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1

Garlic-derived anticancer agents: Structure and biological activity of ajoene

Catherine H. Kaschula, Roger Hunter, M. Iqbal Parker

Journal:

Year:

2010

Language:

english

File:

PDF, 220 KB

english, 2010

2

Molecular landscape of esophageal cancer: implications for early detection and personalized therapy

Talukdar, Fazlur Rahman, di Pietro, Massimiliano, Secrier, Maria, Moehler, Markus, Goepfert, Katrin, Lima, Sheila Soares Coelho, Pinto, Luis Felipe Ribeiro, Hendricks, Denver, Parker, Mohamed Iqbal, H

Journal:

Annals of the New York Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 732 KB

english, 2018

3

Substituted ajoenes as novel anti-cancer agents

Roger Hunter, Catherine H. Kaschula, Iqbal M. Parker, Mino R. Caira, Philip Richards, Susan Travis, Francois Taute, Thozama Qwebani

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 166 KB

english, 2008

4

Anti-Proliferative Activity of Synthetic Ajoene Analogues on Cancer Cell-Lines

H. Kaschula, Catherine, Hunter, Roger, T. Hassan, Hassan, Stellenboom, Nashia, Cotton, Jonathan, Q. Zhai, Xiao, Iqbal Parker, M.

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 160 KB

english, 2011

5

Not Everyone Fits the Mold: Intratumor and Intertumor Heterogeneity and Innovative Cancer Drug Design and Development

Dzobo, Kevin, Senthebane, Dimakatso Alice, Thomford, Nicholas Ekow, Rowe, Arielle, Dandara, Collet, Parker, M. Iqbal

Journal:

Omics A Journal of Integrative Biology

Year:

2018

Language:

english

File:

PDF, 531 KB

english, 2018

6

Pharmacodynamic Effects of a 6-Hour Regimen of Enoxaparin in Patients Undergoing Primary Percutaneous Coronary Intervention (PENNY PCI Study)

Sumaya, Wael, Parker, William, Fretwell, Rebekah, Hall, Ian, Barmby, David, Richardson, James, Iqbal, Javaid, Adam, Zulfiquar, Morgan, Kenneth, Gunn, Julian, Mason, Annah, Judge, Heather, Gale, Christ

Journal:

Thrombosis and Haemostasis

Year:

2018

Language:

english

File:

PDF, 309 KB

english, 2018

7

Understanding cellular glycan surfaces in the central nervous system

Iqbal, Sameera, Ghanimi Fard, Mina, Everest-Dass, Arun, Packer, Nicolle H., Parker, Lindsay M.

Journal:

Biochemical Society Transactions

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

8

The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells

Kaschula, Catherine H., Tuveri, Rosanna, Ngarande, Ellen, Dzobo, Kevin, Barnett, Christopher, Kusza, Daniel A., Graham, Lisa M., Katz, Arieh A., Rafudeen, Mohamed Suhail, Parker, M. Iqbal, Hunter, Rog

Journal:

Year:

2019

File:

PDF, 2.15 MB

2019

9

The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells

Kaschula, Catherine H., Tuveri, Rosanna, Ngarande, Ellen, Dzobo, Kevin, Barnett, Christopher, Kusza, Daniel A., Graham, Lisa M., Katz, Arieh A., Rafudeen, Mohamed Suhail, Parker, M. Iqbal, Hunter, Rog

Journal:

Year:

2019

Language:

english

File:

PDF, 2.15 MB

english, 2019

10

Characterization of two distinct families of transcription factors that bind to the CCAAT box region of the human COL1A2 gene

Malcolm Collins, Arlene A. Smith, M. Iqbal Parker

Journal:

Journal of Cellular Biochemistry

Year:

1998

Language:

english

File:

PDF, 222 KB

english, 1998

11

Identification of four new translocations involving FGFR1 in myeloid disorders

Jastinder Sohal, Andrew Chase, Sarah Mould, Martin Corcoran, David Oscier, Sameena Iqbal, Sally Parker, Jeanna Welborn, Richard I. Harris, Giovanni Martinelli, Vittorio Montefusco, Paul Sinclair, Brid

Journal:

Genes, Chromosomes and Cancer

Year:

2001

Language:

english

File:

PDF, 271 KB

english, 2001

12

Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors

Sheri F. T. Fong, Erin Dietzsch, Keith S. K. Fong, Peter Hollosi, Lloyd Asuncion, QingPing He, M. Iqbal Parker, Katalin Csiszar

Journal:

Genes, Chromosomes and Cancer

Year:

2007

Language:

english

File:

PDF, 285 KB

english, 2007

13

Esophageal cancer risk in relation to GGC and CAG trinucleotide repeat lengths in the androgen receptor gene

Erin Dietzsch, Ria Laubscher, M. Iqbal Parker

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 168 KB

english, 2003

14

The Karyopherin proteins, Crm1 and Karyopherin β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation

Pauline J. van der Watt, Christopher P. Maske, Denver T. Hendricks, M. Iqbal Parker, Lynette Denny, Dhirendra Govender, Michael J. Birrer, Virna D. Leaner

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 1.10 MB

english, 2009

15

The T-box transcription factor Tbx2: Its role in development and possible implication in cancer

Amaal Abrahams, M. Iqbal Parker, Sharon Prince

Journal:

Year:

2010

Language:

english

File:

PDF, 425 KB

english, 2010

16

Feedback regulation of the α2(1) collagen gene via the Mek–Erk signaling pathway

Kevin Dzobo, Virna D. Leaner, M. Iqbal Parker

Journal:

Year:

2012

Language:

english

File:

PDF, 910 KB

english, 2012

17

A role for Tbx2 in the regulation of the α2(1) collagen gene in human fibroblasts

Huajian Teng, Emily Davis, Amaal Abrahams, Shaheen Mowla, M. Iqbal Parker, Sharon Prince

Journal:

Journal of Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 173 KB

english, 2007

18

Elevation of large-T antigen production by sodium butyrate treatment of SV40-transformed WI-38 fibroblasts

Y. Paul Goldberg, Virna D. Leaner, M. Iqbal Parker

Journal:

Journal of Cellular Biochemistry

Year:

1992

Language:

english

File:

PDF, 839 KB

english, 1992

19

Protected regions in the chicken α2(1) procollagen promoter in differentiated tissues

Sharada L. Truter, M. Iqbal Parker

Journal:

Journal of Cellular Biochemistry

Year:

1994

Language:

english

File:

PDF, 644 KB

english, 1994

20

Transcriptional repression of the α1(I) collagen gene by ras is mediated in part by an intronic AP1 site

James L. Slack, M. Iqbal Parker, Paul Bornstein

Journal:

Journal of Cellular Biochemistry

Year:

1995

Language:

english

File:

PDF, 1.14 MB

english, 1995

21

Functional magnetic resonance cholangiography (fMRC) of the gallbladder and biliary tree with contrast-enhanced magnetic resonance cholangiography

Laura M. Fayad, George A. Holland, Diane Bergin, Nasir Iqbal, Laurence Parker, Paul G. Curcillo II, Thomas E. Kowalski, Pauline Park, Charles Intenzo, Donald G. Mitchell

Journal:

Journal of Magnetic Resonance Imaging

Year:

2003

Language:

english

File:

PDF, 1.15 MB

english, 2003

22

N,N-dimethylaniline as a solvent for intramolecular Diels Alder reactions. Improved yields and changes in stereoisomer ratios

Kathlyn A Parker, Tahir Iqbal

Journal:

Tetrahedron Letters

Year:

1986

Language:

english

File:

PDF, 207 KB

english, 1986

23

Screening of variants for lactase persistence/non-persistence in populations from South Africa and Ghana

Suvi Torniainen, M Iqbal Parker, Ville Holmberg, Elisa Lahtela, Collet Dandara, Irma Jarvela

Journal:

Year:

2009

Language:

english

File:

PDF, 164 KB

english, 2009

24

The 341C/T polymorphism in the GSTP1 gene is associated with increased risk of oesophageal cancer

Dongping Li, Collet Dandara, M Iqbal Parker

Journal:

Year:

2010

Language:

english

File:

PDF, 666 KB

english, 2010

25

CA repeat polymorphism in the promoter region of theCOL1A2gene

Erin Dietzsch, M. Iqbal Parker

Journal:

Journal of Human Genetics

Year:

1999

Language:

english

File:

PDF, 42 KB

english, 1999

26

Clinical implications of introducing a new PSA assay

Ramachandran Venkitaraman, Andrew R. Norman, Jhangir Iqbal, David P. Dearnaley, Alan Horwich, Robert A. Huddart, Chris C. Parker

Journal:

International Urology and Nephrology

Year:

2008

Language:

english

File:

PDF, 200 KB

english, 2008

27

Oesophageal Cancer in Africa

Denver Hendricks, M. Iqbal Parker

Journal:

Year:

2002

Language:

english

File:

PDF, 59 KB

english, 2002

28

Species-Specific Regulation of the α-2(I) Procollagen Gene by Proximal Promoter Elements

Virna D. Leaner, Agatha Masemola, Iqbal M. Parker

Journal:

Year:

2005

Language:

english

File:

PDF, 933 KB

english, 2005

29

Phosphorylation of the α 2(1) procollagen promoter binding proteins is required for promoter activity

Virna D. Leaner, M. Iqbal Parker

Journal:

Year:

2006

Language:

english

File:

PDF, 300 KB

english, 2006

30

Effect of Rooperol on Collagen Synthesis and Cell Growth

Erin Dietzsch, Carl F. d. V. Albrecht, M. Iqbal Parker

Journal:

Year:

1999

Language:

english

File:

PDF, 230 KB

english, 1999

31

Maternal administration of cyclophosphamide induces chromosomal aberrations and inhibits cell number, histone synthesis, and DNA synthesis in preimplantation mouse embryos

Ismail Kola, Peter I. Folb, M. Iqbal Parker

Journal:

Teratogenesis, Carcinogenesis, and Mutagenesis

Year:

1986

Language:

english

File:

PDF, 890 KB

english, 1986

32

Activation and demethylation of the intracisternal A particle genes by 5-azacytidine

Caroline M. Davis, Phillip G. Constantinides, Wieland Gevers, M.Iqbal Parker, Fritz van der Riet, Lynette van Schalkwyk

Journal:

Cell Differentiation and Development

Year:

1989

Language:

english

File:

PDF, 1.99 MB

english, 1989

33

Health research in Africa: getting priorities right

Ole F. Olesen, M. Iqbal Parker

Journal:

Tropical Medicine & International Health

Year:

2012

Language:

english

File:

PDF, 122 KB

english, 2012

34

Approaches to anthracyclines: efficient syntheses of substituted naphthylacetonitriles

Parker, Kathlyn A., Iqbal, Tahir

Journal:

Journal of Organic Chemistry

Year:

1980

Language:

english

File:

PDF, 398 KB

english, 1980

35

Selective Hypermethylation of Transcribed Nucleosomal DNA by Sodium Butyrate

Lidia C. Boffa, Maria R. Mariani, M.Iqbal Parker

Journal:

Experimental Cell Research

Year:

1994

File:

PDF, 244 KB

1994

36

Identification of Cardiac Autoantigens in Human Heart CDNA Libraries Using Acute Rheumatic Fever Sera

Quentin G. Eichbaum, Dave W. Beatty, M.Iqbal Parker

Journal:

Journal of Autoimmunity

Year:

1994

File:

PDF, 795 KB

1994

37

Demethylation of the type I procollagen genes in transformed fibroblasts treated with 5-azacytidine

M.Iqbal Parker, Wieland Gevers

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 1.92 MB

english, 1984

38

Photolon™, a chlorin e6 derivative, triggers ROS production and light-dependent cell death via necrosis

Louise Copley, Pauline van der Watt, Karel W. Wirtz, M. Iqbal Parker, Virna D. Leaner

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2008

Language:

english

File:

PDF, 774 KB

english, 2008

39

CYP3A5 genotypes and risk of oesophageal cancer in two South African populations

Collet Dandara, Robea Ballo, M. Iqbal Parker

Journal:

Year:

2005

Language:

english

File:

PDF, 110 KB

english, 2005

40

Functional characterization of cis-acting elements involved in basal transcription of the human Tbx2 gene: A new insight into the role of Sp1 in transcriptional regulation

