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51

Psoriasis is associated with increased β-defensin genomic copy number

Hollox, Edward J, Huffmeier, Ulrike, Zeeuwen, Patrick L J M, Palla, Raquel, Lascorz, Jesús, Rodijk-Olthuis, Diana, van de Kerkhof, Peter C M, Traupe, Heiko, de Jongh, Gys, Heijer, Martin den

Journal:

Nature Genetics

Year:

2007

Language:

english

File:

PDF, 173 KB

english, 2007

52

Construction of a Microstructured Collagen Membrane Mimicking the Papillary Dermis Architecture and Guiding Keratinocyte Morphology and Gene Expression

Gerwen Lammers, Günter Roth, Mathias Heck, Roland Zengerle, G. Sandra Tjabringa, Elly M. Versteeg, Theo Hafmans, Ronnie Wismans, Dieter P. Reinhardt, Eugene T. P. Verwiel, Patrick L. J. M. Zeeuwen, Jo

Journal:

Macromolecular Bioscience

Year:

2012

Language:

english

File:

PDF, 827 KB

english, 2012

53

Strong induction of AIM2 expression in human epidermis in acute and chronic inflammatory skin conditions

de Koning, Heleen D., Bergboer, Judith G.M., van den Bogaard, Ellen H., van Vlijmen-Willems, Ivonne M.J.J., Rodijk-Olthuis, Diana, Simon, Anna, Zeeuwen, Patrick L.J.M., Schalkwijk, Joost

Journal:

Experimental Dermatology

Year:

2012

Language:

english

File:

PDF, 953 KB

english, 2012

54

The Effects of Human Beta-Defensins on Skin Cells in vitro

van Kilsdonk, Jeroen W.J., Jansen, Patrick A.M., van den Bogaard, Ellen H., Bos, Charlotte, Bergers, Mieke, Zeeuwen, Patrick L.J.M., Schalkwijk, Joost

Journal:

Year:

2017

Language:

english

File:

PDF, 379 KB

english, 2017

55

Phenotypical and Functional Differences in Germinative Subpopulations Derived from Normal and Psoriatic Epidermis

Franssen, Manon E J, Zeeuwen, Patrick L J M, Vierwinden, Gerty, van de Kerkhof, Peter C M, Schalkwijk, Joost, van Erp, Piet E J

Journal:

The Journal of Investigative Dermatology

Year:

2005

Language:

english

File:

PDF, 947 KB

english, 2005

56

Design of nanosecond high-voltage pulse generators

Zeeuwen, J P, Welzenis, R G van

Journal:

Journal of Physics E Scientific Instruments

Year:

1980

Language:

english

File:

PDF, 360 KB

english, 1980

57

966 The human cutaneous microbiome composition changes after coal tar treatment of both healthy and atopic dermatitis skin

Smits, J., Ederveen, T., Schalkwijk, J., van Hijum, S., Zeeuwen, P., van den Bogaard, E.

Journal:

The Journal of Investigative Dermatology

Year:

2018

Language:

english

File:

PDF, 238 KB

english, 2018

58

Induction of normal and psoriatic phenotypes in submerged keratinocyte cultures

Fred Van Ruissen, Gijs J. De Jongh, Patrick L. J. M. Zeeuwen, Piet E. J. Van Erp, Peder Madsen, Joost Schalkwijk

Journal:

Journal of Cellular Physiology

Year:

1996

Language:

english

File:

PDF, 2.73 MB

english, 1996

59

Bacteriology: Salmonella typhimurium DT104 septicaemia with meningitis in neonatal piglets

van der Wolf, P.J., Vercammen, T.J.M., Geene, J.J., van Exsel, A.C.A., Peperkamp, N.H.M.T, Voets, M.Th., Zeeuwen, A.A.P.A.

