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51

Effects of Mild Cognitive Impairment on Driving Performance in Older Drivers

Naoko Kawano, Kunihiro Iwamoto, Kazutoshi Ebe, Yusuke Suzuki, Jun Hasegawa, Katsuyuki Ukai, Hiroyuki Umegaki, Tetsuya Iidaka, Norio Ozaki

Journal:

Journal of the American Geriatrics Society

Year:

2012

Language:

english

File:

PDF, 114 KB

english, 2012

52

Risk factors for a 6-year decline in physical disability and functional limitations among elderly people with type 2 diabetes in the Japanese elderly diabetes intervention trial

Takashi Sakurai, Satoshi Iimuro, Kentaro Sakamaki, Hiroyuki Umegaki, Atsushi Araki, Yasuo Ohashi, Hideki Ito, the Japanese Elderly Diabetes Intervention Trial Study Group

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 379 KB

english, 2012

53

Risk factors associated with cognitive decline in the elderly with type 2 diabetes: Baseline data analysis of the Japanese elderly diabetes intervention trial

Hiroyuki Umegaki, Satoshi Iimuro, Tomohiro Shinozaki, Atsushi Araki, Takashi Sakurai, Katsuya Iijima, Yasuo Ohashi, Hideki Ito, the Japanese Elderly Diabetes Intervention Trial Study Group

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 261 KB

english, 2012

54

Lower physical activity is a strong predictor of cardiovascular events in elderly patients with type 2 diabetes mellitus beyond traditional risk factors: The Japanese elderly diabetes intervention trial

Katsuya Iijima, Satoshi Iimuro, Tomohiro Shinozaki, Yasuo Ohashi, Takashi Sakurai, Hiroyuki Umegaki, Atsushi Araki, Yasuyoshi Ouchi, Hideki Ito, the Japanese Elderly Diabetes Intervention Trial Invest

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 411 KB

english, 2012

55

Relations of nutritional intake to age, sex and body mass index in Japanese elderly patients with type 2 diabetes: The Japanese Elderly Diabetes Intervention Trial

Yukio Yoshimura, Chiemi Kamada, Keiko Takahashi, Tae Kaimoto, Satoshi Iimuro, Yasuo Ohashi, Atsushi Araki, Hiroyuki Umegaki, Takashi Sakurai, Hideki Ito, the Japanese Elderly Diabetes Intervention Tri

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 180 KB

english, 2012

56

Dysphagia in older adults at high risk of requiring care

Hiroyuki Umegaki, Yusuke Suzuki, Madoka Yanagawa, Zen Nonogaki, Hirotaka Nakashima, Hidetoshi Endo

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 853 KB

english, 2012

57

Risk factors associated with cognitive decline in the elderly with type 2 diabetes: Pooled logistic analysis of a 6-year observation in the Japanese elderly diabetes intervention trial

Hiroyuki Umegaki, Satoshi Iimuro, Tomohiro Shinozaki, Atsushi Araki, Takashi Sakurai, Katsuya Iijima, Yasuo Ohashi, Hideki Ito, the Japanese Elderly Diabetes Intervention Trial Study Group

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 224 KB

english, 2012

58

Optimal energy distribution of carbohydrate intake for Japanese elderly patients with type 2 diabetes: The Japanese Elderly Intervention Trial

Chiemi Kamada, Hidenori Yoshimura, Ryota Okumura, Keiko Takahashi, Satoshi Iimuro, Yasuo Ohashi, Atsushi Araki, Hiroyuki Umegaki, Takashi Sakurai, Yukio Yoshimura, Hideki Ito, the Japanese Elderly Dia

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 167 KB

english, 2012

59

Factors associated with progression of diabetic nephropathy in Japanese elderly patients with type 2 diabetes: Sub-analysis of the Japanese Elderly Diabetes Intervention Trial

Shin-ichi Araki, Yoshihiko Nishio, Atsushi Araki, Hiroyuki Umegaki, Takashi Sakurai, Satoshi Iimuro, Yasuo Ohashi, Takashi Uzu, Hiroshi Maegawa, Atsunori Kashiwagi, Hideki Ito, the Japanese Elderly In

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 292 KB

english, 2012

60

Non-high-density lipoprotein cholesterol: An important predictor of stroke and diabetes-related mortality in Japanese elderly diabetic patients

