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51

The anti-inflammatory effect of lycopene complements the antioxidant action of ascorbic acid and α-tocopherol

Merel Hazewindus, Guido R.M.M. Haenen, Antje R. Weseler, Aalt Bast

Journal:

Year:

2012

Language:

english

File:

PDF, 353 KB

english, 2012

52

Evaluation of the accuracy of antioxidant competition assays: incorrect assumptions with major impact

Jiska M. Balk, Aalt Bast, Guido R.M.M. Haenen

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 890 KB

english, 2009

53

Characterization of the glutathione conjugate of the semisynthetic flavonoid monoHER

Hilde Jacobs, Wim J.F. van der Vijgh, Ger H. Koek, Guy J.J. Draaisma, Mohamed Moalin, Gino P.F. van Strijdonck, Aalt Bast, Guido R.M.M. Haenen

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 723 KB

english, 2009

54

An essential difference in the reactivity of the glutathione adducts of the structurally closely related flavonoids monoHER and quercetin

Hilde Jacobs, Mohamed Moalin, Marike W. van Gisbergen, Aalt Bast, Wim J.F. van der Vijgh, Guido R.M.M. Haenen

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 558 KB

english, 2011

55

Bioavailability of ferulic acid is determined by its bioaccessibility

Nuria Mateo Anson, Robin van den Berg, Rob Havenaar, Aalt Bast, Guido R.M.M. Haenen

Journal:

Journal of Cereal Science

Year:

2009

Language:

english

File:

PDF, 176 KB

english, 2009

56

Antioxidant and anti-inflammatory capacity of bioaccessible compounds from wheat fractions after gastrointestinal digestion

Nuria Mateo Anson, Robert Havenaar, Aalt Bast, Guido R.M.M. Haenen

Journal:

Journal of Cereal Science

Year:

2010

Language:

english

File:

PDF, 213 KB

english, 2010

57

Incomplete protection of genetic integrity of mature spermatozoa against oxidative stress

Joost O. Linschooten, Julian Laubenthal, Eduardo Cemeli, Adolf Baumgartner, Diana Anderson, Ville E. Sipinen, Gunnar Brunborg, Guido R.M.M. Haenen, Eleni Fthenou, Jacob J. Briedé, Frederik J. van Scho

Journal:

Reproductive Toxicology

Year:

2011

Language:

english

File:

PDF, 386 KB

english, 2011

58

Lecithinized copper,zinc-superoxide dismutase as a protector against doxorubicin-induced cardiotoxicity in mice

Gertjan J.M den Hartog, Guido R.M.M Haenen, Epie Boven, Wim J.F van der Vijgh, Aalt Bast

Journal:

Toxicology and Applied Pharmacology

Year:

2004

Language:

english

File:

PDF, 422 KB

english, 2004

59

The quercetin paradox

Agnes W. Boots, Hui Li, Roel P.F. Schins, Rodger Duffin, Johan W.M. Heemskerk, Aalt Bast, Guido R.M.M. Haenen

Journal:

Toxicology and Applied Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.30 MB

english, 2007

60

No reduction of α-tocopherol quinone by glutathione in rat liver microsomes

Rachel I.M van Haaften, Chris T.A Evelo, Guido R.M.M Haenen, Aalt Bast

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 136 KB

english, 2001

61

Tyrosine as important contributor to the antioxidant capacity of seminal plasma

Floris W.P.C. van Overveld, Guido R.M.M. Haenen, Johann Rhemrev, Jan P.W. Vermeiden, Aalt Bast

Journal:

Chemico-Biological Interactions

Year:

2000

Language:

english

File:

PDF, 108 KB

english, 2000

62

Hypochlorous acid is a potent inhibitor of GST P1-1

Rachel I.M van Haaften, Gertjan J.M den Hartog, Chris T.A Evelo, Guido R.M.M Haenen, Aalt Bast

Journal:

Chemico-Biological Interactions

Year:

2001

Language:

english

File:

PDF, 84 KB

english, 2001

63

Superoxide dismutase: the balance between prevention and induction of oxidative damage

Gertjan J.M den Hartog, Guido R.M.M Haenen, Erik Vegt, Wim J.F van der Vijgh, Aalt Bast

Journal:

