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51

When is an optimization not an optimization? Evaluation of clinical implications of information content (signal-to-noise ratio) in optimization of cardiac resynchronization therapy, and how to measure and maximize it

Punam A. Pabari, Keith Willson, Berthold Stegemann, Irene E. van Geldorp, Andreas Kyriacou, Michela Moraldo, Jamil Mayet, Alun D. Hughes, Darrel P. Francis

Journal:

Heart Failure Reviews

Year:

2011

Language:

english

File:

PDF, 944 KB

english, 2011

52

The clinical assessment of retinal microvascular structure and therapeutic implications

Journal:

Current Treatment Options in Cardiovascular Medicine

Year:

2007

Language:

english

File:

PDF, 121 KB

english, 2007

53

A computational study on the influence of catheter-delivered intravascular probes on blood flow in a coronary artery model

Ryo Torii, Nigel B. Wood, Alun D. Hughes, Simon A. Thom, Jazmin Aguado-Sierra, Justin E. Davies, Darrel P. Francis, Kim H. Parker, X. Yun. Xu

Journal:

Journal of Biomechanics

Year:

2007

Language:

english

File:

PDF, 713 KB

english, 2007

54

Investigating the effects of NSAIDs on the expression of regulatory components of the polyamine pathway

Fiona R. Saunders, Alun Hughes, Heather M. Wallace

Journal:

Year:

2008

Language:

english

File:

PDF, 109 KB

english, 2008

55

ENHANCED TISSUE POLYAMINE CONTENT IN THE SPONTANEOUSLY HYPERTENSIVE RAT

Jamila Ibrahim, Alun D Hughes, Michael Schachter, Peter S Sever

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

1996

Language:

english

File:

PDF, 632 KB

english, 1996

56

DRUG EFFECTS ON THE MECHANICAL PROPERTIES OF LARGE ARTERIES IN HUMANS

Sarah A Hope, Alun D Hughes

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2007

Language:

english

File:

PDF, 84 KB

english, 2007

57

Live imaging of altered period1 expression in the suprachiasmatic nuclei of Vipr2−/− mice

Alun T. L. Hughes, Clare Guilding, Laura Lennox, Rayna E. Samuels, Douglas G. McMahon, Hugh D. Piggins

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 903 KB

english, 2008

58

Maximizing Efficiency of Alternation Algorithms for Hemodynamic Optimization of the AV Delay of Cardiac Resynchronization Therapy

ZACHARY I. WHINNETT, GEMMA NOTT, JUSTIN E. R. DAVIES, KEITH WILLSON, CHARLOTTE H. MANISTY, PRAPA KANAGARATNAM, NICHOLAS S. PETERS, D. WYN DAVIES, ALUN D. HUGHES, JAMIL MAYET, DARREL P. FRANCIS

Journal:

Pacing and Clinical Electrophysiology

Year:

2011

Language:

english

File:

PDF, 226 KB

english, 2011

59

Genetic and Early Life Influences on the Human Retinal Microcirculation

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2012

Language:

english

File:

PDF, 168 KB

english, 2012

60

A Novel in Vitro Model of Conditionally Immortalized Human Vascular Smooth Muscle Cells: A Tool for Aging Studies

HARRIS PRATSINIS, CATHERINE DEMOLIOU-MASON, ALUN HUGHES, DIMITRIS KLETSAS

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 1.25 MB

english, 2000

61

Liquid Drops on the Same Liquid Surface.

HUGHES, WILLIAM, HUGHES, ALUN R.

Journal:

Year:

1932

File:

PDF, 172 KB

1932

62

An Evaluation of the Available Techniques for the Autoradiography of Tritium on Chromatograms

CHAMBERLAIN, J., HUGHES, ALUN, ROGERS, A. W., THOMAS, G. H.

Journal:

Year:

1964

File:

PDF, 251 KB

1964

63

A fossil skull probably of the genus Homo from Sterkfontein, Transvaal

Hughes, Alun R., Tobias, Phillip V.