Atsushi Araki, Satoshi Iimuro, Takashi Sakurai, Hiroyuki Umegaki, Katsuya Iijima, Hiroshi Nakano, Kenzo Oba, Koichi Yokono, Hirohito Sone, Nobuhiro Yamada, Junya Ako, Koichi Kozaki, Hisayuki Miura, At

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

61

Effects of total and green vegetable intakes on glycated hemoglobin A1c and triglycerides in elderly patients with type 2 diabetes mellitus: The Japanese Elderly Intervention Trial

Keiko Takahashi, Chiemi Kamada, Hidenori Yoshimura, Ryota Okumura, Satoshi Iimuro, Yasuo Ohashi, Atsushi Araki, Hiroyuki Umegaki, Takashi Sakurai, Yukio Yoshimura, Hideki Ito, the Japanese Elderly Dia

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 126 KB

english, 2012

62

Lower physical activity, but not excessive calorie intake, is associated with metabolic syndrome in elderly with type 2 diabetes mellitus: The Japanese elderly diabetes intervention trial

Katsuya Iijima, Satoshi Iimuro, Yasuo Ohashi, Takashi Sakurai, Hiroyuki Umegaki, Atsushi Araki, Yukio Yoshimura, Yasuyoshi Ouchi, Hideki Ito, the Japanese Elderly Diabetes Intervention Trial Study Gro

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 359 KB

english, 2012

63

Dietary pattern and mortality in Japanese elderly patients with type 2 diabetes mellitus: Does a vegetable- and fish-rich diet improve mortality? An explanatory study

Satoshi Iimuro, Yukio Yoshimura, Hiroyuki Umegaki, Takashi Sakurai, Atsushi Araki, Yasuo Ohashi, Katsuya Iijima, Hideki Ito, the Japanese Elderly Diabetes Intervention Trial Study Group

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 401 KB

english, 2012

64

Cognitive impairments and functional declines in older adults at high risk for care needs

Hiroyuki Umegaki, Yusuke Suzuki, Madoka Yanagawa, Zen Nonogaki, Hirotaka Nakashima, Masufumi Kuzuya, Hidetoshi Endo

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 116 KB

english, 2012

65

Active formation of an antiguide structure in a photorefractive polymer for enhanced second-harmonic generation

Sassa, Takafumi, Wada, Tatsuo, Sasabe, Hiroyuki, Yokoyama, Masaaki, Umegaki, Shinsuke

Journal:

Year:

2001

Language:

english

File:

PDF, 137 KB

english, 2001

66

Protective effect of interleukin-6 against the death of PC12 cells caused by serum deprivation or by the addition of a calcium ionophore

Hiroyuki Umegaki, Kiyofumi Yamada, Michitaka Naito, Tsutomu Kameyama, Akihisa Iguchi, Toshitaka Nabeshima

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 713 KB

english, 1996

67

Defects in cytokine-mediated neuroprotective glial responses to excitotoxic hippocampal injury in senescence-accelerated mouse

Sanae Hasegawa-Ishii, Shiro Takei, Muneo Inaba, Hiroyuki Umegaki, Yoichi Chiba, Ayako Furukawa, Noriko Kawamura, Masanori Hosokawa, Atsuyoshi Shimada

Journal:

Brain, Behavior, and Immunity

Year:

2011

Language:

english

File:

PDF, 3.67 MB

english, 2011

68

Long-term effects of a diet loosely restricting carbohydrates on HbA1c levels, BMI and tapering of sulfonylureas in type 2 diabetes: A 2-year follow-up study

Hajime Haimoto, Mitsunaga Iwata, Kenji Wakai, Hiroyuki Umegaki

Journal:

Diabetes Research and Clinical Practice

Year:

2008

Language:

english

File:

PDF, 198 KB

english, 2008

69

Does cerebral small vessel disease predict future decline of cognitive function in elderly people with type 2 diabetes?