Chemico-Biological Interactions

Year:

2003

Language:

english

File:

PDF, 147 KB

english, 2003

64

Inhibition of human glutathione S-transferase P1-1 by tocopherols and α-tocopherol derivatives

Rachel I.M. Van Haaften, Chris T.A. Evelo, John Penders, Miguel P.F. Eijnwachter, Guido R.M.M. Haenen, Aalt Bast

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

2001

Language:

english

File:

PDF, 265 KB

english, 2001

65

The pharmacology of the antioxidant lipoic acid

Gerreke Ph. Biewenga, Guido R.M.M. Haenen, Aalt Bast

Journal:

General Pharmacology: The Vascular System

Year:

1997

Language:

english

File:

PDF, 1.79 MB

english, 1997

66

New synthetic flavonoids as potent protectors against doxorubicin-induced cardiotoxicity

Frédérique A.A van Acker, Janneke W Hulshof, Guido R.M.M Haenen, Wiro M.P.B Menge, Wim J.F van der Vijgh, Aalt Bast

Journal:

Free Radical Biology and Medicine

Year:

2001

Language:

english

File:

PDF, 146 KB

english, 2001

67

Systemic poly(ADP-ribose) polymerase-1 activation, chronic inflammation, and oxidative stress in COPD patients

Geja J Hageman, Ingrid Larik, Herman-Jan Pennings, Guido R.M.M Haenen, Emiel F.M Wouters, Aalt Bast

Journal:

Free Radical Biology and Medicine

Year:

2003

Language:

english

File:

PDF, 183 KB

english, 2003

68

Competition between Ascorbate and Glutathione for the Oxidized Form of Methylated Quercetin Metabolites and Analogues: Tamarixetin, 4′O-Methylquercetin, Has the Lowest Thiol Reactivity

Moalin, Mohamed, van Strijdonck, Gino P. F., Bast, Aalt, Haenen, Guido R. M. M.

Journal:

Journal of Agricultural and Food Chemistry

Year:

2012

Language:

english

File:

PDF, 2.36 MB

english, 2012

69

Peroxynitrite Scavenging by Flavonoids

Guido R.M.M. Haenen, Jos B.G. Paquay, Ronald E.M. Korthouwer, Aalt Bast

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 113 KB

english, 1997

70

α-Tocopherol Inhibits Human Glutathione S-Transferase π

Rachel I.M. van Haaften, Chris T.A. Evelo, Guido R.M.M. Haenen, Aalt Bast

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 56 KB

english, 2001

71

4-Hydroxy-2,3-trans-nonenal stimulates microsomal lipid peroxidation by reducing the glutathione-dependent protection

Guido R.M.M. Haenen, Jacintha N.L. Tai Tin Tsoi, Nico P.E. Vermeulen, Henk Timmerman, Aalt Bast

Journal:

Archives of Biochemistry and Biophysics

Year:

1987

Language:

english

File:

PDF, 628 KB

english, 1987

72

Activation of the microsomal glutathione S-transferase by metabolites of α-methyldopa

Guido R.M.M. Haenen, Frank P. Jansen, Nico P.E. Vermeulen, Aalt Bast

Journal:

Archives of Biochemistry and Biophysics

Year:

1991

Language:

english

File:

PDF, 584 KB

english, 1991

73

Activation of the microsomal glutathione-s-transferase and reduction of the glutathione dependent protection against lipid peroxidation by acrolein

Guido R.M.M. Haenen, Nico P.E. Vermeulen, Jacintha N.L. Tai Tin Tsoi, Henri M.N. Ragetli, Henk Timmerman, Aalt Bast

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 716 KB

english, 1988

74

Scavenging of hypochlorous acid by lipoic acid

Guido R.M.M. Haenen, Aalt Bast

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 431 KB

english, 1991

75

Reduction of lipoic acid by lipoamide dehydrogenase

Gerreke Ph. Biewenga, Marco A. Dorstijn, Justus V. Verhagen, Guido R.M.M. Haenen, Aalt Bast

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 729 KB

english, 1996

76

Protection against lipid peroxidation by a microsomal glutathione-dependent labile factor

Guido R.M.M. Haenen, Aalt Bast

Journal:

Year:

1983

Language:

english

File:

PDF, 481 KB

english, 1983

77

Stability of blood (pro)vitamins during four years of storage at −20 °C: Consequences for epidemiologic research

Marga C. Ocké, Jaap Schrijver, Gatske L. Obermann-De Boer, Bennie P.M. Bloemberg, Guido R.M.M. Haenen, Daan Kromhout

Journal:

Journal of Clinical Epidemiology

Year:

1995

Language:

english

File:

PDF, 827 KB

english, 1995

78

The extraordinary antioxidant activity of vitamin E phosphate

Bashir M Rezk, Guido R.M.M Haenen, Wim J.F van der Vijgh, Aalt Bast

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2004

Language:

english

File:

PDF, 245 KB

english, 2004

79

The reversibility of the glutathionyl-quercetin adduct spreads oxidized quercetin-induced toxicity

Agnes W. Boots, Jiska M. Balk, Aalt Bast, Guido R.M.M. Haenen

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 228 KB

english, 2005

80

Prevention of a systematic underestimation of antioxidant activity in competition assays. The impact of unspecific reactions of the reactive species

Christiaan P. Beljaars, Jiska M. Balk, Aalt Bast, Guido R.M.M. Haenen

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 238 KB

english, 2010

81

Structure and activity in assessing antioxidant activity in vitro and in vivo: A critical appraisal illustrated with the flavonoids

Guido R.M.M. Haenen, Mariken J.T.J. Arts, Aalt Bast, Michael D. Coleman

Journal:

Environmental Toxicology and Pharmacology

Year:

2006

Language:

english

File:

PDF, 207 KB

english, 2006

82

Antioxidant capacity of reaction products limits the applicability of the Trolox Equivalent Antioxidant Capacity (TEAC) assay

Mariken J.T.J Arts, Guido R.M.M Haenen, Hans-Peter Voss, Aalt Bast

Journal:

Food and Chemical Toxicology

Year:

2004

Language:

english

File:

PDF, 208 KB

english, 2004

83

No role of DT-diaphorase (NQO1) in the protection against oxidized quercetin

Agnes W. Boots, Aalt Bast, Guido R.M.M. Haenen

Journal:

Year:

2005

Language:

english

File:

PDF, 185 KB

english, 2005

84

Dry-fractionation of wheat bran increases the bioaccessibility of phenolic acids in breads made from processed bran fractions

Youna M. Hemery, Nuria Mateo Anson, Rob Havenaar, Guido R.M.M. Haenen, Martijn W.J. Noort, Xavier Rouau

Journal:

Food Research International

Year:

2010

Language:

english

File:

PDF, 325 KB

english, 2010

85

Altered antioxidant status in peripheral skeletal muscle of patients with COPD

Harry R. Gosker, Aalt Bast, Guido R.M.M. Haenen, Marc A.J.G. Fischer, Ger J. van der Vusse, Emiel F.M. Wouters, Annemie M.W.J. Schols

Journal:

Respiratory Medicine

Year:

2005

Language:

english

File:

PDF, 238 KB

english, 2005

86

Antioxidant status associated with inflammation in sarcoidosis: A potential role for antioxidants

Agnes W. Boots, Marjolein Drent, Els L.R. Swennen, Harald J.J. Moonen, Aalt Bast, Guido R.M.M. Haenen

Journal:

Respiratory Medicine

Year:

2009

Language:

english

File:

PDF, 287 KB

english, 2009

87

Cereal grains for nutrition and health benefits: Overview of results from in vitro, animal and human studies in the HEALTHGRAIN project

Inger Björck, Elin Östman, Mette Kristensen, Nuria Mateo Anson, Ruth K. Price, Guido R.M.M. Haenen, Rob Havenaar, Knud Erik Bach Knudsen, Anders Frid, Hannu Mykkänen, Rob W. Welch, Gabriele Riccardi

Journal:

Trends in Food Science & Technology

Year:

2012

Language:

english

File:

PDF, 559 KB

english, 2012

88

Lipid Peroxidation Product 4-Hydroxynonenal Contributes to Bladder Smooth Muscle Damage

Rik de Jongh, Guido R.M.M. Haenen, Gommert A. van Koeveringe, Miriam Dambros, Philip E.V. van Kerrebroeck

Journal:

Year:

2008

Language:

english

File:

PDF, 250 KB

english, 2008

89

The antioxidant activity of phloretin: the disclosure of a new antioxidant pharmacophore in flavonoids

Bashir M Rezk, Guido R.M.M Haenen, Wim J.F van der Vijgh, Aalt Bast

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 123 KB

english, 2002

90

Oxidized quercetin reacts with thiols rather than with ascorbate: implication for quercetin supplementation

Agnes W Boots, Nard Kubben, Guido R.M.M Haenen, Aalt Bast

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 239 KB

english, 2003

91

Flavonoids can replace α-tocopherol as an antioxidant

Frédérique A.A. van Acker, Olga Schouten, Guido R.M.M. Haenen, Wim J.F. van der Vijgh, Aalt Bast

Journal:

Year:

2000

Language:

english

File:

PDF, 92 KB

english, 2000

92

Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identification of the antioxidant pharmacophore

Bashir M Rezk, Guido R.M.M Haenen, Wim J.F van der Vijgh, Aalt Bast

Journal:

Year:

2003

Language:

english

File:

PDF, 131 KB

english, 2003

93

Biomarkers

Helen R. Griffiths, Lennart Møller, Grzegorz Bartosz, Aalt Bast, Carlo Bertoni-Freddari, Andrew Collins, Marcus Cooke, Stefan Coolen, Guido Haenen, Anne-Mette Hoberg, Steffen Loft, Joe Lunec, Ryszard

Journal:

Molecular Aspects of Medicine

Year:

2002

Language:

english

File:

PDF, 983 KB

english, 2002

94

Inhibition of various glutathione S-transferase isoenzymes by RRR-α-tocopherol

Rachel I.M. van Haaften, Guido R.M.M. Haenen, Peter J. van Bladeren, Jan J.P. Bogaards, Chris T.A. Evelo, Aalt Bast

Journal:

Toxicology in Vitro

Year:

2003

Language:

english

File:

PDF, 177 KB

english, 2003

95

Peroxynitrite scavenging of flavonoids: structure activity relationship

Chantal G.M Heijnen, Guido R.M.M Haenen, Jef A.J.M Vekemans, Aalt Bast

Journal:

Environmental Toxicology and Pharmacology

Year:

2001

Language:

english

File:

PDF, 173 KB

english, 2001

96

Nuclear factor-κB activation is higher in peripheral blood mononuclear cells of male smokers

Robin van den Berg, Guido R.M.M Haenen, Henk van den Berg, Aalt Bast

Journal:

Environmental Toxicology and Pharmacology

Year:

2001

Language:

english

File:

PDF, 84 KB

english, 2001

97

Contribution of 4-hydroxy-2,3-trans-nonenal to the reduction of β-adrenoceptor function in the heart by oxidative stress

Guido R.M.M. Haenen, Hans J.M. Plug, Nico P.E. Vermeulen, Henk Timmerman, Aalt Bast

Journal:

Year:

1989

Language:

english

File:

PDF, 448 KB

english, 1989

98

Quantification of the Nonenzymatic Fast and Slow TRAP in a Postaddition Assay in Human Seminal Plasma and the Antioxidant Contributions of Various Seminal Compounds

JOHANN P. T. RHEMREV, FLORIS W. P. C. VAN OVERVELD, GUIDO R. M. M. HAENEN, TOM TEERLINK, AALT BAST, Dr. JAN P. W. VERMEIDEN

Journal:

Journal of Andrology

Year:

2000

Language:

english

File:

PDF, 142 KB

english, 2000

99

Role of Cytochrome P450 Polymorphisms in the Development of Pulmonary Drug Toxicity

Petal A. H. M. Wijnen, Professor Marjolein Drent, Patty J. Nelemans, Petra M. J. C. Kuijpers, Ger H. Koek, Cees Neef, Guido R. M. M. Haenen, Otto Bekers

Journal:

Year:

2008

Language:

english

File:

PDF, 119 KB

english, 2008

100

Reduction of the NO-mediated response in the rat aorta by metalloporphyrins

Vreman, Hendrik J, Haenen, Guido R MM, Stevenson, David K, Bast, Aalt

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

2000

Language:

english

File:

PDF, 155 KB

english, 2000