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51

Quinine Dimers Are Potent Inhibitors of the Plasmodium falciparum Chloroquine Resistance Transporter and Are Active against Quinoline-Resistant P. falciparum

Hrycyna, Christine A., Summers, Robert L., Lehane, Adele M., Pires, Marcos M., Namanja, Hilda, Bohn, Kelsey, Kuriakose, Jerrin, Ferdig, Michael, Henrich, Philipp P., Fidock, David A., Kirk, Kiaran, Ch

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 950 KB

english, 2014

52

Protein Carboxyl Methylation in Saccharomyces cerevisiae: Evidence for STE14-Dependent and STE14-Independent Pathways

Hrycyna, Christine A., Yang, Melody C., Clarke, Steven

Journal:

Year:

1994

Language:

english

File:

PDF, 902 KB

english, 1994

53

Reversible Dimers of the Atypical Antipsychotic Quetiapine Inhibit P-Glycoprotein-Mediated Efflux in Vitro with Increased Binding Affinity and in Situ at the Blood-Brain Barrier

Emmert, Dana, Campos, Christopher R., Ward, David, Lu, Peihua, Namanja, Hilda A., Bohn, Kelsey, Miller, David S., Sharom, Frances J., Chmielewski, Jean, Hrycyna, Christine A.

Journal:

ACS Chemical Neuroscience

Year:

2014

Language:

english

File:

PDF, 2.55 MB

english, 2014

54

Functional Reconstitution of the Integral Membrane Enzyme, Isoprenylcysteine Carboxyl Methyltransferase, in Synthetic Bolalipid Membrane Vesicles †

Febo-Ayala, Wilma, Morera-Félix, Shakira L., Hrycyna, Christine A., Thompson, David H.

Journal:

Year:

2006

Language:

english

File:

PDF, 257 KB

english, 2006

55

Effective dynamics of the closed loop quantum cosmology

Mielczarek, Jakub, Hrycyna, Orest, Szydłowski, Marek

Journal:

Journal of Cosmology and Astroparticle Physics

Year:

2009

Language:

english

File:

PDF, 312 KB

english, 2009

56

N-Linked Glycosylation of the Human ABC Transporter ABCG2 on Asparagine 596 Is Not Essential for Expression, Transport Activity, or Trafficking to the Plasma Membrane †

Diop, Ndeye K., Hrycyna, Christine A.

Journal:

Year:

2005

Language:

english

File:

PDF, 455 KB

english, 2005

57

Inhibition of Membrane-Associated Methyltransferases by a Cholesterol-Based Metal Chelator

Hodges, Heather B., Zhou, Mingkang, Haldar, Saubhik, Anderson, Jessica L., Thompson, David H., Hrycyna, Christine A.

Journal:

Bioconjugate Chemistry

Year:

2005

Language:

english

File:

PDF, 86 KB

english, 2005

58

Purification and characterization of a novel metalloendopeptidase from Saccharomyces cerevisiae

Hrycyna, Christine A., Clarke, Steven

Journal:

Year:

1993

Language:

english

File:

PDF, 2.11 MB

english, 1993

59

150 years of changes in bird life in Cambridge, Massachusetts from 1860 to 2012

Strohbach, Michael W., Hrycyna, Andrew, Warren, Paige S.

Journal:

The Wilson Journal of Ornithology

Year:

2014

Language:

english

File:

PDF, 6.12 MB

english, 2014

60

Identification of a novel nanomolar inhibitor of hIcmt via a carboxylate replacement approach

Majmudar, Jaimeen D., Morrison-Logue, Amanda, Song, Jiao, Hrycyna, Christine A., Gibbs, Richard A.