Journal:

Veterinary Quarterly

Year:

2001

Language:

english

File:

PDF, 1.03 MB

english, 2001

60

Increased Expression of Carbonic Anhydrase II (CA II) in Lesional Skin of Atopic Dermatitis: Regulation by Th2 Cytokines

Kamsteeg, Marijke, Zeeuwen, Patrick L J M, Jongh, Gys J de, Rodijk-Olthuis, Diana, Zeeuwen-Franssen, Manon E J, van Erp, Piet E J, Schalkwijk, Joost

Journal:

The Journal of Investigative Dermatology

Year:

2007

Language:

english

File:

PDF, 119 KB

english, 2007

61

Induction of skalp/elafin gene expression in cultured human keratinocytes by inflammatory cytokines

Pfundt, Rolph, van Ruissen, Fred, Zeeuwen, Patrick, Verheij, Marcel, Melchers, Diana, Geysen, Johan, Schalkwijk, Joost

Journal:

Journal of Dermatological Science

Year:

1998

Language:

english

File:

PDF, 187 KB

english, 1998

62

Drosomycin-Like Defensin, a Human Homologue of Drosophila melanogaster Drosomycin with Antifungal Activity

Simon, A., Kullberg, B. J., Tripet, B., Boerman, O. C., Zeeuwen, P., van der Ven-Jongekrijg, J., Verweij, P., Schalkwijk, J., Hodges, R., van der Meer, J. W. M., Netea, M. G.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2008

Language:

english

File:

PDF, 295 KB

english, 2008

63

Mast-cell interleukin-1β, neutrophil interleukin-17 and epidermal antimicrobial proteins in the neutrophilic urticarial dermatosis in Schnitzler's syndrome

de Koning, H.D., van Vlijmen-Willems, I.M.J.J., Rodijk-Olthuis, D., van der Meer, J.W.M., Zeeuwen, P.L.J.M., Simon, A., Schalkwijk, J.

Journal:

British Journal of Dermatology

Year:

2015

Language:

english

File:

PDF, 1.37 MB

english, 2015

64

Identification and Sequence Analysis of Two New Members of the SKALP/elafin and SPAI-2 Gene Family: BIOCHEMICAL PROPERTIES OF THE TRANSGLUTAMINASE SUBSTRATE MOTIF AND SUGGESTIONS FOR A NEW NOMENCLATURE

Zeeuwen, P. L. J. M., Hendriks, W., de Jong, W. W., Schalkwijk, J.

Journal:

Journal of Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 798 KB

english, 1997

65

Predictors of perceived stigmatization in patients with psoriasis

van Beugen, S., van Middendorp, H., Ferwerda, M., Smit, J.V., Zeeuwen-Franssen, M.E.J., Kroft, E.B.M., de Jong, E.M.G.J., Donders, A.R.T., van de Kerkhof, P.C.M, Evers, A.W.M.

Journal:

British Journal of Dermatology

Year:

2016

Language:

english

File:

PDF, 542 KB

english, 2016

66

Genetically Programmed Differences in Epidermal Host Defense between Psoriasis and Atopic Dermatitis Patients

Zeeuwen, Patrick L. J. M., de Jongh, Gys J., Rodijk-Olthuis, Diana, Kamsteeg, Marijke, Verhoosel, Renate M., van Rossum, Michelle M., Hiemstra, Pieter S., Schalkwijk, Joost, Khoury, Joseph El

Journal:

Year:

2008

Language:

english

File:

PDF, 489 KB

english, 2008

67

Recombination of hot-electrons

Rob G. van Welzenis, Jan-Pieter Zeeuwen

Journal:

Solid-State Electronics

Year:

1978

Language:

english

File:

PDF, 479 KB

english, 1978

68

Epidermal Expression of Host Response Genes upon Skin Barrier Disruption in Normal Skin and Uninvolved Skin of Psoriasis and Atopic Dermatitis Patients

de Koning, Heleen D, Kamsteeg, Marijke, Rodijk-Olthuis, Diana, van Vlijmen-Willems, Ivonne M J J, van Erp, Piet E J, Schalkwijk, Joost, Zeeuwen, Patrick L J M

Journal:

The Journal of Investigative Dermatology

Year:

2010

Language:

english

File:

PDF, 2.55 MB

english, 2010

69

Pattern Recognition Receptors in Immune Disorders Affecting the Skin

de Koning, Heleen D., Simon, Anna, Zeeuwen, Patrick L.J.M., Schalkwijk, Joost

Journal:

Journal of Innate Immunity

Year:

2012

Language:

english

File:

PDF, 553 KB

english, 2012

70

Molecular cloning of a mouse epithelial protein-tyrosine phosphatase with similarities to submembranous proteins

Dr. Wiljan Hendriks, Jan Schepens, Dietmar Bächner, Johan Rijss, Patrick Zeeuwen, Ulrich Zechner, Horst Hameister, Bé Wieringa

Journal:

Journal of Cellular Biochemistry

Year:

1995

Language:

english

File:

PDF, 1.52 MB

english, 1995

71

Transcriptional Regulation of the Elafin Gene in Human Keratinocytes

Pol, Arno, Pfundt, Rolph, Zeeuwen, Patrick, Molhuizen, Henri, Schalkwijk, Joost

Journal:

The Journal of Investigative Dermatology

Year:

2003

Language:

english

File:

PDF, 297 KB

english, 2003

72

The Biology of Cystatin M/E and its Cognate Target Proteases

Zeeuwen, Patrick L J M, Cheng, Tsing, Schalkwijk, Joost

Journal:

The Journal of Investigative Dermatology

Year:

2009

Language:

english

File:

PDF, 10.20 MB

english, 2009

73

077 Epidermal equivalents of filaggrin null keratinocytes do not show impaired skin barrier function

Niehues, H., van Vlijmen-Willems, I., Rodijk-Olthuis, D., Schalkwijk, J., van Rossum, M., Wladykowski, E., Brandner, J., van den Bogaard, E., Zeeuwen, P.

Journal:

The Journal of Investigative Dermatology

Year:

2016

Language:

english

File:

PDF, 54 KB

english, 2016

74

Colocalization of Cystatin M/E and Cathepsin V in Lamellar Granules and Corneodesmosomes Suggests a Functional Role in Epidermal Differentiation

Zeeuwen, Patrick L J M, Ishida-Yamamoto, Akemi, van Vlijmen-Willems, Ivonne M J J, Cheng, Tsing, Bergers, Mieke, Iizuka, Hajime, Schalkwijk, Joost

Journal:

The Journal of Investigative Dermatology

Year:

2006

Language:

english

File:

PDF, 552 KB

english, 2006

75

Serial analysis of gene expression in cultured human keratinocytes

Jansen, Bastiaan J.H., Zeeuwen, Patrick L.J.M., Pfundt, Rolph, Schalkwijk, Joost, van Ruissen, Fred

Journal:

Journal of Dermatological Science

Year:

1998

File:

PDF, 142 KB

1998

76

Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats

Armour, J. A. L., Palla, R., Zeeuwen, P. L. J. M., Heijer, M. d., Schalkwijk, J., Hollox, E. J.

Journal:

Nucleic Acids Research

Year:

2007

Language:

english

File:

PDF, 467 KB

english, 2007

77

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain

Hendriks, W, Schepens, J, Brugman, C, Zeeuwen, P, Wieringa, B

Journal:

Biochemical Journal

Year:

1995

Language:

english

File:

PDF, 1.52 MB

english, 1995

78

Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

de Cid, Rafael, Riveira-Munoz, Eva, Zeeuwen, Patrick L J M, Robarge, Jason, Liao, Wilson, Dannhauser, Emma N, Giardina, Emiliano, Stuart, Philip E, Nair, Rajan, Helms, Cynthia

Journal:

Nature Genetics

Year:

2009

Language:

english

File:

PDF, 414 KB

english, 2009

79

Epidermal differentiation: The role of proteases and their inhibitors

Patrick L.J.M. Zeeuwen

Journal:

European Journal of Cell Biology

Year:

2004

Language:

english

File:

PDF, 222 KB

english, 2004

80

Genetics of Psoriasis: Evidence for Epistatic Interaction between Skin Barrier Abnormalities and Immune Deviation

Bergboer, Judith G M, Zeeuwen, Patrick L J M, Schalkwijk, Joost

Journal:

The Journal of Investigative Dermatology

Year:

2012

Language:

english

File:

PDF, 1.65 MB

english, 2012

81

Purification and molecular characterization of SKALP/elafin, an elastase inhibitor with transglutaminase substrate motifs

Molhuizen, Henri O.F., Alkemade, Hans A.C., Zeeuwen, Patrick L.J.M., de Jongh, Gijs J., Wieringa, Bé, Schalkwijk, Joost