Huajian Teng, M. Iqbal Parker, Sharon Prince

Journal:

Year:

2008

Language:

english

File:

PDF, 666 KB

english, 2008

41

Evaluation of DNA damage in a population of bats (Chiroptera) residing in an abandoned monazite mine

Kathleen A. Meehan, Ernest J. Truter, Jacobus P. Slabbert, M.Iqbal Parker

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2004

Language:

english

File:

PDF, 168 KB

english, 2004

42

TCT-96 Influence Of Gender On Clinical Outcomes Following Transcatheter Aortic Valve Implantation: Results From The UK TAVI Registry On Behalf Of The UK TAVI Steering Group And The National Institute For Cardiovascular Outcomes Research

Rasha Al-Lamee, Christopher Broyd, Jessica Parker, Justin Davies, Jamil Mayet, Nilesh Sutaria, Ben Ariff, Beth Unsworth, John Cousins, Colin Bicknell, Jon Anderson, Iqbal Malik, Andrew Chukwuemeka, Ne

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 74 KB

english, 2012

43

Regulation of the Human α2(I) Procollagen Gene by a Trans-Acting Factor

M. IQBAL PARKER, ARLENE A. SMITH, SHARON BOAST, MING WAN SU, FRANCESCO RAMIREZ

Journal:

Annals of the New York Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 307 KB

english, 1990

44

The receptor tyrosine kinase Axl in cancer: Biological functions and therapeutic implications

Paccez, Juliano D., Vogelsang, Matjaz, Parker, M. Iqbal, Zerbini, Luiz F.

Journal:

International Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

45

New Excursions Into the Synthesis and Medicinal Chemistry of the Disulfide Bond

Hunter*, Roger, Kaschula, Catherine, Stellenboom, Nashia, Cotton, Jonathan, Parker, M. Iqbal

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Year:

2013

Language:

english

File:

PDF, 742 KB

english, 2013

46

New approaches to the synthesis of vitamin D metabolites. 2. Effect of some substituents on stereochemistry in the intramolecular cycloadditions of nonatrienes

Parker, Kathyln A., Iqbal, Tahir

Journal:

Journal of Organic Chemistry

Year:

1987

Language:

english

File:

PDF, 1.30 MB

english, 1987

47

Assessment of the cardiovascular safety of saxagliptin in patients with type 2 diabetes mellitus: pooled analysis of 20 clinical trials

Iqbal, Nayyar, Parker, Artist, Frederich, Robert, Donovan, Mark, Hirshberg, Boaz

Journal:

Cardiovascular Diabetology

Year:

2014

Language:

english

File:

PDF, 217 KB

english, 2014

48

Absence of feedback regulation in the synthesis of COL1A1

Dzobo, Kevin, Leaner, Virna D., Parker, M. Iqbal

Journal:

Year:

2014

Language:

english

File:

PDF, 1.51 MB

english, 2014

49

Influence of Gender on Clinical Outcomes Following Transcatheter Aortic Valve Implantation from the UK Transcatheter Aortic Valve Implantation Registry and the National Institute for Cardiovascular Outcomes Research

Al-Lamee, Rasha, Broyd, Christopher, Parker, Jessica, Davies, Justin E., Mayet, Jamil, Sutaria, Nilesh, Ariff, Ben, Unsworth, Beth, Cousins, Jonathan, Bicknell, Colin, Anderson, Jonathan, Malik, Iqbal

Journal:

The American Journal of Cardiology

Year:

2014

Language:

english

File:

PDF, 627 KB

english, 2014

50

Peripheral Blood Mitochondrial DNA/Nuclear DNA (mtDNA/nDNA) Ratio as a Marker of Mitochondrial Toxicities of Stavudine Containing Antiretroviral Therapy in HIV-Infected Malawian Patients

Kampira, Elizabeth, Dzobo, Kevin, Kumwenda, Johnstone, van Oosterhout, Joep J., Parker, M. Iqbal, Dandara, Collet

Journal:

Omics A Journal of Integrative Biology

Year:

2014

Language:

english

File:

PDF, 326 KB

english, 2014