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51

Extended longevity mechanisms in short-lived progeroid mice: Identification of a preservative stress response associated with successful aging

Marieke van de Ven, Jaan-Olle Andressoo, Valerie B. Holcomb, Paul Hasty, Yousin Suh, Harry van Steeg, George A. Garinis, Jan H.J. Hoeijmakers, James R. Mitchell

Journal:

Mechanisms of Ageing and Development

Year:

2007

Language:

english

File:

PDF, 190 KB

english, 2007

52

Genome maintenance mechanisms are critical for preventing cancer as well as other aging-associated diseases

Jan H.J. Hoeijmakers

Journal:

Mechanisms of Ageing and Development

Year:

2007

Language:

english

File:

PDF, 97 KB

english, 2007

53

Accelerated loss of hearing and vision in the DNA-repair deficient Ercc1δ/− mouse

Marcella Spoor, A. Paul Nagtegaal, Yanto Ridwan, Nils Z. Borgesius, Bart van Alphen, Ingrid van der Pluijm, Jan H.J. Hoeijmakers, Maarten A. Frens, J. Gerard G. Borst

Journal:

Mechanisms of Ageing and Development

Year:

2012

Language:

english

File:

PDF, 1.22 MB

english, 2012

54

Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice

Martijn E.T. Dollé, Rita A. Busuttil, Ana Maria Garcia, Susan Wijnhoven, Ellen van Drunen, Laura J. Niedernhofer, Gijsbertus van der Horst, Jan H.J. Hoeijmakers, Harry van Steeg, Jan Vijg

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2006

Language:

english

File:

PDF, 1.19 MB

english, 2006

55

MicroRNAs, the DNA damage response and cancer

Maikel D. Wouters, Dik C. van Gent, Jan H.J. Hoeijmakers, Joris Pothof

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2011

Language:

english

File:

PDF, 615 KB

english, 2011

56

The DNA repair-ubiquitin-associated HR23 proteins are constituents of neuronal inclusions in specific neurodegenerative disorders without hampering DNA repair

Steven Bergink, Lies-Anne Severijnen, Nils Wijgers, Kaoru Sugasawa, Humaira Yousaf, Johan M. Kros, John van Swieten, Ben A. Oostra, Jan H. Hoeijmakers, Wim Vermeulen, Rob Willemsen

Journal:

Neurobiology of Disease

Year:

2006

Language:

english

File:

PDF, 684 KB

english, 2006

57

The Structure of the Human ERCC1/XPF Interaction Domains Reveals a Complementary Role for the Two Proteins in Nucleotide Excision Repair

Konstantinos Tripsianes, Gert Folkers, Eiso AB, Devashish Das, Hanny Odijk, Nicolaas G.J. Jaspers, Jan H.J. Hoeijmakers, Robert Kaptein, Rolf Boelens

Journal:

Year:

2005

Language:

english

File:

PDF, 705 KB

english, 2005

58

The Structure of the XPF-ssDNA Complex Underscores the Distinct Roles of the XPF and ERCC1 Helix- Hairpin-Helix Domains in ss/ds DNA Recognition

Devashish Das, Gert E. Folkers, Marc van Dijk, Nicolaas G.J. Jaspers, Jan H.J. Hoeijmakers, Robert Kaptein, Rolf Boelens

Journal:

Year:

2012

Language:

english

File:

PDF, 884 KB

english, 2012

59

Age to survive: DNA damage and aging

Björn Schumacher, George A. Garinis, Jan H.J. Hoeijmakers

Journal:

Trends in Genetics

Year:

2008

Language:

english

File:

PDF, 529 KB

english, 2008

60

Divide and conquer: nucleotide excision repair battles cancer and ageing

James R Mitchell, Jan HJ Hoeijmakers, Laura J Niedernhofer

Journal:

Current Opinion in Cell Biology

Year:

2003

Language:

english

File:

PDF, 650 KB

english, 2003

61

Molecular mechanisms of DNA double-strand break repair

Roland Kanaar, Jan H.J Hoeijmakers, Dik C van Gent

Journal:

Trends in Cell Biology

Year:

1998

Language:

english

File:

PDF, 192 KB

english, 1998

62

A link between the accumulation of DNA damage and loss of multi-potency of human mesenchymal stromal cells

Hugo Alves, Ursula Munoz-Najar, Jan De Wit, Auke J. S. Renard, Jan H. J. Hoeijmakers, John M. Sedivy, Clemens Van Blitterswijk, Jan De Boer

Journal:

Journal of Cellular and Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 832 KB

english, 2010

63

Plasmodium falciparum centromeres display a unique epigenetic makeup and cluster prior to and during schizogony

