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51

Feasibility, safety, and efficacy of the Stretta procedure in Japanese patients with gastroesophageal reflux disease: first report from Asia

Kazuhide Higuchi, Yasuhiro Fujiwara, Hirotoshi Okazaki, Masahiko Tabuchi, Natsuhiko Kameda, Kaori Kadouchi, Hirohisa Machida, Tetsuya Tanigawa, Masatsugu Shiba, Toshio Watanabe, Kazunari Tominaga, Nob

Journal:

Journal of Gastroenterology

Year:

2007

Language:

english

File:

PDF, 276 KB

english, 2007

52

Four-year follow-up of the first case of gastroesophageal reflux disease treated with endoluminal gastroplication in Japan

Kazuhide Higuchi, Masatsugu Shiba, Hirotoshi Okazaki, Masahiko Tabuchi, Natsuhiko Kameda, Kaori Kadouchi, Kazunari Tominaga, Toshio Watanabe, Yasuhiro Fujiwara, Nobuhide Oshitani, Tetsuo Arakawa

Journal:

Journal of Gastroenterology

Year:

2007

Language:

english

File:

PDF, 166 KB

english, 2007

53

Synergistic antitumor effect of combined 5-fluorouracil (5-FU) with 5-chloro-2,4-dihydroxypyridine on 5-FU-resistant gastric cancer cells: possible role of a dihydropyrimidine dehydrogenase-independent mechanism

Eiji Sasaki, Kazunari Tominaga, Hikaru Kuwamura, Toshio Watanabe, Yasuhiro Fujiwara, Nobuhide Oshitani, Kazuhide Higuchi, Tetsuo Arakawa

Journal:

Journal of Gastroenterology

Year:

2007

Language:

english

File:

PDF, 206 KB

english, 2007

54

A prospective, single-blind trial comparing wireless capsule endoscopy and double-balloon enteroscopy in patients with obscure gastrointestinal bleeding

Natsuhiko Kameda, Kazuhide Higuchi, Masatsugu Shiba, Hirohisa Machida, Hirotoshi Okazaki, Hirokazu Yamagami, Tetsuya Tanigawa, Kenji Watanabe, Toshio Watanabe, Kazunari Tominaga, Yasuhiro Fujiwara, No

Journal:

Journal of Gastroenterology

Year:

2008

Language:

english

File:

PDF, 280 KB

english, 2008

55

Perfectionism underlying psychological background correlated with the symptoms of functional dyspepsia

Masahiro Ochi, Kazunari Tominaga, Toshiya Iketani, Kaori Kadouchi, Tetsuya Tanigawa, Masatsugu Shiba, Toshio Watanabe, Yasuhiro Fujiwara, Nobuhide Oshitani, Kazuhide Higuchi, Nobuo Kiriike, Tetsuo Ara

Journal:

Journal of Gastroenterology

Year:

2008

Language:

english

File:

PDF, 176 KB

english, 2008

56

Long-term use of nonsteroidal anti-inflammatory drugs normalizes the kinetics of gastric epithelial cells in patients withHelicobacter pyloriinfection via attenuation of gastric mucosal inflammation

Tetsuya Tanigawa, Toshio Watanabe, Kazuhide Higuchi, Kazunari Tominaga, Yasuhiro Fujiwara, Nobuhide Oshitani, Andrzej S. Tarnawski, Tetsuo Arakawa

Journal:

Journal of Gastroenterology

Year:

2009

Language:

english

File:

PDF, 422 KB

english, 2009

57

Present status and strategy of NSAIDs-induced small bowel injury

Kazuhide Higuchi, Eiji Umegaki, Toshio Watanabe, Yukiko Yoda, Eijiro Morita, Mitsuyuki Murano, Satoshi Tokioka, Tetsuo Arakawa

Journal:

Journal of Gastroenterology

Year:

2009

Language:

english

File:

PDF, 437 KB

english, 2009

58

Steroid complications and surgery in intractable ulcerative colitis

Masaru Shinozaki, Kimitaka Suzuki, Toshio Sawada, Nelson Tsuno, Yoshiki Higuchi, Tetsuichiro Muto

Journal:

Journal of Gastroenterology

Year:

1998

Language:

english

File:

PDF, 116 KB

english, 1998

59

Evaluation of serum fetuin-A relationships with biochemical parameters in patients on hemodialysis

Osamu Oikawa, Terumi Higuchi, Toshio Yamazaki, Chii Yamamoto, Noboru Fukuda, Koichi Matsumoto

Journal:

Clinical and Experimental Nephrology

Year:

2007

Language:

english

File:

PDF, 260 KB

english, 2007

60

Rebamipide Reduces Delay in Gastric Ulcer Healing in Cyclooxygenase-2-Deficient Mice

Toshio Watanabe, Kazuhide Higuchi, Koichi Taira, Eiji Sasaki, Masatsugu Shiba, Kazunari Tominaga, Yasuhiro Fujiwara, Nobuhide Oshitani, Tetsuo Arakawa

Journal:

Digestive Diseases and Sciences

Year:

2005

Language:

english

File:

PDF, 107 KB

english, 2005

61

15th Anniversary of Rebamipide: Looking Ahead to the New Mechanisms and New Applications

Tetsuo Arakawa, Kazuhide Higuchi, Yasuhiro Fujiwara, Toshio Watanabe, Kazunari Tominaga, Eiji Sasaki, Nobuhide Oshitani, Toshikazu Yoshikawa, Andrzej S. Tarnawski

Journal:

Digestive Diseases and Sciences

Year:

2005

Language:

english

File:

PDF, 480 KB

english, 2005

62

Anti-Inflammatory Effects of Pravastatin onHelicobacter Pylori-Induced Gastritis in Mice

Masanori Yamato, Toshio Watanabe, Kazuhide Higuchi, Koichi Taira, Tetsuya Tanigawa, Masatsugu Shiba, Kazunari Tominaga, Yasuhiro Fujiwara, Nobuhide Oshitani, Koji Takeuchi, Tetsuo Arakawa

Journal:

Digestive Diseases and Sciences

Year:

2007

Language:

english

File:

PDF, 404 KB

english, 2007

63

Neoadjuvant endocrine therapy of breast cancer: which patients would benefit and what are the advantages?

Hiroyuki Takei, Masafumi Kurosumi, Takashi Yoshida, Yuji Hayashi, Toru Higuchi, Sayaka Uchida, Jun Ninomiya, Hanako Oba, Kenichi Inoue, Shigenori Nagai, Toshio Tabei

Journal:

Year:

2011

Language:

english

File:

PDF, 188 KB

english, 2011

64

Triterpenoid sapogenins from leaves of Pittosporum undulatum

Ryuichi Higuchi, Tetsuya Komori, Toshio Kawasaki, Erich V. Lassak

Journal:

Year:

1983

Language:

english

File:

PDF, 288 KB

english, 1983

65

Observations of energy metabolism in neuroectodermal tumors using in vivo 31P-NMR

Shoji Naruse, Yoshiharu Horikawa, Chuzo Tanaka, Toshio Higuchi, Satoshi Ueda, Kimiyoshi Hirakawa, Hiroyasu Nishikawa, Hiroshi Watari

Journal:

Magnetic Resonance Imaging

Year:

1985

Language:

english

File:

PDF, 636 KB

english, 1985

66

Syntheses and preventive effects of analogues related to 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71) on bone mineral loss in ovariectomized rats

Yoshiyuki Ono, Akira Kawase, Hiroyoshi Watanabe, Ayako Shiraishi, Satoshi Takeda, Yoshinobu Higuchi, Katsuhiko Sato, Tsuyoshi Yamauchi, Tetsuhiro Mikami, Masahiro Kato, Naoko Tsugawa, Toshio Okano, No

Journal:

Bioorganic & Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 733 KB

english, 1998

67

Increased expression of transforming growth factor-alpha and epidermal growth factor receptors in rat chronic reflux esophagitis

YASUHIRO FUJIWARA, KAZUHIDE HIGUCHI, MASAKI HAMAGUCHI, TAKASHI TAKASHIMA, TOSHIO WATANABE, KAZUNARI TOMINAGA, NOBUHIDE OSHITANI, TAKAYUKI MATSUMOTO, TETSUO ARAKAWA

Journal:

Journal of Gastroenterology and Hepatology

Year:

2004

Language:

english

File:

PDF, 284 KB

english, 2004

68

Prevalence of gastroesophageal reflux disease and gastroesophageal reflux disease symptoms in Japan

YASUHIRO FUJIWARA, KAZUHIDE HIGUCHI, YOKO WATANABE, MASATSUGU SHIBA, TOSHIO WATANABE, KAZUNARI TOMINAGA, NOBUHIDE OSHITANI, TAKAYUKI MATSUMOTO, HIDEKI NISHIKAWA, TETSUO ARAKAWA

Journal:

Journal of Gastroenterology and Hepatology

Year:

2005

Language:

english

File:

PDF, 73 KB

english, 2005

69

Plummer–Vinson syndrome successfully treated by endoscopic dilatation

Masaru Enomoto, Madoka Kohmoto, Usama Ahmed Arafa, Masatsugu Shiba, Toshio Watanabe, Kazunari Tominaga, Yasuhiro Fujiwara, Yoshihiko Saeki, Kazuhide Higuchi, Shuhei Nishiguchi, Susumu Shiomi, Haruji O

Journal:

Journal of Gastroenterology and Hepatology

Year:

2007

Language:

english

File:

PDF, 180 KB

english, 2007

70

What are the risk factors for aggravation of esophageal varices in patients with hepatocellular carcinoma?

