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51

The Virtues of Unique Ribonucleotide Reductase Inhibitors Didox and Trimidox for Retrovirus Therapy

Howard Elford, Ron Lee, Jadwiga Turchan, Vincent Gallicchio, Michael Ussery, John Hiscott, Avindra Nath

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 70 KB

english, 2007

52

Regulatory studies of murine methylenetetrahydrofolate reductase reveal two major promoters and NF-κB sensitivity

Laura Pickell, Pamela Tran, Daniel Leclerc, John Hiscott, Rima Rozen

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2005

Language:

english

File:

PDF, 539 KB

english, 2005

53

Distinct functions of IRF-3 and IRF-7 in IFN-alpha gene regulation and control of anti-tumor activity in primary macrophages

Mayra Solis, Delphine Goubau, Raphaëlle Romieu-Mourez, Pierre Genin, Ahmet Civas, John Hiscott

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 687 KB

english, 2006

54

Recruitment of an interferon molecular signaling complex to the mitochondrial membrane: Disruption by hepatitis C virus NS3-4A protease

John Hiscott, Judith Lacoste, Rongtuan Lin

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 653 KB

english, 2006

55

Gene expression profiling of the host response to HIV-1 B, C, or A/E infection in monocyte-derived dendritic cells

Mayra Solis, Peter Wilkinson, Raphaelle Romieu, Eduardo Hernandez, Mark A. Wainberg, John Hiscott

Journal:

Year:

2006

Language:

english

File:

PDF, 972 KB

english, 2006

56

Bax-dependent mitochondrial membrane permeabilization enhances IRF3-mediated innate immune response during VSV infection

Ehssan Sharif-Askari, Peyman Nakhaei, Stephanie Oliere, Vanessa Tumilasci, Eduardo Hernandez, Peter Wilkinson, Rongtuan Lin, John Bell, John Hiscott

Journal:

Year:

2007

Language:

english

File:

PDF, 2.01 MB

english, 2007

57

Multiple signaling pathways leading to the activation of interferon regulatory factor 3

Marc J Servant, Nathalie Grandvaux, John Hiscott

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 370 KB

english, 2002

58

Activation of the ubiquitin proteolytic system in murine acquired immunodeficiency syndrome affects IκBα turnover

Rita Crinelli, Marzia Bianchi, Lucia Gentilini, Mauro Magnani, John Hiscott

Journal:

Year:

1999

Language:

english

File:

PDF, 608 KB

english, 1999

59

HTLV-1 HBZ protein inhibits IRF3-mediated innate immune responses

Renée N Douville, Stéphanie Olière, Patrick L Green, Rongtuan Lin, John Hiscott

Journal:

Year:

2011

Language:

english

File:

PDF, 79 KB

english, 2011

60

Sequence elements downstream of the human immunodeficiency virus type 1 long terminal repeat are required for efficient viral gene transcription

Chen Liang, Xuguang Li, Yudong Quan, Michael Laughrea, Lawrence Kleiman, John Hiscott, Mark A. Wainberg

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 419 KB

english, 1997

61

Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription

Pierre Morin, José Bragança, Marie-Thérèse Bandu, Rongtuan Lin, John Hiscott, Janine Doly, Ahmet Civas

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 388 KB

english, 2002

62

Molecular mechanisms of interferon beta gene induction

John Hiscott, Hannah Nguyen, Rongtuan Lin

Journal:

Seminars in Virology

Year:

1995

Language:

english

File:

PDF, 492 KB

english, 1995

63

Modulation of interferon gene transcription by positive and negative cellular factors

Steven Xanthoudakis, John Hiscott

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 701 KB

english, 1988

64

UV cross-linking of distinct proteins to the PRDII domain of the interferon-β promoter

Steven Xanthoudakis, John Hiscott

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 2.42 MB

english, 1990

65

Biological and biochemical inhibitors of the NF-κB/Rel proteins and cytokine synthesis

Pierre Beauparlant, John Hiscott

Journal:

Cytokine & Growth Factor Reviews

Year:

1996

Language:

english

File:

PDF, 1.55 MB

english, 1996

66

Cytokines

John Hiscott, Carl Ware

Journal:

Current Opinion in Immunology

Year:

2011

Language:

english

File:

PDF, 125 KB

english, 2011

67

Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter

S Mehdi Belgnaoui, Suzanne Paz, John Hiscott

Journal:

Current Opinion in Immunology

Year:

2011

Language:

english

File:

PDF, 1.25 MB

english, 2011

68

10 X-linked inhibitor of apoptosis protein inhibits RIG-I signalling pathway

Peyman Nakhaei, Thibault Mesplède, Qiang Sun, Simon Leveillé, Robert G. Korneluk, John Hiscott

Journal:

Year:

2008

Language:

english

File:

PDF, 47 KB

english, 2008

69

175 Opposite transcriptional effects of Interferon Regulatory Factor-3 on differential human interferon-A gene expresssion

