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51

Trypanothione reductase from Trypanosoma cruzi : Purification and characterization of the crystalline enzyme

R. Luise KRAUTH-SIEGEL, Burkhard ENDERS, Graeme B. HENDERSON, Alan H. FAIRLAMB, R. Heiner SCHIRMER

Journal:

Year:

1987

Language:

english

File:

PDF, 673 KB

english, 1987

52

Inhibition of human glutathione reductase by the nitrosourea drugs 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea : A crystallographic analysis

P. Andrew KARPLUS, R. Luise KRAUTH-SIEGEL, R. Heiner SCHIRMER, Georg E. SCHULZ

Journal:

Year:

1988

Language:

english

File:

PDF, 592 KB

english, 1988

53

Trypanothione reductase from Trypanosoma cruzi : Catalytic properties of the enzyme and inhibition studies with trypanocidal compounds

Maria C. JOCKERS-SCHERÜBL, R. Heiner SCHIRMER, R. Luise KRAUTH-SIEGEL

Journal:

Year:

1989

Language:

english

File:

PDF, 583 KB

english, 1989

54

Cloning and sequencing of mammalian glutathione reductase cDNA

Mevlida TUTIC, Xiang LU, R. Heiner SCHIRMER, Dieter WERNER

Journal:

Year:

1990

Language:

english

File:

PDF, 735 KB

english, 1990

55

Inhibition of Human Glutathione Reductase by S-nitrosoglutathione

Katja Becker, Ming Gui, R. Heiner Schirmer

Journal:

Year:

1995

Language:

english

File:

PDF, 829 KB

english, 1995

56

Glutathione Reductase and Glutamate Dehydrogenase of Plasmodium Falciparum, The Causative Agent of Tropical Malaria

R. Luise Krauth-Siegel, Joachim G. Müller, Friedrich Lottspeich, R. Heiner Schirmer

Journal:

Year:

1996

Language:

english

File:

PDF, 1.01 MB

english, 1996

57

Molecular Cloning and Characterization of a Putative Glutathione Reductase Gene, the PfGR2 Gene, from Plasmodium falciparum

Petra M. Färber, Katja Becker, Sylke Müller, R. Heiner Schirmer, Richard M. Franklin

Journal:

Year:

1996

Language:

english

File:

PDF, 812 KB

english, 1996

58

Denaturation and Reactivation of Dimeric Human Glutathione Reductase : An Assay for Folding Inhibitors

Axel Nordhoff, Christos Tziatzios, Jacomina A. Van Den Broek, Markus K. Schott, Hans-Robert Kalbitzer, Katja Becker, Dieter Schubert, R. Heiner Schirmer

Journal:

Year:

1997

Language:

english

File:

PDF, 1.12 MB

english, 1997

59

Sensitivity of adenylate kinase isozymes from normal and dystrophic human muscle to sulfhydryl reagents

R. Heiner Schirmer, Eva Thuma

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1972

Language:

english

File:

PDF, 338 KB

english, 1972

60

Preparation and characterization of a crystalline human ATP:AMP phosphotransferase

Eva Thuma, R. Heiner Schirmer, Ilse Schirmer

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1972

Language:

english

File:

PDF, 743 KB

english, 1972

61

Glutathione reductase-deficient erythrocytes as host cells of malarial parasites

Zhang Ya, Irene König, R.Heiner Schirmer

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 492 KB

english, 1988

62

Glutathione reductase inhibitors as potential antimalarial drugs: Effects of nitrosoureas on plasmodium falciparum in vitro

Zhang Ya, Ernst Hempelmann, R.Heiner Schirmer

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 572 KB

english, 1988

63

No evidence for inhibition of human glutathione reductase by valproic acid

Axel Nordhoff, R.Heiner Schirmer, Ertan Mayatepek, Katja Becker

Journal:

Biochemical Pharmacology

Year:

1994

Language:

english

File:

PDF, 421 KB

english, 1994

64

The C-terminal fragment of human glutathione reductase contains the postulated catalytic histidine

Renate Untucht-Grau, Georg E. Schulz, R. Heiner Schirmer

Journal:

Year:

1979

Language:

english

File:

PDF, 441 KB

english, 1979

65

On the geometry of leukocyte NADPH-oxidase, a membrane flavoenzyme: Inferences from the structure of glutathione reductase

