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51

Randomized, double-blinded, placebo-controlled study to evaluate the safety, pharmacokinetics, and pharmacodynamics of avagacestat (BMS 708163) in healthy Japanese and non-Japanese subjects

Randy Dockens, Ellen Chung, Oleksandr Sverdlov, Holly Soares, Bing He, Michael Furlong, Gary Tong

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

52

Performance of improved cerebrospinal fluid Aβ42 and tau assays in differentiating Alzheimer's disease and MCI from control subjects

Flora Berisha, Paul Rhyne, Carol Gleason, Pankaj Oberoi, James Wilbur, Jill Dunty, George Green, Robert Neely, Adam Simon, David Stewart, Holly Soares

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 81 KB

english, 2012

53

Novel human CSF tau-fragment and pTau assays for distinguishing Alzheimer's from control subjects

Sethu Sankaranarayanan, Jere Meredith, Valerie Guss, Alan Xu-Lin, Holly Soares, Kaj Blennow, Charles Albright, Michael Ahlijanian

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

54

Randomized, double-blind, placebo-controlled study to evaluate the safety, pharmacokinetics and pharmacodynamics of avagacestat (BMS 708163) in healthy Japanese and non-Japanese subjects

Randy Dockens, Ellen Chung, Oleksandr Sverdlov, Holly Soares, Bing He, Michael Furlong, Gary Tong

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

55

Novel tau fragments are present in human CSF

Jere Meredith, Randall Slemmon, Valerie Guss, Anthony Lanzetti, Sethu Sankaranarayanan, Holly Soares, Kaj Blennow, Charlie Albright, Michael Ahlijanian

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 435 KB

english, 2012

56

Relationship between CSF and plasma proteomic data in the ADNI-1 cohort

Sungeun Kim, Shanker Swaminathan, Kwangsik Ngo, Shannon Risacher, Li Shen, Tatiana Foroud, Leslie Shaw, John Trojanowski, Holly Soares, Michael Weiner, Andrew Saykin

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 259 KB

english, 2012

57

Comparison of CNS homing pattern among murine TH cell lines responsive to myelin basic protein

Elisa Barbarese, Holly Soares, Sharlene Yang, Robert B. Clark

Journal:

Journal of Neuroimmunology

Year:

1992

Language:

english

File:

PDF, 1.40 MB

english, 1992

58

Cerebrospinal fluid β-amyloid1–42 and tau in control subjects at risk for Alzheimer’s disease: The effect of APOE ε4 allele

Trey Sunderland, Nadeem Mirza, Karen T. Putnam, Gary Linker, Deepa Bhupali, Rob Durham, Holly Soares, Lida Kimmel, David Friedman, Judy Bergeson, Gyorgy Csako, James A. Levy, John J. Bartko, Robert M.

Journal:

Biological Psychiatry

Year:

2004

Language:

english

File:

PDF, 273 KB

english, 2004

59

Transcription Factors as Molecular Mediators in Cell Death

HOLLY D. SOARES, TOM CURRAN, JAMES I. MORGAN

Journal:

Annals of the New York Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 667 KB

english, 1994

60

Global standardization measurement of cerebral spinal fluid for Alzheimer's disease: An update from the Alzheimer's Association Global Biomarkers Consortium

Carrillo, Maria C., Blennow, Kaj, Soares, Holly, Lewczuk, Piotr, Mattsson, Niklas, Oberoi, Pankaj, Umek, Robert, Vandijck, Manu, Salamone, Salvatore, Bittner, Tobias, Shaw, Leslie M., Stephenson, Dian

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 309 KB

english, 2013

61

The future of blood-based biomarkers for Alzheimer's disease

Henriksen, Kim, O’Bryant, Sid E., Hampel, Harald, Trojanowski, John Q., Montine, Thomas J., Jeromin, Andreas, Blennow, Kaj, Lönneborg, Anders, Wyss-Coray, Tony, Soares, Holly, Bazenet, Chantal, Sjögre

