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51

TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines

William D. Hastings, David E. Anderson, Nasim Kassam, Ken Koguchi, Edward A. Greenfield, Sally C. Kent, Xin Xiao Zheng, Terry B. Strom, David A. Hafler, Vijay K. Kuchroo

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 545 KB

english, 2009

52

Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis

Duojia Cao, Vivianne Malmström, Clare Baecher-Allan, David Hafler, Lars Klareskog, Christina Trollmo

Journal:

European Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 349 KB

english, 2003

53

Clinical neuroimmunology: edited by J.A. Aarli, M.W.H. Behan and P.O. Behan, Blackwell Scientific Publications, 1987. £60.00 (xviii + 531 pages) ISBN O 632 01635 x

David A. Hafler

Journal:

Immunology Today

Year:

1988

Language:

english

File:

PDF, 377 KB

english, 1988

54

MS: a CNS and systematic autoimmune disease

David A. Hafler, Howard L. Weiner

Journal:

Immunology Today

Year:

1989

Language:

english

File:

PDF, 674 KB

english, 1989

55

T-cell recognition of myelin basic protein

Kai W Wucherpfennig, Howard L Weiner, David A Hafler

Journal:

Immunology Today

Year:

1991

Language:

english

File:

PDF, 894 KB

english, 1991

56

TCR usage in human and experimental demyelinating disease

David A. Hafler, Mark G. Saadeh, Vijay K. Kuchroo, Edgar Milford, Lawrence Steinman

Journal:

Immunology Today

Year:

1996

Language:

english

File:

PDF, 517 KB

english, 1996

57

Droplet-based microfluidic platforms for single T cell secretion analysis of IL-10 cytokine

Tania Konry, Margarita Dominguez-Villar, Clare Baecher-Allan, David A. Hafler, Martin.L. Yarmush

Journal:

Biosensors and Bioelectronics

Year:

2011

Language:

english

File:

PDF, 609 KB

english, 2011

58

T helper cell differentiation in multiple sclerosis and autoimmunity

Roland Martin, Nancy H Ruddle, Stephen Reingold, David A Hafler

Journal:

Immunology Today

Year:

1998

Language:

english

File:

PDF, 128 KB

english, 1998

59

Antigen-specific therapy for autoimmune disease

Leonard C Harrison, David A Hafler

Journal:

Current Opinion in Immunology

Year:

2000

Language:

english

File:

PDF, 181 KB

english, 2000

60

Immunotherapy in autoimmune diseases

Ariel Miller, David A. Hafler, Howard L Weiner

Journal:

Current Opinion in Immunology

Year:

1991

Language:

english

File:

PDF, 231 KB

english, 1991

61

Autoimmunity: What is the turning point?: Editorial overview

Richard A Flavell, David A Hafler

Journal:

Current Opinion in Immunology

Year:

1999

Language:

english

File:

PDF, 53 KB

english, 1999

62

The B7–CD28/CTLA-4 costimulatory pathways in autoimmune disease of the central nervous system

David E Anderson, Arlene H Sharpe, David A Hafler

Journal:

Current Opinion in Immunology

Year:

1999

Language:

english

File:

PDF, 90 KB

english, 1999

63

How does the introduction of computers and wall-mounted plasma screens Impact small group tutorials? Preliminary results

B Price Kerfoot, Barbara A Masser, Janet P Hafler

Journal:

Medical Education

Year:

2003

Language:

english

File:

PDF, 123 KB

english, 2003

64

Enhanced B7 Costimulatory Molecule Expression In Inflammatory Human Sural Nerve Biopsies

R Kiefer, F Dangond, M Mueller, KV Toyka, DA Hafler, HP Hartung

Journal:

Journal of the Peripheral Nervous System

Year:

2001

Language:

english

File:

PDF, 71 KB

english, 2001

65

Antigen-specific therapies for the treatment of autoimmune diseases

David A. Hafler, Howard L. Weiner

Journal:

Seminars in Immunopathology

Year:

1995

Language:

english

File:

PDF, 1024 KB

english, 1995

66

Multiple Sclerosis and Regulatory T Cells

Cristina Maria Costantino, Clare Baecher-Allan, David A. Hafler

Journal:

Journal of Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 192 KB

english, 2008

67

Multiple sclerosis

David A. Hafler, Jacqueline M. Slavik, David E. Anderson, Kevin C. O'Connor, Philip De Jager, Clare Baecher-Allan

Journal:

Immunological Reviews

Year:

2005

Language:

english

File:

PDF, 630 KB

english, 2005

68

Human regulatory T cells and their role in autoimmune disease

Clare Baecher-Allan, David A. Hafler

Journal:

Immunological Reviews

Year:

2006

Language:

english

File:

PDF, 268 KB

english, 2006

69

Advancing educators and education by defining the components and evidence associated with educational scholarship

Deborah Simpson, Ruth-Marie E Fincher, Janet P Hafler, David M Irby, Boyd F Richards, Gary C Rosenfeld, Thomas R Viggiano

