J.J. Wheler: search on Z-Library

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101

Phase I Clinical Trial Outcomes in 93 Patients with Brain Metastases: The MD Anderson Cancer Center Experience

Tsimberidou, A. M., Letourneau, K., Wen, S., Wheler, J., Hong, D., Naing, A., Iskander, N. G., Uehara, C., Kurzrock, R.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 478 KB

english, 2011

102

IS4. Trials in Progress

Naing, A., Falchook, G. S., Fu, S., Amin, H. M., Piha-Paul, S. A., Hong, D. S., Tsimberidou, A. M., Wheler, J. J., Janku, F., Klevesath, M. B., Jego, V., Johne, A., Kurzrock, R., Lannert, H., Heidenre

Journal:

Annals of Oncology

Year:

2012

Language:

english

File:

PDF, 84 KB

english, 2012

103

Electrocardiograms (ECGs) in phase I anticancer drug development: the MD Anderson Cancer Center experience with 8518 ECGs

Naing, A., Veasey-Rodrigues, H., Hong, D. S., Fu, S., Falchook, G. S., Wheler, J. J., Tsimberidou, A. M., Wen, S., Fessahaye, S. N., Golden, E. C., Aaron, J., Ewer, M. S., Kurzrock, R.

Journal:

Annals of Oncology

Year:

2012

Language:

english

File:

PDF, 81 KB

english, 2012

104

Phase I Oncology Studies: Evidence That in the Era of Targeted Therapies Patients on Lower Doses Do Not Fare Worse

Jain, R. K., Lee, J. J., Hong, D., Markman, M., Gong, J., Naing, A., Wheler, J., Kurzrock, R.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 461 KB

english, 2010

105

Change in Tumor Size by RECIST Correlates Linearly With Overall Survival in Phase I Oncology Studies

Jain, R. K., Lee, J. J., Ng, C., Hong, D., Gong, J., Naing, A., Wheler, J., Kurzrock, R.

Journal:

Journal of Clinical Oncology

Year:

2012

Language:

english

File:

PDF, 337 KB

english, 2012

106

Dual HER2 inhibition in combination with anti-VEGF treatment is active in heavily pretreated HER2-positive breast cancer

Falchook, G. S., Moulder, S. L., Wheler, J. J., Jiang, Y., Bastida, C. C., Kurzrock, R.

Journal:

Annals of Oncology

Year:

2013

Language:

english

File:

PDF, 368 KB

english, 2013

107

Target-Based Therapeutic Matching in Early-Phase Clinical Trials in Patients with Advanced Colorectal Cancer and PIK3CA Mutations

Ganesan, P., Janku, F., Naing, A., Hong, D. S., Tsimberidou, A. M., Falchook, G. S., Wheler, J. J., Piha-Paul, S. A., Fu, S., Stepanek, V. M., Lee, J. J., Luthra, R., Overman, M. J., Kopetz, E. S., Wo

Journal:

Molecular Cancer Therapeutics

Year:

2013

Language:

english

File:

PDF, 434 KB

english, 2013

108

A preliminary assessment of glacier melt-model parameter sensitivity and transferability in a dry subarctic environment

MacDougall, A. H., Wheler, B. A., Flowers, G. E.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.63 MB

english, 2011

109

PCI-24781, a Novel Hydroxamic Acid HDAC Inhibitor, Exerts Cytotoxicity and Histone Alterations via Caspase-8 and FADD in Leukemia Cells

Rivera-Del Valle, Nilsa, Gao, Shan, Miller, Claudia P., Fulbright, Joy, Gonzales, Carolina, Sirisawad, Mint, Steggerda, Susanne, Wheler, Jennifer, Balasubramanian, Sriram, Chandra, Joya

Journal:

International Journal of Cell Biology

Year:

2010

Language:

english

File:

PDF, 831 KB

english, 2010

110

Outcomes of Research Biopsies in Phase I Clinical Trials: The MD Anderson Cancer Center Experience

El-Osta, H., Hong, D., Wheler, J., Fu, S., Naing, A., Falchook, G., Hicks, M., Wen, S., Tsimberidou, A. M., Kurzrock, R.