Journal:

Year:

1977

File:

PDF, 507 KB

1977

64

Melanopsin cells are the principal conduits for rod–cone input to non-image-forming vision

Güler, Ali D., Ecker, Jennifer L., Lall, Gurprit S., Haq, Shafiqul, Altimus, Cara M., Liao, Hsi-Wen, Barnard, Alun R., Cahill, Hugh, Badea, Tudor C., Zhao, Haiqing

Journal:

Year:

2008

Language:

english

File:

PDF, 1.22 MB

english, 2008

65

Action of ryanodine on neurogenic responses in rat isolated mesenteric small arteries

Robinder S. Garcha, Alun D. Hughes

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 322 KB

english, 1997

66

Characterization of [3H]-heparin binding in human vascular smooth muscle cells and its relationship to the inhibition of DNA synthesis

Mahendra K Patel, Jonathan S Refson, Michael Schachter, Alun D Hughes

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 167 KB

english, 1999

67

Action of AT1 receptor antagonists on angiotensin II-induced tone in human isolated subcutaneous resistance arteries

Robinder S Garcha, Peter S Sever, Alun D Hughes

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 187 KB

english, 1999

68

In vivo evidence for KCa channel opening properties of acetazolamide in the human vasculature

Peter Pickkers, Alun D Hughes, Frans G M Russel, Theo Thien, Paul Smits

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 160 KB

english, 2001

69

Mechanism of action of angiotensin II in human isolated subcutaneous resistance arteries

Robinder S Garcha, Peter S Sever, Alun D Hughes

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 216 KB

english, 2001

70

Effect of serum withdrawal on the contribution of L-type calcium channels (CaV1.2) to intracellular Ca2+ responses and chemotaxis in cultured human vascular smooth muscle cells

Mahendra K Patel, Gerard F Clunn, Joanne S Lymn, Oneka Austin, Alun D Hughes

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 187 KB

english, 2005

71

Structural plasticity in the oestrogen receptor ligand-binding domain

Dilis, Robert, Hanson, Robert N, Nettles, Kendall W, Bruning, John B, Gil, German, O'Neill, Erin E, Nowak, Jason, Hughs, Alun, Kim, Younchang, DeSombre, Eugene R

Journal:

Year:

2007

Language:

english

File:

PDF, 232 KB

english, 2007

72

Introduction

Singer, Donald RJ, Cappuccio, Francesco P, Carter, Nicholas D, Hughes, Alun D

Journal:

Journal of Human Hypertension

Year:

2000

Language:

english

File:

PDF, 67 KB

english, 2000

73

Determinants of Retinal Microvascular Architecture in Normal Subjects

ALUN D. HUGHES, TIEN Y. WONG, NICHOLAS WITT, RICHARD EVANS, SIMON A. MCG. THOM, BARBARA E. KLEIN, NISH CHATURVEDI, RONALD KLEIN

Journal:

Microcirculation

Year:

2009

Language:

english

File:

PDF, 175 KB

english, 2009

74

Genetic research and testing in sport and exercise science: A review of the issues

Wackerhage, Henning, Miah, Andy, Harris, Roger C., Montgomery, Hugh E., Williams, Alun G.

Journal:

Journal of Sports Sciences

Year:

2009

Language:

english

File:

PDF, 116 KB

english, 2009

75

Action of heparin and ruthenium red on responses of reversibly-permeabilised rat mesenteric arteries

Robinder S. Garcha, Alun D. Hughes

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1994

Language:

english

File:

PDF, 714 KB

english, 1994

76

Effects of vasoactive agents on intracellular calcium and force in myometrial and subcutaneous resistance arteries isolated from preeclamptic, pregnant, and nonpregnant woman

Ruwan C. Wimalasundera, Simon A. McG. Thom, Lesley Regan, Alun D. Hughes

Journal:

American Journal of Obstetrics and Gynecology

Year:

2005

Language:

english

File:

PDF, 271 KB

english, 2005

77

Can a Statin Neutralize the Cardiovascular Risk of Unhealthy Dietary Choices?

