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51

Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro

Worek, Franz, Seeger, Thomas, Goldsmith, Moshe, Ashani, Yacov, Leader, Haim, Sussman, Joel S., Tawfik, Dan, Thiermann, Horst, Wille, Timo

Journal:

Archives of Toxicology

Year:

2014

Language:

english

File:

PDF, 631 KB

english, 2014

52

In vitro kinetics of nerve agent degradation by fresh frozen plasma (FFP)

Wille, Timo, Thiermann, Horst, Worek, Franz

Journal:

Archives of Toxicology

Year:

2014

Language:

english

File:

PDF, 404 KB

english, 2014

53

Effectiveness of a substituted β-cyclodextrin to prevent cyclosarin toxicity in vivo

Worek, Franz, Seeger, Thomas, Zengerle, Michael, Kubik, Stefan, Thiermann, Horst, Wille, Timo

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 1.27 MB

english, 2014

54

Fourteenth International Medical Chemical Defence Conference 2013 “Translation of experimental research for improved treatment of chemical warfare agents”

Wille, Timo, Worek, Franz, Thiermann, Horst

Journal:

Chemico-Biological Interactions

Year:

2013

Language:

english

File:

PDF, 163 KB

english, 2013

55

Neuere Geschichte (1789-1870)

Review by: Fritz Valjavec, Günther Franz, Reinhardt Habel, Georg Franz-Willing, Horst Stuke, H. Kloss and J. Deér

Journal:

Historische Zeitschrift

Year:

1960

File:

PDF, 625 KB

1960

56

Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyrylcholinesterase

Horn, Gabriele, Wille, Timo, Musilek, Kamil, Kuca, Kamil, Thiermann, Horst, Worek, Franz

Journal:

Archives of Toxicology

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

57

Role of crystallins in ocular neuroprotection and axonal regeneration

Thanos, Solon, Böhm, Michael R.R., Meyer zu Hörste, Melissa, Prokosch-Willing, Verena, Hennig, Maren, Bauer, Dirk, Heiligenhaus, Arndt

Journal:

Progress in Retinal and Eye Research

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

58

Peptide conformations. 46. Conformational analysis of a superpotent cytoprotective cyclic somatostatin analog

Kessler, Horst., Bats, Jan Willem., Griesinger, Christian., Koll, Sylvie., Will, Martin., Wagner, Klaus.

Journal:

Journal of the American Chemical Society

Year:

1988

Language:

english

File:

PDF, 2.78 MB

english, 1988

59

Adaptation of a dynamic in vitro model with real-time determination of butyrylcholinesterase activity in the presence of cyclosarin and an oxime

Worek, Franz, Horn, Gabriele, Wille, Timo, Thiermann, Horst

Journal:

Toxicology in Vitro

Year:

2015

Language:

english

File:

PDF, 1.54 MB

english, 2015

60

Detoxification of G- and V-series nerve agents by the phosphotriesterase OpdA

Wille, Timo, Scott, Colin, Thiermann, Horst, Worek, Franz

Journal:

Biocatalysis and Biotransformation

Year:

2012

Language:

english

File:

PDF, 187 KB

english, 2012

61

PS19 - 90. BMP-7 reduces high fat diet-induced adiposity in mice by activating brown adipose tissue in a sympathetic-dependent way: Implications for obesity

Boon, Mariëtte R., van den Berg, Sjoerd A., Wang, Yanan, van der Horst, Geertje, Vukicevic, Slobodan, Smit, Johannes W.A., Havekes, Louis M., Tamsma, Jouke T., van der Pluijm, Gabri, van Dijk, Ko Will

Journal:

Nederlands Tijdschrift voor Diabetologie

Year:

2012

Language:

english

File:

PDF, 304 KB

english, 2012

62

PS9 - 12. Involvement of zinc in the fatty acid transport function of CD36: a novel link to type 2 diabetes

Angin, Yeliz, van den Dikkenberg, Antoinette, Timmers, H.Th. Marc, van der Horst, Dick J., Coumans, Will A., Neumann, Dietbert, Glatz, Jan F.C., Rodenburg, Kees W., Luiken, Joost J.F.P.

