsugu, Takahashi, Yuka, Tani, Norihiko, Wakamatsu, Shintaro, Oshitari, Tetsuta, Natsugari, Hideaki, Takahashi, Hideyo

Journal:

Year:

2015

Language:

english

File:

PDF, 1.68 MB

english, 2015

65

Novel Glycosidation of α-d-Altropyranosides

Nakayama, Takahiro, Nishiyama, Kazusa, Natsugari, Hideaki, Takahashi, Hideyo

Journal:

Year:

2010

Language:

english

File:

PDF, 125 KB

english, 2010

66

Intramolecular Nucleophilic Aromatic Substitution Reaction of 2-Carboxamido-3-arylquinazolin-4-ones and its Application to the Synthesis of Secondary Aryl Amines

Fuwa, Haruhiko, Kobayashi, Toshitake, Tokitoh, Takashi, Torii, Yukiko, Natsugari, Hideaki

Journal:

Year:

2004

Language:

english

File:

PDF, 149 KB

english, 2004

67

Photoaffinity Probes for Alzheimer’s Disease

Kan, T., Kita, Y., Morohashi, Y., Tominari, Y., Hosoda, S., Tomita, T., Natsugari, H., Iwatsubo, T., Fukuyama, T.

Journal:

Year:

2007

Language:

english

File:

PDF, 98 KB

english, 2007

68

Baker's Yeast Reduction of N -Protected Methyl 4-Amino-3-oxobutanoates and 3-oxopentanoates

Hashiguchi, Shohei, Kawada, Akira, Natsugari, Hideaki

Journal:

Year:

1992

File:

PDF, 538 KB

1992

69

Isolation of Atropisomers of N-Benzoylated Pyrroles and Imidazoles

Takahashi, Yuka, Wakamatsu, Shintaro, Tabata, Hidetsugu, Oshitari, Tetsuta, Natsugari, Hideaki, Takahashi, Hideyo

Journal:

Year:

2015

Language:

english

File:

PDF, 173 KB

english, 2015

70

Synthesis of Ether-Linked Sugar by Nucleophilic Opening of Carbohydrate Oxiranes

Nishiyama, Kazusa, Nakayama, Takahiro, Natsugari, Hideaki, Takahashi, Hideyo

Journal:

Year:

2008

Language:

english

File:

PDF, 152 KB

english, 2008

71

Freezing the Butterfly Motion of Carbamazepine Derivatives

Kanase, Yuki, Kuniyoshi, Mai, Tabata, Hidetsugu, Takahashi, Yuka, Kayama, Susumu, Wakamatsu, Shintaro, Oshitari, Tetsuta, Natsugari, Hideaki, Takahashi, Hideyo

Journal:

Year:

2015

Language:

english

File:

PDF, 907 KB

english, 2015

72

Stereochemistry of N-Benzoyl-5-substituted-1-benzazepines Revisited: Synthesis of the Conformationally Biased Derivatives and Revision of the Reported Structure

Tabata, Hidetsugu, Yoneda, Tetsuya, Tasaka, Tomohiko, Ito, Shigekazu, Oshitari, Tetsuta, Takahashi, Hideyo, Natsugari, Hideaki

Journal:

Journal of Organic Chemistry

Year:

2016

Language:

english

File:

PDF, 806 KB

english, 2016

73

Electronic effects on the amide E-/Z-preference of N-benzoyl-carbazole derivatives

Kayama, Susumu, Tani, Norihiko, Tabata, Hidetsugu, Oshitari, Tetsuta, Natsugari, Hideaki, Takahashi, Hideyo

Journal:

Tetrahedron Letters

Year:

2016

Language:

english

File:

PDF, 662 KB

english, 2016

74

Further Studies on Stereoselective Synthesis of Vicinal Diamines from 3,6-Dihydrothiazine-1-imines

M. Weinreb, Steven, Natsugari, Hideaki, Turos, Edward, J. Cvetovich, Raymond

Journal:

Year:

1987

Language:

english

File:

PDF, 127 KB

english, 1987

75

ChemInform Abstract: Synthesis of Lactivicin and Its Derivatives.

NATSUGARI, H., KAWANO, Y., MORIMOTO, A., YOSHIOKA, K., OCHIAI, M.

Journal:

Year:

1987

File:

PDF, 183 KB

1987

76

ChemInform Abstract: Synthesis of γ-Lactam Analogues of Carbapenems with Substituted Thio Groups at the C-3 Position.

HASHIGUCHI, S., NATSUGARI, H., OCHIAI, M.

Journal:

Year:

1988

File:

PDF, 226 KB

1988

77

ChemInform Abstract: Further Studies on Stereoselective Synthesis of Vicinal Diamines from 3,6-Dihydrothiazine-1-imines.

NATSUGARI, H., TUROS, E., WEINREB, S. M., CVETOVICH, R. J.

