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51

Disseminated disease severity as a measure of virulence of Mycobacterium tuberculosis in the guinea pig model

Gopinath S. Palanisamy, Erin E. Smith, Crystal A. Shanley, Diane J. Ordway, Ian M. Orme, Randall J. Basaraba

Journal:

Year:

2008

Language:

english

File:

PDF, 15.40 MB

english, 2008

52

Post-exposure vaccination against Mycobacterium tuberculosis

Marcela Henao-Tamayo, Gopinath S. Palaniswamy, Erin E. Smith, Crystal A. Shanley, Baolin Wang, Ian M. Orme, Randall J. Basaraba, Nancy M. DuTeau, Diane Ordway

Journal:

Year:

2009

Language:

english

File:

PDF, 1.74 MB

english, 2009

53

Clinical strains of Mycobacterium tuberculosis display a wide range of virulence in guinea pigs

Gopinath S. Palanisamy, Nancy DuTeau, Kathleen D. Eisenach, Donald M. Cave, Susan A. Theus, Barry N. Kreiswirth, Randall J. Basaraba, Ian M. Orme

Journal:

Year:

2009

Language:

english

File:

PDF, 869 KB

english, 2009

54

Evaluation of new vaccines for tuberculosis in the guinea pig model

Ann Williams, Yper Hall, Ian M. Orme

Journal:

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

55

Lack of IL-10 alters inflammatory and immune responses during pulmonary Mycobacterium tuberculosis infection

David M. Higgins, Joaquin Sanchez-Campillo, Adrian G. Rosas-Taraco, Eric J. Lee, Ian M. Orme, Mercedes Gonzalez-Juarrero

Journal:

Year:

2009

Language:

english

File:

PDF, 3.43 MB

english, 2009

56

Local pulmonary immunotherapy with siRNA targeting TGFβ1 enhances antimicrobial capacity in Mycobacterium tuberculosis infected mice

Adrian G. Rosas-Taraco, David M. Higgins, Joaquín Sánchez-Campillo, Eric J. Lee, Ian M. Orme, Mercedes González-Juarrero

Journal:

Year:

2011

Language:

english

File:

PDF, 1.42 MB

english, 2011

57

The Achilles heel of BCG

Journal:

Year:

2010

Language:

english

File:

PDF, 121 KB

english, 2010

58

Increased Foxp3 expression in guinea pigs infected with W-Beijing strains of M. tuberculosis

Shaobin Shang, Marisa Harton, Marcela Henao Tamayo, Crystal Shanley, Gopinath S. Palanisamy, Megan Caraway, Edward D. Chan, Randall J. Basaraba, Ian M. Orme, Diane J. Ordway

Journal:

Year:

2011

Language:

english

File:

PDF, 1.48 MB

english, 2011

59

T lymphocyte surface expression of exhaustion markers as biomarkers of the efficacy of chemotherapy for tuberculosis

Marcela Henao-Tamayo, Scott M. Irwin, Shaobin Shang, Diane Ordway, Ian M. Orme

Journal:

Year:

2011

Language:

english

File:

PDF, 902 KB

english, 2011

60

Natural infection of guinea pigs exposed to patients with highly drug-resistant tuberculosis

Ashwin S. Dharmadhikari, Randall J. Basaraba, Martie L. Van Der Walt, Karin Weyer, Matsie Mphahlele, Kobus Venter, Paul A. Jensen, Melvin W. First, Sydney Parsons, David N. McMurray, Ian M. Orme, Edwa

Journal:

Year:

2011

Language:

english

File:

PDF, 700 KB

english, 2011

61

BCG: Myths, realities, and the need for alternative vaccine strategies

Helen McShane, William R. Jacobs, Paul E. Fine, Steven G. Reed, David N. McMurray, Marcel Behr, Ann Williams, Ian M. Orme

Journal:

Year:

2012

Language:

english

File:

PDF, 128 KB

english, 2012

62

Non-invasive diagnosis of early pulmonary disease in PECAM-deficient mice using infrared pulse oximetry

Merideth A. Early, Marta Lishnevsky, John M. Gilchrist, David M. Higgins, Ian M. Orme, William A. Muller, Mercedes Gonzalez-Juarerro, Alan R. Schenkel

Journal:

Experimental and Molecular Pathology

Year:

2009

Language:

english

File:

PDF, 727 KB

english, 2009

63

CD4 is required for the development of a protective granulomatous response to pulmonary tuberculosis

Bernadette M Saunders, Anthony A Frank, Ian M Orme, Andrea M Cooper

Journal:

Cellular Immunology

Year:

2002

Language:

english

File:

PDF, 409 KB

english, 2002

64

Florid pulmonary inflammatory responses in mice vaccinated with Antigen-85 pulsed dendritic cells and challenged by aerosol with Mycobacterium tuberculosis

Mercedes González-Juarrero, Joanne Turner, Randall J. Basaraba, John T. Belisle, Ian M. Orme

Journal:

