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1

Establishing best practise in the application of expert review of mutagenicity under ICH M7

Barber, Chris, Amberg, Alexander, Custer, Laura, Dobo, Krista L., Glowienke, Susanne, Van Gompel, Jacky, Gutsell, Steve, Harvey, Jim, Honma, Masamitsu, Kenyon, Michelle O., Kruhlak, Naomi, Muster, Wol

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

2

Application of DNA Fingerprinting to Parentage and Extended Family Relationship Testing

Honma, Masamitsu, Ishiyama, Ikuo

Journal:

Year:

1990

Language:

english

File:

PDF, 822 KB

english, 1990

3

Review: Biological effects of space environmental factors: A possible interaction between space radiation and microgravity

Yatagai, Fumio, Honma, Masamitsu, Dohmae, Naoshi, Ishioka, Noriaki

Journal:

Life Sciences in Space Research

Year:

2018

Language:

english

File:

PDF, 2.93 MB

english, 2018

4

A comparative study of TK6 human lymphoblastoid and L5178Y mouse lymphoma cell lines in the in vitro micronucleus test

Li-Shi Zhang, Masamitsu Honma, Makoto Hayahshi, Takayoshi Suzuki, Atsuko Matsuoka, Toshio Sofuni

Journal:

Mutation Research Letters

Year:

1995

Language:

english

File:

PDF, 524 KB

english, 1995

5

Summary of major conclusions from the 6th International Workshop on Genotoxicity Testing (IWGT), Foz do Iguaçu, Brazil

Martus, Hans-Joerg, Hayashi, Makoto, Honma, Masamitsu, Kasper, Peter, Gollapudi, Bhaskar, Mueller, Lutz, Schoeny, Rita, Uno, Yoshifumi, Kirkland, David J.

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2015

Language:

english

File:

PDF, 295 KB

english, 2015

6

Evaluation of the sensitivity and specificity of in vivo erythrocyte micronucleus and transgenic rodent gene mutation tests to detect rodent carcinogens

Morita, Takeshi, Hamada, Shuichi, Masumura, Kenichi, Wakata, Akihiro, Maniwa, Jiro, Takasawa, Hironao, Yasunaga, Katsuaki, Hashizume, Tsuneo, Honma, Masamitsu

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2016

Language:

english

File:

PDF, 1.71 MB

english, 2016

7

Mutagenicity of ω-3 fatty acid peroxidation products in the Ames test

Grúz, Petr, Shimizu, Masatomi, Sugiyama, Kei-ichi, Honma, Masamitsu

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2017

Language:

english

File:

PDF, 641 KB

english, 2017

8

In silico prediction of chromosome damage: comparison of three (Q)SAR models

Morita, Takeshi, Shigeta, Yoshiyuki, Kawamura, Tomoko, Fujita, Yurika, Honda, Hiroshi, Honma, Masamitsu

Journal:

Year:

2018

Language:

english

File:

PDF, 158 KB

english, 2018

9

Summarized data of genotoxicity tests for designated food additives in Japan

Yamada, Masami, Honma, Masamitsu

Journal:

Genes and Environment

Year:

2018

Language:

english

File:

PDF, 460 KB

english, 2018

10

Screening for Ames mutagenicity of food flavor chemicals by (quantitative) structure-activity relationship

Honma, Masamitsu, Kitazawa, Airi, Kasamatsu, Toshio, Sugiyama, Kei-ichi

Journal:

Genes and Environment

Year:

2020

File:

PDF, 1.04 MB

2020

11

Mouse lymphoma workshop: Victoria, British Columbia, Canada, March 27, 1996 Protocol issues regarding the use of the microwell method of the mouse lymphoma assay

Toshio Sofuni, Philip Wilcox, Hiroyasu Shimada, Julie Clements, Masamitsu Honma, Donald Clive, Michael Green, Veronique Thybaud, Richard H.C. San, Barry M. Elliott, Lutz Müller

Journal:

Environmental and Molecular Mutagenesis

Year:

1997

Language:

english

File:

PDF, 42 KB

english, 1997

12

Mouse lymphoma thymidine kinase locus gene mutation assay: International Workshop on Genotoxicity Test Procedures Workgroup report

Martha M. Moore, Masamitsu Honma, Julie Clements, Takumi Awogi, George Bolcsfoldi, Jane Cole, Bhaskar Gollapudi, Karen Harrington-Brock, Ann Mitchell, Wolfgang Muster, Brian Myhr, Michael O'Donovan, M

Journal:

Environmental and Molecular Mutagenesis

Year:

2000

Language:

english

File:

PDF, 53 KB

english, 2000

13

Requirement of wild-type p53 protein for maintenance of chromosomal integrity

Masamitsu Honma, Maki Momose, Hideyuki Tanabe, Hiroko Sakamoto, Yongjia Yu, John B. Little, Toshio Sofuni, Makoto Hayashi

Journal:

Molecular Carcinogenesis

Year:

2000

Language:

english

File:

PDF, 398 KB

english, 2000

14

Phenotypic heterogeneity of an adult form of adrenoleukodystrophy in monozygotic twins

Gen Sobue, Ikuko Ueno-Natsukari, Hideki Okamoto, Thomas A. Connell, Izumi Aizawa, Koichi Mizoguchi, Masamitsu Honma, Gen Ishikawa, Terunori Mitsuma, Dr. Naoki Natsukari

Journal:

Annals of Neurology

Year:

1994

Language:

english

File:

PDF, 450 KB

english, 1994

15

Mouse lymphoma thymidine kinase gene mutation assay: Follow-up International Workshop on Genotoxicity Test Procedures, New Orleans, Louisiana, April 2000

Martha M. Moore, Masamitsu Honma, Julie Clements, Karen Harrington-Brock, Takumi Awogi, George Bolcsfoldi, Maria Cifone, Deborah Collard, Michael Fellows, Kathryn Flanders, Bhaskar Gollapudi, Peter Je

Journal:

Environmental and Molecular Mutagenesis

Year:

2002

Language:

english

File:

PDF, 176 KB

english, 2002

16

Deletion, rearrangement, and gene conversion; genetic consequences of chromosomal double-strand breaks in human cells

Masamitsu Honma, Masako Izumi, Mayumi Sakuraba, Satoshi Tadokoro, Hiroko Sakamoto, Wensheng Wang, Fumio Yatagai, Makoto Hayashi

Journal:

Environmental and Molecular Mutagenesis

Year:

2003

Language:

english

File:

PDF, 338 KB

english, 2003

17

DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3-nitrobenzanthrone in Muta Mouse

Volker M. Arlt, Li Zhan, Heinz H. Schmeiser, Masamitsu Honma, Makoto Hayashi, David H. Phillips, Takayoshi Suzuki

Journal:

Environmental and Molecular Mutagenesis

Year:

2004

Language:

english

File:

PDF, 156 KB

english, 2004

18

Generation of loss of heterozygosity and its dependency on p53 status in human lymphoblastoid cells

Masamitsu Honma

Journal:

Environmental and Molecular Mutagenesis

Year:

2005

Language:

english

File:

PDF, 390 KB

english, 2005

19

Mouse lymphoma thymidine kinase gene mutation assay: Follow-up meeting of the international workshop on Genotoxicity testing—Aberdeen, Scotland, 2003—Assay acceptance criteria, positive controls, and data evaluation

Martha M. Moore, Masamitsu Honma, Julie Clements, George Bolcsfoldi, Brian Burlinson, Maria Cifone, Jane Clarke, Robert Delongchamp, Robert Durward, Michael Fellows, Bhaskar Gollapudi, Saimei Hou, Pet

Journal:

Environmental and Molecular Mutagenesis

Year:

2006

Language:

english

File:

PDF, 75 KB

english, 2006

20

3′-azido-3′-deoxythymidine induces deletions in L5178Y mouse lymphoma cells

Jianyong Wang, Tao Chen, Masamitsu Honma, Ling Chen, Martha M. Moore

Journal:

Environmental and Molecular Mutagenesis

Year:

2007

Language:

english

File:

PDF, 207 KB

english, 2007

21

Dependence of DNA double strand break repair pathways on cell cycle phase in human lymphoblastoid cells

Yoshio Takashima, Mayumi Sakuraba, Tomoko Koizumi, Hiroko Sakamoto, Makoto Hayashi, Masamitsu Honma

Journal:

Environmental and Molecular Mutagenesis

Year:

2009

Language:

english

File:

PDF, 219 KB

english, 2009

22

Genotoxicity of acrylamide in vitro: Acrylamide is not metabolically activated in standard in vitro systems

Naoki Koyama, Manabu Yasui, Yoshimitsu Oda, Satoshi Suzuki, Tetsuo Satoh, Takuya Suzuki, Tomonari Matsuda, Shuichi Masuda, Naohide Kinae, Masamitsu Honma

Journal:

Environmental and Molecular Mutagenesis

Year:

2011

Language:

english

File:

PDF, 550 KB

english, 2011

23

Comparison of in vitro micronucleus and gene mutation assay results for p53-competent versus p53-deficient human lymphoblastoid cells

Masamitsu Honma, Makoto Hayashi

Journal:

Environmental and Molecular Mutagenesis

Year:

2011

Language:

english

File:

PDF, 285 KB

english, 2011

24

Further development of the rat Pig-a mutation assay: Measuring rat Pig-a mutant bone marrow erythroids and a high throughput assay for mutant peripheral blood reticulocytes

Takafumi Kimoto, Satsuki Chikura, Kumiko Suzuki, Xiao mei Kobayashi, Yasuhiro Itano, Katsuyoshi Horibata, Masamitsu Honma, Vasily N. Dobrovolsky, Robert H. Heflich, Daishiro Miura, Yoshinori Kasahara

Journal:

Environmental and Molecular Mutagenesis

Year:

2011

Language:

english

File:

PDF, 834 KB

english, 2011

25

Hardness distribution on wood surface

Seiji Hirata, Masamitsu Ohta, Yasuo Honma

Journal:

Journal of Wood Science

Year:

2001

Language:

english

File:

PDF, 1.38 MB

english, 2001

26

Life stage-related differences in susceptibility to acrylamide-induced neural and testicular toxicity

Miwa Takahashi, Kaoru Inoue, Naoki Koyama, Midori Yoshida, Kaoru Irie, Tomomi Morikawa, Makoto Shibutani, Masamitsu Honma, Akiyoshi Nishikawa

Journal:

Archives of Toxicology

Year:

2011

Language:

english

File:

PDF, 869 KB

english, 2011

27

Repair of I-SceI Induced DSB at a specific site of chromosome in human cells: influence of low-dose, low-dose-rate gamma-rays

Fumio Yatagai, Masao Suzuki, Noriaki Ishioka, Hitoshi Ohmori, Masamitsu Honma

Journal:

Radiation and Environmental Biophysics

Year:

2008

Language:

english

File:

PDF, 269 KB

english, 2008

28

Frozen human cells can record radiation damage accumulated during space flight: mutation induction and radioadaptation

Fumio Yatagai, Masamitsu Honma, Akihisa Takahashi, Katsunori Omori, Hiromi Suzuki, Toru Shimazu, Masaya Seki, Toko Hashizume, Akiko Ukai, Kaoru Sugasawa, Tomoko Abe, Naoshi Dohmae, Shuichi Enomoto, Ta

Journal:

Radiation and Environmental Biophysics

Year:

2011

Language:

english

File:

PDF, 458 KB

english, 2011

29

Sarcoidosis development during induction chemotherapy for lung cancer mimicked progressive disease

Hideo Umezu, Masayuki Chida, Takashi Inoue, Osamu Araki, Motohiko Tamura, Masamitsu Tatewaki, Yasutsugu Fukushima, Koichi Honma

Journal:

General Thoracic and Cardiovascular Surgery

Year:

2010

Language:

english

File:

PDF, 388 KB

english, 2010

30

Engagement of CD47 Inhibits the Contact Hypersensitivity Response Via the Suppression of Motility and B7 Expression by Langerhans Cells

Yu, Xijun, Fukunaga, Atsushi, Nagai, Hiroshi, Oniki, Shuntaro, Honma, Nakayuki, Ichihashi, Masamitsu, Matozaki, Takashi, Nishigori, Chikako, Horikawa, Tatsuya

Journal:

The Journal of Investigative Dermatology

Year:

2006

Language:

english

File:

PDF, 336 KB

english, 2006

31

Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex

Katsuyoshi Horibata, Masafumi Saijo, Mui N. Bay, Li Lan, Isao Kuraoka, Philip J. Brooks, Masamitsu Honma, Takehiko Nohmi, Akira Yasui, Kiyoji Tanaka

Journal:

Year:

2011

Language:

english

File:

PDF, 800 KB

english, 2011

32

A new DNA profiling system for cell line identification for use in cell banks in Japan

Masamitsu Honma, Eiko Kataoka, Kiyokata Ohnishi, Tadao Ohno, Masao Takeuchi, Nobuo Nomura, Hiroshi Mizusawa

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1992

Language:

english

File:

PDF, 496 KB

english, 1992

33

Application of highly polymorphic dna markers to the identification of hela cell sublines

Eiko Kataoka, Masamitsu Honma, Kiyokata Ohnishi, Toshio Sofuni, Hiroshi Mizusawa

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1992

Language:

english

File:

PDF, 381 KB

english, 1992

34

Heterogeneity of the Y chromosome following long-term culture of the human lung cancer cell line A549

Masamitsu Honma, Makoto Hayashi, Tadao Ohno, Hiroshi Mizusawa, Kaoru Saijo, Toshio Sofuni

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1996

Language:

english

File:

PDF, 1.27 MB

english, 1996

35

Detection of recombinational mutations in cultured human cells by Southern blot analysis with minisatellite DNA probes

Masamitsu Honma, Eiko Kataoka, Kiyokata Ohnishi, Tsukasa Kikuno, Makoto Hayashi, Toshio Sofuni, Hiroshi Mizusawa

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1993

Language:

english

File:

PDF, 699 KB

english, 1993

36

Demonstration by DNA fingerprint analysis of genomic instability in mouse BALB 3T3 cells during cell transformation

Masamitsu Honma, Hiroshi Mizusawa, Kiyoshi Sasaki, Makoto Hayashi, Tadao Ohno, Noriho Tanaka, Toshio Sofuni

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1994

Language:

english

File:

PDF, 2.80 MB

english, 1994

37

Isolation of micronuclei from mouse blood and fluorescence in situ hybridization with a mouse centromeric DNA probe

Makoto Hayashi, Jorma Mäki-Paakkanen, Hideyuki Tanabe, Masamitsu Honma, Takayoshi Suzuki, Atsuko Matsuoka, Hiroshi Mizusawa, Toshio Sofuni

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1994

Language:

english

File:

PDF, 524 KB

english, 1994

38

DNA fingerprint analysis in chemically mutagenized Chinese hamster lung cells

Tsukasa Kikuno, Masamitsu Honma, Syozo Ogura, Hiroshi Mizusawa, Makoto Hayashi, Toshio Sofuni

Journal:

Mutation Research/DNAging

Year:

1995

Language:

english

File:

PDF, 587 KB

english, 1995

39

Mutagenic radioadaptation in a human lymphoblastoid cell line

Fumio Yatagai, Yukihiro Umebayashi, Masamitsu Honma, Kaoru Sugasawa, Yuko Takayama, Fumio Hanaoka

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2008

Language:

english

File:

PDF, 562 KB

english, 2008

40

Live cell imaging of micronucleus formation and development

Manabu Yasui, Naoki Koyama, Tomoko Koizumi, Kaori Senda-Murata, Yoshio Takashima, Makoto Hayashi, Kenji Sugimoto, Masamitsu Honma

