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51

Investigation of the mechanisms underlying the hypophagic effects of the 5-HT and noradrenaline reuptake inhibitor, sibutramine, in the rat

Helen C. Jackson, M. Clair Bearham, Lisa J. Hutchins, Sarah E. Mazurkiewicz, Andrew M. Needham, David J. Heal

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 353 KB

english, 1997

52

Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat

Helen C. Jackson, Andrew M. Needham, Lisa J. Hutchins, Sarah E. Mazurkiewicz, David J. Heal

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 334 KB

english, 1997

53

Thermogenic effects of sibutramine and its metabolites

Ian P Connoley, Yong-Ling Liu, Ian Frost, Ian P Reckless, David J Heal, Michael J Stock

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 231 KB

english, 1999

54

Sibutramine reduces feeding, body fat and improves insulin resistance in dietary-obese male Wistar rats independently of hypothalamic neuropeptide Y

Michael Brown, Chen Bing, Peter King, Lucy Pickavance, David Heal, John Wilding

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 190 KB

english, 2001

55

Differences in the mechanisms that increase noradrenaline efflux after administration of d-amphetamine: a dual-probe microdialysis study in rat frontal cortex and hypothalamus

Sandrine M Géranton, David J Heal, S Clare Stanford

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 173 KB

english, 2003

56

Chronic 5-HT6 receptor modulation by E-6837 induces hypophagia and sustained weight loss in diet-induced obese rats

Angels Fisas, Xavier Codony, Gonzalo Romero, Alberto Dordal, Jesus Giraldo, Ramon Mercé, Jörg Holenz, David Heal, Helmut Buschmann, Petrus Johan Pauwels

Journal:

British Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 334 KB

english, 2006

57

Public awareness, knowledge and attitudes regarding the CEN system in South Australia

Penny Heale, David Hawks, Simon Lenton

Journal:

Drug and Alcohol Review

Year:

2000

Language:

english

File:

PDF, 147 KB

english, 2000

58

Comparison of the effects of bupropion and nicotine on locomotor activation and dopamine release in vivo

Nimish Sidhpura, Peter Redfern, Helen Rowley, David Heal, Susan Wonnacott

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 434 KB

english, 2007

59

Distinct pharmacological profiles for nicotinic AChR-evoked noradrenaline release in rat frontal cortex and hippocampus

Alexandra Kennett, David Heal, Susan Wonnacott

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 76 KB

english, 2009

60

Pharmacological characterisation of the thermogenic effect of bupropion

Yong-Ling Liu, Ian P. Connoley, David J. Heal, Michael J. Stock

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 343 KB

english, 2004

61

GABA-evoked depolarisations in the rat cortical wedge: involvement of GABAA receptors and HCO3− ions

Ian Phillips, Keith F Martin, Kevin S.J Thompson, David J Heal

Journal:

Year:

1998

Language:

english

File:

PDF, 98 KB

english, 1998

62

Effects on serotonin in rat hypothalamus of d-fenfluramine, aminorex, phentermine and fluoxetine

Rui Tao, Anne Fray, Sue Aspley, Richard Brammer, David Heal, Sidney Auerbach

Journal:

European Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 314 KB

english, 2002

63

Comparison of the thermogenic and hypophagic effects of sibutramine's metabolite 2 and other monoamine reuptake inhibitors

Yong-Ling Liu, Ian P Connoley, Jonathan Harrison, David J Heal, Michael J Stock

Journal:

European Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 226 KB

english, 2002

64

Repeated electroconvulsive shock attenuates clonidine-induced hypoactivity in rodents

David J. Heal, Hiroko Akagi, Julie M. Bowdler, A.Richard Green

Journal:

European Journal of Pharmacology

Year:

1981

Language:

english

File:

PDF, 557 KB

english, 1981

65

Hypophysectomy alters both 5-hydroxytryptamine- and α2-adrenoceptor-mediated behavioural changes in the rat

David J. Heal, Kevin M. O'Shaughnessy, Sharon L. Smith, David J. Nutt

Journal:

European Journal of Pharmacology

Year:

1983

Language:

english

File:

PDF, 353 KB

english, 1983

66

DSP-4 lesioning prevents the enhancement of dopamine and 5-hydroxytryptamine mediated behavioural changes by repeated electroconvulsive shock

David J. Heal, Cledwyn L. Davies, Guy M. Goodwin

Journal:

European Journal of Pharmacology

Year:

1985

Language:

english

File:

PDF, 376 KB

english, 1985

67

In mice repeated administration of electroconvulsive shock or desmethylimipramine produces rapid alterations in 5-HT2-mediated head-twitch responses and cortical 5-HT2 receptor number

Alan Metz, David J. Heal

Journal:

European Journal of Pharmacology

Year:

1986

Language:

english

File:

PDF, 311 KB

english, 1986

68

Repeated electroconvulsive shock prevents increased neocortical β1-adrenoceptor binding after DSP-4 treatment in rats

David J. Dooley, David J. Heal, Guy M. Goodwin

Journal:

European Journal of Pharmacology

Year:

1987

Language:

english

File:

PDF, 392 KB

english, 1987

69

Clonidine produces mydriasis in conscious mice by activating central α2-adrenoceptors

David J. Heal, Michael R. Prow, W. Roger Buckett

Journal:

European Journal of Pharmacology

Year:

1989

Language:

english

File:

PDF, 585 KB

english, 1989

70

Clonidine-induced hypoactivity and mydriasis in mice are respectively mediated via pre- and postsynaptic α2-adrenoceptors in the brain

David J. Heal, Michael R. Prow, W. Roger Buckett

Journal:

European Journal of Pharmacology

Year:

1989

Language:

english

File:

PDF, 809 KB

english, 1989

71

Quantification of presynaptic α2-adrenoceptors in rat brain after short-term DSP-4 lesioning

David J. Heal, Sarah A. Butler, Michael R. Prow, W. Roger Buckett

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 457 KB

english, 1993

72

Receptor binding and functional evidence suggest that postsynaptic α2-adrenoceptors in rat brain are of the α2D subtype

David J. Heal, Sharon C. Cheetham, Sarah A. Butler, Jane Gosden, Michael R. Prow, W.Roger Buckett

Journal:

European Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 672 KB

english, 1995

73

Mitigation of methane emissions from constructed farm wetlands

Sunitha R. Pangala, David S. Reay, Kate V. Heal

Journal:

Year:

2010

Language:

english

File:

PDF, 478 KB

english, 2010

74

The impact of turtle excluder devices and bycatch reduction devices on diverse tropical marine communities in Australia's northern prawn trawl fishery

David Brewer, Don Heales, David Milton, Quinton Dell, Gary Fry, Bill Venables, Peter Jones

Journal:

Fisheries Research

Year:

2006

Language:

english

File:

PDF, 427 KB

english, 2006

75

5-HT has contrasting effects in the frontal cortex, but not the hypothalamus, on changes in noradrenaline efflux induced by the monoamine releasing-agent, d-amphetamine, and the reuptake inhibitor, BTS 54 354

Sandrine M. Géranton, David J. Heal, S.Clare Stanford

Journal:

Neuropharmacology

Year:

2004

Language:

english

File:

PDF, 185 KB

english, 2004

76

What is the prognosis for new centrally-acting anti-obesity drugs?

David J. Heal, Jane Gosden, Sharon L. Smith

Journal:

Neuropharmacology

Year:

2012

Language:

english

File:

PDF, 850 KB

english, 2012

77

Genetic diversity and interdependent crop choices in agriculture

Geoffrey Heal, Brian Walker, Simon Levin, Kenneth Arrow, Partha Dasgupta, Gretchen Daily, Paul Ehrlich, Karl-Goran Maler, Nils Kautsky, Jane Lubchenco, Steve Schneider, David Starrett

Journal:

Resource and Energy Economics

Year:

2004

Language:

english

File:

PDF, 85 KB

english, 2004

78

8-OH-DPAT-induced mydriasis in mice: A pharmacological characterisation

Michael R. Prow, Keith F. Martin, David J. Heal

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 752 KB

english, 1996

79

Hemin and related porphyrins inhibit β-amyloid aggregation

David Howlett, Paul Cutler, Simon Heales, Patrick Camilleri

Journal:

Year:

1997

Language:

english

File:

PDF, 460 KB

english, 1997

80

Effect of treatment with glycine and l-carnitine in medium-chain acyl-coenzyme A dehydrogenase deficiency

Piero Rinaldo, Eberhard Schmidt-Sommerfeld, Anthony P. Posca, Simon J.R. Heales, David A. Woolf, James V. Leonard

Journal:

The Journal of Pediatrics

Year:

1993

Language:

english

File:

PDF, 448 KB

english, 1993

81

Elevation of extracellular cortical noradrenaline may contribute to the antidepressant activity of zotepine: an in vivo microdialysis study in freely moving rats

Helen L. Rowley, Ian C. Kilpatrick, Patricia L. Needham, David J. Heal

Journal:

Neuropharmacology

Year:

1998

Language:

english

File:

PDF, 150 KB

english, 1998

82

Determination of body composition in conscious adult female Wistar utilising total body electrical conductivity

Keith, Tracey J. North, Gary Telford, Susan Smith, Richard Brammer, Robert B. Jones, David J. Heal

Journal:

Physiology & Behavior

Year:

2001

Language:

english

File:

PDF, 152 KB

english, 2001

83

Noradrenaline clearance differs in the frontal cortex and hypothalamus: a dual-probe microdialysis study in freely-moving rats

Sandrine M. Géranton, David J. Heal, S.Clare Stanford

Journal:

Neuroscience Letters

Year:

2003

Language:

english

File:

PDF, 86 KB

english, 2003

84

Mutations in the Gene Encoding 3-Hydroxyisobutyryl-CoA Hydrolase Results in Progressive Infantile Neurodegeneration

Ference J. Loupatty, Peter T. Clayton, Jos P.N. Ruiter, Rob Ofman, Lodewijk IJlst, Garry K. Brown, David R. Thorburn, Robert A. Harris, Marinus Duran, Carlos DeSousa, Steve Krywawych, Simon J.R. Heale

Journal:

The American Journal of Human Genetics

Year:

2007

Language:

english

File:

PDF, 2.01 MB

english, 2007

85

Effect of chronic treatment with 5-HT1 agonist (8-OH-DPAT and RU 24969) and antagonist (isapirone) drugs on the behavioural responses of mice to 5-HT1 and 5-HT2 agonists

Rosemarie J. De Souza, Guy M. Goodwin, A. Richard Green, David J. Heal

Journal:

British Journal of Pharmacology

Year:

1986

Language:

english

File:

PDF, 1.06 MB

english, 1986

86

The effects of single and repeated electroconvulsive shock administration on the release of 5-hydroxytryptamine and noradrenaline from cortical slices of rat brain

A. Richard Green, David J. Heal, Nigel D. Vincent

Journal:

British Journal of Pharmacology

Year:

1987

Language:

english

File:

PDF, 765 KB

english, 1987

87

Hypothermia induced by baclofen, a possible index of GABAB receptor function in mice, is enhanced by antidepressant drugs and ECS

Julian A. Gray, Guy M. Goodwin, David J. Heal, A. Richard Green

Journal:

British Journal of Pharmacology

Year:

1987

Language:

english

File:

PDF, 1.13 MB

english, 1987

88

Opposing roles for 5-HT1B and 5-HT3 receptors in the control of 5-HT release in rat hippocampus in vivo

Keith F. Martin, Serina Hannon, Ian Phillips, David J. Heal

Journal:

British Journal of Pharmacology

Year:

1992

Language:

english

File:

PDF, 720 KB

english, 1992

89

Characterization of 8-OH-DPAT-induced hypothermia in mice as a 5-HT1A autoreceptor response and its evaluation as a model to selectively identify antidepressants