Journal:

Nederlands Tijdschrift voor Diabetologie

Year:

2013

Language:

english

File:

PDF, 233 KB

english, 2013

63

Effects of Monoclonal Antibodies on Tissue-Type Plasminogen Activator (t-PA) Binding to Lysine, Fibrin and Heparin and on Fibrin-Mediated Enhancement of One-Chain t-PA Amidolytic Activity

FISCHER, Bernhard, ZACHARIAS, Ute, WILL, Horst

Journal:

Biological Chemistry Hoppe-Seyler

Year:

1991

Language:

english

File:

PDF, 1.46 MB

english, 1991

64

Evaluation of Functional and Structural Alterations in Muscle Tissue after Short-Term Cold Storage in a New Tissue Preservation Solution

Wille, Timo, Gonder, Sascha, Thiermann, Horst, Seeger, Thomas, Rauen, Ursula, Worek, Franz

Journal:

Cells Tissues Organs

Year:

2011

Language:

english

File:

PDF, 572 KB

english, 2011

65

The Effects of Angiotensin-Converting Enzyme Inhibition on the Urinary Excretion of NTproBNP in Male Volunteers

Heringlake, Matthias, Will, Barbara, Klaus, Stephan, Heinze, Hermann, Wagner, Klaus, Pagel, Horst, Wergeland, Ragnhild, Bahlmann, Ludger

Journal:

Kidney & Blood Pressure Research

Year:

2006

Language:

english

File:

PDF, 262 KB

english, 2006

66

Biochemical Characterization of the Catalytic Domain of Membrane-Type 4 Matrix Metalloproteinase

Kolkenbrock, Hansjörg, Essers, Lutz, Ulbrich, Norbert, Will, Horst

Journal:

Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 224 KB

english, 1999

67

Activation of Progelatinase A and Progelatinase A/TIMP-2 Complex by Membrane Type 2-Matrix Metalloproteinase

Kolkenbrock, Hansjörg, Hecker-Kia, Adelheid, Orgel, Dagmar, Ulbrich, Norbert, Will, Horst

Journal:

Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 1.28 MB

english, 1997

68

Evaluation of 6,6′-dithionicotinic acid as alternative chromogen in a modified Ellman method—comparison in various species

Wille, Timo, Thiermann, Horst, Worek, Franz

Journal:

Toxicology Mechanisms and Methods

Year:

2011

Language:

english

File:

PDF, 630 KB

english, 2011

69

Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase

Winter, Michael, Wille, Timo, Musilek, Kamil, Kuca, Kamil, Thiermann, Horst, Worek, Franz

Journal:

Toxicology Letters

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

70

Catalytic bioscavengers in nerve agent poisoning: A promising approach?

Worek, Franz, Thiermann, Horst, Wille, Timo

Journal:

Toxicology Letters

Year:

2015

Language:

english

File:

PDF, 400 KB

english, 2015

71

Kinetics of pesticide degradation by human fresh frozen plasma (FFP) in vitro

von der Wellen, Jens, Bierwisch, Anne, Worek, Franz, Thiermann, Horst, Wille, Timo

Journal:

Toxicology Letters

Year:

2015

Language:

english

File:

PDF, 901 KB

english, 2015

72

Application of a dynamic in vitro model with real-time determination of acetylcholinesterase activity for the investigation of tabun analogues and oximes

Worek, Franz, Herkert, Nadja M., Koller, Marianne, Thiermann, Horst, Wille, Timo

Journal:

Toxicology in Vitro

Year:

2015

Language:

english

File:

PDF, 569 KB

english, 2015

73

A novel fluorogenic probe for the investigation of free thiols: application to kinetic measurements of acetylcholinesterase activity

Mertens, Matthias D., Bierwisch, Anne, Li, Tianwei, Gütschow, Michael, Thiermann, Horst, Wille, Timo, Elsinghorst, Paul W.

