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51

Prolonged survival with improved tolerability in higher-risk myelodysplastic syndromes: azacitidine compared with low dose ara-C

Pierre Fenaux, Norbert Gattermann, John F. Seymour, Eva Hellström-Lindberg, Ghulam J. Mufti, Ulrich Duehrsen, Steven D. Gore, Fernando Ramos, Odile Beyne-Rauzy, Alan List, David McKenzie, Jay Backstro

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 155 KB

english, 2010

52

Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome

Andrea Pellagatti, Mario Cazzola, Aristoteles Giagounidis, Janet Perry, Luca Malcovati, Matteo G. Della Porta, Martin Jädersten, Sally Killick, Paresh Vyas, Eva Hellström-Lindberg, James S. Wainscoat,

Journal:

British Journal of Haematology

Year:

2011

Language:

english

File:

PDF, 77 KB

english, 2011

53

Myelodysplastic syndromes: biology and treatment

M. Jädersten, E. Hellström-Lindberg

Journal:

Journal of Internal Medicine

Year:

2009

Language:

english

File:

PDF, 368 KB

english, 2009

54

Reduced DNAM-1 expression on bone marrow NK cells associated with impaired killing of CD34+ blasts in myelodysplastic syndrome

Carlsten, M, Baumann, B C, Simonsson, M, Jädersten, M, Forsblom, A-M, Hammarstedt, C, Bryceson, Y T, Ljunggren, H-G, Hellström-Lindberg, E, Malmberg, K-J

Journal:

Year:

2010

Language:

english

File:

PDF, 733 KB

english, 2010

55

The effect of modulation of glutathione cellular content on busulphan-induced cytotoxicity on hematopoietic cells in vitro and in vivo

Hassan, Z, Hellström-Lindberg, E, Alsadi, S, Edgren, M, Hägglund, H, Hassan, M

Journal:

Bone Marrow Transplantation

Year:

2002

Language:

english

File:

PDF, 134 KB

english, 2002

56

Stem cell transplantation from identical twins in patients with myelodysplastic syndromes

Kröger, N, Brand, R, van Biezen, A, Bron, D, Blaise, D, Hellström-Lindberg, E, Gahrton, G, Powles, R, Littlewood, T, Chapuis, B

Journal:

Bone Marrow Transplantation

Year:

2004

Language:

english

File:

PDF, 156 KB

english, 2004

57

Early mitochondrial alterations in ATRA-induced cell death

Schmidt-Mende, J, Gogvadze, V, Hellström-Lindberg, E, Zhivotovsky, B

Journal:

Cell Death & Differentiation

Year:

2005

Language:

english

File:

PDF, 321 KB

english, 2005

58

Cleavage of Bcl-2 is an early event in chemotherapy-induced apoptosis of human myeloid leukemia cells

Fadeel, B, Hassan, Z, Hellström-Lindberg, E, Henter, J-I, Orrenius, S, Zhivotovsky, B

Journal:

Year:

1999

Language:

english

File:

PDF, 1.19 MB

english, 1999

59

Granulocyte colony-stimulating factor inhibits Fas-triggered apoptosis in bone marrow cells isolated from patients with refractory anemia with ringed sideroblasts

Schmidt-Mende, J, Tehranchi, R, Forsblom, A M, Joseph, B, Christensson, B, Fadeel, B, Zhivotovsky, B, Hellström-Lindberg, E

Journal:

Year:

2001

Language:

english

File:

PDF, 329 KB

english, 2001

60

The pharmacodynamic effect of busulfan in the P39 myeloid cell line in vitro

Hassan, Z, Hassan, M, Hellström-Lindberg, E

Journal:

Year:

2001

Language:

english

File:

PDF, 439 KB

english, 2001

61

No benefit from adding GM-CSF to induction chemotherapy in transforming myelodysplastic syndromes: better outcome in patients with less proliferative disease

Hast, R, Hellström-Lindberg, E, Ohm, L, Björkholm, M, Celsing, F, Dahl, I-M, Dybedal, I, Gahrton, G, Lindberg, G, Lerner, R

Journal:

Year:

2003

Language:

english

File:

PDF, 137 KB

english, 2003

62

Attitude towards remission induction for elderly patients with acute myeloid leukemia influences survival

Juliusson, G, Billström, R, Gruber, A, Hellström-Lindberg, E, Höglund, M, Karlsson, K, Stockelberg, D, Wahlin, A, Åström, M, Arnesson, C

Journal:

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

63

Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

Treppendahl, M. B., Qiu, X., Sogaard, A., Yang, X., Nandrup-Bus, C., Hother, C., Andersen, M. K., Kjeldsen, L., Mollgaard, L., Hellstrom-Lindberg, E.

