Helmtrude I. Roach: search on Z-Library

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1

Bone-like Resorbable Silk-based Scaffolds for Load-bearing Osteoregenerative Applications

Andrew M. Collins, Nick J. V. Skaer, Tom Gheysens, David Knight, Caroline Bertram, Helmtrud I. Roach, Richard O. C. Oreffo, Sonja Von-Aulock, Teodora Baris, John Skinner, Stephen Mann

Journal:

Advanced Materials

Year:

2009

Language:

english

File:

PDF, 425 KB

english, 2009

2

Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions

Helmtrud I. Roach, Norikazu Yamada, Kelvin S. C. Cheung, Simon Tilley, Nicholas M. P. Clarke, Richard O. C. Oreffo, Shoichi Kokubun, Felix Bronner

Journal:

Arthritis & Rheumatism

Year:

2005

Language:

english

File:

PDF, 423 KB

english, 2005

3

The complex pathology of osteoarthritis: Even mitochondria are involved

Helmtrud I. Roach

Journal:

Arthritis & Rheumatism

Year:

2008

Language:

english

File:

PDF, 37 KB

english, 2008

4

DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes

Ko Hashimoto, Richard O. C. Oreffo, Marc B. Gibson, Mary B. Goldring, Helmtrud I. Roach

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 553 KB

english, 2009

5

A new role for the chondrocyte in fracture repair: Endochondral ossification includes direct bone formation by former chondrocytes

Miss Brigitte E. Scammell, Helmtrud I. Roach

Journal:

Journal of Bone and Mineral Research

Year:

1996

Language:

english

File:

PDF, 5.48 MB

english, 1996

6

HSPG modulation of BMP signaling in fibrodysplasia ossificans progressiva cells

Michael P. O'Connell, Paul C. Billings, Jennifer L. Fiori, Gregory Deirmengian, Helmtrud I. Roach, Eileen M. Shore, Frederick S. Kaplan

Journal:

Journal of Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 283 KB

english, 2007

7

Cellular and epigenetic features of a young healthy and a young osteoarthritic cartilage compared with aged control and OA cartilage

Marco A. da Silva, Norikazu Yamada, Nicholas M.P. Clarke, Helmtrud I. Roach

Journal:

Journal of Orthopaedic Research

Year:

2009

Language:

english

File:

PDF, 633 KB

english, 2009

8

An ex vivo model for chondrogenesis and osteogenesis

Jodie C. Pound, David W. Green, Helmtrud I. Roach, Stephen Mann, Richard O.C. Oreffo

Journal:

Year:

2007

Language:

english

File:

PDF, 2.25 MB

english, 2007

9

Induction of normal and dystrophic mineralization by glycerophosphates in long-term bone organ culture

Helmtrud I. Roach

Journal:

Calcified Tissue International

Year:

1992

Language:

english

File:

PDF, 4.33 MB

english, 1992

10

Expression of ADAMTS-4 by chondrocytes in the surface zone of human osteoarthritic cartilage is regulated by epigenetic DNA de-methylation

Kelvin S. C. Cheung, Ko Hashimoto, Norikazu Yamada, Helmtrud I. Roach

Journal:

Rheumatology International

Year:

2009

Language:

english

File:

PDF, 623 KB

english, 2009

11

Apoptotic cell nuclei favour aggregation and fluorescence quenching of DNA dyes

J. Erenpreisa, Talivaldis Freivalds, Helmtrud Roach, Roger Alston

Journal:

Histochemistry and Cell Biology

Year:

1997

Language:

english

File:

PDF, 526 KB

english, 1997

12

Catabolic and anabolic phases of osteodystrophy in aged rats

Helmtrud I. Roach, Nicholas M.P. Clarke, Simon Langley-Evans, Cyrus Cooper

Journal:

Journal of Bone and Mineral Metabolism

Year:

2003

Language:

english

File:

PDF, 594 KB

english, 2003

13

Selective synthesis of bone morphogenetic proteins-1, -3, -4 and bone sialoprotein may be important for osteoinduction by Saos-2 cells