Journal:

Year:

2012

Language:

english

File:

PDF, 278 KB

english, 2012

61

Dynamic Combinatorial Libraries of 2,5-Diformylfuran-Derived Macrocycles

Ziach, Krzysztof, Obrocka-Hrycyna, Aleksandra, Jurczak, Janusz

Journal:

Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 546 KB

english, 2014

62

Quantum theory of the Bianchi II model

Bergeron, Hervé, Hrycyna, Orest, Małkiewicz, Przemysław, Piechocki, Włodzimierz

Journal:

Physical Review D

Year:

2014

Language:

english

File:

PDF, 335 KB

english, 2014

63

Dynamics and cosmological constraints on Brans-Dicke cosmology

Hrycyna, Orest, Szydłowski, Marek, Kamionka, Michał

Journal:

Physical Review D

Year:

2014

Language:

english

File:

PDF, 753 KB

english, 2014

64

Paths of Friedmann–Robertson–Walker brane models

Szydłowski, Marek, Hrycyna, Orest

Journal:

Journal of Mathematical Physics

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

65

Functional Oligomerization of the Saccharomyces cerevisiae Isoprenylcysteine Carboxyl Methyltransferase, Ste14p

Griggs, A. M., Hahne, K., Hrycyna, C. A.

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 1.37 MB

english, 2010

66

Inhibition of P-Glycoprotein-Mediated Paclitaxel Resistance by Reversibly Linked Quinine Homodimers

Pires, M. M., Emmert, D., Hrycyna, C. A., Chmielewski, J.

Journal:

Molecular Pharmacology

Year:

2009

Language:

english

File:

PDF, 393 KB

english, 2009

67

HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells

Coffinier, C., Hudon, S. E., Farber, E. A., Chang, S. Y., Hrycyna, C. A., Young, S. G., Fong, L. G.

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 914 KB

english, 2007

68

Purification, Functional Reconstitution, and Characterization of the Saccharomyces cerevisiae Isoprenylcysteine Carboxylmethyltransferase Ste14p

Anderson, J. L., Frase, H., Michaelis, S., Hrycyna, C. A.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 802 KB

english, 2005

69

Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24

Chang, S. Y., Hudon-Miller, S. E., Yang, S. H., Jung, H.-J., Lee, J. M., Farber, E., Subramanian, T., Andres, D. A., Spielmann, H. P., Hrycyna, C. A., Young, S. G., Fong, L. G.

Journal:

The Journal of Lipid Research

Year:

2012

Language:

english

File:

PDF, 760 KB

english, 2012

70

Functional characterization of a glycine 185-to-valine substitution in human P-glycoprotein by using a vaccinia-based transient expression system.

Ramachandra, M., Ambudkar, S. V., Gottesman, M. M., Pastan, I., Hrycyna, C. A.

Journal:

Molecular Biology of the Cell

Year:

1996

Language:

english

File:

PDF, 2.65 MB

english, 1996

71

Mechanism of Action of Human P-glycoprotein ATPase Activity. PHOTOCHEMICAL CLEAVAGE DURING A CATALYTIC TRANSITION STATE USING ORTHOVANADATE REVEALS CROSS-TALK BETWEEN THE TWO ATP SITES

Journal:

Journal of Biological Chemistry

Year:

1998

Language:

english

File:

PDF, 733 KB

english, 1998

72

A Potent HIV Protease Inhibitor, Darunavir, Does Not Inhibit ZMPSTE24 or Lead to an Accumulation of Farnesyl-prelamin A in Cells

Coffinier, C., Hudon, S. E., Lee, R., Farber, E. A., Nobumori, C., Miner, J. H., Andres, D. A., Spielmann, H. P., Hrycyna, C. A., Fong, L. G., Young, S. G.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 943 KB

english, 2008

73

Scalar field cosmology — geometry of dynamics

Szydłowski, Marek, Hrycyna, Orest, Stachowski, Aleksander

Journal:

International Journal of Geometric Methods in Modern Physics

Year:

2014

Language:

english

File:

PDF, 3.53 MB

english, 2014

74

Substrate Overlap between Mrp4 and Abcg2/Bcrp Affects Purine Analogue Drug Cytotoxicity and Tissue Distribution

Takenaka, K., Morgan, J. A., Scheffer, G. L., Adachi, M., Stewart, C. F., Sun, D., Leggas, M., Ejendal, K. F.K., Hrycyna, C. A., Schuetz, J. D.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 529 KB

english, 2007

75

Human ZMPSTE24 disease mutations: residual proteolytic activity correlates with disease severity

Barrowman, J., Wiley, P. A., Hudon-Miller, S. E., Hrycyna, C. A., Michaelis, S.