Journal:

Alzheimer's & Dementia

Year:

2014

Language:

english

File:

PDF, 971 KB

english, 2014

62

Association of plasma C-reactive protein levels with the diagnosis of Alzheimer's disease

Yarchoan, Mark, Louneva, Natalia, Xie, Sharon X., Swenson, Frank J., Hu, William, Soares, Holly, Trojanowski, John Q., Lee, Virginia M.-Y., Kling, Mitchel A., Shaw, Leslie M., Chen-Plotkin, Alice, Wol

Journal:

Journal of the Neurological Sciences

Year:

2013

Language:

english

File:

PDF, 211 KB

english, 2013

63

Biomarker utility in Alzheimer's disease clinical trials

Soares, Holly D., Lovestone, Simon

Journal:

Drug Discovery Today: Therapeutic Strategies

Year:

2013

Language:

english

File:

PDF, 345 KB

english, 2013

64

Discussion

Hwang, Kristy, Lazaris, Andreas, Eastman, Jennifer, Teng, Edmond, Koeppe, Robert, Thompson, Paul, Gylys, Karen, Cole, Greg, Jack, Clifford, Shaw, Leslie, Soares, Holly, Trojanowski, John, Weiner, Mich

Journal:

Journal of Vascular Surgery

Year:

2007

Language:

english

File:

PDF, 45 KB

english, 2007

65

Peripheral blood plasma protein levels are associated with Pittsburgh compound B binding in the brain

Hwang, Kristy, Lazaris, Andreas, Eastman, Jennifer, Teng, Edmond, Koeppe, Robert, Thompson, Paul, Gylys, Karen, Cole, Greg, Jack, Clifford, Shaw, Leslie, Soares, Holly, Trojanowski, John, Weiner, Mich

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 242 KB

english, 2013

66

Reproducibility of a fully automated chemiluminescent tau assay

Tweedie, Anne, Green, George, Soares, Holly, Berisha, Flora, Neely, Robert, Baburina, Irina, Salamone, Salvatore, Kozo, Daniel, Jackson, Shari, Ackles, Karen, Byrne, Deb, DiMagno, Lisa

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

67

BIRMINGHAM WORKHOUSE INFIRMARY.

Ackles, Karen, Green, George, Soares, Holly, Berisha, Flora, Neely, Robert, Baburina, Irina, Salamone, Salvatore, Kozo, Daniel, Jackson, Shari, Tweedie, Anne, Byrne, Deb, DiMagno, Lisa

Journal:

Year:

1889

Language:

english

File:

PDF, 207 KB

english, 1889

68

IRELAND.

Ackles, Karen, Green, George, Soares, Holly, Berisha, Flora, Neely, Robert, Baburina, Irina, Salamone, Salvatore, Kozo, Daniel, Jackson, Shari, Tweedie, Anne, Byrne, Deb, DiMagno, Lisa

Journal:

Year:

1892

Language:

english

File:

PDF, 208 KB

english, 1892

69

Stability performance of a fully automated, chemiluminescent, beta-amyloid 42 assay

Ackles, Karen, Green, George, Soares, Holly, Berisha, Flora, Neely, Robert, Baburina, Irina, Salamone, Salvatore, Kozo, Daniel, Jackson, Shari, Tweedie, Anne, Byrne, Deb, DiMagno, Lisa

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 58 KB

english, 2013

70

Obituary.