Pierre Génin, Rongtuan Lin, John Hiscott, Ahmet Civas

Journal:

Year:

2008

Language:

english

File:

PDF, 46 KB

english, 2008

70

199 Targeting the apoptotic pathway with BCL-2 inhibitors sensitizes primary chronic lymphocytic leukemia to VSV-induced oncolysis

Vanessa F. Tumilasci, Stephanie Oliere, John Bell, John Hiscott

Journal:

Year:

2008

Language:

english

File:

PDF, 47 KB

english, 2008

71

213 Cell cycle and translational requirements for VSV oncolysis in primary CD4+ T-Lymphocytes

Stephanie Oliere, Vanessa Tumilasci, David Stojdl, Nahum Sonenberg, John Bell, John Hiscott

Journal:

Year:

2008

Language:

english

File:

PDF, 49 KB

english, 2008

72

355 Triad3A E3 ligase negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation

Peyman Nakhaei, Thibault Mesplede, Qiang Sun, Mayra Solis, Long Yang, Rongtuan Lin, Tsung-Hsien Chuang, Carl F. Ware, John Hiscott

Journal:

Year:

2008

Language:

english

File:

PDF, 44 KB

english, 2008

73

261 Activation of TLR-independent signaling pathway by HIV-1 in primary human macrophages

Mayra Solis, Thibault Mesplede, Peyman Nakhaei, John Hiscott

Journal:

Year:

2008

Language:

english

File:

PDF, 40 KB

english, 2008

74

291 Polo-like kinase 1 (PLK1) and protein kinase IKKε, two markers of cancer, down-regulate IFN induction by MAVS

Damien Vitour, Stéphanie Dabo, Malek Ahmadi Pour, Myriam Vilasco, Pierre-Olivier Vidalain, Yves Jacob, Pascal Pineau, Frédéric Tangy, John Hiscott, Eliane F. Meurs

Journal:

Year:

2008

Language:

english

File:

PDF, 124 KB

english, 2008

75

367 Ubiquitin-regulated recruitment of IKKε to MAVS interferon signaling adapter

Suzanne Paz, Myriam Vilasco, Meztli Arguello, Qiang Sun, Judith Lacoste, Rongtuan Lin, Eliane F. Meurs, John Hiscott

Journal:

Year:

2008

Language:

english

File:

PDF, 51 KB

english, 2008

76

322 Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis

Thi Lien-Anh Nguyên, Hesham Abdelbary, Meztli Arguello, Simon Leveille, John C. Bell, John Hiscott

Journal:

Year:

2008

Language:

english

File:

PDF, 119 KB

english, 2008

77

345 Gentically engineered oncolytic vesicular stomatitis virus to stimulate anti-tumor immune response

Simon Leveille, John Hiscott

Journal:

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

78

Regulation of innate immunity and inflammation by the mitotic kinase PLK1 through inhibition of IKKε activity

Stéphanie Dabo, Malek Ahmadi Pour, Damien Vitour, Olivera Grubisha, Myriam Vilasco, Pierre-Olivier Vidalain, Yves Jacob, Frédéric Tangy, John Hiscott, Eliane F. Meurs

Journal:

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

79

HTLV-1 evades type I IFN signaling by inducing the suppressor of cytokine signaling: “ SOCS-1”

Stephanie Oliere, Meztli Arguello, Thi Lien-AnhNguyen, Edouardo Hernandez, Agnes Lezin, John Hiscott

Journal:

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

80

Polo-like kinase 1 (PLK1) regulates IFN induction by MAVS

Damien Vitour, Stéphanie Dabo, Malek Ahmadi Pour, Myriam Vilasco, Pierre-Olivier Vidalain, Yves Jacob, Mariana Mezel-Lemoine, Suzanne Paz, Meztli Arguello, Rongtuan Lin, Frédéric Tangy, John Hiscott,

Journal:

Year:

2009

Language:

english

File:

PDF, 47 KB

english, 2009

81

Activation of the RIG-I signaling pathway inhibits HIV-1 replication

Mayra Solis, Peyman Nakhaei, John Hiscott

Journal:

Year:

2009

Language:

english

File:

PDF, 47 KB

english, 2009

82

The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation

Peyman Nakhaei, Thibault Mesplede, Mayra Solis, Qiang Sun, Tiejun Zhao, Long Yang, Tsung-Hsien Chuang, Carl F. Ware, Rongtuan Lin, John Hiscott

Journal:

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

83

Opposite effects of interferon regulatory factors 3 and 7 on differential modification of histone H3 associated to human interferon-A gene promoters

Pierre Génin, John Hiscott, Ahmet Civas

Journal:

Year:

2009

Language:

english

File:

PDF, 45 KB

english, 2009

84

The interface between the innate interferon response and expression of host retroviral restriction factors

Renée N. Douville, John Hiscott

Journal:

Year:

2010

Language:

english

File:

PDF, 690 KB

english, 2010

85

CS2-1 RIG-I like receptors: sensing and responding to RNA virus infection

John Hiscott, Peyman Nakhaei, Suzanne Paz, Myriam Vilasco, Delphine Goubau, Zheng-Yun Xu, Eliane F. Meurs, Rongtuan Lin

Journal:

Year:

2010

Language:

english

File:

PDF, 135 KB

english, 2010

86

PS2-49 Natural RNA agonists of RIG-I trigger a robust antiviral response that inhibits influenza infection

Zheng-Yun Xu, Meztli Arguello, Marieline Goulet, John Hiscott, Rongtuan Lin

Journal:

Year:

2010

Language:

english

File:

PDF, 55 KB

english, 2010

87

PS1-031. Characterization of the host antiviral response to HTLV-1 infection of plasmacytoid dendritic cells

Alexandre Sze, Renee Douville, Stephanie Olière, John Hiscott

Journal:

Year:

2011

Language:

english

File:

PDF, 133 KB

english, 2011

88

PS2-026. Virus derived 5’pppRNA agonists trigger a RIG-I dependent antiviral response that inhibits H1N1 influenza infection

Zheng-Yun Xu, Suzanne Paz, Marieline Goulet, Meztli Arguello, Rongtuan Lin, John Hiscott

Journal:

Year:

2011

Language:

english

File:

PDF, 45 KB

english, 2011

89

PS2-087 Targeting the apoptotic and autophagic pathway to augment oncolytic virotherapy of chronic lymphocytic leukemia

Sara Samuel, Stephanie Richards, Julien VanGrevenynghe, Stephanie Luco, April Shamy, Guillermo Abesada, John Hiscott

Journal:

Year:

2011

Language:

english

File:

PDF, 38 KB

english, 2011

90

CS04-2. Linear ubiquitination of nemo inhibits rig-i mediated signalling by disrupting the mavs-traf3 interaction

Sidi Mehdi Belgnaoui, Rongtuan Lin, John Hiscott

Journal:

Year:

2011

Language:

english

File:

PDF, 134 KB

english, 2011

91

CS13-6. Identification of NF-κB genes that contribute to reversible stimulation of VSV oncolysis by histone deacetylase inhibitors (HDIs)

Laura Shulak, Laura Shulak, Thomas Di Lenardo, Thi-Lien Anh Nguyen, John Hiscott

Journal:

Year:

2011

Language:

english

File:

PDF, 45 KB

english, 2011

92

CS09-7. Cross-talk between RIG-I dependent antiviral signalling and apoptosis

John Hiscott, Suzanne Paz, Peyman Nakhaei

Journal:

Year:

2011

Language:

english

File:

PDF, 38 KB

english, 2011

93

Introduction

Journal:

Cytokine & Growth Factor Reviews

Year:

2007

Language:

english

File:

PDF, 72 KB

english, 2007

94

Introduction

Journal:

Cytokine & Growth Factor Reviews

Year:

2009

Language:

english

File:

PDF, 66 KB

english, 2009

95

Modulation of innate immune responses during human T-cell leukemia virus (HTLV-1) pathogenesis

Stéphanie Olière, Renée Douville, Alexandre Sze, S. Mehdi Belgnaoui, John Hiscott

Journal:

Cytokine & Growth Factor Reviews

Year:

2011

Language:

english

File:

PDF, 1.48 MB

english, 2011

96

Oncolytic viruses and histone deacetylase inhibitors—A multi-pronged strategy to target tumor cells

Thi Lien-Anh Nguyen, Marnie Goodwin Wilson, John Hiscott

Journal:

Cytokine & Growth Factor Reviews

Year:

2010

Language:

english

File:

PDF, 225 KB

english, 2010

97

The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy

Yu Lei, Haitao Wen, Yanbao Yu, Debra J. Taxman, Lu Zhang, Douglas G. Widman, Karen V. Swanson, Kwun-Wah Wen, Blossom Damania, Chris B. Moore, Patrick M. Giguère, David P. Siderovski, John Hiscott, Bab

Journal:

Year:

2012

Language:

english

File:

PDF, 2.08 MB

english, 2012

98

Cell-specific Regulation of TRBP1 Promoter by NF-Y Transcription Factor in Lymphocytes and Astrocytes

Sylvie Bannwarth, Sébastien Lainé, Aïcha Daher, Nathalie Grandvaux, Guerline Clerzius, Andréa C. LeBlanc, John Hiscott, Anne Gatignol

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 609 KB

english, 2006

99

MasterCARD: a priceless link to innate immunity

John Hiscott, Rongtuan Lin, Peyman Nakhaei, Suzanne Paz

Journal:

Trends in Molecular Medicine

Year:

2006

Language:

english

File:

PDF, 798 KB

english, 2006

100

RIG-I-like receptors: Sensing and responding to RNA virus infection

Peyman Nakhaei, Pierre Genin, Ahmet Civas, John Hiscott

Journal:

Seminars in Immunology

Year:

2009

Language:

english

File:

PDF, 548 KB

english, 2009