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1

Incidence of Adult Respiratory Distress Syndrome (ARDS) in trauma patients

Pfeifer, Roman, Heussen, Nicole, Michalewicz, Emilia, Hilgers, Ralf-Dieter, Pape, Hans-Christoph

Journal:

Journal of Trauma and Acute Care Surgery

Year:

2017

Language:

english

File:

PDF, 3.27 MB

english, 2017

2

Recommendations for the design of small population clinical trials

Day, Simon, Jonker, Anneliene Hechtelt, Lau, Lilian Pek Lian, Hilgers, Ralf-Dieter, Irony, Ilan, Larsson, Kristina, Roes, Kit CB, Stallard, Nigel

Journal:

Orphanet Journal of Rare Diseases

Year:

2018

Language:

english

File:

PDF, 623 KB

english, 2018

3

D-optimal design for Becker's minimum polynomial

Ralf-Dieter Hilgers

Journal:

Statistics & Probability Letters

Year:

2000

Language:

english

File:

PDF, 81 KB

english, 2000

4

Aluminosis – Detection of an almost forgotten disease with HRCT

Thomas Kraus, Karl Heinz Schaller, Jürgen Angerer, Ralf-Dieter Hilgers, Stephan Letzel

Journal:

Journal of Occupational Medicine and Toxicology

Year:

2006

Language:

english

File:

PDF, 1013 KB

english, 2006

5

Scleral Buckling versus Primary Vitrectomy in Rhegmatogenous Retinal Detachment: A Prospective Randomized Multicenter Clinical Study

Heinrich Heimann, Karl Ulrich Bartz-Schmidt, Norbert Bornfeld, Claudia Weiss, Ralf-Dieter Hilgers, Michael H. Foerster

Journal:

Year:

2007

Language:

english

File:

PDF, 828 KB

english, 2007

6

Consideration of effect of the amount of mandibular setback on the submental region in the planning of orthodontic–orthognathic treatment

Ghassemi, Mehrangiz, Hilgers, Ralf-Dieter, Jamilian, Abdolreza, Hölzle, Frank, Fritz, Ulrike, Gerressen, Marcus, Ghassemi, Alireza

Journal:

British Journal of Oral and Maxillofacial Surgery

Year:

2014

Language:

english

File:

PDF, 760 KB

english, 2014

7

Effect of maxillary advancement on the change in the soft tissues after treatment of patients with class III malocclusion

Ghassemi, Mehrangiz, Hilgers, Ralf-Dieter, Jamilian, Abdolreza, Shokatbakhsh, Abdolrahman, Hölzle, Frank, Fritz, Ulrike, Ghassemi, Alireza

Journal:

British Journal of Oral and Maxillofacial Surgery

Year:

2015

Language:

english

File:

PDF, 987 KB

english, 2015

8

Combined Tin-Containing Fluoride Solution and CO2 Laser Treatment Reduces Enamel Erosion in vitro

Esteves-Oliveira, Marcella, Witulski, Nadine, Hilgers, Ralf-Dieter, Apel, Christian, Meyer-Lueckel, Hendrik, de Paula Eduardo, Carlos

Journal:

Caries Research

Year:

2015

Language:

english

File:

PDF, 907 KB

english, 2015

9

Estimating the reliability of repeatedly measured endpoints based on linear mixed-effects models. A tutorial

Van der Elst, Wim, Molenberghs, Geert, Hilgers, Ralf-Dieter, Verbeke, Geert, Heussen, Nicole

Journal:

Pharmaceutical Statistics

Year:

2016

Language:

english

File:

PDF, 567 KB

english, 2016

10

Directions for new developments on statistical design and analysis of small population group trials

Hilgers, Ralf-Dieter, Roes, Kit, Stallard, Nigel

Journal:

Orphanet Journal of Rare Diseases

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

11

Lessons learned from IDeAl — 33 recommendations from the IDeAl-net about design and analysis of small population clinical trials

Hilgers, Ralf-Dieter, Bogdan, Malgorzata, Burman, Carl-Fredrik, Dette, Holger, Karlsson, Mats, König, Franz, Male, Christoph, Mentré, France, Molenberghs, Geert, Senn, Stephen

Journal:

Orphanet Journal of Rare Diseases

Year:

2018

Language:

english

File:

PDF, 1.00 MB

english, 2018

12

Observations below multiple lower limits of quantification: How to estimate the mean and variance

Berger, Tanja, Hilgers, Ralf-Dieter, Heussen, Nicole

Journal:

Biometrical Journal

Year:

2018

Language:

english

File:

PDF, 1.76 MB

english, 2018

13

Design and analysis of stratified clinical trials in the presence of bias

Hilgers, Ralf-Dieter, Manolov, Martin, Heussen, Nicole, Rosenberger, William F

Journal:

Statistical Methods in Medical Research

Year:

2019

Language:

english

File:

PDF, 408 KB

english, 2019

14

Design Efficiency and Estimation for Component Amount Models

Ralf-Dieter Hilgers

Journal:

Biometrical Journal

Year:

1999

Language:

english

File:

PDF, 260 KB

english, 1999

15

Optimal designs for mixture amount experiments

Ralf-Dieter Hilgers, Peter Bauer

Journal:

Journal of Statistical Planning and Inference

Year:

1995

Language:

english

File:

PDF, 305 KB

english, 1995

16

The impact of selection bias on test decisions in randomized clinical trials

Lieven Nils Kennes, Erhard Cramer, Ralf-Dieter Hilgers, Nicole Heussen

Journal:

Statistics in Medicine

Year:

2011

Language:

english

File:

PDF, 140 KB

english, 2011

17

The normalised rim/disc area ratio line

Karl Ulrich Bartz-Schmidt, Christian Paul Jonescu-Cuypers, Gabriele Thumann, Juliane Frucht, Andrea Sengersdorf, Ralf-Dieter Hilgers, Günter Karl Krieglstein

Journal:

International Ophthalmology

Year:

1995-1996

Language:

english

File:

PDF, 1.18 MB

english, 1995-1996

18

The cumulative normalised rim/disc area ratio curve

Karl Ulrich Bartz-Schmidt, Andrea Sengersdorf, Peter Esser, Peter Walter, Ralf-Dieter Hilgers, Günter Karl Krieglstein

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

1996

Language:

english

File:

PDF, 1.10 MB

english, 1996

19

Effect of the Sequence of Lateral Osteotomy and Hump Removal on the Aesthetic Outcome

Alireza Ghassemi, Andreas Prescher, Ralf-Dieter Hilgers, Dieter Riediger, Marcus Gerressen

Journal:

Aesthetic Plastic Surgery

Year:

2011

Language:

english

File:

PDF, 241 KB

english, 2011

20

Triamcinolone versus inner-limiting membrane peeling in persistent diabetic macular edema (TIME study): design issues and implications

Antonia M. Joussen, Claudia Weiss, Diana Bauer, Ralf-Dieter Hilgers, on behalf of the TIME Study group

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2007

Language:

english

File:

PDF, 136 KB

english, 2007

21

Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR Study): predictive factors for functional outcome. Study report no. 6

Nicole Heussen, Nicolas Feltgen, Peter Walter, Hans Hoerauf, Ralf-Dieter Hilgers, Heinrich Heimann, The SPR Study Group

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2011

Language:

english

File:

PDF, 150 KB

english, 2011

22

Long-term fluctuations of the normalised rim/disc area ratio quotient in normal eyes

Christian Paul Jonescu-Cuypers, Gabriele Thumann, Ralf-Dieter Hilgers, Karl Ulrich Bartz-Schmidt, Ralf Krott, Günter Karl Krieglstein

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

1999

Language:

english

File:

PDF, 81 KB

english, 1999

23

In vitro adherence and accumulation ofStaphylococcus epidermidisRP 62 A andStaphylococcus epidermidisM7 on four different bone cements

Dietmar König, Jörg Schierholz, Ralf-Dieter Hilgers, Christoph Bertram, Francoise Perdreau-Remington, Jürgen Rütt

Journal:

Langenbeck's Archives of Surgery

Year:

2001

Language:

english

File:

PDF, 69 KB

english, 2001

24

Laser-assisted in-office bleaching using a neodymium:yttrium–aluminum–garnet laser: an in vivo study

Andrea Strobl, Norbert Gutknecht, René Franzen, Ralf-Dieter Hilgers, Friedrich Lampert, Jörg Meister

Journal:

Lasers in Medical Science

Year:

2010

Language:

english

File:

PDF, 271 KB

english, 2010

25

Heavy silicone oil versus standard silicone oil as vitreous tamponade in inferior PVR (HSO Study): design issues and implications

Antonia M. Joussen, Bernd Kirchhof, Norbert Schrage, Christina Ocklenburg, Ralf-Dieter Hilgers, on behalf of the HSO Study Group

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2007

Language:

english

File:

PDF, 584 KB

english, 2007

26

Purely cancellous vs. corticocancellous bone in sinus floor augmentation with autogenous iliac crest: a prospective clinical trial

Marcus Gerressen, Benita Hermanns-Sachweh, Dieter Riediger, Ralf-Dieter Hilgers, Hubertus Spiekermann, Alireza Ghassemi

Journal:

Clinical Oral Implants Research

Year:

2009

Language:

english

File:

PDF, 813 KB

english, 2009

27

An immunochemical quantitative analysis of the protein pattern in physiologic and pathologic vitreous

Ralf Clausen, Michael Weller, Peter Wiedemann, Klaus Heimann, Ralf-Dieter Hilgers, Karl Zilles

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

1991

Language:

english

File:

PDF, 618 KB

english, 1991

28

Daunomycin and silicone oil for the treatment of proliferative vitreoretinopathy

Peter Wiedemann, Claudia Leinung, Ralf-Dieter Hilgers, Klaus Heimann

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

1991

Language:

english

File:

PDF, 290 KB

english, 1991

29

Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment (SPR Study): Design issues and implications

Heinrich Heimann, Martin Hellmich, Norbert Bornfeld, Karl-Ulrich Bartz-Schmidt, Ralf-Dieter Hilgers, Michael H. Foerster

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2001

Language:

english

File:

PDF, 178 KB

english, 2001

30

Comparison of Donor-Site Engraftment After Harvesting Vascularized and Nonvascularized Iliac Bone Grafts

Alireza Ghassemi, Mehrangiz Ghassemi, Dieter Riediger, Ralf-Dieter Hilgers, Marcus Gerressen

Journal:

Journal of Oral and Maxillofacial Surgery

Year:

2009

Language:

english

File:

PDF, 634 KB

english, 2009

31

Effect of tooth preparation design on bond strengths of resin-bonded prostheses: A pilot study

Mahmoud A. El Salam Shakal, Peter Pfeiffer, Ralf-Dieter Hilgers

Journal:

The Journal of Prosthetic Dentistry

Year:

1997

Language:

english

File:

PDF, 4.30 MB

english, 1997

32

Sleep apnoea in treated acromegaly: relative frequency and predisposing factors

Felix Rosenow, Stefan Reuter, Ulrich Deuß, Brigitte Szelies, Ralf-Dieter Hilgers, Werner Winkelmann, Wolf-Dieter Heiss

Journal:

Clinical Endocrinology

Year:

1996

Language:

english

File:

PDF, 170 KB

english, 1996

33

The effect of water storage and light exposure on the color and translucency of a hybrid and a microfilled composite

Wolfgang Buchalla, Thomas Attin, Ralf-Dieter Hilgers, Elmar Hellwig

Journal:

The Journal of Prosthetic Dentistry

Year:

2002

Language:

english

File:

PDF, 99 KB

english, 2002

34

Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR study): Risk assessment of anatomical outcome. SPR study report no. 7

Nicolas Feltgen, Heinrich Heimann, Hans Hoerauf, Peter Walter, Ralf-Dieter Hilgers, Nicole Heussen, On behalf of Writing group for the SPR study investigators*

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2012

Language:

english

File:

PDF, 196 KB

english, 2012

35

Selective Left Ventricular Adriamycin-Induced Cardiomyopathy in the Pig

Stefan Christiansen, Alberto Perez-Bouza, Gereon Schälte, Ralf-Dieter Hilgers, Rüdiger Autschbach

Journal:

The Journal of Heart and Lung Transplantation

Year:

2008

Language:

english

File:

PDF, 566 KB

english, 2008

36

Author reply

Heinrich Heimann, Karl-Ulrich Bartz-Schmidt, Norbert Bornfeld, Claudia Weiss, Ralf-Dieter Hilgers, Michael H. Foerster

Journal:

Year:

2008

Language:

english

File:

PDF, 51 KB

english, 2008

37

Is Significant Relevant? Validity and Patient Benefit of Randomized Controlled Clinical Trials on Age-related Macular Degeneration

Antonia M. Joussen, Walter Lehmacher, Ralf-Dieter Hilgers, Bernd Kirchhof

Journal:

Survey of Ophthalmology

Year:

2007

Language:

english

File:

PDF, 194 KB

english, 2007

38

Transplantation of autologous retinal pigment epithelium in eyes with foveal neovascularization resulting from age-related macular degeneration: a pilot study

Susanne Binder, Ulrike Stolba, Ilse Krebs, Lukas Kellner, Christian Jahn, Hans Feichtinger, Margit Povelka, Ursula Frohner, Andreas Kruger, Ralf-Dieter Hilgers, Walter Krugluger

Journal:

American Journal of Ophthalmology

Year:

2002

Language:

english

File:

PDF, 513 KB

english, 2002

39

Author reply

Susanne Binder, Ulrike Stolba, Ilse Krebs, Lukas Kellner, Christian Jahn, Hans Feichtinger, Margit Pavelka, Ursula Frohner, Andreas Kruger, Ralf-Dieter Hilgers, Walter Krughuger

Journal:

American Journal of Ophthalmology

Year:

2002

Language:

english

File:

PDF, 55 KB

english, 2002

40

Author reply

Susanne Binder, Ulrike Stolba, Ilse Krebs, Lukas Kellner, Christian Jahn, Hans Feichtinger, Margit Pavelka, Ursula Frohner, Andreas Kruger, Ralf-Dieter Hilgers, Walter Krugluger

Journal:

American Journal of Ophthalmology

Year:

2002

Language:

english

File:

PDF, 48 KB

english, 2002

41

Adherence to and accumulation of S. epidermidis on different biomaterials due to extracellular slime production: In vitro comparison of a slime-producing strain (Rp 62 A) and its isogenic slime negative mutant (M7)

Dietmar Pierre König, Francoise Perdreau-Remington, Jürgen Rütt, Ralf-Dieter Hilgers, Jörg Michael Schierholz

Journal:

Zentralblatt für Bakteriologie

Year:

1999

Language:

english

File:

PDF, 1.58 MB

english, 1999

42

Implant placement under existing removable dental prostheses and its effect on oral health-related quality of life

Stefan Wolfart, Daniel Moll, Ralf-Dieter Hilgers, Mona Wolfart, Matthias Kern

Journal:

Clinical Oral Implants Research

Year:

2012

Language:

english

File:

PDF, 154 KB

english, 2012

43

Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR Study): Multiple-event analysis of risk factors for reoperations. SPR Study report no. 4

Nicole Heussen, Ralf-Dieter Hilgers, Heinrich Heimann, Lawrence Collins, Salvatore Grisanti, for the SPR study group

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2011

Language:

english

File:

PDF, 191 KB

english, 2011

44

Heavy silicone oil versus standard silicone oil in as vitreous tamponade in inferior PVR (HSO Study): interim analysis

Antonia M. Joussen, Stanislao Rizzo, Bernd Kirchhof, Norbert Schrage, Xiaoxin Li, Christina Lente, Ralf-Dieter Hilgers, on behalf of the HSO –Study Group

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2011

Language:

english

File:

PDF, 181 KB

english, 2011

45

Baseline [18F]-FDOPA kinetics are predictive of haloperidol-induced changes in dopamine turnover and cognitive performance: A positron emission tomography study in healthy subjects

Ingo Vernaleken, Yoshitaka Kumakura, Hans-Georg Buchholz, Thomas Siessmeier, Ralf-Dieter Hilgers, Peter Bartenstein, Paul Cumming, Gerhard Gründer

Journal:

Year:

2008

Language:

english

File:

PDF, 691 KB

english, 2008

46

Temporary Pulmonary Stent Placement as Emergency Treatment of Pulmonary Embolism: First Experimental Evaluation

Thomas Schmitz-Rode, Rajeev Verma, Joachim G. Pfeffer, Ralf-Dieter Hilgers, Rolf W. Günther

Journal:

Journal of the American College of Cardiology

Year:

2006

Language:

english

File:

PDF, 267 KB

english, 2006

47

Intrathoracic versus Cervical Anastomosis after Resection of Esophageal Cancer: A matched pair analysis of 72 patients in a single center study

Christian D Klink, Marcel Binnebösel, Jens Otto, Gabriele Boehm, Klaus T von Trotha, Ralf-Dieter Hilgers, Joachim Conze, Ulf P Neumann, Marc Jansen

Journal:

World Journal of Surgical Oncology

Year:

2012

Language:

english

File:

PDF, 149 KB

english, 2012

48

The Neuroprotective Potential of Rho-Kinase Inhibition in Promoting Cell Survival and Reducing Reactive Gliosis in Response to Hypoxia in Isolated Bovine Retina

Alt, Aizhan, Hilgers, Ralf-Dieter, Tura, Aysegül, Nassar, Khaled, Schneider, Toni, Hueber, Arno, Januschowski, Kai, Grisanti, Salvatore, Lüke, Julia, Lüke, Matthias

Journal:

Cellular Physiology and Biochemistry

Year:

2013

Language:

english

File:

PDF, 3.07 MB

english, 2013

49

Microsurgical Free Flap Reconstructions of Head and Neck Region in 406 Cases: A 13-Year Experience

Gerressen, Marcus, Pastaschek, Claudia Inge, Riediger, Dieter, Hilgers, Ralf-Dieter, Hölzle, Frank, Noroozi, Nelson, Ghassemi, Alireza

Journal:

Journal of Oral and Maxillofacial Surgery

Year:

2013

Language:

english

File:

PDF, 960 KB

english, 2013

50

A note on robustness of D-optimal block designs for two-colour microarray experiments

Bailey, R.A., Schiffl, Katharina, Hilgers, Ralf-Dieter

Journal:

Journal of Statistical Planning and Inference

Year:

2013

Language:

english

File:

PDF, 281 KB

english, 2013