Journal:

Year:

1987

File:

PDF, 216 KB

1987

78

ChemInform Abstract: Synthesis of Carbapenems with a Sulfonyl Group in the C-6 Side-Chain and Their Biological Activity.

TAMURA, N., NATSUGARI, H., KAWANO, Y., MATSUSHITA, Y., YOSHIOKA, K., OCHIAI, M.

Journal:

Year:

1987

File:

PDF, 79 KB

1987

79

Polyacrylamide-based Functional Polymer-immobilized Perruthenate for Aerobic Alcohol Oxidation

Hamamoto, Hiromi, Kudoh, Masahiro, Takahashi, Hideyo, Natsugari, Hideaki, Ikegami, Shiro

Journal:

Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 77 KB

english, 2007

80

Diastereoselective Synthesis of Atropisomeric 3-(2-Substituted Aryl)quinazolin-4-ones and Their Stereochemical Properties

Natsugari, Hideaki, Tokitoh, Takashi, Kobayashi, Toshitake, Nakada, Eisuke, Inoue, Tohru, Yokoshima, Satoshi, Takahashi, Hideyo

Journal:

Year:

2006

Language:

english

File:

PDF, 276 KB

english, 2006

81

Sugar-Binding Properties of the Two Lectin Domains of LEC-1 with Respect to the Galβ1-4Fuc Disaccharide Unit Present in Protostomia Glycoconjugates

Takeuchi, Tomoharu, Sugiura, Ken-ichi, Nishiyama, Kazusa, Takahashi, Hideyo, Natsugari, Hideaki, Arata, Yoichiro, Kasai, Ken-ichi

Journal:

Biological & Pharmaceutical Bulletin

Year:

2011

Language:

english

File:

PDF, 622 KB

english, 2011

82

Heterocycles. IV. Reactions of 2-Amino-3H-1, 4-benzodiazepines with Primary Amines and Hydroxylamines

MEGURO, KANJI, NATSUGARI, HIDEAKA, TAWADA, HIROYUKI, KUWADA, YUTAKA

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1973

File:

PDF, 1017 KB

1973

83

Heterocycles. XIV. Reactions of 2-amino-5-phenyl-1,4-benzodiazepines and 2-amino-6-phenyl-1,5-benzodiazocines with diketene.

NATSUGARI, HIDEAKI, MEGURO, KANJI, KUWADA, YUTAKA

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1979

File:

PDF, 1.07 MB

1979

84

Heterocycles. XIII. Reactions of 2-amino-1,4-benzodiazepine 1-oxides and 2-amino-1,5-benzodiazocine 1-oxides with acetylenecarboxylates.

NATSUGARI, HIDEAKI, KUWADA, YUTAKA

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1979

File:

PDF, 805 KB

1979

85

Heterocycles. XI. Synthesis of 2-amino-6-phenyl-3,4-dihydro-1,5-benzodiazocines.

NATSUGARI, HIDEAKI, MEGURO, KANJI, KUWADA, YUTAKA

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1979

File:

PDF, 727 KB

1979

86

Heterocycles. XII. Synthesis of 2-amino-5-phenyl-1,4-benzodiazepine 1-oxides and 2-amino-6-phenyl-1,5-benzodiazocine 1-oxides and their reactions with acylating agents.

NATSUGARI, HIDEAKI, MEGURO, KANJI, KUWADA, YUTAKA

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1979

File:

PDF, 917 KB

1979

87

Chemistry and Anti-tumor Activity of Sperabillin Polymers.

HIDA, Tsuneaki, TSUBOTANI, Shigetoshi, HORI, Akira, MURAKAMI, Morio, NATSUGARI, Hideaki, KOZAI, Yoshio, HARADA, Setsuo

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1993

File:

PDF, 743 KB

1993

88

Synthesis of 3-Ureido Derivatives of Coumarin and 2-Quinolone as Potent Acyl-CoA: Cholesterol Acyltransferase Inhibitors.

TAWADA, Hiroyuki, NATSUGARI, Hideaki, ISHIKAWA, Eiichiro, SUGIYAMA, Yasuo, IKEDA, Hitoshi, MEGURO, Kanji

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1995

File:

PDF, 1.25 MB

1995

89

Potent NK1 Receptor Antagonists: Synthesis and Antagonistic Activity of Various Heterocycles with an N-(3,5-Bis(trifluoromethyl)benzyl)-N-methylcarbamoyl Substituent.

