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51

Drug Metabolism and Pharmacokinetics Quick Guide Volume 24 || || Front_matter

Khojasteh, Siamak Cyrus, Wong, Harvey, Hop, Cornelis E.C.A.

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

52

Drug Metabolism and Pharmacokinetics Quick Guide Volume 5b || Prediction of Human Pharmacokinetics

Khojasteh, Siamak Cyrus, Wong, Harvey, Hop, Cornelis E.C.A.

Year:

2011

Language:

english

File:

PDF, 421 KB

english, 2011

53

Drug Metabolism and Pharmacokinetics Quick Guide Volume 5b || Approved Drugs

Khojasteh, Siamak Cyrus, Wong, Harvey, Hop, Cornelis E.C.A.

Year:

2011

Language:

english

File:

PDF, 129 KB

english, 2011

54

Drug Metabolism and Pharmacokinetics Quick Guide Volume 5b || Chemical Nomenclature

Khojasteh, Siamak Cyrus, Wong, Harvey, Hop, Cornelis E.C.A.

Year:

2011

Language:

english

File:

PDF, 283 KB

english, 2011

55

Drug Metabolism and Pharmacokinetics Quick Guide Volume 5b || In Silico ADME Tools

Khojasteh, Siamak Cyrus, Wong, Harvey, Hop, Cornelis E.C.A.

Year:

2011

Language:

english

File:

PDF, 199 KB

english, 2011

56

Drug Metabolism and Pharmacokinetics Quick Guide Volume 5b || Biotransformation and Bioactivation

Khojasteh, Siamak Cyrus, Wong, Harvey, Hop, Cornelis E.C.A.

Year:

2011

Language:

english

File:

PDF, 782 KB

english, 2011

57

Drug Metabolism and Pharmacokinetics Quick Guide Volume 5b || Advances in Bioanalysis as It Relates to ADME

Khojasteh, Siamak Cyrus, Wong, Harvey, Hop, Cornelis E.C.A.

Year:

2011

Language:

english

File:

PDF, 282 KB

english, 2011

58

Validation and application of a liquid chromatography-tandem mass spectrometric method for the determination of GDC-0152 in human plasma using solid-phase extraction

Young G. Shin, Steve A. Jones, Stan C. Murakami, Nageshwar Budha, Joseph Ware, Harvey Wong, Michael H. Buonarati, Brian Dean, Cornelis E. C. A. Hop

Journal:

Biomedical Chromatography

Year:

2012

Language:

english

File:

PDF, 356 KB

english, 2012

59

Validation and application of a liquid chromatography–tandem mass spectrometric method for the determination of GDC-0834 and its metabolite in human plasma using semi-automated 96-well protein precipitation

Young G. Shin, Steve A. Jones, Stan C. Murakami, Lichuan Liu, Harvey Wong, Michael H. Buonarati, Cornelis E. C. A. Hop

Journal:

Biomedical Chromatography

Year:

2012

Language:

english

File:

PDF, 280 KB

english, 2012

60

Umbilical cord separation in twins

Anne Marie Oudesluys-Murphy, Willem Hop, Cornelis de Groot

Journal:

Early Human Development

Year:

1989

Language:

english

File:

PDF, 297 KB

english, 1989

61

Metabolic activation of the nontricyclic antidepressant trazodone to electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4

Amit S. Kalgutkar, Kirk R. Henne, Mary E. Lame, Alfin D.N. Vaz, Claire Collin, John R. Soglia, Sabrina X. Zhao, Cornelis E.C.A. Hop

Journal:

Chemico-Biological Interactions

Year:

2005

Language:

english

File:

PDF, 461 KB

english, 2005

62

Validation and application of a liquid chromatography–tandem mass spectrometric method for the determination of G-856 (Cur-61414) in human plasma using semi-automated solid phase extraction

Young G. Shin, Stan C. Murakami, Michael H. Buonarati, Brian Dean, Cornelis E.C.A. Hop

Journal:

Journal of Chromatography B

Year:

2012

Language:

english

File:

PDF, 813 KB

english, 2012

63

High-throughput liquid chromatography/mass spectrometry method for the quantitation of small molecules using accurate mass technologies in supporting discovery drug screening

Ding, Xiao, Ghobarah, Hesham, Zhang, Xiaolin, Jaochico, Allan, Liu, Xingrong, Deshmukh, Gauri, Liederer, Bianca M., Hop, Cornelis E. C. A., Dean, Brian

Journal:

Rapid Communications in Mass Spectrometry

Year:

2013

Language:

english

File:

PDF, 813 KB

english, 2013

64

Validation and application of a liquid chromatography–tandem mass spectrometric method for the determination of GDC-0879 and its metabolite in dog plasma using solid phase extraction

Bilin Chou, Ryan S. Adler, Min Meng, Shaundel Percey, Brian Dean, Cornelis E.C.A. Hop, Young G. Shin

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2012

Language:

english

File:

PDF, 752 KB

english, 2012

65

A randomized trial of cryo stripping versus conventional stripping of the great saphenous vein

Taco M.A.L. Klem, J. Marco Schnater, P. Ronald Schütte, Wim Hop, Arie C. van der Ham, Cornelis H.A. Wittens

Journal:

Journal of Vascular Surgery

Year:

2009

Language:

english

File:

PDF, 290 KB

english, 2009

66

Burns to the head and neck: Epidemiology and predictors of surgery

Hoogewerf, Cornelis J., van Baar, Margriet E., Hop, M. Jenda, Bloemen, Monica C.T., Middelkoop, Esther, Nieuwenhuis, Marianne K.

Journal:

Year:

2013

Language:

english

File:

PDF, 372 KB

english, 2013

67

Novel Mechanism for Dehalogenation and Glutathione Conjugation of Dihalogenated Anilines in Human Liver Microsomes: Evidence for ipso Glutathione Addition

Zhang, Chenghong, Kenny, Jane R., Le, Hoa, Deese, Alan, Ford, Kevin A., Lightning, Luke K., Fan, Peter W., Driscoll, James P., Halladay, Jason S., Hop, Cornelis E. C. A., Khojasteh, S. Cyrus

Journal:

Chemical Research in Toxicology

Year:

2011

Language:

english

File:

PDF, 1.19 MB

english, 2011

68

Drug Metabolism and Pharmacokinetics Quick Guide || ADME Properties and Their Dependence on Physicochemical Properties

Khojasteh, Siamak Cyrus, Wong, Harvey, Hop, Cornelis E.C.A.

Year:

2011

Language:

english

File:

PDF, 327 KB

english, 2011

69

[HNCO].+, [HCNO].+, and [CNOH].+ and their neutral counterparts studied by mass spectrometry

Hop, Cornelis E. C. A., Van den Berg, Klaas Jan, Holmes, John L., Terlouw, Johan K.

Journal:

Journal of the American Chemical Society

Year:

1989

Language:

english

File:

PDF, 477 KB

english, 1989

70

A Semiquantitative Method for the Determination of Reactive Metabolite Conjugate Levels in Vitro Utilizing Liquid Chromatography−Tandem Mass Spectrometry and Novel Quaternary Ammonium Glutathione Analogues

Soglia, John R., Contillo, Leonard G., Kalgutkar, Amit S., Zhao, Sabrina, Hop, Cornelis E. C. A., Boyd, James G., Cole, Mark J.

Journal:

Chemical Research in Toxicology

Year:

2006

Language:

english

File:

PDF, 301 KB

english, 2006

71

Drug Metabolism and Pharmacokinetics Quick Guide ||

Khojasteh, Siamak Cyrus, Wong, Harvey, Hop, Cornelis E.C.A.