Journal:

Year:

2011

Language:

english

File:

PDF, 70 KB

english, 2011

111

Phase I Trial of a Combination of the Multikinase Inhibitor Sorafenib and the Farnesyltransferase Inhibitor Tipifarnib in Advanced Malignancies

Hong, D. S., Sebti, S. M., Newman, R. A., Blaskovich, M. A., Ye, L., Gagel, R. F., Moulder, S., Wheler, J. J., Naing, A., Tannir, N. M., Ng, C. S., Sherman, S. I., El Naggar, A. K., Khan, R., Trent, J

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 312 KB

english, 2009

112

Cortisol Production Rate in Posttraumatic Stress Disorder

Wheler, G. H. Trevor, Brandon, David, Clemons, Aaron, Riley, Crystal, Kendall, John, Loriaux, D. Lynn, Kinzie, J. David

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2006

Language:

english

File:

PDF, 80 KB

english, 2006

113

Survival of 1,181 Patients in a Phase I Clinic: The MD Anderson Clinical Center for Targeted Therapy Experience

Wheler, J., Tsimberidou, A. M., Hong, D., Naing, A., Falchook, G., Piha-Paul, S., Fu, S., Moulder, S., Stephen, B., Wen, S., Kurzrock, R.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 502 KB

english, 2012

114

The prognostic significance of left ventricular ejection fraction in patients with advanced cancer treated in phase I clinical trials

Said, R., Banchs, J., Wheler, J., Hess, K. R., Falchook, G., Fu, S., Naing, A., Hong, D., Piha-Paul, S., Ye, Y., Yeh, E., Wolff, R. A., Tsimberidou, A. M.

Journal:

Annals of Oncology

Year:

2014

Language:

english

File:

PDF, 177 KB

english, 2014

115

Phase I dose-escalation study of the multikinase inhibitor lenvatinib in patients with advanced solid tumors and in an expanded cohort of patients with melanoma

Hong, D., Kurzrock, R., Wheler, J. J., Naing, A., Falchook, G. S., Fu, S., Kim, K. B., Davies, M. A., Nguyen, L. M., George, G. C., Xu, L., Shumaker, R., Ren, M., Mink, J., Bedell, C., Andresen, C., S

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 830 KB

english, 2015

116

Inhibition of the Ras/Raf/MEK/ERK and RET Kinase Pathways with the Combination of the Multikinase Inhibitor Sorafenib and the Farnesyltransferase Inhibitor Tipifarnib in Medullary and Differentiated Thyroid Malignancies

Hong, David S., Cabanillas, Maria E., Wheler, Jennifer, Naing, Aung, Tsimberidou, Apostolia M., Ye, Lei, Waguespack, Steven G., Hernandez, Mike, El Naggar, Alder K., Bidyasar, Savita, Wright, John, Sh

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2011

Language:

english

File:

PDF, 564 KB

english, 2011

117

A phase 1 study of intermittently administered pazopanib in combination with continuous daily dosing of lapatinib in patients with solid tumors

Henary, H., George, G. C., Wheler, J., Naing, A., Piha-Paul, S., Fu, S., Mistry, R., Zinner, R., Kurzrock, R., Hong, D. S.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2015

Language:

english

File:

PDF, 806 KB

english, 2015

118

Multiple gene aberrations and breast cancer: lessons from super-responders

Wheler, Jennifer J., Atkins, Johnique T., Janku, Filip, Moulder, Stacy L., Yelensky, Roman, Stephens, Philip J., Kurzrock, Razelle

Journal:

Year:

2015

Language:

english

File:

PDF, 1.33 MB

english, 2015

119

Glacier subsurface heat-flux characterizations for energy-balance modelling in the Donjek Range, southwest Yukon, Canada

Wheler, Brett A., Flowers, Gwenn E.

Journal:

Journal of Glaciology

Year:

2011

Language:

english

File:

PDF, 620 KB

english, 2011

120

Dose-finding study of hepatic arterial infusion of irinotecan-based treatment in patients with advanced cancers metastatic to the liver

Said, Rabih, Kurzrock, Razelle, Naing, Aung, Hong, David S., Fu, Siqing, Piha-Paul, Sarina A., Wheler, Jennifer J., Janku, Filip, Kee, Bryan K., Bidyasar, Savita, Lim, Joann, Wallace, Michael, Tsimber

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 330 KB

english, 2015

121

Novel Phase I Study Combining G1 Phase, S Phase, and G2/M Phase Cell Cycle Inhibitors in Patients with Advanced Malignancies

Jain, Rajul K., Hong, David S., Naing, Aung, Wheler, Jennifer, Helgason, Thorunn, Shi, Nai-Yi, Gad, Yash, Kurzrock, Razelle

Journal:

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

122

Multigene Clinical Mutational Profiling of Breast Carcinoma Using Next-Generation Sequencing

Roy-Chowdhuri, S., de Melo Gagliato, D., Routbort, M. J., Patel, K. P., Singh, R. R., Broaddus, R., Lazar, A. J., Sahin, A., Alvarez, R. H., Moulder, S., Wheler, J. J., Janku, F., Gonzalez-Angulo, A.