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2010

Language:

english

File:

PDF, 1.48 MB

english, 2010

41

Involvement of mismatch repair proteins in adaptive responses induced by N-methyl-N′-nitro-N-nitrosoguanidine against γ-induced genotoxicity in human cells

Ayumi Yamamoto, Yasuteru Sakamoto, Kenichi Masumura, Masamitsu Honma, Takehiko Nohmi

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

42

Cytotoxic and mutagenic responses to X-rays and chemical mutagens in normal and p53-mutated human lymphoblastoid cells

Masamitsu Honma, Makoto Hayashi, Toshio Sofuni

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 421 KB

english, 1997

43

P VIII.5 - P VIII.5 Genomic instability by mutant p53 leading to allelic loss and translocation via illegitimate recombination

Masamitsu Honma, Li-Shi Zhang, Makoto Hayashi, Kenji Takeshita, Yuzuki Nakagawa, Noriho Tanaka, Toshio Sofuni

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 119 KB

english, 1997

44

The absence of a functional relationship between ATM and BLM, the components of BASC, in DT40 cells

Wensheng Wang, Masayuki Seki, Makoto Otsuki, Shusuke Tada, Noriaki Takao, Ken-ichi Yamamoto, Makoto Hayashi, Masamitsu Honma, Takemi Enomoto

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2004

Language:

english

File:

PDF, 480 KB

english, 2004

45

Non-homologous end-joining for repairing I-SceI-induced DNA double strand breaks in human cells

Masamitsu Honma, Mayumi Sakuraba, Tomoko Koizumi, Yoshio Takashima, Hiroko Sakamoto, Makoto Hayashi

Journal:

Year:

2007

Language:

english

File:

PDF, 1.46 MB

english, 2007

46

Validation of the (Q)SAR combination approach for mutagenicity prediction of flavor chemicals

Atsushi Ono, Mika Takahashi, Akihiko Hirose, Eiichi Kamata, Tomoko Kawamura, Takeshi Yamazaki, Kyoko Sato, Masami Yamada, Takayuki Fukumoto, Hiroyuki Okamura, Yoshiharu Mirokuji, Masamitsu Honma

Journal:

Food and Chemical Toxicology

Year:

2012

Language:

english

File:

PDF, 257 KB

english, 2012

47

Miscoding Properties of 2′-Deoxyinosine, a Nitric Oxide-Derived DNA Adduct, during Translesion Synthesis Catalyzed by Human DNA Polymerases

Manabu Yasui, Emi Suenaga, Naoki Koyama, Chikahide Masutani, Fumio Hanaoka, Petr Gruz, Shinya Shibutani, Takehiko Nohmi, Makoto Hayashi, Masamitsu Honma

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 651 KB

english, 2008

48

Mutational Specificities of Brominated DNA Adducts Catalyzed by Human DNA Polymerases

Akira Sassa, Toshihiro Ohta, Takehiko Nohmi, Masamitsu Honma, Manabu Yasui

Journal:

Journal of Molecular Biology

Year:

2011

Language:

english

File:

PDF, 420 KB

english, 2011

49

Genotoxicity of microcystin-LR in human lymphoblastoid TK6 cells

Li Zhan, Hiroko Sakamoto, Mayumi Sakuraba, De-Sheng Wu, Li-Shi Zhang, Takayoshi Suzuki, Makoto Hayashi, Masamitsu Honma

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2004

Language:

english

File:

PDF, 87 KB

english, 2004

50

Mouse Lymphoma Thymidine Kinase Gene Mutation Assay: International Workshop on Genotoxicity Tests Workgroup Report—Plymouth, UK 2002

Martha M Moore, Masamitsu Honma, Julie Clements, George Bolcsfoldi, Maria Cifone, Robert Delongchamp, Michael Fellows, Bhaskar Gollapudi, Peter Jenkinson, Paul Kirby, Stephan Kirchner, Wolfgang Muster

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2003

Language:

english

File:

PDF, 231 KB

english, 2003