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

72

Dose-dependent exposure and metabolism of GNE-892, a β-secretase inhibitor, in monkeys: contributions by P450, AO, and P-gp

Takahashi, Ryan, Ma, Shuguang, Yue, Qin, Kim-Kang, Heasook, Yi, Yijun, Lyssikatos, Joseph P., Regal, Kelly, Hunt, Kevin W., Kallan, Nicholas C., Siu, Michael, Hop, Cornelis E. C. A., Liu, Xingrong, Kh

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

73

Assessment of the Hepatic CYP Reductase Null Mouse Model and Its Potential Application in Drug Discovery

Boggs, Jason W., Hop, Cornelis E. C. A., McNamara, Erin, Deng, Yuzhong, Messick, Kirsten, West, Kristina, Choo, Edna F.

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 429 KB

english, 2014

74

Rational Use of Plasma Protein and Tissue Binding Data in Drug Design

Liu, Xingrong, Wright, Matthew, Hop, Cornelis E. C. A.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

75

H2Te2 Is Stable in the Gas Phase

Hop, Cornelis E. C. A., Medina, Marco A.

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 223 KB

english, 1994

76

Electrospray Mass Spectrometry of Borane Salts: Observation of High Molecular Weight Ion Clusters

Hop, Cornelis E. C. A., Saulys, Dovas A., Gaines, Donald F.

Journal:

Inorganic Chemistry

Year:

1995

Language:

english

File:

PDF, 272 KB

english, 1995

77

[Annual Reports in Medicinal Chemistry] Annual Reports in Medicinal Chemistry Volume 41 Volume 41 || Importance of Early Assessment of Bioactivation in Drug Discovery

Hop, Cornelis E.C.A.

Year:

2006

Language:

english

File:

PDF, 161 KB

english, 2006

78

The isomeric [C2H6O2].cntdot.+ hydrogen-bridged radical cations [CH2-O(H).cntdot..cntdot..cntdot.H.cntdot..cntdot..cntdot.O:CH2].cntdot.+, [CH3-O.cntdot..cntdot..cntdot.H.cntdot..cntdot..cntdot.O:CH2].cntdot.+, and [CH3-O(H).cntdot..cntdot..cntdot.H.cntdot..cntdot..cntdot.O:CH].cntdot.+: theory and experiment

Burgers, Peter C., Holmes, John L., Hop, Cornelis E. C. A., Postma, Ron, Ruttink, Paul J. A., Terlouw, Johan K.

Journal:

Journal of the American Chemical Society

Year:

1987

Language:

english

File:

PDF, 879 KB

english, 1987

79

Method for Internal Standard Introduction for Quantitative Analysis Using On-Line Solid-Phase Extraction LC−MS/MS

Alnouti, Yazen, Li, Ming, Kavetskaia, Olga, Bi, Honggang, Hop, Cornelis E. C. A., Gusev, Arkady I.

Journal:

Analytical Chemistry

Year:

2006

Language:

english

File:

PDF, 236 KB

english, 2006

80

For a series of methylindole analogs, reactive metabolite formation is a poor predictor of intrinsic cytotoxicity in human hepatocytes

Zhang, Chenghong, Ma, Shuguang, Delarosa, Erlie Marie, Tay, Suzanne, Sodhi, Jasleen, Musinipally, Vivek, Chang, Patricia, Pai, Rama, Halladay, Jason S., Misner, Dinah, Kenny, Jane R., Hop, Cornelis E.

Journal:

Toxicology Research

Year:

2014

Language:

english

File:

PDF, 572 KB

english, 2014

81

Radiolabeled mass-balance excretion and metabolism studies in laboratory animals: a commentary on why they are still necessary

White, Ronald E., Evans, David C., Hop, Cornelis E. C. A., Moore, David J., Prakash, Chandra, Surapaneni, Sekhar, Tse, Francis L. S.

Journal:

Year:

2013

Language:

english

File:

PDF, 632 KB

english, 2013

82

Franck-Condon Dominated Chemistry. Dissociations of Silicon-Centered Radicals Prepared by Femtosecond Reduction of Their Cations in the Gas Phase

Nguyen, Viet Q., Shaffer, Scott A., Turecek, Frantisek, Hop, Cornelis E. C. A.