Rui Imamine, Takahiko Kawamura, Toshitaka Umemura, Hiroyuki Umegaki, Naoko Kawano, Megumi Hotta, Yu Kouchi, Sawako Hatsuda, Atsuko Watarai, Akio Kanai, Eitaro Nakashima, Takahisa Sano, Toshimasa Sakak

Journal:

Diabetes Research and Clinical Practice

Year:

2011

Language:

english

File:

PDF, 421 KB

english, 2011

70

Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: Effects on ethanol drinking

Panayotis K. Thanos, Seth N. Rivera, Katrina Weaver, David K. Grandy, Marcelo Rubinstein, Hiroyuki Umegaki, Gene Jack Wang, Robert Hitzemann, Nora D. Volkow

Journal:

Year:

2005

Language:

english

File:

PDF, 121 KB

english, 2005

71

Factors associated with lower Mini Mental State Examination scores in elderly Japanese diabetes mellitus patients

Hiroyuki Umegaki, Satoshi Iimuro, Tetsuji Kaneko, Atsushi Araki, Takashi Sakurai, Yasuo Ohashi, Akihisa Iguchi, Hideki Ito

Journal:

Neurobiology of Aging

Year:

2008

Language:

english

File:

PDF, 111 KB

english, 2008

72

Ginkgo biloba extract-induced relaxation of rat aorta is associated with increase in endothelial intracellular calcium level

Yoko Kubota, Naoko Tanaka, Keizo Umegaki, Hiroyuki Takenaka, Hideya Mizuno, Kazuki Nakamura, Kazumasa Shinozuka, Masaru Kunitomo

Journal:

Year:

2001

Language:

english

File:

PDF, 265 KB

english, 2001

73

Dietary restriction of choline reduces hippocampal acetylcholine release in rats: In vivo microdialysis study

Akira Nakamura, Yusuke Suzuki, Hiroyuki Umegaki, Hiroyuki Ikari, Toshihisa Tajima, Hidetoshi Endo, Akihisa Iguchi

Journal:

Brain Research Bulletin

Year:

2001

Language:

english

File:

PDF, 111 KB

english, 2001

74

Possible Involvement of Catalase in the Protective Effect of Interleukin-6 Against 6-Hydroxydopamine Toxicity in PC12 Cells

Kiyofumi Yamada, Hiroyuki Umegaki, Izumi Maezawa, Akihisa Iguchi, Tsutomu Kameyama, Toshitaka Nabeshima

Journal:

Brain Research Bulletin

Year:

1997

Language:

english

File:

PDF, 463 KB

english, 1997

75

Positron emission tomography and ex vivo and in vitro autoradiography studies on dopamine D2-like receptor degeneration in the quinolinic acid-lesioned rat striatum: comparison of [11C]raclopride, [11C]nemonapride and [11C]N-methylspiperone

Kiichi Ishiwata, Nobuo Ogi, Nobutaka Hayakawa, Hiroyuki Umegaki, Tsukasa Nagaoka, Keiichi Oda, Hinako Toyama, Kazutoyo Endo, Akira Tanaka, Michio Senda

Journal:

Nuclear Medicine and Biology

Year:

2002

Language:

english

File:

PDF, 313 KB

english, 2002

76

Cognitive dysfunction: An emerging concept of a new diabetic complication in the elderly

Hiroyuki Umegaki, Toshio Hayashi, Hideki Nomura, Madoka Yanagawa, Zen Nonogaki, Hirotaka Nakshima, Masafumi Kuzuya

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 275 KB

english, 2012

77

P-183: Factors associated with lower cognitive function in old diabetic patients

Hiroyuki Umegaki, Satoshi Iimuro, Tetsuji Kaneko, Atsushi Araki, Takashi Sakurai, Yasuo Ohashi, Akihisa Iguchi, Hideki Ito

Journal:

Alzheimer's & Dementia

Year:

2007

Language:

english

File:

PDF, 60 KB

english, 2007

78

Acute metabolic responses to a high-carbohydrate meal in outpatients with type 2 diabetes treated with a low-carbohydrate diet: a crossover meal tolerance study

Hajime Haimoto, Tae Sasakabe, Hiroyuki Umegaki, Kenji Wakai

Journal:

Nutrition & Metabolism

Year:

2009

Language:

english

File:

PDF, 764 KB

english, 2009

79

Decreased interleukin-6 level in the cerebrospinal fluid of patients with Alzheimer-type dementia

Yamada, Kiyofumi, Kono, Kazuhiko, Umegaki, Hiroyuki, Yamada, Kazuyoshi, Iguchi, Akihisa, Fukatsu, Toshiaki, Nakashima, Nobou, Nishiwaki, Hirotshi, Shimada, Yasuhiro, Sugita, Yasuko, Yamamoto, Takayuki