Journal:

Toxicology Letters

Year:

2015

Language:

english

File:

PDF, 923 KB

english, 2015

74

Geschichte

Franz-Willing, Georg, Schallenberger, Horst, Thomas, Michael, Schoeps, Julius H., Gewehr, Wolf, Schoeps, Hans-Joachim

Journal:

Zeitschrift für Religions- und Geistesgeschichte

Year:

1975

Language:

german

File:

PDF, 1.17 MB

german, 1975

75

Kinetic analysis of interactions of amodiaquine with human cholinesterases and organophosphorus compounds

Bierwisch, Anne, Wille, Timo, Thiermann, Horst, Worek, Franz

Journal:

Toxicology Letters

Year:

2016

Language:

english

File:

PDF, 701 KB

english, 2016

76

Neueste Geschichte (1871-1945)

Review by: K. Kluxen, R. V., Georg Franz-Willing, H. Croon, E. Hölzle, H. Hg., H. J. Varain, H. v. Rimscha, Werner Hahlweg and Horst Stuke

Journal:

Historische Zeitschrift

Year:

1958

Language:

german

File:

PDF, 1.32 MB

german, 1958

77

On-site analysis of acetylcholinesterase and butyrylcholinesterase activity with the ChE check mobile test kit—Determination of reference values and their relevance for diagnosis of exposure to organophosphorus compounds

Worek, Franz, Schilha, Martina, Neumaier, Katharina, Aurbek, Nadine, Wille, Timo, Thiermann, Horst, Kehe, Kai

Journal:

Toxicology Letters

Year:

2016

Language:

english

File:

PDF, 1.70 MB

english, 2016

78

Oximes in organophosphate poisoning: 60 years of hope and despair

Worek, Franz, Thiermann, Horst, Wille, Timo

Journal:

Chemico-Biological Interactions

Year:

2016

Language:

english

File:

PDF, 963 KB

english, 2016

79

Reactivation of nerve agent-inhibited human acetylcholinesterase by obidoxime, HI-6 and obidoxime+HI-6: Kinetic in vitro study with simulated nerve agent toxicokinetics and oxime pharmacokinetics

Worek, Franz, Koller, Marianne, Thiermann, Horst, Wille, Timo

Journal:

Year:

2016

Language:

english

File:

PDF, 1.53 MB

english, 2016

80

Bispyridinium non-oximes: An evaluation of cardiac effects in isolated hearts and smooth muscle relaxing effects in jejunum

Neumaier, Katharina, Worek, Franz, Thiermann, Horst, Wille, Timo

Journal:

Toxicology in Vitro

Year:

2016

Language:

english

File:

PDF, 672 KB

english, 2016

81

A phase II/III trial of antimicrobial therapy with or without amikacin in the treatment of disseminated Mycobacterium avium infection in HIV-infected individuals

Parenti, David M., Williams, Paige L., Hafner, Richard, Jacobs, Michael R., Hojczyk, Peter, Hooton, Thomas M., Barber, Thomas W., Simpson, Gail, der Horst, Charles van, Currier, Judith, Powderly, Will

Journal:

Year:

1998

File:

PDF, 488 KB

1998

82

Book Reviews

Philips, William, Hogan, Robert, Mendelsohn, Michael, Kelson, John, Wills, Arthur, Frenz, Horst, Frenz, HorstJohn

Journal:

Year:

1963

Language:

english

File:

PDF, 618 KB

english, 1963

83

Pseudocatalytic scavenging of the nerve agent VX with human blood components and the oximes obidoxime and HI-6

Wille, Timo, von der Wellen, Jens, Thiermann, Horst, Worek, Franz

Journal:

Archives of Toxicology

Year:

2017

Language:

english

File:

PDF, 2.06 MB

english, 2017

84

Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: Intraosseous versus intravenous injection

Wille, Timo, Neumaier, Katharina, Koller, Marianne, Ehinger, Christina, Aggarwal, Nidhi, Ashani, Yacov, Goldsmith, Moshe, Sussman, Joel L., Tawfik, Dan S., Thiermann, Horst, Worek, Franz

Journal:

Toxicology Letters

Year:

2016

Language:

english

File:

PDF, 901 KB

english, 2016

85

Blaptica dubia as sentinels for exposure to chemical warfare agents − a pilot study

Worek, Franz, Seeger, Thomas, Neumaier, Katharina, Wille, Timo, Thiermann, Horst

Journal:

Toxicology Letters

Year:

2016

Language:

english

File:

PDF, 493 KB

english, 2016

86

Rational design of cyclic peptide inhibitors of U2AF homology motif (UHM) domains to modulate pre-mRNA splicing

Jagtap, Pravin Kumar Ankush, Garg, Divita, Kapp, Tobias G., Will, Cindy L., Demmer, Oliver, Luhrmann, Reinhard, Kessler, Horst, Sattler, Michael