Emily A. Ferenczi, Perviz Asaria, Alun D. Hughes, Nishi Chaturvedi, Darrel P. Francis

Journal:

The American Journal of Cardiology

Year:

2010

Language:

english

File:

PDF, 597 KB

english, 2010

78

Antiphase oscillations of endothelium and smooth muscle [Ca2+]i in vasomotion of rat mesenteric small arteries

Awahan Rahman, Alun Hughes, Vladimir Matchkov, Holger Nilsson, Christian Aalkjær

Journal:

Year:

2007

Language:

english

File:

PDF, 888 KB

english, 2007

79

Development of lysolipid-based thermosensitive liposomes for delivery of high molecular weight proteins

Xin Zhang, Paul F. Luckham, Alun D. Hughes, Simon Thom, Xiao Yun Xu

Journal:

International Journal of Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 144 KB

english, 2011

80

Inhibition of Src family tyrosine kinases prevents lipopolysaccharide-induced hyporeactivity in isolated rat tail arteries

Matthijs Kox, Sumangali Wijetunge, Peter Pickkers, Alun D. Hughes

Journal:

Vascular Pharmacology

Year:

2007

Language:

english

File:

PDF, 263 KB

english, 2007

81

Endothelial Von Willebrand factor regulates angiogenesis

Richard D. Starke, Koralia E. Paschalaki, Francesco Ferraro, Nicola H. Dryden, Thomas A.J. McKinnon, Rachel E. Sutton, Elspeth M. Payne, Dorian O. Haskard, Alun D. Hughes, Daniel F. Cutler, Mike A. La

Journal:

Vascular Pharmacology

Year:

2012

Language:

english

File:

PDF, 63 KB

english, 2012

82

Immunocytochemical appearance of cytokines, prostaglandin E2 and lipocortin-1 in the CNS during the incubation period of murine scrapie correlates with progressive PrP accumulations

Alun Williams, Anne-Marie Van Dam, Diane Ritchie, Pieter Eikelenboom, Hugh Fraser

Journal:

Year:

1997

Language:

english

File:

PDF, 1.28 MB

english, 1997

83

Only weak vasorelaxant properties of loop diuretics in isolated resistance arteries from man, rat and guinea pig

Peter Pickkers, Frans G.M. Russel, Theo Thien, Alun D. Hughes, Paul Smits

Journal:

European Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 202 KB

english, 2003

84

Quantification and characterisation of arteries in retinal images

Xiaohong W. Gao, Anil Bharath, Alice Stanton, Alun Hughes, Neil Chapman, Simon Thom

Journal:

Computer Methods and Programs in Biomedicine

Year:

2000

Language:

english

File:

PDF, 1.13 MB

english, 2000

85

Fully Automatable, Reproducible, Noninvasive Simple Plethysmographic Optimization: Proof of Concept and Potential for Implantability

ANDREAS KYRIACOU, PUNAM A. PABARI, ZACHARY I. WHINNETT, SATPAL ARRI, KEITH WILLSON, RESHAM BARUAH, BERTHOLD STEGEMANN, JAMIL MAYET, PRAPA KANAGARATNAM, ALUN D. HUGHES, DARREL P. FRANCIS

Journal:

Pacing and Clinical Electrophysiology

Year:

2012

Language:

english

File:

PDF, 6.39 MB

english, 2012

86

Attenuation of microvascular function in those with cardiovascular disease is similar in patients of Indian Asian and European descent

William D Strain, Alun D Hughes, Jamil Mayet, Andrew R Wright, Jaspal Kooner, Nish Chaturvedi, Angela C Shore

Journal:

BMC Cardiovascular Disorders

Year:

2010

Language:

english

File:

PDF, 185 KB

english, 2010

87

Should thyroid function be assessed before cardiopulmonary bypass operations?