Keith F. Martin, Ian Phillips, Mitchell Hearson, Michael R. Prow, David J. Heal

Journal:

British Journal of Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.25 MB

english, 1992

90

Mediation of the antidepressant-like effect of 8-OH-DPAT in mice by postsynaptic 5-HT1A receptors

Graham P. Luscombe, Keith F. Martin, Lisa J. Hutchins, Jane Gosden, David J. Heal

Journal:

British Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 1.73 MB

english, 1993

91

Novel targets for the treatment of obesity: a review of progress

Sharon C. Cheetham, Helen C. Jackson, Steven P. Vickers, Keith Dickinson, Robert B. Jones, David J. Heal

Journal:

Drug Discovery Today: Therapeutic Strategies

Year:

2004

Language:

english

File:

PDF, 261 KB

english, 2004

92

Assessment of ropinirole as a reinforcer in rhesus monkeys

Kevin B. Freeman, David J. Heal, Andrew C. McCreary, William L. Woolverton

Journal:

Drug and Alcohol Dependence

Year:

2012

Language:

english

File:

PDF, 463 KB

english, 2012

93

Weak blockade of AMPA receptor-mediated depolarisations in the rat cortical wedge by phenytoin but not lamotrigine or carbamazepine

Ian Phillips, Keith F Martin, Kevin S.J Thompson, David J Heal

Journal:

European Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 121 KB

english, 1997

94

Wed-P43 - Zoteplne enhances noradrenaline levels in rat frontal cortex microdlalysates: Further support for antidepressant activity

Ian C. Kilpatrick, Helen L. Rowley, Patricia L. Needham, David J. Heal

Journal:

European Psychiatry

Year:

1998

Language:

english

File:

PDF, 129 KB

english, 1998

95

TRH-Catecholamine Interactions in Brain and Spinal Cord

GEOFFREY W. BENNETT, CHARLES A. MARSDEN, KEVIN C. F. FONE, JANEL V. JOHNSON, DAVID J. HEAL

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 853 KB

english, 1989

96

The effect of refurbishing a UK steel plant on PM10metal composition and ability to induce inflammation

Gary R Hutchison, David M Brown, Leon R Hibbs, Mathew R Heal, Ken Donaldson, Robert L Maynard, Michelle Monaghan, Andy Nicholl, Vicki Stone

Journal:

Respiratory Research

Year:

2005

Language:

english

File:

PDF, 1.65 MB

english, 2005

97

Validating ecological risk assessments for fisheries: assessing the impacts of turtle excluder devices on elasmobranch bycatch populations in an Australian trawl fishery

Griffiths, Shane P., Brewer, David T., Heales, Don S., Milton, David A., Stobutzki, Ilona C.

Journal:

Marine and Freshwater Research

Year:

2006

Language:

english

File:

PDF, 146 KB

english, 2006

98

DNA profiles of the eastern Canadian wolf and the red wolf provide evidence for a common evolutionary history independent of the gray wolf

Wilson, Paul J, Grewal, Sonya, Lawford, Ian D, Heal, Jennifer NM, Granacki, Angela G, Pennock, David, Theberge, John B, Theberge, Mary T, Voigt, Dennis R, Waddell, Will, Chambers, Robert E, Paquet, Pa

Journal:

Canadian Journal of Zoology

Year:

2000

File:

PDF, 357 KB

2000

99

[International Review of Neurobiology] International Review of Neurobiology Volume 96 Volume 96 || The 5-HT6 Receptor as a Target for Developing Novel Antiobesity Drugs

Year:

2011

Language:

english

File:

PDF, 2.77 MB

english, 2011

100

Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach

Wright, Megan H., Clough, Barbara, Rackham, Mark D., Rangachari, Kaveri, Brannigan, James A., Grainger, Munira, Moss, David K., Bottrill, Andrew R., Heal, William P., Broncel, Malgorzata, Serwa, Remig

Journal:

Nature Chemistry

Year:

2013

Language:

english

File:

PDF, 3.09 MB

english, 2013

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