Wieteke A. M. Hoeijmakers, Christian Flueck, Kees-Jan Françoijs, Arne H. Smits, Johanna Wetzel, Jennifer C. Volz, Alan F. Cowman, Till Voss, Hendrik G. Stunnenberg, Richárd Bártfai

Journal:

Cellular Microbiology

Year:

2012

Language:

english

File:

PDF, 975 KB

english, 2012

64

Linear amplification for deep sequencing

Hoeijmakers, Wieteke A M, Bártfai, Richárd, Françoijs, Kees-Jan, Stunnenberg, Hendrik G

Journal:

Bioentrepreneur

Year:

2011

Language:

english

File:

PDF, 771 KB

english, 2011

65

Genetic Correction of DNA Repair-Deficient/Cancer-Prone Xeroderma Pigmentosum Group C Keratinocytes

Arnaudeau-Bégard, Catherine, Brellier, Florence, Chevallier-Lagente, Odile, Hoeijmakers, Jan, Bernerd, Françoise, Sarasin, Alain, Magnaldo, Thierry

Journal:

Human Gene Therapy

Year:

2003

Language:

english

File:

PDF, 788 KB

english, 2003

66

Postmeiotic Transcription of X and Y Chromosomal Genes during Spermatogenesis in the Mouse

Peter J.M. Hendriksen, Jos W. Hoogerbrugge, Axel P.N. Themmen, Marcel H.M. Koken, Jan H.J. Hoeijmakers, Ben A. Oostra, Tette van der Lende, J.Anton Grootegoed

Journal:

Developmental Biology

Year:

1995

File:

PDF, 302 KB

1995

67

Expression of the Ubiquitin-Conjugating DNA Repair Enzymes HHR6A and B Suggests a Role in Spermatogenesis and Chromatin Modification

Marcel H.M. Koken, Jos W. Hoogerbrugge, Iris Jaspers-Dekker, Jan de Wit, Rob Willemsen, Henk P. Roest, J.Anton Grootegoed, Jan H.J. Hoeijmakers

Journal:

Developmental Biology

Year:

1996

Language:

english

File:

PDF, 363 KB

english, 1996

68

Histone Ubiquitination and Chromatin Remodeling in Mouse Spermatogenesis

Willy M Baarends, Jos W Hoogerbrugge, Henk P Roest, Marja Ooms, Jan Vreeburg, Jan H.J Hoeijmakers, J.Anton Grootegoed

Journal:

Developmental Biology

Year:

1999

Language:

english

File:

PDF, 616 KB

english, 1999

69

Cloning, Comparative Mapping, and RNA Expression of the Mouse Homologues of theSaccharomyces cerevisiaeNucleotide Excision Repair GeneRAD23

Peter J. van der Spek, Cécile E. Visser, Fumio Hanaoka, Bep Smit, Anne Hagemeijer, Dirk Bootsma, Jan H.J. Hoeijmakers

Journal:

Year:

1996

Language:

english

File:

PDF, 284 KB

english, 1996

70

Sequence Conservation of therad21 Schizosaccharomyces pombeDNA Double-Strand Break Repair Gene in Human and Mouse

Michael J. McKay, Christine Troelstra, Peter van der, Roland Kanaar, Bep Smit, Anne Hagemeijer, Dirk Bootsma, Jan H.J. Hoeijmakers

Journal:

Year:

1996

Language:

english

File:

PDF, 632 KB

english, 1996

71

A Human and Mouse Homolog of theSchizosaccharomyces pombe rad1+Cell Cycle Checkpoint Control Gene

Hans A.R. Bluyssen, Roselinde I. van Os, Nicole C. Naus, Iris Jaspers, Jan H.J. Hoeijmakers, Annelies de Klein

Journal:

Year:

1998

Language:

english

File:

PDF, 2.99 MB

english, 1998

72

Human and Mouse Homologs of theSchizosaccharomyces pombe rad17+Cell Cycle Checkpoint Control Gene

Hans A.R. Bluyssen, Nicole C. Naus, Roselinde I. van Os, Iris Jaspers, Jan H.J. Hoeijmakers, Annelies de Klein

Journal:

Year:

1999

Language:

english

File:

PDF, 506 KB

english, 1999

73

Characterization of mRAD18Sc, a Mouse Homolog of the Yeast Postreplication Repair Gene RAD18

Roald van der Laan, Henk P. Roest, Jos W. Hoogerbrugge, Elisabeth M.E. Smit, Rosalyn Slater, Willy M. Baarends, Jan H.J. Hoeijmakers, J.Anton Grootegoed

Journal:

Year:

2000

Language:

english

File:

PDF, 686 KB

english, 2000

74

Differences between rodent and human cell lines in the amount of integrated DNA after transfection

Jan H.J. Hoeijmakers, Hanny Odijk, Andries Westerveld

Journal:

Experimental Cell Research

Year:

1987

Language:

english

File:

PDF, 1.64 MB

english, 1987

75

Fanconi Anemia (Cross)linked to DNA Repair

Laura J. Niedernhofer, Astrid S. Lalai, Jan H.J. Hoeijmakers

Journal:

Year:

2005

Language:

english

File:

PDF, 736 KB

english, 2005

76

Relative levels of the two mammalian Rad23 homologs determine composition and stability of the xeroderma pigmentosum group C protein complex

Yuki Okuda, Ryotaro Nishi, Jessica M.Y. Ng, Wim Vermeulen, Gijsbertus T.J. van der Horst, Toshio Mori, Jan H.J. Hoeijmakers, Fumio Hanaoka, Kaoru Sugasawa

Journal:

Year:

2004

Language:

english

File:

PDF, 401 KB

english, 2004

77

Accelerated aging pathology in ad libitum fed XpdTTD mice is accompanied by features suggestive of caloric restriction

Susan W.P. Wijnhoven, Rudolf B. Beems, Marianne Roodbergen, Jolanda van den Berg, Paul H.M. Lohman, Karin Diderich, Gijsbertus T.J. van der Horst, Jan Vijg, Jan H.J. Hoeijmakers, Harry van Steeg

Journal:

Year:

2005

Language:

english

File:

PDF, 1.97 MB

english, 2005

78

Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase ι

Stella A. Martomo, William W. Yang, Alexandra Vaisman, Alex Maas, Masayuki Yokoi, Jan H. Hoeijmakers, Fumio Hanaoka, Roger Woodgate, Patricia J. Gearhart

Journal:

Year:

2006

Language:

english

File:

PDF, 374 KB

english, 2006

79

Dietary Restriction Modifies Certain Aspects of the Postoperative Acute Phase Response

Tessa M. van Ginhoven, Willem A. Dik, James R. Mitchell, Marja A. Smits-te Nijenhuis, Conny van Holten-Neelen, Herbert Hooijkaas, Jan H.J. Hoeijmakers, Ron W.F. de Bruin, Jan N.M. IJzermans

Journal:

Journal of Surgical Research

Year:

2011

Language:

english

File:

PDF, 241 KB

english, 2011

80

Sealing the gap between nuclear DNA damage and longevity

Björn Schumacher, Jan H. Hoeijmakers, George A. Garinis

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 446 KB

english, 2009

81

Erratum to “Sealing the gap between nuclear DNA damage and longevity” [Mol. Cell. Endocrinol. 299 (2009) 112–117]

Björn Schumacher, Jan H. Hoeijmakers, George A. Garinis

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 68 KB

english, 2009

82

Disruption of Mouse RAD54 Reduces Ionizing Radiation Resistance and Homologous Recombination

Jeroen Essers, Rudolf W Hendriks, Sigrid M.A Swagemakers, Christine Troelstra, Jan de Wit, Dirk Bootsma, Jan H.J Hoeijmakers, Roland Kanaar

Journal:

Year:

1997

Language:

english

File:

PDF, 195 KB

english, 1997

83

Knockout mouse model and gametogenic failure

J.Anton Grootegoed, Willy M Baarends, Henk P Roest, Jan H.J Hoeijmakers

Journal:

Molecular and Cellular Endocrinology

Year:

1998

Language:

english

File:

PDF, 85 KB

english, 1998

84

TFIIH: a key component in multiple DNA transactions

Jan H.J. Hoeijmakers, Jean-Marc Egly, Wim Vermeulen

Journal:

Current Opinion in Genetics & Development

Year:

1996

Language:

english

File:

PDF, 3.21 MB

english, 1996

85

Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair

Kaoru Sugasawa, Jessica M.Y Ng, Chikahide Masutani, Shigenori Iwai, Peter J van der Spek, André P.M Eker, Fumio Hanaoka, Dirk Bootsma, Jan H.J Hoeijmakers

Journal:

Year:

1998

Language:

english

File:

PDF, 438 KB

english, 1998

86

A Mouse Model for the Basal Transcription/DNA Repair Syndrome Trichothiodystrophy

Jan de Boer, Jan de Wit, Harry van Steeg, Rob J.W. Berg, Hans Morreau, Pim Visser, Alan R. Lehmann, Marinus Duran, Jane H.J. Hoeijmakers, Geert Weeda

Journal:

Year:

1998

Language:

english

File:

PDF, 318 KB

english, 1998

87

Sequential Assembly of the Nucleotide Excision Repair Factors In Vivo

Marcel Volker, Martijn J Moné, Parimal Karmakar, Anneke van Hoffen, Wouter Schul, Wim Vermeulen, Jan H.J Hoeijmakers, Roel van Driel, Albert A van Zeeland, Leon H.F Mullenders

Journal:

Year:

2001

Language:

english

File:

PDF, 547 KB

english, 2001

88

Rapid Switching of TFIIH between RNA Polymerase I and II Transcription and DNA Repair In Vivo

Deborah Hoogstraten, Alex L Nigg, Helen Heath, Leon H.F Mullenders, Roel van Driel, Jan H.J Hoeijmakers, Wim Vermeulen, Adriaan B Houtsmuller

Journal:

Year:

2002

Language:

english

File:

PDF, 628 KB

english, 2002

89

ERCC1/XPF Removes the 3′ Overhang from Uncapped Telomeres and Represses Formation of Telomeric DNA-Containing Double Minute Chromosomes

Xu-Dong Zhu, Laura Niedernhofer, Bernhard Kuster, Matthias Mann, Jan H.J Hoeijmakers, Titia de Lange

Journal:

Year:

2003

Language:

english

File:

PDF, 634 KB

english, 2003

90

Analysis of mouse Rad54 expression and its implications for homologous recombination

Jeroen Essers, Rudi W. Hendriks, Joanna Wesoly, Cecile E.M.T. Beerens, Bep Smit, Jan H.J. Hoeijmakers, Claire Wyman, Mies L.G. Dronkert, Roland Kanaar

Journal:

Year:

2002

Language:

english

File:

PDF, 342 KB

english, 2002

91

UVB radiation-induced cancer predisposition in Cockayne syndrome group A (Csa) mutant mice

Gijsbertus T.J van der Horst, Lisiane Meira, Theo G.M.F Gorgels, Jan de Wit, Susana Velasco-Miguel, James A Richardson, Yvonne Kamp, Maaike P.G Vreeswijk, Bep Smit, Dirk Bootsma, Jan H.J Hoeijmakers,

Journal:

Year:

2002

Language:

english

File:

PDF, 3.19 MB

english, 2002

92

Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice

Harm de Waard, Jan de Wit, Theo G.M.F Gorgels, Gerard van den Aardweg, Jaan-Olle Andressoo, Marcel Vermeij, Harry van Steeg, Jan H.J Hoeijmakers, Gijsbertus T.J van der Horst

Journal:

Year:

2003

Language:

english

File:

PDF, 313 KB

english, 2003

93

Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways

Nicolaas G.J Jaspers, Anja Raams, Michael J Kelner, Jessica M.Y Ng, Yukiko M Yamashita, Shiunichi Takeda, Trevor C McMorris, Jan H.J Hoeijmakers

Journal:

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

94

DNA bending by the human damage recognition complex XPC–HR23B

Ana Janićijević, Kaoru Sugasawa, Yuichiro Shimizu, Fumio Hanaoka, Nils Wijgers, Miodrag Djurica, Jan H.J. Hoeijmakers, Claire Wyman

Journal:

Year:

2003

Language:

english

File:

PDF, 384 KB

english, 2003

95

Cancer from the outside, aging from the inside: Mouse models to study the consequences of defective nucleotide excision repair

Jan de Boer, Jan H.J. Hoeijmakers

Journal:

Year:

1999

Language:

english

File:

PDF, 330 KB

english, 1999

96

Mutations in DDHD2, Encoding an Intracellular Phospholipase A1, Cause a Recessive Form of Complex Hereditary Spastic Paraplegia

Janneke H.M. Schuurs-Hoeijmakers, Michael T. Geraghty, Erik-Jan Kamsteeg, Salma Ben-Salem, Susanne T. de Bot, Bonnie Nijhof, Ilse I.G.M. van de Vondervoort, Marinette van der Graaf, Anna Castells Noba

Journal:

The American Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 764 KB

english, 2012

97

Effects of compound heterozygosity at the Xpd locus on cancer and ageing in mouse models

van de Ven, Marieke, Andressoo, Jaan-Olle, van der Horst, Gijsbertus T.J., Hoeijmakers, Jan H.J., Mitchell, James R.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.24 MB

english, 2012

98

ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes

Christine Troelstra, Alain van Gool, Jan de Wit, Wim Vermeulen, Dirk Bootsma, Jan H.J. Hoeijmakers

Journal:

Year:

1992

Language:

english

File:

PDF, 3.72 MB

english, 1992

99

A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome

Geert Weeda, Reinier C.A. van Ham, Wim Vermeulen, Dirk Bootsma, Alex J. van der Eb, Jan H.J. Hoeijmakers

Journal:

Year:

1990

Language:

english

File:

PDF, 2.37 MB

english, 1990

100

The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor

Richard Roy, Jörg P. Adamczewski, Thierry Seroz, Wim Vermeulen, Jean-Pierre Tassan, Laurent Schaeffer, Erich A. Nigg, Jan H.J. Hoeijmakers, Jean-Marc Egly

Journal:

Year:

1994

Language:

english

File:

PDF, 2.40 MB

english, 1994

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