Cellular Immunology

Year:

2002

Language:

english

File:

PDF, 391 KB

english, 2002

65

Changes in integrin/adhesion molecule expression, but not in the T-cell receptor repertoire, in old mice infected with tuberculosis

Ian M Orme, Alan D Roberts

Journal:

Mechanisms of Ageing and Development

Year:

1998

Language:

english

File:

PDF, 392 KB

english, 1998

66

Similar responses by macrophages from young and old mice infected with Mycobacterium tuberculosis

Elizabeth R Rhoades, Ian M Orme

Journal:

Mechanisms of Ageing and Development

Year:

1998

Language:

english

File:

PDF, 94 KB

english, 1998

67

Identification of altered integrin α/β chain expression on T cells from old mice infected with Mycobacterium tuberculosis

Joanne Turner, Ian M Orme

Journal:

Experimental Gerontology

Year:

2002

Language:

english

File:

PDF, 233 KB

english, 2002

68

Influence of increased age on the development of herpes stromal keratitis

Joanne Turner, Oliver C Turner, Nick Baird, Ian M Orme, Christine L Wilcox, Susan L Baldwin

Journal:

Experimental Gerontology

Year:

2003

Language:

english

File:

PDF, 303 KB

english, 2003

69

Beyond BCG: the potential for a more effective TB vaccine

Journal:

Molecular Medicine Today

Year:

1999

Language:

english

File:

PDF, 296 KB

english, 1999

70

Frank Miles Collins: (March 30, 1928–November 2, 2002)

Michael J Brennan, Sheldon L Morris, Ian M Orme

Journal:

Year:

2003

Language:

english

File:

PDF, 48 KB

english, 2003

71

Mechanisms Underlying the Increased Susceptibility of Aged Mice to Tuberculosis

Journal:

Nutrition Reviews

Year:

1995

Language:

english

File:

PDF, 430 KB

english, 1995

72

Adaptive immunity to mycobacteria

Journal:

Current Opinion in Microbiology

Year:

2004

Language:

english

File:

PDF, 98 KB

english, 2004

73

Incorporation of CpG oligodeoxynucleotide fails to enhance the protective efficacy of a subunit vaccine against Mycobacterium tuberculosis

Meng-Jer Hsieh, Ana-Paula Junqueira-Kipnis, A Hoeffer, Oliver C Turner, Ian M Orme

Journal:

Year:

2004

Language:

english

File:

PDF, 526 KB

english, 2004

74

Current progress in tuberculosis vaccine development

Journal:

Year:

2005

Language:

english

File:

PDF, 59 KB

english, 2005

75

Protection of mice and guinea pigs against tuberculosis induced by immunization with a single Mycobacterium tuberculosis recombinant antigen, MTB41

Yasir A.W. Skeiky, Mark R. Alderson, Pamela J. Ovendale, Yves Lobet, Wilfried Dalemans, Ian M. Orme, Steven G. Reed, Antonio Campos-Neto

Journal:

Year:

2005

Language:

english

File:

PDF, 342 KB

english, 2005

76

Preclinical testing of new vaccines for tuberculosis: A comprehensive review

Journal:

Year:

2006

Language:

english

File:

PDF, 282 KB

english, 2006

77

Decreased survival of guinea pigs infected with Mycobacterium tuberculosis after multiple BCG vaccinations

Randall J. Basaraba, Angelo A. Izzo, Lise Brandt, Ian M. Orme

Journal:

Year:

2006

Language:

english

File:

PDF, 3.27 MB

english, 2006

78

A mutant of Mycobacterium tuberculosis lacking the 19-kDa lipoprotein Rv3763 is highly attenuated in vivo but retains potent vaccinogenic properties

Marcela Henao-Tamayo, Ana Paula Junqueira-Kipnis, Diane Ordway, Mercedes Gonzales-Juarrero, Graham R. Stewart, Douglas B. Young, Robert J. Wilkinson, Randall J. Basaraba, Ian M. Orme

Journal:

Year:

2007

Language:

english

File:

PDF, 1.15 MB

english, 2007

79

Identification of Mycobacterium tuberculosis vaccine candidates using human CD4+ T-cells expression cloning

Rhea N. Coler, Davin C. Dillon, Yasir A.W. Skeiky, Maria Kahn, Ian M. Orme, Yves Lobet, Steven G. Reed, Mark R. Alderson

Journal:

Year:

2009

Language:

english

File:

PDF, 871 KB

english, 2009

80

Vaccination of guinea pigs using mce operon mutants of Mycobacterium tuberculosis

Andrés Obregón-Henao, Crystal Shanley, María Verónica Bianco, Angel A. Cataldi, Randall J. Basaraba, Ian M. Orme, Fabiana Bigi

Journal:

Year:

2011

Language:

english

File:

PDF, 839 KB

english, 2011

81

Drug treatment combined with BCG vaccination reduces disease reactivation in guinea pigs infected with Mycobacterium tuberculosis