R.Heiner Schirmer, Georg E. Schulz, Renate Untucht-Grau

Journal:

Year:

1983

Language:

english

File:

PDF, 365 KB

english, 1983

66

The conserved histidine 106 of large thioredoxin reductases is likely to have a structural role but not a base catalyst function

Judit Jacob, R. Heiner Schirmer, Stephan Gromer

Journal:

Year:

2005

Language:

english

File:

PDF, 254 KB

english, 2005

67

Comparative Structural Analysis of Oxidized and Reduced Thioredoxin from Drosophila melanogaster

Markus C. Wahl, Angelika Irmler, Beate Hecker, R. Heiner Schirmer, Katja Becker

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 739 KB

english, 2005

68

Glyoxalase I of the malarial parasite Plasmodium falciparum: evidence for subunit fusion

Rimma Iozef, Stefan Rahlfs, Tammy Chang, Heiner Schirmer, Katja Becker

Journal:

Year:

2003

Language:

english

File:

PDF, 981 KB

english, 2003

69

The 58 kDa mouse selenoprotein is a BCNU-sensitive thioredoxin reductase

Stephan Gromer, R.Heiner Schirmer, Katja Becker

Journal:

Year:

1997

Language:

english

File:

PDF, 577 KB

english, 1997

70

Microinjected glutathione reductase crystals as indicators of the redox status in living cells

Michael A. Keese, Rainer Saffrich, Thomas Dandekar, Katja Becker, R.Heiner Schirmer

Journal:

Year:

1999

Language:

english

File:

PDF, 413 KB

english, 1999

71

Artemisinin resistance on the Thai–Cambodian border

Olaf Müller, Ali Sié, Peter Meissner, R Heiner Schirmer, Bocar Kouyaté

Journal:

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

72

Assembly and functional expression of murine glutathione reductase cDNA: a sequence missing in expressed sequence tag libraries

Rimma Iozef, Katja Becker, Catharina C. Boehme, R.Heiner Schirmer, Dieter Werner

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2000

Language:

english

File:

PDF, 230 KB

english, 2000

73

Antioxidant Status and Nitric Oxide in the Malnutrition Syndrome Kwashiorkor

Fechner, Anke, Böhme, Catharina C, Gromer, Stephan, Funk, Matthias, Schirmer, R Heiner, Becker, Katja

Journal:

Pediatric Research

Year:

2001

Language:

english

File:

PDF, 43 KB

english, 2001

74

Methylene blue as an antimalarial agent

Schirmer, R. Heiner, Coulibaly, Boubacar, Stich, August, Scheiwein, Michael, Merkle, Heiko, Eubel, Jana, Becker, Katja, Becher, Heiko, Müller, Olaf, Zich, Thomas, Schiek, Wolfgang, Kouyaté, Bocar

Journal:

Year:

2003

Language:

english

File:

PDF, 100 KB

english, 2003

75

Subcellular localization of adenylate kinases in Plasmodium falciparum

Jipeng Ma, Stefan Rahlfs, Esther Jortzik, R. Heiner Schirmer, Jude M. Przyborski, Katja Becker

Journal:

Year:

2012

Language:

english

File:

PDF, 1.24 MB

english, 2012

76

Dinitrosyl-Dithiol-Iron Complexes, Nitric Oxide (NO) Carriers In Vivo, as Potent Inhibitors of Human Glutathione Reductase and Glutathione-S-Transferase

Michael A Keese, Matthias Böse, Alexander Mülsch, R.Heiner Schirmer, Katja Becker

Journal:

Biochemical Pharmacology

Year:

1997

Language:

english

File:

PDF, 669 KB

english, 1997

77

Insight into the Selenoproteome of the Malaria Parasite Plasmodium falciparum

Röseler, Anne, Prieto, Judith Helena, Iozef, Rimma, Hecker, Beate, Schirmer, Rolf Heiner, Külzer, Simone, Przyborski, Jude, Rahlfs, Stefan, Becker, Katja

Journal:

Antioxidants & Redox Signaling

Year:

2012

Language:

english

File:

PDF, 315 KB

english, 2012

78

Folding of the four domains and dimerization are impaired by the Gly446.fwdarw.Glu exchange in human glutathione reductase. Implications for the design of antiparasitic drugs

Nordhoff, Axel, Buecheler, Uwe S., Werner, Dieter, Schirmer, R. Heiner

Journal:

Year:

1993

Language:

english

File:

PDF, 2.41 MB

english, 1993

79

Random silent mutagenesis in the initial triplets of the coding region: a technique for adapting human glutathione reductase-encoding cDNA to expression in Escherichia coli

BÃ¼cheler, Uwe S., Werner, Dieter, Heiner Schirmer, R.