T.Hugh Jones, Steven M. Hunter, Alun Price, Gianni D. Angelini

Journal:

The Annals of Thoracic Surgery

Year:

1994

Language:

english

File:

PDF, 437 KB

english, 1994

88

Specific binding of 125I SCH 23982, a selective dopamine (D1) receptor ligand to plasma membranes derived from human kidney cortex

Alun Hughes, Peter Sever

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 536 KB

english, 1989

89

Mechanisms involved in the regulation of steroid receptor levels

Peter W. Jungblut, Alun Hughes, Jürgen Gaues, Erhard Kallweit, Itzhak Maschler, Fritz Parl, Walter Sierralta, Pablo I. Szendro, Rüdiger K. Wagner

Journal:

Journal of Steroid Biochemistry

Year:

1979

Language:

english

File:

PDF, 725 KB

english, 1979

90

Estrogen receptor binding affinity and uterotrophic activity of triphenylhaloethylenes

Eugene R. DeSombre, Ronnie C. Mease, Jigi Sanghavl, Tej Singh, Robert H. Seevers, Alun Hughes

Journal:

Journal of Steroid Biochemistry

Year:

1988

Language:

english

File:

PDF, 929 KB

english, 1988

91

Comparison of the distribution of radioiodinated di- and tri-hydroxyphenylethylene estrogens in the immature female rat

Eugene R. Desombre, James Pribish, Alun Hughes

Journal:

Nuclear Medicine and Biology

Year:

1995

Language:

english

File:

PDF, 891 KB

english, 1995

92

Hemodynamic determinants of carotid artery structure in essential hypertension

Ben Ariff, Andrew Zambanini, Vamadeva Sarita, Dean Barratt, Yun Xu, Peter Sever, Nish Chaturvedi, Alice Stanton, Simon Thom, Alun Hughes

Journal:

American Journal of Hypertension

Year:

2004

Language:

english

File:

PDF, 60 KB

english, 2004

93

Wave Propagation and Reflection in the Canine Aorta: Analysis Using a Reservoir-Wave Approach

Jiun-Jr Wang, Nigel G. Shrive, Kim H. Parker, Alun D. Hughes, John V. Tyberg

Journal:

Canadian Journal of Cardiology

Year:

2011

File:

PDF, 3.13 MB

2011

94

Efficiency, reproducibility and agreement of five different hemodynamic measures for optimization of cardiac resynchronization therapy

Zachary I. Whinnett, Justin E.R. Davies, Gemma Nott, Keith Willson, Charlotte H. Manisty, Nicholas S. Peters, Prapa Kanagaratnam, D. Wyn Davies, Alun D. Hughes, Jamil Mayet, Darrel P. Francis

Journal:

International Journal of Cardiology

Year:

2008

Language:

english

File:

PDF, 1.14 MB

english, 2008

95

South Asian men have different patterns of coronary artery disease when compared with European men

Therese Tillin, Harshil Dhutia, John Chambers, Iqbal Malik, Emma Coady, Jamil Mayet, Andrew R. Wright, Jaspal Kooner, Angela Shore, Simon Thom, Nish Chaturvedi, Alun Hughes

Journal:

International Journal of Cardiology

Year:

2008

Language:

english

File:

PDF, 255 KB

english, 2008

96

Normal asynchrony of left ventricular long and short axes: Their relationship with aortic hemodynamics

Chloe M.L. Page, Ashraf W. Khir, Alun D. Hughes, Robin Chung, Michael Y. Henein

Journal:

International Journal of Cardiology

Year:

2010

Language:

english

File:

PDF, 477 KB

english, 2010

97

Calcium channel regulation in vascular smooth muscle cells: Synergistic effects of statins and calcium channel blockers

Gerard F. Clunn, Peter S. Sever, Alun D. Hughes

Journal:

International Journal of Cardiology

Year:

2010

Language:

english

File:

PDF, 310 KB

english, 2010

98

A new automated system to identify a consistent sampling position to make tissue Doppler and transmitral Doppler measurements of E, E′ and E/E′

Niti M. Dhutia, Graham D. Cole, Keith Willson, Daniel Rueckert, Kim H. Parker, Alun D. Hughes, Darrel P. Francis

Journal:

International Journal of Cardiology

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

99

Reply

T. Hugh Jones, Steven M. Hunter, Alun Price, Gianni D. Angelini

Journal:

The Annals of Thoracic Surgery

Year:

1995

Language:

english

File:

PDF, 178 KB

english, 1995

100

Tau haplotype frequency in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Alun Hughes, David Mann, Stuart Pickering-Brown

Journal:

Experimental Neurology

Year:

2003

Language:

english

File:

PDF, 69 KB

english, 2003

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