H. Clarke Anderson, Paul R. Reynolds, Howard H. T. Hsu, Lilliana Missana, Kensaku Masuhara, Paul E. Moylan, Helmtrude I. Roach

Journal:

Journal of Bone and Mineral Metabolism

Year:

2002

Language:

english

File:

PDF, 233 KB

english, 2002

14

Changes in the antiangiogenic properties of articular cartilage in osteoarthritis

James O. Smith, Richard O.C. Oreffo, Nicholas M.P. Clarke, Helmtrud I. Roach

Journal:

Journal of Orthopaedic Science

Year:

2003

Language:

english

File:

PDF, 364 KB

english, 2003

15

Histological abnormalities of the calcaneum in congenital talipes equinovarus

James A. Gilbert, Helmtrud I. Roach, Nicholas M. P. Clarke

Journal:

Journal of Orthopaedic Science

Year:

2001

Language:

english

File:

PDF, 821 KB

english, 2001

16

Prenatal and Nutritional Influences on Skeletal Development: Lessons from Animal Studies

Stuart A. Lanham, Helmtrud I. Roach, Cyrus Cooper, Richard O. C. Oreffo

Journal:

Clinical Reviews in Bone and Mineral Metabolism

Year:

2010

Language:

english

File:

PDF, 418 KB

english, 2010

17

Aberrant death in dark chondrocytes of the avian growth plate

Erenpreisa, Jekaterina, Roach, Helmtrud I

Journal:

Cell Death & Differentiation

Year:

1998

Language:

english

File:

PDF, 595 KB

english, 1998

18

New Aspects of Endochondral Ossification in the Chick: Chondrocyte Apoptosis, Bone Formation by Former Chondrocytes, and Acid Phosphatase Activity in the Endochondral Bone Matrix

Helmtrud I. Roach

Journal:

Journal of Bone and Mineral Research

Year:

1997

Language:

english

File:

PDF, 712 KB

english, 1997

19

Initiation of the Bony Epiphysis in Long Bones: Chronology of Interactions Between the Vascular System and the Chondrocytes

Helmtrud I. Roach, Janice E. Baker, Nicholas M. P. Clarke

Journal:

Journal of Bone and Mineral Research

Year:

1998

Language:

english

File:

PDF, 696 KB

english, 1998

20

“Cell Paralysis” as an Intermediate Stage in the Programmed Cell Death of Epiphyseal Chondrocytes During Development

Helmtrud I. Roach, Nicholas M. P. Clarke

Journal:

Journal of Bone and Mineral Research

Year:

1999

Language:

english

File:

PDF, 4.48 MB

english, 1999

21

Pleiotrophin/Osteoblast-Stimulating Factor 1: Dissecting Its Diverse Functions in Bone Formation

Rahul S. Tare, Richard O. C. Oreffo, Nicholas M. P. Clarke, Helmtrud I. Roach

Journal:

Journal of Bone and Mineral Research

Year:

2002

Language:

english

File:

PDF, 20.31 MB

english, 2002

22

Induction of Human Osteoprogenitor Chemotaxis, Proliferation, Differentiation, and Bone Formation by Osteoblast Stimulating Factor-1/Pleiotrophin: Osteoconductive Biomimetic Scaffolds for Tissue Engineering

Xuebin Yang, Rahul S Tare, Kris A Partridge, Helmtrud I Roach, Nicholas MP Clarke, Steven M Howdle, Kevin M Shakesheff, Richard OC Oreffo

Journal:

Journal of Bone and Mineral Research

Year:

2003

Language:

english

File:

PDF, 21.94 MB

english, 2003

23

Association of Matrix Acid and Alkaline Phosphatases with Mineralization of Cartilage and Endochondral Bone

Helmtrud I. Roach

Journal:

Journal of Molecular Histology

Year:

1999

Language:

english

File:

PDF, 183 KB

english, 1999

24

Characterization and Multipotentiality of Human Fetal Femur–Derived Cells: Implications for Skeletal Tissue Regeneration

Sayed-Hadi Mirmalek-Sani, Rahul S. Tare, Suzanne M. Morgan, Helmtrud I. Roach, David I. Wilson, Neil A. Hanley, Richard O.C. Oreffo

Journal:

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

25

Bone-Metabolic Functions and Modulators Volume 137 || Thyroid and Thyroid Hormone: Normal Function, Diseases, Disorders, Emerging Therapeutics

Bronner, Felix, Farach-Carson, Mary C., Roach, Helmtrud I.