Journal:

American Journal of Clinical Pathology

Year:

2015

Language:

english

File:

PDF, 809 KB

english, 2015

123

Phase 1 study of APTO-253 HCl, an inducer of KLF4, in patients with advanced or metastatic solid tumors

Cercek, Andrea, Wheler, Jennifer, Murray, Peter E., Zhou, Shawn, Saltz, Leonard

Journal:

Investigational New Drugs

Year:

2015

Language:

english

File:

PDF, 270 KB

english, 2015

124

Phase I clinical trial of lenalidomide in combination with 5-fluorouracil, leucovorin, and oxaliplatin in patients with advanced cancer

Said, Rabih, Ye, Yang, Hong, David S., Naing, Aung, Falchook, Gerald, Fu, Siqing, Wheler, Jennifer J., Piha-Paul, Sarina, Tsimberidou, Apostolia-Maria

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 604 KB

english, 2016

125

Phase I clinical trial of lenalidomide in combination with bevacizumab in patients with advanced cancer

Said, Rabih, Kakadiaris, Eugenia, Piha-Paul, Sarina, Fu, Siqing, Falchook, Gerald, Janku, Filip, Wheler, Jennifer J., Zinner, Ralph, Hong, David S., Kurzrock, Razelle, Tsimberidou, Apostolia M.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 430 KB

english, 2016

126

British Ticks

Wheler, Edward Galton

Journal:

The Journal of Agricultural Science

Year:

1906

Language:

english

File:

PDF, 3.24 MB

english, 1906

127

Cancer therapy directed by comprehensive genomic profiling: a single center study

Wheler, J. J., Janku, F., Naing, A., Li, Y., Stephen, B., Zinner, R. G., Subbiah, V., Fu, S., Karp, D. D., Falchook, G. S., Tsimberidou, A. M., Piha-Paul, S. A., Anderson, R., Ke, D., Miller, V. A., Y

Journal:

Cancer Research

Year:

2016

Language:

english

File:

PDF, 549 KB

english, 2016

128

BRAF Mutation Testing in Cell-Free DNA from the Plasma of Patients with Advanced Cancers Using a Rapid, Automated Molecular Diagnostics System

Janku, F., Huang, H. J., Claes, B., Falchook, G. S., Fu, S., Hong, D., Ramzanali, N. M., Nitti, G., Cabrilo, G., Tsimberidou, A. M., Naing, A., Piha-Paul, S. A., Wheler, J. J., Karp, D. D., Holley, V.

Journal:

Molecular Cancer Therapeutics

Year:

2016

Language:

english

File:

PDF, 550 KB

english, 2016

129

Characteristics and outcomes for patients with advanced vaginal or vulvar cancer referred to a phase I clinical trials program: the MD Anderson cancer center experience

Fu, Siqing, Shi, Naiyi, Wheler, Jennifer, Naing, Aung, Janku, Filip, Piha-Paul, Sarina, Gong, Jing, Hong, David, Tsimberidou, Apostolia, Zinner, Ralph, Subbiah, Vivek, Hou, Ming-Mo, Ramirez, Pedro, Ra

Journal:

Gynecologic Oncology Research and Practice

Year:

2015

Language:

english

File:

PDF, 749 KB

english, 2015

130

Benchmarking the Oil and Gas Industry

Miessler, Ray, Pappas, James, Wheler, Jennifer

Journal:

Year:

2012

Language:

english

File:

PDF, 647 KB

english, 2012

131

Association between new-onset hypothyroidism and clinical response in patients treated with tyrosine kinase inhibitor therapy in phase I clinical trials

Bilen, Mehmet Asim, Patel, Amy, Hess, Kenneth R., Munoz, Javier, Busaidy, Naifa L., Wheler, Jennifer J., Janku, Filip, Falchook, Gerald S., Hong, David S., Meric-Bernstam, Funda, Habra, Mouhammed Amir

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 418 KB

english, 2016

132

Dental Care in an Equal Access System Valuing Equity

Boehmer, Ulrike, Glickman, Mark, Jones, Judith A., Orner, Michelle B., Wheler, Carolyn, Berlowitz, Dan R., Kressin, Nancy R.

