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1

Enzymatic Synthesis of Peptides and Ras Lipopeptides Employing Choline Ester as a Solubilizing, Protecting, and Activating Group

Dipl.-Chem. Michael Schelhaas, Dipl.-Chem. Simone Glomsda, Dr. Marion Hänsler, Prof. Hans-Dieter Jakubke, Prof. Herbert Waldmann

Journal:

Angewandte Chemie International Edition

Year:

1996

Language:

english

File:

PDF, 535 KB

english, 1996

2

Peptides: Chemistry and Biology || Peptide Synthesis

Sewald, Norbert, Jakubke, Hans-Dieter

Year:

2009

Language:

english

File:

PDF, 4.25 MB

english, 2009

3

Peptides: Chemistry and Biology || Fundamental Chemical and Structural Principles

Sewald, Norbert, Jakubke, Hans-Dieter

Year:

2009

Language:

english

File:

PDF, 1.61 MB

english, 2009

4

Peptides: Chemistry and Biology || Introduction and Background

Sewald, Norbert, Jakubke, Hans-Dieter

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

5

Peptides: Chemistry and Biology || Synthesis Concepts for Peptides and Proteins

Sewald, Norbert, Jakubke, Hans-Dieter

Year:

2009

Language:

english

File:

PDF, 1.25 MB

english, 2009

6

Peptides: Chemistry and Biology || Biology of Peptides

Sewald, Norbert, Jakubke, Hans-Dieter

Year:

2009

Language:

english

File:

PDF, 2.36 MB

english, 2009

7

Peptides: Chemistry and Biology || Peptide and Protein Design, Pseudopeptides, and Peptidomimetics

Sewald, Norbert, Jakubke, Hans-Dieter

Year:

2009

Language:

english

File:

PDF, 1.75 MB

english, 2009

8

Peptides: Chemistry and Biology || Application of Peptides and Proteins

Sewald, Norbert, Jakubke, Hans-Dieter

Year:

2009

Language:

english

File:

PDF, 1014 KB

english, 2009

9

Peptides: Chemistry and Biology || Combinatorial Peptide Synthesis

Sewald, Norbert, Jakubke, Hans-Dieter

Year:

2009

Language:

english

File:

PDF, 948 KB

english, 2009

10

Peptides: Chemistry and Biology || Peptides in Proteomics

Sewald, Norbert, Jakubke, Hans-Dieter

Year:

2009

Language:

english

File:

PDF, 391 KB

english, 2009

11

Peptides: Chemistry and Biology || Synthesis of Special Peptides and Peptide Conjugates

Sewald, Norbert, Jakubke, Hans-Dieter

Year:

2009

Language:

english

File:

PDF, 2.04 MB

english, 2009

12

Peptides: Chemistry and Biology || Index

Sewald, Norbert, Jakubke, Hans-Dieter

Year:

2009

Language:

english

File:

PDF, 125 KB

english, 2009

13

Nucleophile specificity of subtilisin in an organic solvent with low water content: Investigation via acyl transfer reactions

Václav Čeřovský, Hans-Dieter Jakubke

Journal:

Biotechnology and Bioengineering

Year:

1996

Language:

english

File:

PDF, 581 KB

english, 1996

14

Proteolytically stable peptides by incorporation of α-Tfm amino acids

Beate Koksch, Norbert Sewald, Hans-Jörg Hofmann, Klaus Burger, Hans-Dieter Jakubke

Journal:

Journal of Peptide Science

Year:

1997

Language:

english

File:

PDF, 234 KB

english, 1997

15

Enzymatic Peptide Synthesis in Frozen Aqueous Solution: Use of Nα-unprotected Peptide Esters as Acyl Donors

Sabine Gerisch, Hans-Dieter Jakubke

Journal:

Journal of Peptide Science

Year:

1997

Language:

english

File:

PDF, 84 KB

english, 1997

16

Grundprinzipien der proteasekatalysierten Knüpfung der Peptidbindung

Prof. Dr. Hans-Dieter Jakubke, Dr. Peter Kuhl, Dr. Andreas Könnecke

Journal:

Angewandte Chemie

Year:

1985

Language:

german

File:

PDF, 908 KB

german, 1985

17

Proteasekatalysierte kinetisch kontrollierte Peptidsynthese

Volker Schellenberger, Prof. Dr. Hans-Dieter Jakubke

Journal:

Angewandte Chemie

Year:

1991

Language:

german

File:

PDF, 1.37 MB

german, 1991

18

Peptid-Ligasen – Werkzeuge für die Peptidsynthese

Prof. Dr. Hans-Dieter Jakubke

Journal:

Angewandte Chemie

Year:

1995

Language:

german

File:

PDF, 303 KB

german, 1995

19

Enzymatische Synthese von Peptiden und Ras-Lipopeptiden unter Verwendung des Cholinesters als löslichkeitsvermittelnder Schutz- und Aktivierungsgruppe

Michael Schelhaas, Simone Glomsda, Dr. Marion Hänsler, Prof. Dr. Hans-Dieter Jakubke, Prof. Dr. Herbert Waldmann