Kaori Kadouchi, Kazuhide Higuchi, Masatsugu Shiba, Hirotoshi Okazaki, Kazuki Yamamori, Eiji Sasaki, Kazunari Tominaga, Toshio Watanabe, Yasuhiro Fujiwara, Nobuhide Oshitani, Tetsuo Arakawa

Journal:

Journal of Gastroenterology and Hepatology

Year:

2007

Language:

english

File:

PDF, 115 KB

english, 2007

71

Transient immunoglobulin-complexed aspartate aminotransferase in infancy caused by maternal immunoglobulin G

Hajime Yasuhara, Takanori Moriyama, Banryoku Higuchi, Masayuki Nishiguchi, Atsuko Nakanou, Tetsuya Sakaue, Hiroyuki Morimoto, Yoshitsugu Sakagami, Yoshikatsu Sawamoto, Toshio Takase

Journal:

Pediatrics International

Year:

2010

Language:

english

File:

PDF, 479 KB

english, 2010

72

The Influence of Uremic Serum on Interleukin-1β and Interleukin-1 Receptor Antagonist Production by Peripheral Blood Mononuclear Cells

Terumi Higuchi, Noboru Fukuda, Chii Yamamoto, Toshio Yamazaki, Osamu Oikawa, Yoshihiko Ohnishi, Kazuyoshi Okada, Masayoshi Soma, Koichi Matsumoto

Journal:

Therapeutic Apheresis and Dialysis

Year:

2006

Language:

english

File:

PDF, 148 KB

english, 2006

73

A Case Report of Hemodialysis Intolerance With Eosinophilia

Terumi Higuchi, Toshio Yamazaki, Yoshihiko Ohnishi, Shiro Matsumoto, Minako Yabuki, Syoko Kitajima, Yoshinori Toshida, Noriaki Maruyama, Osamu Oikawa, Kazuyoshi Okada, Noboru Fukuda, Masayoshi Soma, K

Journal:

Therapeutic Apheresis and Dialysis

Year:

2007

Language:

english

File:

PDF, 95 KB

english, 2007

74

10.1038/31520

Shingyoji, Chikako, Higuchi, Hideo, Yoshimura, Misako, Katayama, Eisaku, Yanagida, Toshio

Journal:

Year:

1998

Language:

english

File:

PDF, 339 KB

english, 1998

75

10.1038/31525

Shingyoji, Chikako, Higuchi, Hideo, Yoshimura, Misako, Katayama, Eisaku, Yanagida, Toshio

Journal:

Year:

1998

Language:

english

File:

PDF, 265 KB

english, 1998

76

10.1038/31527

Shingyoji, Chikako, Higuchi, Hideo, Yoshimura, Misako, Katayama, Eisaku, Yanagida, Toshio

Journal:

Year:

1998

Language:

english

File:

PDF, 89 KB

english, 1998

77

Substeps within the 8-nm step of the ATPase cycle of single kinesin molecules

Nishiyama, Masayoshi, Muto, Etsuko, Inoue, Yuichi, Yanagida, Toshio, Higuchi, Hideo

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 1.07 MB

english, 2001

78

The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module

Terawaki, Shin-ichi, Kitano, Ken, Mori, Tomoyuki, Zhai, Yan, Higuchi, Yoshiki, Itoh, Norimichi, Watanabe, Takashi, Kaibuchi, Kozo, Hakoshima, Toshio

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 2.89 MB

english, 2009

79

Chemomechanical coupling of the forward and backward steps of single kinesin molecules

Nishiyama, Masayoshi, Higuchi, Hideo, Yanagida, Toshio

Journal:

Nature Cell Biology

Year:

2002

Language:

english

File:

PDF, 301 KB

english, 2002

80

Alfacalcidol Inhibits Bone Resorption and Stimulates Formation in an Ovariectomized Rat Model of Osteoporosis: Distinct Actions from Estrogen

Ayako Shiraishi, Satoshi Takeda, Toshimi Masaki, Yoshinobu Higuchi, Yasushi Uchiyama, Noboru Kubodera, Katsuhiko Sato, Kyoji Ikeda, Toshitaka Nakamura, Toshio Matsumoto, Etsuro Ogata