IKEURA, Yoshinori, TANAKA, Toshimasa, KIYOTA, Yutaka, MORIMOTO, Shinji, OGINO, Masaki, ISHIMARU, Takenori, KAMO, Izumi, DOI, Takayuki, NATSUGARI, Hideaki

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1997

File:

PDF, 1.55 MB

1997

90

Synthesis of New Galβ1→4Fuc Segments Useful for Biological Investigations

Nishiyama, Kazusa, Yamada, Atsushi, Takeuchi, Tomoharu, Arata, Yoichiro, Kasai, Ken-ichi, Oshitari, Tetsuta, Natsugari, Hideaki, Takahashi, Hideyo

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2011

Language:

english

File:

PDF, 613 KB

english, 2011

91

Synthesis of Fluorescence-Labeled Galβ1-3Fuc and Galβ1-4Fuc as Probes for the Endogenous Glyco-Epitope Recognized by Galectins in Caenorhabditis elegans

Nishiyama, Kazusa, Yamada, Atsushi, Takahashi, Miki, Takeuchi, Tomoharu, Kasai, Ken-ichi, Kobayashi, Susumu, Natsugari, Hideaki, Takahashi, Hideyo

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2010

Language:

english

File:

PDF, 483 KB

english, 2010

92

Crystallization-Induced Diastereomeric Transformation of N-2′-t-Butyl-6′-iodobenzoyl-3-bromocarbazole

Kayama, Susumu, Tani, Norihiko, Takahashi, Yuka, Tabata, Hidetsugu, Wakamatsu, Shintaro, Oshitari, Tetsuta, Natsugari, Hideaki, Takahashi, Hideyo

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2014

Language:

english

File:

PDF, 545 KB

english, 2014

93

Leaching of the Plasticizer, Acetyl Tributyl Citrate: (ATBC) from Plastic Kitchen Wrap

Nara, Kenichi, Nishiyama, Kazusa, Natsugari, Hideaki, Takeshita, Akira, Takahashi, Hideyo

Journal:

JOURNAL OF HEALTH SCIENCE

Year:

2009

Language:

english

File:

PDF, 84 KB

english, 2009

94

Development of a Therapeutic Agent for Menkes Disease: Solubilization of a Copper-Disulfiram Complex

Hoshi, Yujiro, Tani, Norihiko, Tabata, Hidetsugu, Wakamatsu, Shintaro, Munakata, Mitsutoshi, Maruyama, Kazuo, Kodama, Hiroko, Oshitari, Tetsuta, Natsugari, Hideaki, Takahashi, Hideyo

Journal:

YAKUGAKU ZASSHI

Year:

2015

File:

PDF, 775 KB

2015

95

Synthesis and structure-activity relationships of carbapenems related to C-19393 H2.

NATSUGARI, HIDEAKI, MATSUSHITA, YOSHIHIRO, TAMURA, NORIKAZU, YOSHIOKA, KOUICHI, KONDO, MASAHIRO, OKONOGI, KENJI, KUNO, MITSUZO, OCHIAI, MICHIHIKO

Journal:

The Journal of Antibiotics

Year:

1983

Language:

english

File:

PDF, 9.20 MB

english, 1983

96

Synthesis and antimicrobial activity of sperabillin derivatives.

HIDA, TSUNEAKI, TSUBOTANI, SHIGETOSHI, KATAYAMA, NOZOMI, FUNABASHI, YASUNORI, NATSUGARI, HIDEAKI, HARADA, SETSUO

Journal:

The Journal of Antibiotics

Year:

1993

Language:

english

File:

PDF, 614 KB

english, 1993

97

The DC2.3 Gene in Caenorhabditis elegans Encodes a Galectin That Recognizes the Galactoseβ1→4Fucose Disaccharide Unit

Nemoto-Sasaki, Yoko, Takai, Shunsuke, Takeuchi, Tomoharu, Arata, Yoichiro, Nishiyama, Kazusa, Yamada, Atsushi, Takahashi, Hideyo, Natsugari, Hideaki, Kasai, Ken-ichi

Journal:

Biological & Pharmaceutical Bulletin

Year:

2011

Language:

english

File:

PDF, 959 KB

english, 2011

98

Heterocycles. X. Synthesis and reactions of 1,4,5-benzotriazocinium salts.

NATSUGARI, HIDEAKI, MEGURO, KANJI, KUWADA, YUTAKA

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1979

File:

PDF, 864 KB

1979

99

Synthesis of carbapenems with a sulfonyl group in the C-6 side-chain and their biological activity.

TAMURA, NORIKAZU, NATSUGARI, HIDEAKI, KAWANO, YASUHIKO, MATSUSHITA, YOSHIHIRO, YOSHIOKA, KOUICHI, OCHIAI, MICHIHIKO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 2.92 MB

english, 1987

100

β-Galactosidases from Jack Bean and Streptococcus Have Different Cleaving Abilities towards Fucose-Containing Sugars

Takeuchi, Tomoharu, Sugiura, Ken-ichi, Nishiyama, Kazusa, Takahashi, Hideyo, Natsugari, Hideaki, Arata, Yoichiro, Natsuka, Shunji, Kasai, Ken-ichi

Journal:

Biological & Pharmaceutical Bulletin

Year:

2011

Language:

english

File:

PDF, 545 KB

english, 2011