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.16 MB

english, 2016

87

Precision Cut Lung Slices as test system for candidate therapeutics in organophosphate poisoning

Herbert, Julia, Thiermann, Horst, Worek, Franz, Wille, Timo

Journal:

Year:

2017

Language:

english

File:

PDF, 697 KB

english, 2017

88

Development of a sensitive, generic and easy to use organophosphate skin disclosure kit

Worek, Franz, Wosar, Andreas, Baumann, Madlen, Thiermann, Horst, Wille, Timo

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 541 KB

english, 2017

89

Human small bowel as a useful tool to investigate smooth muscle effects of potential therapeutics in organophosphate poisoning

Marquart, Katharina, Prokopchuk, Olga, Worek, Franz, Thiermann, Horst, Martignoni, Marc E., Wille, Timo

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 849 KB

english, 2017

90

Effect of cholinergic crisis on the potency of different emergency anaesthesia protocols in soman-poisoned rats

Marquart, Katharina, Herbert, Julia, Amend, Niko, Thiermann, Horst, Worek, Franz, Wille, Timo

Journal:

Clinical Toxicology (Informa Healthcare)

Year:

2018

Language:

english

File:

PDF, 1.09 MB

english, 2018

91

Human small bowel as model for poisoning with organophosphorus compounds

Marquart, Katharina, Prokopchuk, Olga, Wilhelm, Dirk, Worek, Franz, Thiermann, Horst, Martignoni, Marc E., Wille, Timo

Journal:

Toxicology in Vitro

Year:

2019

Language:

english

File:

PDF, 1.77 MB

english, 2019

92

The arrhythmogenic potential of nerve agents and a cardiac safety profile of antidotes - A proof-of-concept study using human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CM)

Amend, Niko, Thiermann, Horst, Worek, Franz, Wille, Timo

Journal:

Toxicology Letters

Year:

2019

Language:

english

File:

PDF, 624 KB

english, 2019

93

The Second ECVAM Workshop on Phototoxicity Testing

Spielmann, Horst, Müller, Lutz, Averbeck, Dietrich, Balls, Michael, Brendler-Schwaab, Susanne, Castell, José V., Curren, Rodger, de Silva, Odile, Gibbs, Neil K., Liebsch, Manfred, Lovell, Will W., Mer

Journal:

Alternatives to laboratory animals : ATLA

Year:

2000

File:

PDF, 176 KB

2000

94

Vergiftungen durch chemische Kampfstoffe; Chemical warfare agent poisoning;

Wille, Timo, Steinritz, Dirk, Worek, Franz, Thiermann, Horst

Journal:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Year:

2019

Language:

german

File:

PDF, 535 KB

german, 2019

95

Diagnostics and treatment of nerve agent poisoning-current status and future developments

Amend, Niko, Niessen, Karin V., Seeger, Thomas, Wille, Timo, Worek, Franz, Thiermann, Horst

Journal:

Annals of the New York Academy of Sciences

Year:

2020

Language:

english

File:

PDF, 1.13 MB

english, 2020

96

Early diagnosis of nerve agent exposure with a mobile test kit and implications for medical countermeasures: a trigger to react

Wille, Timo, DjordjeviÄ, Snezana, Worek, Franz, Thiermann, Horst, VuÄiniÄ, Slavica

Journal:

BMJ Military Health

Year:

2020

File:

PDF, 668 KB

2020

97

Organophosphorus compounds and oximes: a critical review

Worek, Franz, Thiermann, Horst, Wille, Timo

Journal:

Archives of Toxicology

Year:

2020

File:

PDF, 1.34 MB

2020

98

In Vitro Interaction of Organophosphono- and Organophosphorothioates with Human Acetylcholinesterase

Worek, Franz, Thiermann, Horst, Koller, Marianne, Wille, Timo

Journal:

Year:

2020

File:

PDF, 690 KB

2020

99

Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly

Jagtap, Pravin Kumar Ankush, Kubelka, TomÃ¡Å¡, Soni, Komal, Will, Cindy L., Garg, Divita, Sippel, Claudia, Kapp, Tobias G., Potukuchi, Harish Kumar, Schorpp, Kenji, Hadian, Kamyar, Kessler, Horst, LÃ¼

Journal:

Nature Communications

Year:

2020

File:

PDF, 1.59 MB

2020