Journal:

Journal of Bone and Mineral Research

Year:

2000

Language:

english

File:

PDF, 299 KB

english, 2000

81

Expression of Gene for EIIIA- and EIIIB- Fibronectin, Fetal Types of Fibronectin, During Gastric Ulcer Healing in Rats

Kazunari Tominaga, Kazuhide Higuchi, Toshio Watanabe, Yasuhiro Fujiwara, Shokei Kim, Tetsuo Arakawa, Hiroshi Iwao, Tetsuo Kuroki

Journal:

Digestive Diseases and Sciences

Year:

2001

Language:

english

File:

PDF, 1.34 MB

english, 2001

82

Neutrophil Accumulation in Development of Gastric Ulcer Induced by Submucosal Injection of Endothelin-1 in Rats

Toshio Watanabe, Tetsuo Arakawa, Kazunari Tominaga, Yasuhiro Fujiwara, Kazuhide Higuchi, Tetsuo Kuroki

Journal:

Digestive Diseases and Sciences

Year:

2000

Language:

english

File:

PDF, 1.92 MB

english, 2000

83

Mechanisms and Roles of Neutrophil Infiltration in Stress-Induced Gastric Injury in Rats

Masaki Hamaguchi, Toshio Watanabe, Kazuhide Higuchi, Kazunari Tominaga, Yasuhiro Fujiwara, Tetsuo Arakawa

Journal:

Digestive Diseases and Sciences

Year:

2001

Language:

english

File:

PDF, 1.19 MB

english, 2001

84

Rebamipide Prevents Delay of Acetic Acid-Induced Gastric Ulcer Healing Caused byHelicobacter pyloriInfection in Mongolian Gerbils

Toshio Watanabe, Kazuhide Higuchi, Masaki Hamaguchi, Tetsuya Tanigawa, Rikimon Wada, Kazunari Tominaga, Yasuhiro Fujiwara, Tetsuo Arakawa

Journal:

Digestive Diseases and Sciences

Year:

2002

Language:

english

File:

PDF, 87 KB

english, 2002

85

No Additive Effect BetweenHelicobacter pyloriInfection and Portal Hypertensive Gastropathy on Inducible Nitric Oxide Synthase Expression in Gastric Mucosa of Cirrhotic Patients

Usama A. Arafa, Yasuhiro Fujiwara, Kazuhide Higuchi, Masatsugu Shiba, Toshiyuki Uchida, Toshio Watanabe, Kazunari Tominaga, Nobuhide Oshitani, Takayuki Matsumoto, Tetsuo Arakawa

Journal:

Digestive Diseases and Sciences

Year:

2003

Language:

english

File:

PDF, 100 KB

english, 2003

86

Production of Reactive Oxygen Species in Peripheral Blood is Increased in Individuals with Helicobacter pylori Infection and Decreased after its Eradication

Masayuki Mashimo, Manabu Nishikawa, Kazuhide Higuchi, Masaki Hirose, Qian Wei, Anwarul Haque, Eiji Sasaki, Masatsugu Shiba, Kazunari Tominaga, Toshio Watanabe, Yasuhiro Fujiwara, Tetsuo Arakawa, Masay

Journal:

Year:

2006

Language:

english

File:

PDF, 179 KB

english, 2006

87

HTLV-I proviral load correlates with progression of motor disability in HAM/TSP: Analysis of 239 HAM/TSP patients including 64 patients followed up for 10 years

Toshio Matsuzaki, Masanori Nakagawa, Masahiro Nagai, Koichiro Usuku, Itsuro Higuchi, Kimiyoshi Arimura, Hiroaki Kubota, Shuji Izumo, Suminori Akiba, Mitsuhiro Osame

Journal:

Journal of NeuroVirology

Year:

2001

Language:

english

File:

PDF, 535 KB

english, 2001

88

Mechanisms of peptic ulcer recurrence: role of inflammation

Toshio Watanabe, Kazuhide Higuchi, Tetsuya Tanigawa, Kazunari Tominaga, Yasuhiro Fujiwara, Tetsuo Arakawa

Journal:

Inflammopharmacology

Year:

2002

Language:

english

File:

PDF, 462 KB

english, 2002

89

Functional oesophageal epithelial defense against acid

Yasuhiro Fujiwara, Kazuhide Higuchi, Kazunari Tominaga, Toshio Watanabe, Nobuhide Oshitani, Tetsuo Arakawa

Journal:

Inflammopharmacology

Year:

2005

Language:

english

File:

PDF, 611 KB

english, 2005

90

AP-1 and colorectal cancer

Reiko Ashida, Kazunari Tominaga, Eiji Sasaki, Toshio Watanabe, Yasuhiro Fujiwara, Nobuhide Oshitani, Kazuhide Higuchi, Shokei Mitsuyama, Hiroshi Iwao, Tetsuo Arakawa

Journal:

Inflammopharmacology

Year:

2005

Language:

english

File:

PDF, 484 KB

english, 2005

91

Merged bipolar transistor models including the substrate current

Susumu Inohira, Toshio Shinmi, Hisayuki Higuchi, Kyoichi Iida, Hiroshi Ohkawara

Journal:

Electronics and Communications in Japan (Part II: Electronics))

Year:

1990

Language:

english

File:

PDF, 659 KB

english, 1990

92

Overexpression of p53 protein and histologic grades of dysplasia in colorectal adenomas

Shinichi Sameshima, Yoshiro Kubota, Toshio Sawada, Toshiaki Watanabe, Toshihiko Kuroda, Nelson Tsuno, Yoshiki Higuchi, Masaru Shinozaki, Koki Sunouchi, Tadahiko Masaki, Yukio Saito, Tetsuichiro Muto

Journal:

Diseases of the Colon & Rectum

Year:

1996

Language:

english

File:

PDF, 1.02 MB

english, 1996

93

Zinc deficiency delays gastric ulcer healing in rats

Toshio Watanabe, Tetsuo Arakawa, Takashi Fukuda, Kazuhide Higuchi, Kenzo Kobayashi

Journal:

Digestive Diseases and Sciences

Year:

1995

Language:

english

File:

PDF, 485 KB

english, 1995

94

Indomethacin treatment during initial period of acetic acid-induced rat gastric ulcer healing promotes persistent polymorphonuclear cell-infiltration and increases future ulcer recurrence

Tetsuo Arakawa, Toshio Watanabe, Takashi Fukuda, Kazuhide Higuchi, Osamu Takaishi, Katsuya Yamasaki, Kenzo Kobayashi, Andrzej Tarnawski

Journal:

Digestive Diseases and Sciences

Year:

1996

Language:

english

File:

PDF, 731 KB

english, 1996

95

Reduced coenzyme Q10 supplementation decelerates senescence in SAMP1 mice

Jingmin Yan, Kenji Fujii, Junjie Yao, Hideyuki Kishida, Kazunori Hosoe, Jinko Sawashita, Toshio Takeda, Masayuki Mori, Keiichi Higuchi

Journal:

Experimental Gerontology

Year:

2006

Language:

english

File:

PDF, 187 KB

english, 2006

96

Genetic and enzymatic analyses of metalloprotease (aureolysin) from Staphylococcus aureus isolated from domestic animals

Shotaro Takeuchi, Minoru Saito, Keisuke Imaizumi, Toshio Kaidoh, Hiroki Higuchi, Sachiko Inubushi

Journal:

Veterinary Microbiology

Year:

2002

Language:

english

File:

PDF, 221 KB

english, 2002

97

Structural gene and strain specificity of a novel cysteine protease produced by Staphylococcus aureus isolated from a diseased chicken

Shotaro Takeuchi, Kazue Matsunaga, Sachiko Inubushi, Hiroki Higuchi, Keisuke Imaizumi, Toshio Kaidoh

Journal:

Veterinary Microbiology

Year:

2002

Language:

english

File:

PDF, 327 KB

english, 2002

98

Effect of amino acid substitutions in the epitope regions of pyolysin from Arcanobacterium pyogenes

Keisuke Imaizumi, Kazue Matsunaga, Hiroki Higuchi, Toshio Kaidoh, Shotaro Takeuchi

Journal:

Veterinary Microbiology

Year:

2003

Language:

english

File:

PDF, 197 KB

english, 2003

99

Management and design of the maintenance of sam mouse strains: an animal model for accelerated senescence and age-associated disorders

Masanori Hosokawa, Toshio Abe, Keiichi Higuchi, Kozo Shimakawa, Yoshiaki Omori, Takatoshi Matsushita, Kumiko Kogishi, Eishi Deguchi, Yoshiko Kishimoto, Kuraichi Yasuoka, Toshio Takeda

Journal:

Experimental Gerontology

Year:

1997

Language:

english

File:

PDF, 355 KB

english, 1997

100

Pathobiology of the senescence-accelerated mouse (SAM)

Toshio Takeda, Takatoshi Matsushita, Mafumi Kurozumi, Kiminobu Takemura, Keiichi Higuchi, Masanori Hosokawa

Journal:

Experimental Gerontology

Year:

1997

Language:

english

File:

PDF, 716 KB

english, 1997