Journal:

Year:

1990

Language:

english

File:

PDF, 751 KB

english, 1990

80

Muscle adenylate kinase in Duchenne muscular dystrophy

Fröhlich, Thomas, Reitter, Bernd, Scheffner, Dieter, Heiner Schirmer, R., Untucht-Grau, Renate

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1986

Language:

english

File:

PDF, 65 KB

english, 1986

81

The Mechanism of Thioredoxin Reductase from Human Placenta is Similar to the Mechanisms of Lipoamide Dehydrogenase and Glutathione Reductase and is Distinct from the Mechanism of Thioredoxin Reductase from Escherichia coil

L. David Arscott, Stephan Gromer, R. Heiner Schirmer, Katja Becker and Charles H. Williams

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.46 MB

english, 1997

82

Inhibition of Human Glutathione Reductase by 10-Arylisoalloxazines: Crystallographic, Kinetic, and Electrochemical Studies

Schönleben-Janas, Annette, Kirsch, Peer, Mittl, Peer R. E., Schirmer, R. Heiner, Krauth-Siegel, R. Luise

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 201 KB

english, 1996

83

Mechanism-Based Inactivation of Thioredoxin Reductase from Plasmodium falciparum by Mannich Bases. Implication for Cytotoxicity †

Davioud-Charvet, Elisabeth, McLeish, Michael J., Veine, Donna M., Giegel, David, Arscott, L. David, Andricopulo, Adriano D., Becker, Katja, Müller, Sylke, Schirmer, R. Heiner, Williams,, Charles H., K

Journal:

Year:

2003

Language:

english

File:

PDF, 406 KB

english, 2003

84

Human Thioredoxin Reductase Is Efficiently Inhibited by (2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes. Possible Implications for a Novel Antitumor Strategy

Becker, Katja, Herold-Mende, Christel, Park, Jenny J., Lowe, Gordon, Schirmer, R. Heiner

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 91 KB

english, 2001

85

Role of Active Site Tyrosine Residues in Catalysis by Human Glutathione Reductase †

Krauth-Siegel, R. Luise, Arscott, L. David, Schönleben-Janas, Annette, Schirmer, R. Heiner, Williams, Charles H.

Journal:

Year:

1998

Language:

english

File:

PDF, 325 KB

english, 1998

86

Antimalarial Activity of the Ethanol/Alcohol Oxidase System IN VITRO

Becker, Katja, Hopkins, Thomas R., Schirmer, R. Heiner

Journal:

Free Radical Research

Year:

1990

Language:

english

File:

PDF, 372 KB

english, 1990

87

Redoxprozesse bei Malaria und Trypanosomiasis als Ansatzpunkte für die Chemotherapie

Krauth-Siegel, R. Luise, Schirmer, R. Heiner

Journal:

Nachrichten aus Chemie Technik und Laboratorium

Year:

2010

Language:

german

File:

PDF, 1.42 MB

german, 2010

88

Characterization of the glyoxalases of the malarial parasite Plasmodium falciparum and comparison with their human counterparts

Akoachere, Monique, Iozef, Rimma, Rahlfs, Stefan, Deponte, Marcel, Mannervik, Bengt, Creighton, Donald J., Schirmer, Heiner, Becker, Katja

Journal:

Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 715 KB

english, 2005

89

CA/C1 peptidases of the malaria parasites Plasmodium falciparum and P. berghei and their mammalian hosts – a bioinformatical analysis

Xiao, Ke, Jehle, Franz, Peters, Christoph, Reinheckel, Thomas, Schirmer, R. Heiner, Dandekar, Thomas

Journal:

Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 511 KB

english, 2009

90

Plasmodium falciparum thioredoxins and glutaredoxins as central players in redox metabolism