Year:

2012

Language:

english

File:

PDF, 522 KB

english, 2012

26

Long-term organ culture of embryonic chick femora: A system for investigating bone and cartilage formation at an intermediate level of organization

Helmtrud I. Roach

Journal:

Journal of Bone and Mineral Research

Year:

1990

Language:

english

File:

PDF, 5.05 MB

english, 1990

27

Aberrations of cell cycle and cell death in normal development of the chick embryo growth plate

Jekaterina Erenpreisa, Helmtrud I. Roach

Journal:

Mechanisms of Ageing and Development

Year:

1999

Language:

english

File:

PDF, 2.74 MB

english, 1999

28

Bone-Metabolic Functions and Modulators Volume 7440 || Glucocorticoids, Inflammation, and Bone

Bronner, Felix, Farach-Carson, Mary C., Roach, Helmtrud I.

Year:

2012

Language:

english

File:

PDF, 358 KB

english, 2012

29

Tissue engineering strategies for cartilage generation—Micromass and three dimensional cultures using human chondrocytes and a continuous cell line

Rahul S. Tare, Daniel Howard, Jodie C. Pound, Helmtrud I. Roach, Richard O.C. Oreffo

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 4.21 MB

english, 2005

30

The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes – Implications for osteoarthritis

Kei Imagawa, MC de Andrés, Ko Hashimoto, Dominic Pitt, Eiji Itoi, Mary B. Goldring, Helmtrud I. Roach, Richard O.C. Oreffo

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 631 KB

english, 2011

31

Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis

María C. de Andrés, Kei Imagawa, Ko Hashimoto, Antonio Gonzalez, Mary B. Goldring, Helmtrud I. Roach, Richard O.C. Oreffo

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 744 KB

english, 2011

32

Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A

Ahmed T. El-Serafi, Richard O.C. Oreffo, Helmtrud I. Roach

Journal:

Differentiation

Year:

2011

Language:

english

File:

PDF, 1.23 MB

english, 2011

33

Effects of targeted overexpression of pleiotrophin on postnatal bone development

Rahul S Tare, Richard O.C Oreffo, Kenzo Sato, Heikki Rauvala, Nicholas M.P Clarke, Helmtrud I Roach

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 570 KB

english, 2002

34

Maternal protein deficiency affects mesenchymal stem cell activity in the developing offspring

Richard O.C Oreffo, Benjamin Lashbrooke, Helmtrud I Roach, Nicholas M.P Clarke, Cyrus Cooper

Journal:

Year:

2003

Language:

english

File:

PDF, 251 KB

english, 2003

35

Epigenetic Aspects of Chronic Diseases || Mechanisms of Epigenetic Gene Silencing

Roach, Helmtrud I., Bronner, Felix, Oreffo, Richard O.C.

Year:

2011

Language:

english

File:

PDF, 2.06 MB

english, 2011

36

Epigenetic Aspects of Chronic Diseases || Epigenetics and Chronic Diseases: An Overview

Roach, Helmtrud I., Bronner, Felix, Oreffo, Richard O.C.

Year:

2011

Language:

english

File:

PDF, 2.13 MB

english, 2011

37

Epigenetic Aspects of Chronic Diseases || Mechanisms of Epigenetic Gene Activation in Disease: Dynamics of DNA Methylation and Demethylation

Roach, Helmtrud I., Bronner, Felix, Oreffo, Richard O.C.