Shaw, Leslie M., Vanderstichele, Hugo, Knapik-Czajka, Malgorzata, Blennow, Kaj, Soares, Holly, Simon, Adam, Lewczuk, Piotr, Siemers, Eric, Dean, Robert, Potter, William Z., Lee, Virginia M.-Y., Trojan

Journal:

Year:

1889

Language:

english

File:

PDF, 210 KB

english, 1889

71

P3-093: Characterization of CSF Aβ1-42, Tau and p-Tau181p concentrations at baseline in Alzheimer's disease neuroimaging initiative study patients

Shaw, Leslie M., Vanderstichele, Hugo, Knapik-Czajka, Malgorzata, Blennow, Kaj, Soares, Holly, Simon, Adam, Lewczuk, Piotr, Siemers, Eric, Dean, Robert, Potter, William Z., Lee, Virginia M.-Y., Trojan

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 69 KB

english, 2008

72

Baseline CSF BETA-AMYLOID 42 correlates with ApoE genotype and baseline cognitive status in a phase II avagacestat predementia Alzheimer's disease study

Soares, Holly, Berisha, Flora, Gleason, Carol, Green, George, Tiller, Jane, Piccoli, Stephen, Burns, Leah, Berman, Robert, Kaplita, Stephen, Coric, Vlad

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 55 KB

english, 2012

73

Influence of genetic variation on plasma proteomics in AD, MCI and controls: Pairwise gene-protein analysis in the ADNI-1 cohort

Kim, Sungeun, Swaminathan, Shanker, Inlow, Mark, Risacher, Shannon, Shen, Li, Foroud, Tatiana, Shaw, Leslie, Trojanowski, John, Soares, Holly, Weiner, Michael, Saykin, Andrew

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 170 KB

english, 2011

74

Performance of preliminary cut-points for progression from mild cognitive impairment to dementia of the Alzheimer's disease type using fully automated chemiluminescent beta-amyloid 42 and tau assays

Simon, Adam, Salamone, Salvatore, Clarke, William, Green, George, Soares, Holly, Burns, Leah, Baburina, Irina, Kozo, Daniel, Courtney, Jodi, Contestable, Paul, Jackson, Shari, Ajongwen, Patience

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 55 KB

english, 2013

75

The clinical utility of blood-based biomarkers in Alzheimer's disease

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 46 KB

english, 2013

76

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

Forrest, Douglas, Yuzaki, Michisuke, Soares, Holly D., Ng, Lily, Luk, Daniel C., Sheng, Morgan, Stewart, Colin L., Morgan, James I., Connor, John A., Curran, Tom

Journal:

Year:

1994

Language:

english

File:

PDF, 26.28 MB

english, 1994

77

Performance testing of a fully automated, Chemiluminescent, tau assay

Kozo, Daniel, Green, George, Soares, Holly, Baburina, Irina, Salamone, Salvatore, Courtney, Jodi, Contestable, Paul, Jackson, Shari, Ackles, Karen, Tweedie, Anne

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 76 KB

english, 2013

78

A comparison of hippocampal atrophy algorithms to select outcome measures for clinical trials in mild-to-moderate Alzheimer's disease

Burns, Leah, Rueckert, Daniel, Bhagwagar, Zubin, Donohue, Michael, Wolz, Robin, Tiller, Jane, Soares, Holly, l'Italien, Gilbert, Coric, Vlad, Hayes, Wendy, Fox, Nick, Berman, Robert

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 56 KB

english, 2012

79

Performance testing of a fully automated, Chemiluminescent, beta-amyloid 42 assay

Baburina, Irina, Contestable, Paul, Green, George, Soares, Holly, Jackson, Shari, Ackles, Karen, Tweedie, Anne, Kozo, Daniel, Courtney, Jodi, Salamone, Salvatore

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 163 KB

english, 2013

80

Initial evaluation of fully automated, chemiluminescent beta-amyloid 42 and tau assays

Simon, Adam, Baburina, Irina, Clarke, William, Green, George, Soares, Holly, Salamone, Salvatore, Kozo, Daniel, Courtney, Jodi, Contestable, Paul, Jackson, Shari, Ajongwen, Patience

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 102 KB

english, 2013

81

CSF biomarker qualification

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 45 KB

english, 2011

82

Novel CSF biomarkers for Alzheimer's disease and mild cognitive impairment

Hu, William T., Chen-Plotkin, Alice, Arnold, Steven E., Grossman, Murray, Clark, Christopher M., Shaw, Leslie M., Lee, Virginia M.-Y., Soares, Holly D., Trojanowski, John Q.