Rahlfs, Stefan, Nickel, Christine, Deponte, Marcel, Schirmer, R. Heiner, Becker, Katja

Journal:

Year:

2003

File:

PDF, 758 KB

2003

91

Generating compatible translation initiation regions for heterologous gene expression in Escherichia coli by exhaustive periShine-Dalgarno mutagenesis. Human glutathione reductase cDNA as a model

Bücheler, Uwe S., Werner, Dieter, Schirmer, R.Heiner

Journal:

Nucleic Acids Research

Year:

1992

Language:

english

File:

PDF, 943 KB

english, 1992

92

Kontrolle tropischer Infektionskrankheiten - Multidisziplinäre Forschungsprojekte in Burkina Faso

Müller, Olaf, Schirmer, Heiner

Journal:

Flugmedizin · Tropenmedizin · Reisemedizin - FTR

Year:

2007

Language:

german

File:

PDF, 483 KB

german, 2007

93

Molecular basis of glutathione reductase deficiency in human blood cells

Kamerbeek, N. M., van Zwieten, R., de Boer, M., Morren, G., Vuil, H., Bannink, N., Lincke, C., Dolman, K. M., Becker, K., Heiner Schirmer, R., Gromer, S., Roos, D.

Journal:

Year:

2007

Language:

english

File:

PDF, 308 KB

english, 2007

94

A hypothesis on the catalytic mechanism of the selenoenzyme thioredoxin reductase

GROMER, Stephan, WISSING, Josef, BEHNE, Dietrich, ASHMAN, Keith, SCHIRMER, R. Heiner, FLOH, Leopold, BECKER, Katja

Journal:

Biochemical Journal

Year:

1998

Language:

english

File:

PDF, 198 KB

english, 1998

95

The Structure of Porcine Muscle Adenylate Kinase

SCHIRMER, R. HEINER, SCHULZ, GEORG E.

Journal:

Biochemical Society Transactions

Year:

1974

Language:

english

File:

PDF, 82 KB

english, 1974

96

NADPH-dependent disulphide reductases

KRAUTH-SIEGEL, R. LUISE, JOCKERS-SCHERÜBL, MARIA C., BECKER, KATJA, SCHIRMER, R. HEINER

Journal:

Biochemical Society Transactions

Year:

1989

Language:

english

File:

PDF, 369 KB

english, 1989

97

Photoinactivation of glutathione reductase by hematoporphyrin and AI-phtalocyanine tetrasulfonate

Kliukiené, Regina, Maroziené, Audronè, Čénas, Narimantas, Schirmer, R. Heiner

Journal:

Biochemical Society Transactions

Year:

1996

Language:

english

File:

PDF, 108 KB

english, 1996

98

Safety and Efficacy of Methylene Blue Combined with Artesunate or Amodiaquine for Uncomplicated Falciparum Malaria: A Randomized Controlled Trial from Burkina Faso

Zoungrana, Augustin, Coulibaly, Boubacar, Sié, Ali, Walter-Sack, Ingeborg, Mockenhaupt, Frank P., Kouyaté, Bocar, Schirmer, R. Heiner, Klose, Christina, Mansmann, Ulrich, Meissner, Peter, Müller, Olaf

Journal:

Year:

2008

Language:

english

File:

PDF, 162 KB

english, 2008

99

Strong Gametocytocidal Effect of Methylene Blue-Based Combination Therapy against Falciparum Malaria: A Randomised Controlled Trial

Coulibaly, Boubacar, Zoungrana, Augustin, Mockenhaupt, Frank P., Schirmer, R. Heiner, Klose, Christina, Mansmann, Ulrich, Meissner, Peter E., Müller, Olaf, Gregson, Aric

Journal:

Year:

2009

Language:

english

File:

PDF, 186 KB

english, 2009

100

Inherited Glutathione Reductase Deficiency and Plasmodium falciparum Malaria—A Case Study

Gallo, Valentina, Schwarzer, Evelin, Rahlfs, Stefan, Schirmer, R. Heiner, van Zwieten, Rob, Roos, Dirk, Arese, Paolo, Becker, Katja, Carlow, Clotilde K. S.

Journal:

Year:

2009

Language:

english

File:

PDF, 237 KB

english, 2009