Journal:

Medical Education

Year:

2007

Language:

english

File:

PDF, 103 KB

english, 2007

70

Designing a surgical ‘resident-as-teacher’ programme

B Price Kerfoot, Kate S Nabha, Janet Palmer Hafler

Journal:

Medical Education

Year:

2004

Language:

english

File:

PDF, 51 KB

english, 2004

71

Influence of new educational technology on problem-based learning at Harvard Medical School

B Price Kerfoot, Barbara A Masser, Janet P Hafler

Journal:

Medical Education

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

72

The impact of duty hour restrictions on teaching by surgical residents

B Price Kerfoot, Kate S Nabha, Janet P Hafler

Journal:

Medical Education

Year:

2005

Language:

english

File:

PDF, 54 KB

english, 2005

73

T Cells in Multiple Sclerosis and Inflammatory Central Nervous System Diseases

David A. Hafler, Howard L. Weiner

Journal:

Immunological Reviews

Year:

1987

Language:

english

File:

PDF, 8.65 MB

english, 1987

74

Autoimmunity risk alleles in costimulation pathways

Lisa M. Maier, David A. Hafler

Journal:

Immunological Reviews

Year:

2009

Language:

english

File:

PDF, 371 KB

english, 2009

75

Oral Administration of Myelin Induces Antigen-specific TGF-β1 Secreting T Cells in Patients with Multiple Sclerosis

DAVID A. HAFLER, SALLY C. KENT, MATTHEW J. PIETRUSEWICZ, SAMIA J. KHOURY, HOWARD L. WEINER, HIKOAKI FUKAURA

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 678 KB

english, 1997

76

Oral Administration of Myelin Induces Antigen-specific TGF-β1-secreting T Cells in Multiple Sclerosis Patients

SALLY C. KENT, HIKOAKI FUKAURA, MATTHEW J. PIETRUSEWICZ, SAMIA J. KHOURY, HOWARD L. WEINER, DAVID A. HAFLER

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 763 KB

english, 1997

77

T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

Ota, Kohei, Matsui, Makoto, Milford, Edgar L., Mackin, Glenn A., Weiner, Howard L., Hafler, David A.

Journal:

Year:

1990

File:

PDF, 601 KB

1990

78

10.1038/72323

Anderson, David E., Bieganowska, Katarzyna D., Bar-Or, Amit, Oliveira, Enedina M.L., Carreno, Beatriz, Collins, Mary, Hafler, David A.

Journal:

Nature Medicine

Year:

2000

Language:

english

File:

PDF, 139 KB

english, 2000

79

Jerky/Earthbound facilitates cell-specific Wnt/Wingless signalling by modulating β-catenin–TCF activity

Benchabane, Hassina, Xin, Nan, Tian, Ai, Hafler, Brian P, Nguyen, Kerrie, Ahmed, Ayah, Ahmed, Yashi

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 3.07 MB

english, 2011

80

CD226 Gly307Ser association with multiple autoimmune diseases

Hafler, J P, Maier, L M, Cooper, J D, Plagnol, V, Hinks, A, Simmonds, M J, Stevens, H E, Walker, N M, Healy, B, Howson, J M M

Journal:

Genes and Immunity

Year:

2008

Language:

english

File:

PDF, 116 KB

english, 2008

81

A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility

Bush, W S, McCauley, J L, DeJager, P L, Dudek, S M, Hafler, D A, Gibson, R A, Matthews, P M, Kappos, L, Naegelin, Y, Polman, C H

Journal:

Genes and Immunity

Year:

2011

Language:

english

File:

PDF, 262 KB

english, 2011

82

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

Kent, Sally C., Chen, Yahua, Bregoli, Lisa, Clemmings, Sue M., Kenyon, Norma Sue, Ricordi, Camillo, Hering, Bernhard J., Hafler, David A.

Journal:

Year:

2005

Language:

english

File:

PDF, 271 KB

english, 2005

83

Immunology: Insulin auto-antigenicity in type 1 diabetes (Reply)

Clemmings, Sue M., Hering, Bernhard, Kenyon, Norma Sue, Ricordi, Camillo, Hafler, David A., Kent, Sally C., Chen, Yahua, Bregoli, Lisa

Journal:

Year:

2005

Language:

english

File:

PDF, 94 KB

english, 2005

84

Protective and therapeutic role for αB-crystallin in autoimmune demyelination

Ousman, Shalina S., Tomooka, Beren H., van Noort, Johannes M., Wawrousek, Eric F., O’Conner, Kevin, Hafler, David A., Sobel, Raymond A., Robinson, William H., Steinman, Lawrence

Journal:

Year:

2007

Language:

english

File:

PDF, 1.02 MB

english, 2007

85

IL-21 and TGF-β are required for differentiation of human TH17 cells

Yang, Li, Anderson, David E., Baecher-Allan, Clare, Hastings, William D., Bettelli, Estelle, Oukka, Mohamed, Kuchroo, Vijay K., Hafler, David A.

