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51

Modulation of μ-mediated antinociception by δ agonists: characterization with antagonists

Julius S. Heyman, Qi Jiang, Richard B. Rothman, Henry I. Mosberg, Frank Porreca

Journal:

European Journal of Pharmacology

Year:

1989

Language:

english

File:

PDF, 623 KB

english, 1989

52

Selective modulation of morphine antinociception, but not development of tolerance, by δ receptor agonists

Jiang Qi, Henry I. Mosberg, Frank Porreca

Journal:

European Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 545 KB

english, 1990

53

Opioid δ receptor subtypes are associated with different potassium channels

Kenneth D. Wild, Todd Vanderah, Henry I. Mosberg, Frank Porreca

Journal:

European Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 150 KB

english, 1991

54

Pharmacological characterization of [D-Ala2,Leu5,Ser6]enkephalin (DALES): antinociceptive actions at the δnon-complexed-opioid receptor

Antonia Mattia, Todd Vanderah, Henry I. Mosberg, John R. Omnaas, Wayne D. Bowen, Frank Porreca

Journal:

European Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 424 KB

english, 1991

55

Mutagenesis and peptide analysis of the DRY motif in the α2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors

Duane A Chung, Susan M Wade, Carol B Fowler, Danielle D Woods, Paolo B Abada, Henry I Mosberg, Richard R Neubig

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 220 KB

english, 2002

56

Differential effects of the novel non-peptidic opioid 4-tyrosylamido-6-benzyl-1,2,3,4 tetrahydroquinoline (CGPM-9) on in vitro rat t lymphocyte and macrophage functions

Mary E. Hicks, Ricardo Gomez-Flores, Chenguang Wang, Henry I. Mosberg, Richard J. Weber

Journal:

Year:

2001

Language:

english

File:

PDF, 141 KB

english, 2001

57

Modulation of Opioid Receptor Ligand Affinity and Efficacy Using Active and Inactive State Receptor Models

Jessica P. Anand, Lauren C. Purington, Irina D. Pogozheva, John R. Traynor, Henry I. Mosberg

Journal:

Chemical Biology & Drug Design

Year:

2012

Language:

english

File:

PDF, 363 KB

english, 2012

58

Estimation of the affinity of naloxone at supraspinal and spinal opioid receptors in vivo: Studies with receptor selective agonists

Julius S. Heyman, Randy J. Koslo, Henry I. Mosberg, Ronald J. Tallarida, Frank Porreca

Journal:

Year:

1986

Language:

english

File:

PDF, 526 KB

english, 1986

59

Cyclic, disulfide- and dithioether-containing opioid tetrapeptides: Development of a ligard with high delta opioid receptor selectivity and affinity

Henry I. Mosberg, John R. Omnaas, Fedor Medzihradsky, Charles B. Smith

Journal:

Year:

1988

Language:

english

File:

PDF, 477 KB

english, 1988

60

Antinociceptive effects of [D-Ala2]deltorphin II, a highly selective δ agonist invivo

Qi Jiang, Henry I. Mosberg, Frank Porreca

Journal:

Year:

1990

Language:

english

File:

PDF, 332 KB

english, 1990

61

Membrane Composition Determines Pardaxin's Mechanism of Lipid Bilayer Disruption

Hallock, Kevin J., Lee, Dong-Kuk, Omnaas, John, Mosberg, Henry I., Ramamoorthy, A.

Journal:

Biophysical Journal

Year:

2002

Language:

english

File:

PDF, 172 KB

english, 2002

62

Conformationally constrained cyclic enkephalin analogs with pronounced delta opioid receptor agonist selectivity

Henry I. Mosberg, Robin Hurst, Victor J. Hruby, James J. Galligan, Thomas F. Burks, Kelvin Gee, Henry I. Yamamura

Journal:

Year:

1983

Language:

english

File:

PDF, 281 KB

english, 1983

63

Cyclic penicillamine containing enkephalin analogs display profound delta receptor selectivities

Henry I. Mosberg, Robin Hurst, Victor J. Hruby, Kelvin Gee, Kazufumi Akiyama, Henry I. Yamamura, James J. Galligan, Thomas F. Burks

Journal:

Year:

1983

Language:

english

File:

PDF, 230 KB

english, 1983

64

A comparison of the analgesic and gastrointestinal transit effects of [D-Pen2, L-Cys5] enkephalin after intracerebroventricular and intrathecal administration to mice

Frank Porreca, Henry I. Mosberg, Robin Hurst, Victor J. Hruby, Thomas F. Burks

Journal:

Year:

1983

Language:

english

File:

PDF, 194 KB

english, 1983

65

Electroencephalographic assessment of the role of δ receptors in opioid peptide - induced seizures

Frank C. Tortella, Lydia Robles, Henry I. Mosberg, John W. Holaday

Journal:

Year:

1984

Language:

english

File:

PDF, 295 KB

english, 1984

66

Studies in vitro with ICI 174, 864, [D-Pen2, D-Pen5]-enkephalin (DPDPE) and [D-Ala2, NMePhe4, Gly-ol]-enkephalin (DAGO)

Lane D. Hirning, Henry I. Mosberg, Robin Hurst, Victor J. Hruby, Thomas F. Burks, Frank Porreca

Journal:

Year:

1985

Language:

english

File:

PDF, 259 KB

english, 1985

67

Homology modeling of opioid receptor-ligand complexes using experimental constraints

Irina D. Pogozheva, Magdalena J. Przydzial, Henry I. Mosberg

Journal:

The AAPS Journal

Year:

2005

Language:

english

File:

PDF, 485 KB

english, 2005

68

Opioid Peptidomimetics: Leads for the Design of Bioavailable Mixed Efficacy μ Opioid Receptor (MOR) Agonist/δ Opioid Receptor (DOR) Antagonist Ligands

Mosberg, Henry I., Yeomans, Larisa, Harland, Aubrie A., Bender, Aaron M., Sobczyk-Kojiro, Katarzyna, Anand, Jessica P., Clark, Mary J., Jutkiewicz, Emily M., Traynor, John R.

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 623 KB

english, 2013

69

Anisotropic Solvent Model of the Lipid Bilayer. 1. Parameterization of Long-Range Electrostatics and First Solvation Shell Effects

Lomize, Andrei L., Pogozheva, Irina D., Mosberg, Henry I.

Journal:

Journal of Chemical Information and Modeling

Year:

2011

Language:

english

File:

PDF, 1.79 MB

english, 2011

70

NMR Structure of the Second Intracellular Loop of the α2A Adrenergic Receptor: Evidence for a Novel Cytoplasmic Helix †,‡

Chung, Duane A., Zuiderweg, Erik R. P., Fowler, Carol B., Soyer, Orkun S., Mosberg, Henry I., Neubig, Richard R.

Journal:

Year:

2002

Language:

english

File:

PDF, 364 KB

english, 2002

71

Structural adaptations of proteins to different biological membranes

Pogozheva, Irina D., Tristram-Nagle, Stephanie, Mosberg, Henry I., Lomize, Andrei L.

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2013

Language:

english

File:

PDF, 4.64 MB

english, 2013

72

Discriminative stimulus effects of a centrally administered, delta-opioid peptide (d-Pen2-d-Pen5-enkephalin) in pigeons

David C. Jewett, Henry I. Mosberg, James H. Woods

Journal:

Psychopharmacology

Year:

1996

Language:

english

File:

PDF, 644 KB

english, 1996

73

Synthesis and evaluation of 4-substituted piperidines and piperazines as balanced affinity μ opioid receptor (MOR) agonist/δ opioid receptor (DOR) antagonist ligands

Bender, Aaron M., Clark, Mary J., Agius, Michael P., Traynor, John R., Mosberg, Henry I.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 484 KB

english, 2014

74

Selectively Promiscuous Opioid Ligands: Discovery of High Affinity/Low Efficacy Opioid Ligands with Substantial Nociceptin Opioid Peptide Receptor Affinity

Kumar, Vinod, Ridzwan, Irna E., Grivas, Konstantinos, Lewis, John W., Clark, Mary J., Meurice, Claire, Jimenez-Gomez, Corina, Pogozheva, Irina, Mosberg, Henry, Traynor, John R., Husbands, Stephen M.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.85 MB

english, 2014

75

PANEL AND CONTRACT PRACTICE

Tortella, Frank C., Echevarria, Eddie, Robles, Lydia, Mosberg, Henry I., Holaday, John W.