Journal:

Year:

2012

Language:

english

File:

PDF, 627 KB

english, 2012

64

Abstract: treatment of patients with myelodysplastic syndromes with G-CSF and erythropoietin

Eva Hellström-lindberg, Gunnar BirgegÅrd, Magnus Carlsson, Jan Carneskog, Inger-Marie Dahl, Ingunn Dybedal, Gunnar Grimfors, Karl Merk, Jon-Magnus Tangen, Ingemar Winqvist, Åke Öst, Anders Fasth, Gunn

Journal:

Medical Oncology

Year:

1993

Language:

english

File:

PDF, 500 KB

english, 1993

65

Variable growth in vitro of chromosomally different stem cells in myelodysplastic syndromes

Birgitta Swolin, Inge Högh Kristiansen, Stig Rödjer, Eva Hellström-Lindberg

Journal:

Leukemia Research

Year:

1993

Language:

english

File:

PDF, 491 KB

english, 1993

66

In vitro suspension culture reactions to 1,25 dihydroxyvitamin D3 in relation to bone marrow morphology and prognosis in patients with myelodysplastic syndromes

Eva Hellström-Lindberg, Karl-Henrik Robèrt, Birgitta Åhnsén, Annika Elmhorn-Rosenborg, Yvonne Kock, Åke Öst

Journal:

Leukemia Research

Year:

1992

Language:

english

File:

PDF, 647 KB

english, 1992

67

Synergistic effect of G-CSF and epo on the anaemia in patients with MDS. Evidence for increased erythropoietic effectiveness rather than expansion

E. Hellström-Lindberg, M. Carlsson, J. Carneskog, I.M. Dahl, I. Dybedal, G. Grimfors, C. Lindemalm, O. Linder, E. Löfvenberg, H. Nilsson-Ehle, J.M. Tangen, I. Turesson, I. Winquist, G. Öberg, Y. Begin

Journal:

Leukemia Research

Year:

1994

Language:

english

File:

PDF, 184 KB

english, 1994

68

Prediction of response to G-CSF and epo treatment for the anaemia of myelodysplastic syndromes (MDS)

Eva Hellström-Lindberg, Robert Negrin, Richard Stein, Sanford Krantz, James Vardiman, Åke Öst, Peter Greenberg

Journal:

Leukemia Research

Year:

1994

Language:

english

File:

PDF, 163 KB

english, 1994

69

A pharmacodynamic study of 5-azacytidine in the P39 cell line

Rasheed Khan, Anni Aggerholm, Peter Hokland, Moustapha Hassan, Eva Hellström-Lindberg

Journal:

Experimental Hematology

Year:

2006

Language:

english

File:

PDF, 475 KB

english, 2006

70

Hypomethylation and apoptosis in 5-azacytidine–treated myeloid cells

Rasheed Khan, Jan Schmidt-Mende, Mohsen Karimi, Vladimir Gogvadze, Moustapha Hassan, Tomas J. Ekström, Boris Zhivotovsky, Eva Hellström-Lindberg

Journal:

Experimental Hematology

Year:

2008

Language:

english

File:

PDF, 882 KB

english, 2008

71

New clues to the molecular pathogenesis of myelodysplastic syndromes

Martin Jädersten, Eva Hellström-Lindberg

Journal:

Experimental Cell Research

Year:

2010

Language:

english

File:

PDF, 576 KB

english, 2010

72

Freezing induces artificial cleavage of apoptosis-related proteins in human bone marrow cells

Jan Schmidt-Mende, Eva Hellström-Lindberg, Bertrand Joseph, Boris Zhivotovsky

Journal:

Journal of Immunological Methods

Year:

2000

Language:

english

File:

PDF, 158 KB

english, 2000

73

High-dose chemotherapy and APSCT as a potential cure for relapsing hemolysing AILD

Jenny Lindahl, Eva Kimby, Bo Björkstrand, Birger Christensson, Eva Hellström-Lindberg

Journal:

Leukemia Research

Year:

2001

Language:

english

File:

PDF, 814 KB

english, 2001

74

Best supportive care for the anaemia of myelodysplasia: inclusion of recombinant erythropoietin therapy?