Journal:

Year:

2008

Language:

english

File:

PDF, 271 KB

english, 2008

86

The developing mosaic of autoimmune disease risk

Maier, Lisa M, Hafler, David A

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 213 KB

english, 2008

87

Opinion: Applying a new generation of genetic maps to understand human inflammatory disease

Hafler, David A., Jager, Philip L. De

Journal:

Nature Reviews Immunology

Year:

2005

Language:

english

File:

PDF, 208 KB

english, 2005

88

Cytokines and interventional immunology

Hafler, David A.

Journal:

Nature Reviews Immunology

Year:

2007

Language:

english

File:

PDF, 143 KB

english, 2007

89

FOXP3+ regulatory T cells in the human immune system

Sakaguchi, Shimon, Miyara, Makoto, Costantino, Cristina M., Hafler, David A.

Journal:

Nature Reviews Immunology

Year:

2010

Language:

english

File:

PDF, 448 KB

english, 2010

90

Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn's disease and multiple sclerosis

De Jager, Philip L, Sawcer, Stephen, Waliszewska, Alicja, Farwell, Lisa, Wild, Gary, Cohen, Albert, Langelier, Diane, Bitton, Alain, Compston, Alastair, Hafler, David A

Journal:

European Journal of Human Genetics

Year:

2005

Language:

english

File:

PDF, 81 KB

english, 2005

91

The role of inflammatory bowel disease susceptibility loci in multiple sclerosis and systemic lupus erythematosus

De Jager, P L, Graham, R, Farwell, L, Sawcer, S, Richardson, A, Behrens, T W, Compston, A, Hafler, D A, Kere, J, Vyse, T J

Journal:

Genes and Immunity

Year:

2006

Language:

english

File:

PDF, 123 KB

english, 2006

92

Immunologic Mechanisms and Therapy in Multiple Sclerosis

DAVID A. HAFLER, HOWARD L. WEINER

Journal:

Immunological Reviews

Year:

1995

Language:

english

File:

PDF, 10.74 MB

english, 1995

93

Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex

Zuvich, R. L., Bush, W. S., McCauley, J. L., Beecham, A. H., De Jager, P. L., Ivinson, A. J., Compston, A., Hafler, D. A., Hauser, S. L., Sawcer, S. J.

Journal:

Human Molecular Genetics

Year:

2011

Language:

english

File:

PDF, 229 KB

english, 2011

94

Increased Protein Kinase C Activity in Human Memory T Cells

Per Höllsberg, Judy Melinek, Deborah Benjamin, David A. Hafler

Journal:

Cellular Immunology

Year:

1993

File:

PDF, 364 KB

1993

95

Cross-Reactivity of T-Cell Clones Specific for Altered Peptide Ligands of Myelin Basic Protein

Lara J. Ausubel, Katarzyna D. Bieganowska, David A. Hafler

Journal:

Cellular Immunology

Year:

1999

Language:

english

File:

PDF, 115 KB

english, 1999

96

Cross-Reactivity of Borrelia burgdorferi and Myelin Basic Protein-Specific T Cells Is Not Observed in Borrelial Encephalomyelitis

Annette Pohl-Koppe, Eric L. Logigian, Allen C. Steere, David A. Hafler

Journal:

Cellular Immunology

Year:

1999

Language:

english

File:

PDF, 51 KB

english, 1999

97

Cytotoxic γδ T Lymphocytes Associated with an Epstein–Barr Virus-Induced Posttransplantation Lymphoproliferative Disorder

Marc E. Rothenberg, Wim E.J. Weber, Janina A. Longtine, David A. Hafler

Journal:

Clinical Immunology and Immunopathology

Year:

1996

Language:

english

File:

PDF, 606 KB

english, 1996

98

Pulse Cyclophosphamide Plus Methylprednisolone Induces Myelin-Antigen-Specific IL-4-Secreting T Cells in Multiple Sclerosis Patients

Hiroshi Takashima, Derek R. Smith, Hikoaki Fukaura, Samia J. Khoury, David A. Hafler, Howard L. Weiner

Journal:

Clinical Immunology and Immunopathology

Year:

1998

Language:

english

File:

PDF, 118 KB

english, 1998

99

HTLV-I-Infected T Cells Evade the Antiproliferative Action of IFN-β

Derek Smith, Guy J. Buckle, David A. Hafler, David A. Frank, Per Höllsberg

Journal:

Year:

1999

Language:

english

File:

PDF, 117 KB

english, 1999

100

FcR-mediated crosslinking of Ta1 (CDw26) induces human T lymphocyte activation

Nam H. Dang, David A. Hafler, Stuart F. Schlossman, James B. Breitmeyer

Journal:

Cellular Immunology

Year:

1990

Language:

english

File:

PDF, 1.13 MB

english, 1990