Journal:

Neuroscience Letters

Year:

1995

Language:

english

File:

PDF, 268 KB

english, 1995

80

Relationship between small cerebral white matter lesions and cognitive function in patients with Alzheimer's disease and amnestic mild cognitive impairment

Makino, Taeko, Umegaki, Hiroyuki, Suzuki, Yusuke, Yanagawa, Madoka, Nonogaki, Zen, Nakashima, Hirotaka, Kuzuya, Masafumi

Journal:

Geriatrics & Gerontology International

Year:

2014

Language:

english

File:

PDF, 249 KB

english, 2014

81

The perception of dementia in the general population in Japan

Umegaki, Hiroyuki, Yanagawa, Madoka, Nonogaki, Zen, Nakashima, Takahiro, Suzuki, Yusuke, Kuzuya, Masafumi

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 66 KB

english, 2013

82

Impaired glycemia and Alzheimer's disease

Umegaki, Hiroyuki

Journal:

Neurobiology of Aging

Year:

2014

Language:

english

File:

PDF, 139 KB

english, 2014

83

Burden reduction of caregivers for users of care services provided by the public long-term care insurance system in Japan

Umegaki, Hiroyuki, Yanagawa, Madoka, Nonogaki, Zen, Nakashima, Hirotaka, Kuzuya, Masafumi, Endo, Hidetoshi

Journal:

Archives of Gerontology and Geriatrics

Year:

2014

Language:

english

File:

PDF, 275 KB

english, 2014

84

Differences in neuropsychological performance according to neuropsychiatric symptoms in patients with Alzheimer's disease

Makino, Taeko, Umegaki, Hiroyuki, Suzuki, Yusuke, Kuzuya, Masahumi

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 151 KB

english, 2012

85

Protective effects of probucol against glutamate-induced cytotoxicity in neuronal cell line PC12

Naito, Michitaka, Umegaki, Hiroyuki, Iguchi, Akihisa

Journal:

Neuroscience Letters

Year:

1995

Language:

english

File:

PDF, 309 KB

english, 1995

86

Three-graded stratification of carbohydrate restriction by level of baseline hemoglobin A1c for type 2 diabetes patients with a moderate low-carbohydrate diet

Hajime Haimoto,Tae Sasakabe,Takahiko Kawamura,Hiroyuki Umegaki…

Journal:

Nutrition & Metabolism

Year:

2014

Language:

english

File:

PDF, 948 KB

english, 2014

87

Protective Effects of Quercetin and Its Metabolites on H 2 O 2 -Induced Chromosomal Damage to WIL2-NS Cells

SAITO, Akiko, SUGISAWA, Ayako, UMEGAKI, Keizo, SUNAGAWA, Hiroyuki

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2004

Language:

english

File:

PDF, 113 KB

english, 2004

88

Insulin resistance in the brain: A new therapeutic target for Alzheimer's disease

Umegaki, Hiroyuki

Journal:

Journal of Diabetes Investigation

Year:

2013

Language:

english

File:

PDF, 108 KB

english, 2013

89

in a magnetic field and quantum sine-Gordon model

Umegaki, Izumi, Tanaka, Hidekazu, Ono, Toshio, Uekusa, Hidehiro, Nojiri, Hiroyuki

Journal:

Physical Review B

Year:

2009

Language:

english

File:

PDF, 425 KB

english, 2009

90

Effect of renal impairment on cognitive function during a 3-year follow up in elderly patients with type 2 diabetes: Association with microinflammation

Kawamura, Takahiko, Umemura, Toshitaka, Umegaki, Hiroyuki, Imamine, Rui, Kawano, Naoko, Tanaka, Chiai, Kawai, Mariko, Minatoguchi, Makiko, Kusama, Minoru, Kouchi, Yu, Watarai, Atsuko, Kanai, Akio, Nak

Journal:

Journal of Diabetes Investigation

Year:

2014

Language:

english

File:

PDF, 329 KB

english, 2014

91

Association of decrease in carbohydrate intake with reduction in abdominal fat during 3-month moderate low-carbohydrate diet among non-obese Japanese patients with type 2 diabetes