David T Bowen, Eva Hellstrom-Lindberg

Journal:

Leukemia Research

Year:

2001

Language:

english

File:

PDF, 45 KB

english, 2001

75

Morphological changes and apoptosis in bone marrow from patients with myelodysplastic syndromes treated with granulocyte-CSF and erythropoietin

Eva Hellström-Lindberg, Lena Kanter-Lewensohn, Å Öst

Journal:

Leukemia Research

Year:

1997

Language:

english

File:

PDF, 1.07 MB

english, 1997

76

168 Low-dose chemotherapy in MDS

Eva Hellström-Lindberg

Journal:

Leukemia Research

Year:

1997

Language:

english

File:

PDF, 152 KB

english, 1997

77

152 Clinical results of the use of different cytokines in MDS

Eva Hellström-Lindberg

Journal:

Leukemia Research

Year:

1997

Language:

english

File:

PDF, 127 KB

english, 1997

78

Two pathways of apoptosis induced with all-trans retinoic acid and etoposide in the myeloid cell line P39

Zuzana Hassan, Bengt Fadeel, Boris Zhivotovsky, Eva Hellström-Lindberg

Journal:

Experimental Hematology

Year:

1999

Language:

english

File:

PDF, 916 KB

english, 1999

79

A predictive model for the clinical response to low dose ara-C: a study of 102 patients with myelodysplastic syndromes or acute leukaemia

Eva Hellström-Lindberg, Karl-Henrik Robèrt, Gösta Gahrton, Greger Lindberg, Ann-Mari Forsblom, Yvonne Kock, Åke Öst

Journal:

British Journal of Haematology

Year:

1992

Language:

english

File:

PDF, 791 KB

english, 1992

80

G- and GM-CSF in oncology and oncological haematology

J. Harmenberg, M. Höglund, E. Hellström-Lindberg

Journal:

European Journal of Haematology

Year:

1994

Language:

english

File:

PDF, 2.73 MB

english, 1994

81

Analysis of CD34-positive cells in bone marrow from patients with myelodysplastic syndromes and acute myeloid leukemia and in normal individuals: a comparison between FACS analysis and immunohistochemistry

Lena Kanter-Lewensohn, Eva Hellström-Lindberg, Yvonne Kock, Annika Elmhorn-Rosenborg, Åke öst

Journal:

European Journal of Haematology

Year:

1996

Language:

english

File:

PDF, 500 KB

english, 1996

82

Management and supportive care measures for adverse events in patients with myelodysplastic syndromes treated with azacitidine

Valeria Santini, Pierre Fenaux, Ghulam J. Mufti, Eva Hellström-Lindberg, Lewis R. Silverman, Alan List, Steven D. Gore, John F. Seymour, Jay Backstrom, Charles L. Beach

Journal:

European Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 103 KB

english, 2010

83

Octreotide for nausea and vomiting after chemotherapy and stem-cell transplantation

Gunhild Nordesjö-Haglund, Berit Lönnqvist, Greger Lindberg, Eva Hellstrôm-Lindberg

Journal:

Year:

1999

Language:

english

File:

PDF, 71 KB

english, 1999

84

Identification of Novel Somatic Mutations in SF3B1, a Gene Encoding a Core Component of RNA Splicing Machinery, in Myelodysplasia with Ring Sideroblasts and Other Common Cancers

E. Papaemmanuil, L. Malcovati, M. Cazzola, E. Hellstrom-Lindberg, D. Bowen, J.B. Boultwood, A.R. Green, P.A. Futreal, M.R. Stratton, P.J. Campbell

Journal:

European Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 53 KB

english, 2011

85

Erythropoietins should be used according to guidelines

Matti S Aapro, Gunnar Birgegård, Carsten Bokemeyer, Paul Cornes, Jan Foubert, Pere Gascon, John Glaspy, Eva Hellström-Lindberg, Hartmut Link, Heinz Ludwig, Anders Österborg, Lazzaro Repetto, Pierre So

Journal:

The Lancet Oncology

Year:

2008

Language:

english

File:

PDF, 565 KB

english, 2008

86

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

Pierre Fenaux, Ghulam J Mufti, Eva Hellstrom-Lindberg, Valeria Santini, Carlo Finelli, Aristoteles Giagounidis, Robert Schoch, Norbert Gattermann, Guillermo Sanz, Alan List, Steven D Gore, John F Seym

Journal:

The Lancet Oncology

Year:

2009

Language:

english

File:

PDF, 232 KB

english, 2009

87

Management of anemia associated with myelodysplastic syndrome

E. Hellström-Lindberg

Journal:

Seminars in Hematology

Year:

2005

Language:

english

File:

PDF, 247 KB

english, 2005

88

Supportive Care and Use of Hematopoietic Growth Factors in Myelodysplastic Syndromes

Eva Hellström-Lindberg, Luca Malcovati

Journal:

Seminars in Hematology

Year:

2008

Language:

english

File:

PDF, 329 KB

english, 2008

89

Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation

Grövdal, M, Karimi, M, Tobiasson, M, Reinius, L, Jansson, M, Ekwall, K, Ungerstedt, J, Kere, J, Greco, D, Hellström-Lindberg, E