Journal:

Angewandte Chemie

Year:

1996

File:

PDF, 523 KB

1996

20

Proteasekatalysierter Peptidaufbau vom N- zum C-Terminus: eine vorteilhafte Strategie

Frank Bordusa, Dr. Dirk Ullmann, Prof. Dr. Hans-Dieter Jakubke

Journal:

Angewandte Chemie

Year:

1997

File:

PDF, 411 KB

1997

21

Substratmimetica-vermittelte Peptidsynthese: eine Strategie zur spezifitätsunabhängigen, irreversiblen Ligation

Frank Bordusa, Dr. Dirk Ullmann, Christian Elsner, Prof. Dr. Hans-Dieter Jakubke

Journal:

Angewandte Chemie

Year:

1997

File:

PDF, 384 KB

1997

22

Basic Principles of Protease-Catalyzed Peptide Bond Formation

Prof. Dr. Hans-Dieter Jakubke, Dr. Peter Kuhl, Dr. Andreas Könnecke

Journal:

Angewandte Chemie International Edition

Year:

1985

Language:

english

File:

PDF, 928 KB

english, 1985

23

Protease-Catalyzed Kinetically Controlled Peptide Synthesis

Dr. Volker Schellenberger, Prof. Dr. Hans-Dieter Jakubke

Journal:

Angewandte Chemie International Edition

Year:

1991

Language:

english

File:

PDF, 1.37 MB

english, 1991

24

Peptide Ligases—Tools for Peptide Synthesis

Prof. Dr. Hans-Dieter Jakubke

Journal:

Angewandte Chemie International Edition

Year:

1995

Language:

english

File:

PDF, 365 KB

english, 1995

25

Protease-Catalyzed Peptide Synthesis from N- to C-Terminus: An Advantageous Strategy

Frank Bordusa, Dr. Dirk Ullmann, Prof. Dr. Hans-Dieter Jakubke

Journal:

Angewandte Chemie International Edition

Year:

1997

Language:

english

File:

PDF, 442 KB

english, 1997

26

Substrate Mimetic Mediated Peptide Synthesis: An Irreversible Ligation Strategy That Is Independent of Substrate Specificity

Frank Bordusa, Dr. Dirk Ullmann, Christian Elsner, Prof. Dr. Hans-Dieter Jakubke

Journal:

Angewandte Chemie International Edition

Year:

1997

Language:

english

File:

PDF, 593 KB

english, 1997

27

Protease-catalyzed peptide synthesis using inverse substrates: The influence of reaction conditions on the trypsin acyl transfer efficiency

Volker Schellenberger, Hans-Dieter Jakubke, Nina P. Zapevalova, Yuri V. Mitin

Journal:

Biotechnology and Bioengineering

Year:

1991

Language:

english

File:

PDF, 499 KB

english, 1991

28

Protease-catalyzed peptide synthesis using inverse substrates: The synthesis of Pro-Xaa-bonds by trypsin

Volker Schellenberger, Ute Schellenberger, Hans-Dieter Jakubke, Nina P. Zapevalova, Yuri V. Mitin

Journal:

Biotechnology and Bioengineering

Year:

1991

Language:

english

File:

PDF, 296 KB

english, 1991

29

How to predict product yield in kinetically controlled enzymatic peptide synthesis

Mikhail Yu. Gololobov, Elena V. Kozlova, Ivan L. Borisov, Ute Schellenberger, Volker Schellenberger, Hans-Dieter Jakubke

Journal:

Biotechnology and Bioengineering

Year:

1992

Language:

english

File:

PDF, 455 KB

english, 1992

30

Synthese von Aminoacyl- und Peptidyl-selenophenolen und deren Verwendung zur Darstellung linearer und cyclischer Peptide

Hans-Dieter Jakubke

Journal:

European Journal of Inorganic Chemistry

Year:

1964

File:

PDF, 661 KB

1964

31

Über aktivierte Ester, VII. Untersuchungen über die peptidchemische Verwendbarkeit von Acylaminosäure-chinolyl-(8)-estern

Hans-Dieter Jakubke, Arno Voigt

Journal:

European Journal of Inorganic Chemistry

Year:

1966

Language:

german

File:

PDF, 623 KB

german, 1966

32

Über aktivierte Ester, VIII. Peptidsynthesen mit halogensubstituierten Acylaminosäure- und Acylpeptid-[chinolyl-(8)-estern]

Hans-Dieter Jakubke, Arno Voigt

Journal:

European Journal of Inorganic Chemistry

Year:

1966

Language:

german

File:

PDF, 581 KB

german, 1966

33

Über aktivierte Ester, IX. Untersuchungen über den Mechanismus der racemisierungsfreien Peptidsynthese mit Acylaminosäure-chinolyl-(8)-estern

Hans-Dieter Jakubke, Arno Voigt†, Siegmar Burkhardt

Journal:

European Journal of Inorganic Chemistry

Year:

1967

Language:

german

File:

PDF, 327 KB

german, 1967

34

ChemInform Abstract: Protease-Catalyzed Peptide Synthesis

Dirk Ullmann, Hans-Dieter Jakubke

Journal:

Year:

2000

File:

PDF, 24 KB

2000

35

Hydrolysis and Formation of Peptides

Hans-Dieter Jakubke

Journal:

Year:

2003

File:

PDF, 49 KB

2003

36

Aminoacyl-Derivate des α-Selenonaphthols und ihre Verwendung zur Peptidsynthese

Hans-Dieter Jakubke

Journal:

European Journal of Organic Chemistry

Year:

1965

Language:

german

File:

PDF, 333 KB

german, 1965

37

An apparatus for continuous analysis of protease-catalyzed acyl transfer reactions

Volker Schellenberger, Ute Schellenberger, Yuri V. Mitin, Hans-Dieter Jakubke

Journal:

Analytical Biochemistry

Year:

1987

Language:

english

File:

PDF, 328 KB

english, 1987

38

Acyl transfer reactions catalyzed by native and modified α-chymotrypsin in acetonitrile with low water content

Václav Čeěovský, Hans-Dieter Jakubke

Journal:

Enzyme and Microbial Technology

Year:

1994

Language:

english

File:

PDF, 607 KB

english, 1994

39

Enzymatic peptide synthesis in frozen aqueous systems: Use of Nα-unprotected unusual acyl donors

Sabine Gerisch, Hans-Dieter Jakubke, Hans-Jörn Kreuzfeld

Journal:

Tetrahedron: Asymmetry

Year:

1995

Language:

english

File:

PDF, 323 KB

english, 1995

40

Synthesis, structure and biological activity of α-trifluoromethyl-substituted thyreotropin releasing hormone

Beate Koksch, Dirk Ullmann, Hans-Dieter Jakubke, Klaus Burger

Journal:

Journal of Fluorine Chemistry

Year:

1996

Language:

english

File:

PDF, 496 KB

english, 1996

41

Direct conversion of porcine insulin into human insulin ester catalyzed by immobilized trypsin

Andreas Könnecke, Christoph Schönfels, Marion Hänsler, Hans-Dieter Jakubke

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 128 KB

english, 1990

42

Chymotrypsin suspended in organic solvents with salt hydrates is a good catalyst for peptide synthesis from mainly undissolved reactants

Peter Kuhl, Peter J. Halling, Hans-Dieter Jakubke

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 202 KB

english, 1990

43

Endoproteinase Pro-C-Catalyzed Peptide Bond Formation in Frozen Aqueous Systems

Marion Haensler, Hans-Dieter Jakubke

Journal:

Enzyme and Microbial Technology

Year:

1998

Language:

english

File:

PDF, 145 KB

english, 1998

44

Single-step synthesis of kyotorphin in frozen solutions by chymotrypsin

Helle Meos, Vello Tõugu, Mati Haga, Aavo Aaviksaar, Matthias Schuster, Hans-Dieter Jakubke

Journal:

Tetrahedron: Asymmetry

Year:

1993

Language:

english

File:

PDF, 266 KB

english, 1993

45

Protease-catalysed synthesis of peptides containing histidine and lysine

Karin Beck-Piotraschke, Hans-Dieter Jakubke

Journal:

Tetrahedron: Asymmetry

Year:

1998

Language:

english

File:

PDF, 266 KB

english, 1998

46

Synthesis of α-fluoroalkyl substituted peptides via enzymatic fragment condensation

Frank Bordusa, Christina Dahl, Hans-Dieter Jakubke, Klaus Burger, Beate Koksch

Journal:

Tetrahedron: Asymmetry

Year:

1999

Language:

english

File:

PDF, 172 KB

english, 1999

47

The application of papain, ficin and clostripain in kinetically controlled peptide synthesis in frozen aqueous solutions

Dr Marion Hänsler, Grit Ullmann, Hans-Dieter Jakubke

Journal:

Journal of Peptide Science

Year:

1995

Language:

english

File:

PDF, 398 KB

english, 1995

48

Nonconventional Protease Catalysis in Frozen Aqueous Solutions

Marion Hänsler, Hans-Dieter Jakubke

Journal:

Journal of Peptide Science

Year:

1996

Language:

english

File:

PDF, 929 KB

english, 1996

49

Synthese von kovalent an polymere Träger gebundenen niedermolekularen Wirkstoffen und Versuche zur enzymatischen Reaktivierung

Hans-Dieter Jakubke, Edmund Busch

Journal:

Zeitschrift für Chemie

Year:

1973

Language:

german

File:

PDF, 291 KB

german, 1973

50

Über die Darstellung von S-Carboxymethyl-L-Homocysteinamid

Klaus Neubert, Bianka Hartrodt, Edith Berger, Hans-Werner Mansfeld, Hans-Dieter Jakubke

Journal:

Zeitschrift für Chemie

Year:

1978

Language:

german

File:

PDF, 277 KB

german, 1978

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