Journal:

Human Molecular Genetics

Year:

2012

Language:

english

File:

PDF, 370 KB

english, 2012

76

The Isoprenoid Substrate Specificity of Isoprenylcysteine Carboxylmethyltransferase

Anderson, Jessica L., Henriksen, Brian S., Gibbs, Richard A., Hrycyna, Christine A.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 753 KB

english, 2005

77

Dynamical complexity of the Brans-Dicke cosmology

O. Hrycyna, M. Szydłowski

Year:

2013

Language:

english

File:

PDF, 2.06 MB

english, 2013

78

Phantom cosmology as a scattering process

M. Szydłowski, O. Hrycyna, A. Krawiec

Year:

2007

Language:

english

File:

PDF, 1.32 MB

english, 2007

79

Uniting cosmological epochs through the twister solution in cosmology with non-minimal coupling

Hrycyna, Orest, Szydłowski, Marek

Journal:

Journal of Cosmology and Astroparticle Physics

Year:

2010

Language:

english

File:

PDF, 827 KB

english, 2010

80

Scalar field cosmology in the energy phase-space—unified description of dynamics

Szydłowski, Marek, Hrycyna, Orest

Journal:

Journal of Cosmology and Astroparticle Physics

Year:

2009

Language:

english

File:

PDF, 338 KB

english, 2009

81

Synthesis of Amide-Modified Farnesyl-cysteine Analogues

Donelson, J., Hodges-Loaiza, H., Henriksen, B., Hrycyna, C., Gibbs, R.

Journal:

Year:

2009

Language:

english

File:

PDF, 87 KB

english, 2009

82

Non-minimally coupled scalar field cosmology on the phase plane

O. Hrycyna, M. Szydłowski

Year:

2009

Language:

english

File:

PDF, 564 KB

english, 2009

83

Asymmetric cyclic evolution in polymerised cosmology

O. Hrycyna, J. Mielczarek, M. Szydłowski

Year:

2009

Language:

english

File:

PDF, 363 KB

english, 2009

84

Cosmological dynamics with non-minimally coupled scalar field and a constant potential function

Hrycyna, Orest, Szydłowski, Marek

Journal:

Journal of Cosmology and Astroparticle Physics

Year:

2015

Language:

english

File:

PDF, 1.41 MB

english, 2015

85

Implementation of diverse non-centrosymmetric layer concepts for tuning the interface activity of a magnesium alloy

Stamboroski, Stephani, Stachera, Priscilla Natalli, Ureña, Yendry Regina Corrales, Hrycyna, Gustavo Homann, Neto, Wilson Iraja Taborda Ribas, de Azambuja, Wagner Kazuki, Salz, Dirk, Ihde, Jörg, Noeske

Journal:

Applied Adhesion Science

Year:

2016

Language:

english

File:

PDF, 4.05 MB

english, 2016

86

Farnesyl cysteine C-terminal methyltransferase activity is dependent upon the STE14 gene product in Saccharomyces cerevisiae.

Hrycyna, C A, Clarke, S

Journal:

Molecular and Cellular Biology

Year:

1990

Language:

english

File:

PDF, 1.06 MB

english, 1990

87

Research Spotlight: Tools for eradicating HIV in the brain: prodrug dimeric inhibitors of P-gp

Chmielewski, Jean, Hrycyna, Christine

Journal:

Therapeutic Delivery

Year:

2012

Language:

english

File:

PDF, 427 KB

english, 2012

88

[Methods in Enzymology] ABC Transporters: Biochemical, Cellular, and Molecular Aspects Volume 292 || [33] Functional expression of human P-glycoprotein from plasmids using vaccinia virus-bacteriophage T7 RNA polymerase system

Hrycyna, Christine A.

Year:

1998

Language:

english

File:

PDF, 839 KB

english, 1998

89

Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24

CORRIGAN, Douglas P., KUSZCZAK, Danuta, RUSINOL, Antonio E., THEWKE, Douglas P., HRYCYNA, Christine A., MICHAELIS, Susan, SINENSKY, Michael S.