Journal:

Year:

2014

Language:

english

File:

PDF, 844 KB

english, 2014

90

Identification of Gene Expression-Based Prognostic Markers in the Hematopoietic Stem Cells of Patients With Myelodysplastic Syndromes

Pellagatti, A., Benner, A., Mills, K. I., Cazzola, M., Giagounidis, A., Perry, J., Malcovati, L., Della Porta, M. G., Jadersten, M., Verma, A., McDonald, E.-J., Killick, S., Hellstrom-Lindberg, E., Bu

Journal:

Journal of Clinical Oncology

Year:

2013

Language:

english

File:

PDF, 291 KB

english, 2013

91

Myeloid leukaemia in systemic lupus erythematosus--a nested case-control study based on Swedish registers

Lofstrom, B., Backlin, C., Sundstrom, C., Hellstrom-Lindberg, E., Ekbom, A., Lundberg, I. E.

Journal:

Year:

2009

Language:

english

File:

PDF, 97 KB

english, 2009

92

Bone marrow dendritic cells are reduced in patients with high-risk myelodysplastic syndromes

Saft, Leonie, Björklund, Elisabet, Berg, Elisabeth, Hellström-Lindberg, Eva, Porwit, Anna

Journal:

Leukemia Research

Year:

2013

Language:

english

File:

PDF, 397 KB

english, 2013

93

Challenges of phase III trial design for novel treatments in diseases with no standard treatment: The AZA-001 myelodysplasia study model

Fenaux, Pierre, Seymour, John F., Santini, Valeria, Silverman, Lew, Gore, Steven, List, Alan, Sanz, Guillermo, Mufti, Ghulam J., Estey, Eli, Swern, Arlene S., Beach, C.L., Hellstrom-Lindberg, Eva

Journal:

Leukemia Research

Year:

2014

Language:

english

File:

PDF, 492 KB

english, 2014

94

P-110 Evaluation of a high throughput mutation-screening strategy in myelodysplastic syndrome patients and acute myeloid leukemia using Halogenomics™ targeted-gene enrichment technology

Karimi, M., Dimitriou, M., Nilsson, C., Jansson, M., Matsson, H., Unneberg, P., Lehmann, S., Kere, J., Hellström-Lindberg, E.

Journal:

Leukemia Research

Year:

2013

Language:

english

File:

PDF, 86 KB

english, 2013

95

IVA.2 Managing myelodysplastic syndromes in the frail elderly

Hellström-Lindberg, E.

Journal:

Critical Reviews in Oncology/Hematology

Year:

2007

Language:

english

File:

PDF, 54 KB

english, 2007

96

P-005 Aberrant splicing during erythroid differentiation in SF3B1 mutated sideroblastic anemia

Conte, S., Vesterlund, L., Katayama, S., Karimi, M., Unneberg, P., Papaemmanuil, E., Jansson, M., Mortera-Blanco, T., Dimitriou, M., Sander, B., Skoog, T., Campbell, P., Kere, J., Hellström-Lindberg,

Journal:

Leukemia Research

Year:

2013

Language:

english

File:

PDF, 156 KB

english, 2013

97

Erythropoiesis stimulating agents and other growth factors in low-risk MDS

Hellström-Lindberg, Eva, van de Loosdrecht, Arjan

Journal:

Best Practice & Research Clinical Haematology

Year:

2013

Language:

english

File:

PDF, 240 KB

english, 2013

98

Safety and Efficacy of Romiplostim in Patients With Lower-Risk Myelodysplastic Syndrome and Thrombocytopenia

Kantarjian, H., Fenaux, P., Sekeres, M. A., Becker, P. S., Boruchov, A., Bowen, D., Hellstrom-Lindberg, E., Larson, R. A., Lyons, R. M., Muus, P., Shammo, J., Siegel, R., Hu, K., Franklin, J., Berger,

Journal:

Journal of Clinical Oncology

Year:

2010

Language:

english

File:

PDF, 281 KB

english, 2010

99

Efficacy of erythropoietin in the myelodysplastic syndromes: a meta-analysis of 205 patients from 17 studies

Hellström-Lindberg, Eva

Journal:

British Journal of Haematology

Year:

1995

Language:

english

File:

PDF, 402 KB

english, 1995

100

Early detection of relapse in patients with myelodysplastic syndrome after allo-SCT

Tobiasson, M, Olsson, R, Hellström-Lindberg, E, Mattsson, J

Journal:

Bone Marrow Transplantation

Year:

2011

Language:

english

File:

PDF, 433 KB

english, 2011