Journal:

Journal of Physical Chemistry

Year:

1995

Language:

english

File:

PDF, 1.20 MB

english, 1995

83

Physiologically Based Pharmacokinetic Modeling as a Tool to Predict Drug Interactions for Antibody-Drug Conjugates

Chen, Yuan, Samineni, Divya, Mukadam, Sophie, Wong, Harvey, Shen, Ben-Quan, Lu, Dan, Girish, Sandhya, Hop, Cornelis, Jin, Jin Yan, Li, Chunze

Journal:

Clinical Pharmacokinetics

Year:

2015

Language:

english

File:

PDF, 818 KB

english, 2015

84

Costs of burn care: A systematic review

Hop, M. Jenda, Polinder, Suzanne, van der Vlies, Cornelis H., Middelkoop, Esther, van Baar, Margriet E.

Journal:

Wound Repair and Regeneration

Year:

2014

Language:

english

File:

PDF, 188 KB

english, 2014

85

Prediction of Drug Distribution in Subcutaneous Xenografts of Human Tumor Cell Lines and Healthy Tissues in Mouse: Application of the Tissue Composition-Based Model to Antineoplastic Drugs

Poulin, Patrick, Chen, Yung-Hsiang, Ding, Xiao, Gould, Stephen E., Hop, Cornelis Eca, Messick, Kirsten, Oeh, Jason, Liederer, Bianca M.

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 325 KB

english, 2015

86

Use of Nano-Electrospray for Metabolite Identification and QuantitativeAbsorption, Distribution, Metabolism and Excretion Studies

E.C.A. Hop, Cornelis

Journal:

Current Drug Metabolism

Year:

2006

Language:

english

File:

PDF, 149 KB

english, 2006

87

Measuring NAD + levels in mouse blood and tissue samples via a surrogate matrix approach using LC–MS/MS

Liang, Xiaorong, Yang, Lulu, Qin, Ann R, Ly, Justin, Liederer, Bianca M, Messick, Kirsten, Ma, Shuguang, Zak, Mark, Dragovich, Peter S, Dean, Brian J, Hop, Cornelis ECA, Deng, Yuzhong

Journal:

Year:

2014

Language:

english

File:

PDF, 1.27 MB

english, 2014

88

Franck-Condon Dominated Chemistry. Formation and Dissociations of Tetrahydroxyphosphoranyl Radicals Following Femtosecond Reduction of Their Cations in the Gas Phase

Turecek, Franticek, Gu, Ming, Hop, Cornelis E. C. A.

Journal:

Journal of Physical Chemistry

Year:

1995

Language:

english

File:

PDF, 1.99 MB

english, 1995

89

Inhibitory Properties of Trapping Agents: Glutathione, Potassium Cyanide, and Methoxylamine, Against Major Human Cytochrome P450 Isoforms

Zhang, Chenghong, Wong, Susan, Delarosa, Erlie, Kenny, Jane, Halladay, Jason, Hop, Cornelis, Khojasteh-Bakht, Siamak

Journal:

Drug Metabolism Letters

Year:

2009

Language:

english

File:

PDF, 123 KB

english, 2009

90

Do We Need to Optimize Plasma Protein and Tissue Binding in Drug Discovery?

Liu, Xingrong, Chen, Cuiping, E.C.A. Hop, Cornelis

Journal:

Current Topics in Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

91

Development of a Physiologically Based Pharmacokinetic Model for Itraconazole Pharmacokinetics and Drug–Drug Interaction Prediction

Chen, Yuan, Ma, Fang, Lu, Tong, Budha, Nageshwar, Jin, Jin Yan, Kenny, Jane R., Wong, Harvey, Hop, Cornelis E. C. A., Mao, Jialin

Journal:

Clinical Pharmacokinetics

Year:

2016

Language:

english

File:

PDF, 2.38 MB

english, 2016

92

Surrogate analyte approach for quantitation of endogenous NAD+ in human acidified blood samples using liquid chromatography coupled with electrospray ionization tandem mass spectrometry