Journal:

Year:

2016

Language:

english

File:

PDF, 130 KB

english, 2016

133

TP53 Alterations Correlate with Response to VEGF/VEGFR Inhibitors:Implications for Targeted Therapeutics

Wheler, J. J., Janku, F., Naing, A., Li, Y., Stephen, B., Zinner, R., Subbiah, V., Fu, S., Karp, D., Falchook, G. S., Tsimberidou, A. M., Piha-Paul, S., Anderson, R., Ke, D., Miller, V., Yelensky, R.,

Journal:

Molecular Cancer Therapeutics

Year:

2016

Language:

english

File:

PDF, 282 KB

english, 2016

134

Outcomes of patients ≥65 years old with advanced cancer treated on phase I trials at MD Anderson Cancer Center

Subbiah, Ishwaria M., Wheler, Jennifer J., Hess, Kenneth R., Hong, David S., Naing, Aung, Fu, Siqing, Kurzrock, Razelle, Tsimberidou, Apostolia M.

Journal:

International Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 769 KB

english, 2016

135

Treatment of Experimental Epilepsy with Taurine

WHELER, G. H. T., OSBORNE, R. H., BRADFORD, H. F., DAVISON, A. N.

Journal:

Biochemical Society Transactions

Year:

1974

Language:

english

File:

PDF, 136 KB

english, 1974

136

Some Electrical Experiments, Chiefly Regarding the Repulsive Force of Electrical Rodies; Communicated in a Letter from Granvile Wheler, Esq; F. R. S. to Cromwell Mortimer, M. D. R. S. Secr

Granvile Wheler

Journal:

Philosophical Transactions (1665-1678)

Year:

1739-1741

Language:

english

File:

PDF, 1.36 MB

english, 1739-1741

137

1871 Inhibition of mTOR in combination with chemotherapy and angiogenic blockade shows activity in metaplastic breast cancer, an aggressive, chemo-refractory subtype of triple-negative breast cancer (TNBC)

Basho, R., Janku, F., Helgason, T., Gilcrease, M., Booser, D., Karp, D., Meric-Bernstam, F., Wheler, J., Valero, V., Albarracin, C., Litton, J., Chavez-MacGregor, M., Ibrahim, N., Murray, J., Koenig,

Journal:

European Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 69 KB

english, 2015

138

Multiplex KRAS G12/G13 Mutation Testing of Unamplified Cell-Free DNA from the Plasma of Patients with Advanced Cancers Using Droplet Digital Polymerase Chain Reaction

Janku, F., Huang, H. J., Fujii, T., Shelton, D. N., Madwani, K., Fu, S., Tsimberidou, A. M., Piha-Paul, S. A., Wheler, J. J., Zinner, R. G., Naing, A., Hong, D. S., Karp, D. D., Cabrilo, G., Kopetz, E

Journal:

Annals of Oncology

Year:

2016

Language:

english

File:

PDF, 542 KB

english, 2016

139

Immune responses to in ovo vaccine formulations containing inactivated fowl adenovirus 8b with poly[di(sodium carboxylatoethylphenoxy)]phosphazene (PCEP) and avian beta defensin as adjuvants in chickens

Sarfraz, Mishal, Suleman, Muhammed, Tikoo, Suresh K., Wheler, Colette, Potter, Andrew A., Gerdts, Volker, Dar, Arshud

Journal:

Year:

2017

Language:

english

File:

PDF, 902 KB

english, 2017

140

Neonatal pigs are susceptible to experimental Zika virus infection

Darbellay, Joseph, Lai, Kenneth, Babiuk, Shawn, Berhane, Yohannes, Ambagala, Aruna, Wheler, Colette, Wilson, Donald, Walker, Stewart, Potter, Andrew, Gilmour, Matthew, Safronetz, David, Gerdts, Volker

Journal:

Emerging Microbes & Infections

Year:

2017

Language:

english

File:

PDF, 1.20 MB

english, 2017

141

Phase I Dose‐Escalation Study of Pilaralisib (SAR245408, XL147) in Combination with Paclitaxel and Carboplatin in Patients with Solid Tumors

Wheler, Jennifer, Mutch, David, Lager, Joanne, Castell, Christelle, Liu, Li, Jiang, Jason, Traynor, Anne M.