Journal:

Year:

1937

Language:

english

File:

PDF, 345 KB

english, 1937

76

Anticonvulsant effects of mu (DAGO) and delta (DPDPE) enkephalins in rats

Tortella, Frank C., Echevarria, Eddie, Robles, Lydia, Mosberg, Henry I., Holaday, John W.

Journal:

Year:

1988

Language:

english

File:

PDF, 538 KB

english, 1988

77

Prediction of Membrane Binding, Orientation and Permeability of Peptide-like Molecules Using a Continuum Model of the Lipid Bilayer

Lomize, Andrei L., Pogozheva, Irina D., Wang, Shaomeng, Mosberg, Henry I.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 94 KB

english, 2009

78

Thermodynamic Approach to Large-Scale Modeling of Alpha-Helices in Membranes

Lomize, Andrei L., Mosberg, Henry I., Pogozheva, Irina D.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 68 KB

english, 2012

79

Large-Scale Computational Analysis of Protein Arrangement in the Lipid Bilayer

Lomize, Andrei L., Pogozheva, Irina, Mosberg, Henry I.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 37 KB

english, 2011

80

Structural Adaptation of Proteins to Different Biological Membranes

Pogozheva, Irina D., Mosberg, Henry I., Lomize, Andrei L.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 38 KB

english, 2013

81

Positioning of Proteins in Membranes of Variable Lipid Composition

Lomize, Andrei L., Lomize, Mikhail A., Pogozheva, Irina D., Mosberg, Henry I.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 62 KB

english, 2010

82

Conformational and dynamic considerations in peptide structure-function studies

Hruby, Victor J., Mosberg, Henry I.

Journal:

Year:

1982

Language:

english

File:

PDF, 810 KB

english, 1982

83

[Part 1: Biological Sciences] || Bis-Penicillamine Enkephalins Possess Highly Improved Specificity toward δ Receptors

Henry I. Mosberg, Robin Hurst, Victor J. Hruby, Kelvin Gee, Henry I. Yamamura, James J. Galligan and Thomas F. Burks

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 859 KB

english, 1983

84

Characterization of [3H][2-D-$\overline{\text{penicillamine},5\text{ -D-p}}\text{enicillamine}$]-enkephalin Binding to δ Opiate Receptors in the Rat Brain and Neuroblastoma--Glioma Hybrid Cell Line (NG 108-15)

Kazufumi Akiyama, Kelvin W. Gee, Henry I. Mosberg, Victor J. Hruby and Henry I. Yamamura

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 1.05 MB

english, 1985

85

Conformational study of the potent peptide hormone antagonist [1-penicillamine,2-leucine]oxytocin in aqueous solution

Mosberg, Henry I., Hruby, Victor J., Meraldi, Jean Paul

Journal:

Year:

1981

Language:

english

File:

PDF, 1.92 MB

english, 1981

86

Development and in Vitro Characterization of a Novel Bifunctional μ-Agonist/δ-Antagonist Opioid Tetrapeptide

Purington, Lauren C., Sobczyk-Kojiro, Katarzyna, Pogozheva, Irina D., Traynor, John R., Mosberg, Henry I.

Journal:

ACS Chemical Biology

Year:

2011

Language:

english

File:

PDF, 2.02 MB

english, 2011

87

Proton nuclear magnetic resonance studies on bacitracin A and its interaction with zinc ion

Mosberg, Henry I., Scogin, Duane A., Storm, Daniel R., Gennis, Robert B.

Journal:

Year:

1980

Language:

english

File:

PDF, 553 KB

english, 1980

88

Substitution on the Phe3 aromatic ring in cyclic .delta. opioid receptor-selective dermorphin/deltorphin tetrapeptide analogs: electronic and lipophilic requirements for receptor affinity

Heyl, Deborah L., Mosberg, Henry I.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.04 MB

english, 1992

89

Incorporation of a novel conformationally restricted tyrosine analog into a cyclic, .delta. opioid receptor selective tetrapeptide (JOM-13) enhances .delta. receptor binding affinity and selectivity

Mosberg, Henry I., Kroona, Heather B.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 330 KB

english, 1992

90

Anisotropic Solvent Model of the Lipid Bilayer. 2. Energetics of Insertion of Small Molecules, Peptides, and Proteins in Membranes

Lomize, Andrei L., Pogozheva, Irina D., Mosberg, Henry I

Journal:

Journal of Chemical Information and Modeling

Year:

2011

Language:

english

File:

PDF, 2.82 MB

english, 2011

91

Peptide and Small Molecules Rescue the Functional Activity and Agonist Potency of Dysfunctional Human Melanocortin-4 Receptor Polymorphisms †,‡

Xiang, Zhimin, Pogozheva, Irina D., Sorenson, Nicholas B., Wilczynski, Andrzej M., Holder, Jerry Ryan, Litherland, Sally A., Millard, William J., Mosberg, Henry I., Haskell-Luevano, Carrie

Journal:

Year:

2007

Language:

english

File:

PDF, 537 KB

english, 2007

92

Combined use of stereospecific deuteration, NMR, distance geometry, and energy minimization for the conformational analysis of the highly .delta. opioid receptor selective peptide [D-Pen2,D-Pen5]enkephalin

Mosberg, Henry I., Sobczyk-Kojiro, Katarzyna, Subramanian, Pullachipatti, Crippen, Gordon M., Ramalingam, Kondareddiar, Woodard, Ronald W.

Journal:

Journal of the American Chemical Society

Year:

1990

Language:

english

File:

PDF, 1.12 MB

english, 1990

93

Development of a Bioavailable μ Opioid Receptor (MOPr) Agonist, δ Opioid Receptor (DOPr) Antagonist Peptide That Evokes Antinociception without Development of Acute Tolerance

Mosberg, Henry I., Yeomans, Larisa, Anand, Jessica P., Porter, Vanessa, Sobczyk-Kojiro, Katarzyna, Traynor, John R., Jutkiewicz, Emily M.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 278 KB

english, 2014

94

Unveiling the Membrane-Binding Properties of N-Terminal and C-Terminal Regions of G Protein-Coupled Receptor Kinase 5 by Combined Optical Spectroscopies

Ding, Bei, Glukhova, Alisa, Sobczyk-Kojiro, Katarzyna, Mosberg, Henry I., Tesmer, John J. G., Chen, Zhan

Journal:

Year:

2014

Language:

english

File:

PDF, 2.93 MB

english, 2014

95

Receptor−Antagonist Interactions in the Complexes of Agouti and Agouti-Related Protein with Human Melanocortin 1 and 4 Receptors †,‡

Chai, Biao-Xin, Pogozheva, Irina D., Lai, Yu-Mei, Li, Ji-Yao, Neubig, Richard R., Mosberg, Henry I., Gantz, Ira

Journal:

Year:

2005

Language:

english

File:

PDF, 561 KB

english, 2005

96

Refinement of a Homology Model of the μ-Opioid Receptor Using Distance Constraints from Intrinsic and Engineered Zinc-Binding Sites †

Fowler, Carol B., Pogozheva, Irina D., LeVine, Harry, Mosberg, Henry I.

Journal:

Year:

2004

Language:

english

File:

PDF, 383 KB

english, 2004

97

Melanocortin Tetrapeptide Ac-His-DPhe-Arg-Trp-NH 2 Modified at the Para Position of the Benzyl Side Chain (DPhe): Importance for Mouse Melanocortin-3 Receptor Agonist versus Antagonist Activity

Proneth, Bettina, Pogozheva, Irina D., Portillo, Federico P., Mosberg, Henry I., Haskell-Luevano, Carrie

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 273 KB

english, 2008

98

Binding of nickel and zinc ions to bacitracin A

Scogin, Duane A., Mosberg, Henry I., Storm, Daniel R., Gennis, Robert B.

Journal:

Year:

1980

Language:

english

File:

PDF, 593 KB

english, 1980

99

Dithioether-containing cyclic peptides

Mosberg, Henry I., Omnaas, John R.

Journal:

Journal of the American Chemical Society

Year:

1985

Language:

english

File:

PDF, 316 KB

english, 1985

100

Interactions of Human Melanocortin 4 Receptor with Nonpeptide and Peptide Agonists †,‡

Pogozheva, Irina D., Chai, Biao-Xin, Lomize, Andrei L., Fong, Tung M., Weinberg, David H., Nargund, Ravi P., Mulholland, Michael W., Gantz, Ira, Mosberg, Henry I.

Journal:

Year:

2005

Language:

english

File:

PDF, 415 KB

english, 2005