Liu, Liling, Cui, Zhiyi, Deng, Yuzhong, Dean, Brian, Hop, Cornelis E.C.A., Liang, Xiaorong

Journal:

Journal of Chromatography B

Year:

2016

Language:

english

File:

PDF, 927 KB

english, 2016

93

Simultaneous determination of itraconazole, hydroxy itraconazole, keto itraconazole and N-desalkyl itraconazole concentration in human plasma using liquid chromatography with tandem mass spectrometry

Liang, Xiaorong, Van Parys, Michael, Ding, Xiao, Zeng, Ning, Bi, Luke, Dorshort, Drew, McKnight, Janine, Milanowski, Dennis, Mao, Jialin, Chen, Yuan, Ware, Joseph A, Dean, Brian, Hop, Cornelis E.C.A.,

Journal:

Journal of Chromatography B

Year:

2016

Language:

english

File:

PDF, 1.32 MB

english, 2016

94

Evaluation of Time Dependent Inhibition Assays for Marketed Oncology Drugs: Comparison of Human Hepatocytes and Liver Microsomes in the Presence and Absence of Human Plasma

Mao, Jialin, Tay, Suzanne, Khojasteh, Cyrus S., Chen, Yuan, Hop, Cornelis E. C. A., Kenny, Jane R.

Journal:

Pharmaceutical Research

Year:

2016

Language:

english

File:

PDF, 1.33 MB

english, 2016

95

Absorption, metabolism and excretion of cobimetinib, an oral MEK inhibitor, in rats and dogs

Takahashi, Ryan H., Ma, Shuguang, Yue, Qin, Kim-Kang, Heasook, Yi, Yijun, Ly, Justin, Boggs, Jason W., Fettes, Alec, McClory, Andrew, Deng, Yuzhong, Hop, Cornelis E. C. A., Khojasteh, S. Cyrus, Choo,

Journal:

Year:

2016

Language:

english

File:

PDF, 2.36 MB

english, 2016

96

A clinical drug–drug interaction study to evaluate the effect of a proton-pump inhibitor, a combined P-glycoprotein/cytochrome 450 enzyme (CYP)3A4 inhibitor, and a CYP2C9 inhibitor on the pharmacokinetics of vismodegib

Malhi, Vikram, Colburn, Dawn, Williams, Sarah J., Hop, Cornelis E. C. A., Dresser, Mark J., Chandra, Priya, Graham, Richard A.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 507 KB

english, 2016

97

Correlation of Tissue-Plasma Partition Coefficients Between Normal Tissues and Subcutaneous Xenografts of Human Tumor Cell Lines in Mouse as a Prediction Tool of Drug Penetration in Tumors

Poulin, Patrick, Hop, Cornelis Eca, Salphati, Laurent, Liederer, Bianca M.

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 1.32 MB

english, 2013

98

Tibial Quantitative Ultrasound Versus Whole-Body and Lumbar Spine DXA in a Dutch Pediatric and Adolescent Population

van Rijn, Rick R., van der Sluis, Inge M., Lequin, Maarten H., Robben, Simon G. F., de Muinck Keizer-Schrama, Sabine M. P. F., Hop, Wim C. J., van Kuijk, Cornelis

Journal:

Investigative Radiology

Year:

2000

Language:

english

File:

PDF, 65 KB

english, 2000

99

Finding Order Amid Chaos: In Vitro Challenges Working with Boronic Acid-Containing Compounds

Mulde, Teresa, Liang, Xiaorong, Zhang, Chenghong, Le, Hoa, Baumgardner, Matt, Ho, Quynh, Ubhayakar, Savita, Chen, Yuan, Cyrus Khojasteh, S., E.C.A. Hop, Cornelis, Fan, Peter

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 233 KB

english, 2015

100

Comparison of Metabolic Soft Spot Predictions of CYP3A4, CYP2C9 and CYP2D6 Substrates Using MetaSite and StarDrop

G. Shin, Young, Le, Hoa, Khojasteh, Cyrus, E.C.A. Hop, Cornelis

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011