Journal:

Year:

2017

Language:

english

File:

PDF, 506 KB

english, 2017

142

Thallium as a Reference Standard for Beta Radioactivity

A. G. Wheler Jr., S. A. Reynolds and W. A. Brooksbank Jr.

Journal:

American Water Works Association

Year:

1954

Language:

english

File:

PDF, 360 KB

english, 1954

143

A phase 2 randomised discontinuation trial of cabozantinib in patients with ovarian carcinoma

Vergote, Ignace B., Smith, David C., Berger, Raanan, Kurzrock, Razelle, Vogelzang, Nicholas J., Sella, Avishay, Wheler, Jennifer, Lee, Yihua, Foster, Paul G., Weitzman, Ron, Buckanovich, Ronald J.

Journal:

European Journal of Cancer

Year:

2017

Language:

english

File:

PDF, 543 KB

english, 2017

144

Intrauterine delivery of subunit vaccines induces a systemic and mucosal immune response in rabbits

Pasternak, Jonathan Alexander, Hamonic, Glenn, Forsberg, Nikki M., Wheler, Colette L., Dyck, Michael K., Wilson, Heather L.

Journal:

American Journal of Reproductive Immunology

Year:

2017

Language:

english

File:

PDF, 1.34 MB

english, 2017

145

Zika Virus Causes Persistent Infection in Porcine Conceptuses and may Impair Health in Offspring

Darbellay, Joseph, Cox, Brian, Lai, Kenneth, Delgado-Ortega, Mario, Wheler, Colette, Wilson, Donald, Walker, Stewart, Starrak, Gregory, Hockley, Duncan, Huang, Yanyun, Mutwiri, George, Potter, Andrew,

Journal:

Year:

2017

Language:

english

File:

PDF, 1.43 MB

english, 2017

146

Phase I study of the combination of crizotinib (as a MET inhibitor) and dasatinib (as a c-SRC inhibitor) in patients with advanced cancer

Kato, Shumei, Jardim, Denis L., Johnson, Faye M., Subbiah, Vivek, Piha-Paul, Sarina, Tsimberidou, Apostolia M., Falchook, Gerald S., Karp, Daniel, Zinner, Ralph, Wheler, Jennifer, Janku, Filip, Fu, Si

Journal:

Investigational New Drugs

Year:

2017

Language:

english

File:

PDF, 827 KB

english, 2017

147

Outcomes of patients with sarcoma enrolled in clinical trials of pazopanib combined with histone deacetylase, mTOR, Her2, or MEK inhibitors

Dembla, Vikas, Groisberg, Roman, Hess, Ken, Fu, Siqing, Wheler, Jennifer, Hong, David S., Janku, Filip, Zinner, Ralph, Piha-Paul, Sarina Anne, Ravi, Vinod, Benjamin, Robert S., Patel, Shreyaskumar, So

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.33 MB

english, 2017

148

Phase I Clinical Trial of Bendamustine and Bevacizumab for Patients With Advanced Cancer

Tsimberidou, Apostolia M., Adamopoulos, Alexandra M., Ye, Yang, Piha-Paul, Sarina, Janku, Filip, Fu, Siqing, Hong, David, Falchook, Gerald S., Naing, Aung, Wheler, Jennifer, Fortier, Adoneca, Kurzrock

Journal:

Journal of the National Comprehensive Cancer Network

Year:

2014

Language:

english

File:

PDF, 435 KB

english, 2014

149

Phase 1 dose-escalation study of anti CTLA-4 antibody ipilimumab and lenalidomide in patients with advanced cancers

Sakamuri, Divya, Glitza, Isabella C., Betancourt Cuellar, Sonia L., Subbiah, Vivek, Fu, Siqing, Tsimberidou, Apostolia M., Wheler, Jennifer J., Hong, David S., Naing, Aung, Falchook, Gerald S., Fanale

Journal:

Molecular Cancer Therapeutics

Year:

2017

Language:

english

File:

PDF, 1.27 MB

english, 2017

150

Corrigendum to “Zika Virus Causes Persistent Infection in Porcine Conceptuses and May Impair Health in Offspring”

Darbellay, Joseph, Cox, Brian, Lai, Kenneth, Delgado-Ortega, Mario, Wheler, Colette, Wilson, Donald, Walker, Stewart, Starrak, Gregory, Hockley, Duncan, Huang, Yanyun, Mutwiri, George, Potter, Andrew,

Journal:

Year:

2017

Language:

english

File:

PDF, 123 KB

english, 2017