Shaobin Shang, Crystal A. Shanley, Megan L. Caraway, Eileen A. Orme, Marcela Henao-Tamayo, Laurel Hascall-Dove, David Ackart, Ian M. Orme, Diane J. Ordway, Randall J. Basaraba

Journal:

Year:

2012

Language:

english

File:

PDF, 1.56 MB

english, 2012

82

Identification of novel immunogenic Mycobacterium tuberculosis peptides that stimulate mononuclear cells from immune donors

Alison J Moran, James L Doran, Jiong Wu, Janice D Treit, Pattama Ekpo, Valerie J Kerr, Alan D Roberts, Ian M Orme, Shirleen Galant, Stanley R Ress, Francis E Nano

Journal:

FEMS Microbiology Letters

Year:

1999

Language:

english

File:

PDF, 164 KB

english, 1999

83

Tuberculosis vaccine development: recent progress

Ian M. Orme, David N. McMurray, John T. Belisle

Journal:

Trends in Microbiology

Year:

2001

Language:

english

File:

PDF, 289 KB

english, 2001

84

Prospects for new vaccines against tuberculosis

Journal:

Trends in Microbiology

Year:

1995

Language:

english

File:

PDF, 587 KB

english, 1995

85

The immunopathogenesis of tuberculosis: a new working hypothesis

Journal:

Trends in Microbiology

Year:

1998

Language:

english

File:

PDF, 1.52 MB

english, 1998

86

TB vaccine development: after the flood

Ian M Orme, John T Belisle

Journal:

Trends in Microbiology

Year:

1999

Language:

english

File:

PDF, 100 KB

english, 1999

87

Towards controlling mycobacterial infections

Journal:

Trends in Microbiology

Year:

1999

Language:

english

File:

PDF, 81 KB

english, 1999

88

Preclinical testing of new drugs for tuberculosis: current challenges

Anne J. Lenaerts, Mary Ann DeGroote, Ian M. Orme

Journal:

Trends in Microbiology

Year:

2008

Language:

english

File:

PDF, 227 KB

english, 2008

89

An age-related loss of the isogeneic barrier to the successful passive cell transfer of antimicrobial immunity in mice

Journal:

Mechanisms of Ageing and Development

Year:

1988

Language:

english

File:

PDF, 250 KB

english, 1988

90

Significant increases in the levels of liver enzymes in mice treated with anti-tuberculosis drugs

Anne J. Lenaerts, Christine M. Johnson, Karen S. Marrieta, Veronica Gruppo, Ian M. Orme

Journal:

International Journal of Antimicrobial Agents

Year:

2005

Language:

english

File:

PDF, 103 KB

english, 2005

91

Immunology and vaccinology of tuberculosis: can lessons from the mouse be applied to the cow?

Journal:

Year:

2001

Language:

english

File:

PDF, 313 KB

english, 2001

92

Tuberculosis Vaccines

Professor Ian M. Orme

Journal:

Year:

2005

Language:

english

File:

PDF, 141 KB

english, 2005

93

Mycobacterium tuberculosis Universal Stress Protein Rv2623 Regulates Bacillary Growth by ATP-Binding: Requirement for Establishing Chronic Persistent Infection

Drumm, Joshua E., Mi, Kaixia, Bilder, Patrick, Sun, Meihao, Lim, Jihyeon, Bielefeldt-Ohmann, Helle, Basaraba, Randall, So, Melvin, Zhu, Guofeng, Tufariello, JoAnn M., Izzo, Angelo A., Orme, Ian M., Al

Journal:

Year:

2009

Language:

english

File:

PDF, 1.46 MB

english, 2009

94

Vaccine Development for Tuberculosis: Current Progress

Journal:

Year:

2013

Language:

english

File:

PDF, 275 KB

english, 2013

95

[Advances in Veterinary Medicine] Veterinary Vaccines and Diagnostics Volume 41 || Vaccination against tuberculosis: Recent progress

Year:

1999

Language:

english

File:

PDF, 515 KB

english, 1999

96

A new unifying theory of the pathogenesis of tuberculosis

Journal:

Year:

2014

Language:

english

File:

PDF, 447 KB

english, 2014

97

TB's terrible toll

Journal:

Nature Medicine

Year:

2014

Language:

english

File:

PDF, 148 KB

english, 2014

98

Therapeutic vaccination against relevant high virulence clinical isolates of Mycobacterium tuberculosis

Shanley, Crystal A., Ireton, Gregory C., Baldwin, Susan L., Coler, Rhea N., Reed, Steven G., Basaraba, Randall J., Orme, Ian M.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.45 MB

english, 2014

99

The Immediate Closure of Gunshot Wounds.

Journal:

Year:

1918

Language:

english

File:

PDF, 335 KB

english, 1918

100

The role of CD8+ T cells in immunity to tuberculosis infection

Journal:

Trends in Microbiology

Year:

1993

Language:

english

File:

PDF, 241 KB

english, 1993