Sasakabe, Tae, Haimoto, Hajime, Umegaki, Hiroyuki, Wakai, Kenji

Journal:

Year:

2015

Language:

english

File:

PDF, 279 KB

english, 2015

92

Dementia: Type 2 diabetes has a slow and insidious effect on cognition

Umegaki, Hiroyuki

Journal:

Nature Reviews Neurology (formerly Nature Clinical Practice Neurology)

Year:

2015

Language:

english

File:

PDF, 117 KB

english, 2015

93

Increased recruitment of bone marrow-derived cells into the brain associated with altered brain cytokine profile in senescence-accelerated mice

Hasegawa-Ishii, Sanae, Inaba, Muneo, Li, Ming, Shi, Ming, Umegaki, Hiroyuki, Ikehara, Susumu, Shimada, Atsuyoshi

Journal:

Brain Structure and Function (Anatomy and Embryology 1891-2006)

Year:

2016

Language:

english

File:

PDF, 5.49 MB

english, 2016

94

The Clock Drawing Test as a Valid Screening Method for Mild Cognitive Impairment

Yamamoto, Sayaka, Mogi, Nanaka, Umegaki, Hiroyuki, Suzuki, Yusuke, Ando, Fujiko, Shimokata, Hiroshi, Iguchi, Akihisa

Journal:

Dementia and Geriatric Cognitive Disorders

Year:

2004

Language:

english

File:

PDF, 115 KB

english, 2004

95

Association of higher carbohydrate intake with depressive mood in elderly diabetic women

Umegaki, Hiroyuki, Iimuro, Satoshi, Araki, Atsushi, Sakurai, Takashi, Iguchi, Akihisa, Yoshimura, Yukio, Ohashi, Yasuo, Ito, Hideki

Journal:

Nutritional Neuroscience

Year:

2009

Language:

english

File:

PDF, 113 KB

english, 2009

96

Factors associated with cognitive decline in older adults with type 2 diabetes mellitus during a 6-year observation

Umegaki, Hiroyuki, Kawamura, Takahiko, Umemura, Toshitaka, Kawano, Naoko

Journal:

Geriatrics & Gerontology International

Year:

2015

Language:

english

File:

PDF, 126 KB

english, 2015

97

Effects of Mild Cognitive Impairment on the Development of Fear of Falling in Older Adults: A Prospective Cohort Study

Uemura, Kazuki, Shimada, Hiroyuki, Makizako, Hyuma, Doi, Takehiko, Tsutsumimoto, Kota, Lee, Sangyoon, Umegaki, Hiroyuki, Kuzuya, Masafumi, Suzuki, Takao

Journal:

Journal of the American Medical Directors Association

Year:

2015

Language:

english

File:

PDF, 444 KB

english, 2015

98

Age-Associated Increase in Abdominal Obesity and Insulin Resistance, and Usefulness of AHA/NHLBI Definition of Metabolic Syndrome for Predicting Cardiovascular Disease in Japanese Elderly with Type 2 Diabetes Mellitus

Sakurai, Takashi, Iimuro, Satoshi, Araki, Atsushi, Umegaki, Hiroyuki, Ohashi, Yasuo, Yokono, Koichi, Ito, Hideki

Journal:

Year:

2010

Language:

english

File:

PDF, 209 KB

english, 2010

99

Factors Associated with Cognitive Decline in Elderly Diabetics

Umegaki, Hiroyuki, Kawamura, Takahiko, Kawano, Naoko, Umemura, Toshitaka, Kanai, Akio, Sano, Takahisa

Journal:

Dementia and Geriatric Cognitive Disorders Extra

Year:

2011

Language:

english

File:

PDF, 1001 KB

english, 2011

100

Incidence of lymph node metastasis in intramucosal gastric cancer measuring 30 mm or less, with ulceration; mixed, predominantly differentiated-type histology; and no lymphovascular invasion: a multicenter retrospective study

Takizawa, Kohei, Ono, Hiroyuki, Yamamoto, Yorimasa, Katai, Hitoshi, Hori, Shinichiro, Yano, Tomonori, Umegaki, Eiji, Sasaki, Shunya, Iizuka, Toshiro, Kawagoe, Kei, Shimoda, Tadakazu, Muto, Manabu, Sas

Journal:

Year:

2015

Language:

english

File:

PDF, 354 KB

english, 2015

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