Journal:

Biochemical Journal

Year:

2005

Language:

english

File:

PDF, 402 KB

english, 2005

90

What ξ ? Cosmological constraints on the non-minimal coupling constant

Journal:

Physics Letters B

Year:

2017

Language:

english

File:

PDF, 775 KB

english, 2017

91

Dual Modulation of Human P-Glycoprotein and ABCG2 with Prodrug Dimers of the Atypical Antipsychotic Agent Paliperidone in a Model of the Blood–Brain Barrier

Bohn, Kelsey, Lange, Allison, Chmielewski, Jean, Hrycyna, Christine A.

Journal:

Molecular Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 1.51 MB

english, 2017

92

Dual inhibitors of the human blood-brain barrier drug efflux transporters P-glycoprotein and ABCG2 based on the antiviral azidothymidine

Namanja-Magliano, Hilda A., Bohn, Kelsey, Agrawal, Neha, Willoughby, Meghan E., Hrycyna, Christine A., Chmielewski, Jean

Journal:

Bioorganic & Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 472 KB

english, 2017

93

[Methods in Enzymology] Lipid Modifications of Proteins Volume 250 || [21] Yeast STE 14 methyltransferase, expressed as TrpE-STE 14 fusion protein in Escherichia coli, for in Vitro Carboxylmethylation of prenylated polypeptides

Hrycyna, Christine A.

Year:

1995

Language:

english

File:

PDF, 801 KB

english, 1995

94

AIP Conference Proceedings [AIP MULTIVERSE AND FUNDAMENTAL COSMOLOGY: Multicosmofun '12 - Szczecin, Poland (10–14 September 2012)] - Dynamics of the Bianchi I model with non-minimally coupled scalar field near the singularity

Hrycyna, Orest, Szydłowski, Marek

Year:

2013

Language:

english

File:

PDF, 833 KB

english, 2013

95

a-Factor analogues containing alkyne- and azide functionalized isoprenoids are efficiently enzymatically processed and retain wild type bioactivity

Diaz-Rodriguez, Veronica, Hsu, Erh-Ting, Ganusova, Elena, Werst, Elena, Becker, Jeffrey Marvin, Hrycyna, Christine A., Distefano, Mark D.

Journal:

Bioconjugate Chemistry

Year:

2017

Language:

english

File:

PDF, 6.54 MB

english, 2017

96

ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stability

Spear, Eric D., Hsu, Erh-Ting, Nie, Laiyin, Carpenter, Elisabeth P., Hrycyna, Christine A., Michaelis, Susan

Journal:

Disease Models & Mechanisms

Year:

2018

Language:

english

File:

PDF, 6.03 MB

english, 2018

97

[ 3 H]Dexamethasone Binding to Plasma Membrane-Enriched Fractions from Liver of Nonadrenalectomized Rats*

QUELLE, FREDERICK W., SMITH, RICHARD V., HRYCYNA, CHRISTINE A., KALIBAN, TIMOTHY D., CROOKS, JOAN A., O'BRIEN, JANE M.

Journal:

Year:

1988

Language:

english

File:

PDF, 1.22 MB

english, 1988

98

Muscle torques of lower leg rotators in untrained subjects

Hrycyna, Mariusz, Zieliński, Jacek

Journal:

Biomedical Human Kinetics

Year:

2011

Language:

english

File:

PDF, 430 KB

english, 2011

99

The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins.

Hrycyna, C.A., Sapperstein, S.K., Clarke, S., Michaelis, S.

Journal:

The EMBO Journal

Year:

1991

Language:

english

File:

PDF, 2.42 MB

english, 1991

100

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Wang, Chao, Zhang, Bin, Ratliff, Anna C., Arrington, Justine, Chen, Jingjuan, Xiong, Yan, Yue, Feng, Nie, Yaohui, Hu, Keping, Jin, Wen, Tao, W. Andy, Hrycyna, Christine A., Sun, Xiaobo, Kuang, Shihuan

Journal:

The FASEB Journal

Year:

2019

Language:

english

File:

PDF, 2.78 MB

english, 2019