Year:

2011

Language:

english

File:

PDF, 1.74 MB

english, 2011

38

Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes

de Andrés, María C., Imagawa, Kei, Hashimoto, Ko, Gonzalez, Antonio, Roach, Helmtrud I., Goldring, Mary B., Oreffo, Richard O. C.

Journal:

Arthritis & Rheumatism

Year:

2013

Language:

english

File:

PDF, 393 KB

english, 2013

39

Bone-Metabolic Functions and Modulators || Osteoimmunology: Relation to Disease and Therapy

Bronner, Felix, Farach-Carson, Mary C., Roach, Helmtrud I.

Year:

2012

Language:

english

File:

PDF, 525 KB

english, 2012

40

Bone-Metabolic Functions and Modulators ||

Bronner, Felix, Farach-Carson, Mary C., Roach, Helmtrud I.

Year:

2012

Language:

english

File:

PDF, 7.15 MB

english, 2012

41

Epigenetic Aspects of Chronic Diseases || The Role of Histone Demethylases in Disease

Roach, Helmtrud I., Bronner, Felix, Oreffo, Richard O.C.

Year:

2011

Language:

english

File:

PDF, 2.45 MB

english, 2011

42

Epigenetic Aspects of Chronic Diseases ||

Roach, Helmtrud I., Bronner, Felix, Oreffo, Richard O.C.

Year:

2011

Language:

english

File:

PDF, 8.32 MB

english, 2011

43

Epigenetic Aspects of Chronic Diseases || Epigenetics of Rheumatoid Arthritis

Roach, Helmtrud I., Bronner, Felix, Oreffo, Richard O.C.

Year:

2011

Language:

english

File:

PDF, 2.42 MB

english, 2011

44

Epigenetic Aspects of Chronic Diseases || Techniques to Study DNA Methylation and Histone Modification

Roach, Helmtrud I., Bronner, Felix, Oreffo, Richard O.C.

Year:

2011

Language:

english

File:

PDF, 1.68 MB

english, 2011

45

Apoptosis in osteoarthritis

Aigner, Thomas, Kim, Hyun A, Roach, Helmtrud I

Journal:

Rheumatic Disease Clinics of North America

Year:

2004

Language:

english

File:

PDF, 467 KB

english, 2004

46

Cartilage resorption and endochondral bone formation during the development of long bones in chick embryos

Roach, Helmtrud I., Shearer, John R.

Journal:

Bone and Mineral

Year:

1989

Language:

english

File:

PDF, 3.65 MB

english, 1989

47

Osteogenic Differentiation of Hypertrophic Chondrocytes Involves Asymmetric Cell Divisions and Apoptosis

Helmtrud I. Roach, Jekaterina Erenpreisa and Thomas Aigner

Journal:

The Journal of Cell Biology

Year:

1995

Language:

english

File:

PDF, 3.03 MB

english, 1995

48

Strategies to Promote Chondrogenesis and Osteogenesis from Human Bone Marrow Cells and Articular Chondrocytes Encapsulated in Polysaccharide Templates

Pound, Jodie C., Green, David W., Chaudhuri, Julian B., Mann, Stephen, Roach, Helmtrud I., Oreffo, Richard O.C.

Journal:

Tissue Engineering

Year:

2006

Language:

english

File:

PDF, 3.51 MB

english, 2006

49

Improved Quantification of DNA Methylation Using Methylation-Sensitive Restriction Enzymes and Real-Time PCR

Hashimoto, Ko, Kokubun, Shoichi, Itoi, Eiji, Roach, Helmtrud I.

Journal:

Year:

2007

Language:

english

File:

PDF, 430 KB

english, 2007

50

Association of Reduced Type IX Collagen Gene Expression in Human Osteoarthritic Chondrocytes With Epigenetic Silencing by DNA Hypermethylation

Imagawa, Kei, de Andrés, María C., Hashimoto, Ko, Itoi, Eiji, Otero, Miguel, Roach, Helmtrud I., Goldring, Mary B., Oreffo, Richard O. C.

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 637 KB

english, 2014