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 49 KB

english, 2010

83

P3-255: Matrix metalloproteinase 3 haplotypes and plasma amyloid-beta levels: The Rotterdam study

Reitz, Christiane, van Rooij, Frank, Soares, Holly, de Maat, Moniek, Hofman, Albert, Witteman, Jacqueline, Breteler, Monique

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 198 KB

english, 2008

84

Reproducibility of a fully automated, chemiluminescent, beta-amyloid 42 assay

Jackson, Shari, Green, George, Soares, Holly, Berisha, Flora, Neely, Robert, Baburina, Irina, Kozo, Daniel, Salamone, Salvatore, Tweedie, Anne, Ackles, Karen, Byrne, Deb, DiMagno, Lisa

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 53 KB

english, 2013

85

Multiplex plasma panels as screening tools in Alzheimer's disease.

Soares, Holly, Hu, William, Grossman, Murray, Clark, Chris, Pickering, Eve, Chen, Yu, Kuhn, Max, Chen-Plotkin, Alice, Arnold, Stephen, Shaw, Les, Lee, Virginia M.-Y., Swenson, Frank, Trojanowski, John

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010

86

Peripheral blood plasma protein levels are associated with Pittsburgh compound B-binding in the brain

Hwang, Kristy, Lazaris, Andreas, Eastman, Jennifer, Teng, Edmond, Koeppe, Robert, Thompson, Paul, Gylys, Karen, Cole, Greg, Jack, Clifford, Shaw, Leslie, Soares, Holly, Trojanowski, John, Weiner, Mich

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 329 KB

english, 2013

87

Stability performance of a fully automated, chemiluminescent tau assay for the VITROS® immunodiagnostic systems with cerebrospinal fluid over a 29-week study

DiMagno, Lisa, Jackson, Shari, Tweedie, Anne, Ackles, Karen, Byrne, Deb, Kozo, Daniel, Baburina, Irina, Salamone, Salvatore, Soares, Holly, Berisha, Flora, Neely, Robert, Green, George

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 57 KB

english, 2013

88

Decreased α 1 -Adrenergic Receptors After Experimental Brain Injury

PRASAD, M. RENUKA, TZIGARET, CEZAR M., SMITH, DOUGLAS, SOARES, HOLLY, McINTOSH, TRACY K.

Journal:

Journal of Neurotrauma

Year:

1992

Language:

english

File:

PDF, 3.85 MB

english, 1992

89

Effects of the N -Methyl- d -Aspartate Receptor Blocker MK-801 on Neurologic Function After Experimental Brain Injury

MCINTOSH, TRACY K., VINK, ROBERT, SOARES, HOLLY, HAYES, RONALD, SIMON, ROGER

Journal:

Journal of Neurotrauma

Year:

1989

Language:

english

File:

PDF, 1.36 MB

english, 1989

90

Fetal Hippocampal Transplants Attenuate CA3 Pyramidal Cell Death Resulting from Fluid Percussion Brain Injury in the Rat

SOARES, HOLLY D., SINSON, GRANT P., McINTOSH, TRACY K.

Journal:

Journal of Neurotrauma

Year:

1995

Language:

english

File:

PDF, 6.68 MB

english, 1995

91

Low Plasma ApoE Levels Are Associated with Smaller Hippocampal Size in the Alzheimer's Disease Neuroimaging Initiative Cohort

Teng, Edmond, Chow, Nicole, Hwang, Kristy S., Thompson, Paul M., Gylys, Karen H., Cole, Gregory M., Jack, Clifford R., Shaw, Leslie M., Trojanowski, John Q., Soares, Holly D., Weiner, Michael W., Apos

Journal:

Dementia and Geriatric Cognitive Disorders

Year:

2015

Language:

english

File:

PDF, 1.51 MB

english, 2015

92

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

O'Bryant, Sid E., Gupta, Veer, Henriksen, Kim, Edwards, Melissa, Jeromin, Andreas, Lista, Simone, Bazenet, Chantal, Soares, Holly, Lovestone, Simon, Hampel, Harald, Montine, Thomas, Blennow, Kaj, Foro

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 1.53 MB

english, 2015

93

Stability of CSF β-Amyloid1–42 and Tau Levels by APOE Genotype in Alzheimer Patients

Huey, Edward D., Mirza, Nadeem, Putnam, Karen T., Soares, Holly, Csako, Gyorgy, Levy, James A., Copenhaver, Brittany, Cohen, Robert M., Sunderland, Trey

Journal:

Dementia and Geriatric Cognitive Disorders

Year:

2006

Language:

english

File:

PDF, 180 KB

english, 2006

94

Cholesterol, Copper and Aβ in Controls, MCI, AD and the AD Cholesterol- Lowering Treatment Trial (ADCLT)

Sparks, D., Petanceska, Suzana, Sabbagh, Marwan, Connor, Donald, Soares, Holly, Adler, Charles, Lopez, Jean, Ziolkowski, Chuck, Lochhead, Jeff, Browne, Patrick

Journal:

Current Alzheimer Research

Year:

2005

Language:

english

File:

PDF, 269 KB

english, 2005

95

The Alzheimer’s Disease Neuroimaging Initiative 2 Biomarker Core: A review of progress and plans

Kang, Ju-Hee, Korecka, Magdalena, Figurski, Michal J., Toledo, Jon B., Blennow, Kaj, Zetterberg, Henrik, Waligorska, Teresa, Brylska, Magdalena, Fields, Leona, Shah, Nirali, Soares, Holly, Dean, Rober

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 2.02 MB

english, 2015

96

[International Review of Neurobiology] Human Brain Proteome Volume 61 || Proteomic Approaches in Drug Discovery and Development

Soares, Holly D.

Year:

2004

Language:

english

File:

PDF, 786 KB

english, 2004

97

The path to regulatory qualification of cerebrospinal fluid biomarkers as enrichment tools in clinical trials of patients with early Alzheimer’s disease: For the coalition against major diseases

Vanderstichele, Hugo Marcel, Stephenson, Diane, Shaw, Leslie M., Carrillo, Maria, Umek, Robert, Rajapakse, Hemaka, Luthman, Johan, Soares, Holly, Gordon, Mark Forrest, Devanarayan, Viswanath, Genius,

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 149 KB

english, 2015

98

BIOMARKER STABILITY IN CSF: PRE-ANALYTICAL FACTORS IN A PROSPECTIVE COLLECTION

Kozo, Daniel R., Salamone, Salvatore J., Baburina, Irina, Williams, Kim, Baldasano, Caitlin N., Courtney, Jodi, Green, George, Soares, Holly D., Feiss, Gary, Simon, Adam J.

Journal:

Alzheimer's & Dementia

Year:

2014

Language:

english

File:

PDF, 54 KB

english, 2014

99

Genetic findings using ADNI multimodal quantitative phenotypes: A 2014 update

Yao, Xiaohui, Yan, Jingwen, Kim, Sungeun, Nho, Kwangsik, Risacher, Shannon L., Börner, Katy, Foroud, Tatiana M., Thompson, Paul M., Potkin, Steven G., Sarwar, Nadeem, Munsie, Leanne, Soares, Holly, Gr

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 221 KB

english, 2015

100

Gene expression profiling identifies altered networks in late-onset Alzheimer’s disease: Immune response and mitochondrial process

Nho, Kwangsik, Kim, Sungeun, Risacher, Shannon L., Soares, Holly, Singh, Parul, Wang, Lisu, Qi, Zhenhao, He, Aiqing, Neuhaus, Isaac, Patel, Vishal, Kim, Dokyoon, Foroud, Tatiana M., Faber, Kelly, Apos

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 731 KB

english, 2015