Journal:

Journal of Dermatological Science

Year:

1993

Language:

english

File:

PDF, 159 KB

english, 1993

82

Epidermal equivalents of filaggrin null keratinocytes do not show impaired skin barrier function

Niehues, Hanna, Schalkwijk, Joost, van Vlijmen-Willems, Ivonne M.J.J., Rodijk-Olthuis, Diana, van Rossum, Michelle M., Wladykowski, Ewa, Brandner, Johanna M., van den Bogaard, Ellen H.J., Zeeuwen, Pat

Journal:

Journal of Allergy and Clinical Immunology

Year:

2016

Language:

english

File:

PDF, 2.73 MB

english, 2016

83

3D skin models for 3R research: the potential of 3D reconstructed skin models to study skin barrier function

Niehues, Hanna, Bouwstra, Joke A., Waheb El Ghalbzouri, Abdoel, Brandner, Johanna M., Zeeuwen, Patrick L.J.M., van den Bogaard, Ellen H.

Journal:

Experimental Dermatology

Year:

2018

Language:

english

File:

PDF, 638 KB

english, 2018

84

189 STAT1 gain-of-function compromises skin host defense in the context of IFN-γ signaling

Niehues, H., Rösler, B., van der Krieken, D., van Vlijmen-Willems, I., Rodijk-Olthuis, D., Peppelman, M., Schalkwijk, J., Zeeuwen, P., van den Bogaard, E., van de Veerdonk, F.

Journal:

The Journal of Investigative Dermatology

Year:

2019

File:

PDF, 193 KB

2019

85

Skin microbiota in health and disease: From sequencing to biology

Ederveen, Thomas H. A., Smits, Jos P. H., Boekhorst, Jos, Schalkwijk, Joost, Bogaard, Ellen H., Zeeuwen, Patrick L. J. M.

Journal:

The Journal of Dermatology

Year:

2020

File:

PDF, 765 KB

2020

86

Cystatin M / E expression in inflammatory and neoplastic skin disorders

P.L.J.M. Zeeuwen, I.M.J.J. Van Vlijmen-Willems, H. Egami, J. Schalkwijk

Journal:

British Journal of Dermatology

Year:

2002

Language:

english

File:

PDF, 540 KB

english, 2002

87

CD26/dipeptidyl-peptidase IV in psoriatic skin: upregulation and topographical changes

R.G. Van Lingen, P.C.M. Van De Kerkhof, M.M.B. Seyger, E.M.G.J. De Jong, D.W.A. Van Rens, M.K.P. Poll, P.L.J.M. Zeeuwen, P.E.J. Van Erp

Journal:

British Journal of Dermatology

Year:

2008

Language:

english

File:

PDF, 862 KB

english, 2008

88

694 Psoriasis-associated late cornified envelope (LCE) proteins have antibacterial activity

Niehues, H., Tsoi, L.C., van der Krieken, D., Helder, R., Bouwstra, J., van den Bogaard, E., Elder, J.T., Zeeuwen, P., Schalkwijk, J.

Journal:

The Journal of Investigative Dermatology

Year:

2018

Language:

english

File:

PDF, 239 KB

english, 2018

89

191 Aryl hydrocarbon receptor controls epidermal differentiation and host defense response by regulation of AP1/AP2 transcription factor expression

Smits, J., Qu, J., Rodijk-Olthuis, D., van Vlijmen-Willems, I., Zeeuwen, P., Schalkwijk, J., Zhou, J., van den Bogaard, E.

Journal:

The Journal of Investigative Dermatology

Year:

2019

File:

PDF, 193 KB

2019

90

Cystatin M/E Is a High Affinity Inhibitor of Cathepsin V and Cathepsin L by a Reactive Site That Is Distinct from the Legumain-binding Site: A NOVEL CLUE FOR THE ROLE OF CYSTATIN M/E IN EPIDERMAL CORNIFICATION

Cheng, T., Hitomi, K., van Vlijmen-Willems, I. M. J. J., de Jongh, G. J., Yamamoto, K., Nishi, K., Watts, C., Reinheckel, T., Schalkwijk, J., Zeeuwen, P. L. J. M.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 811 KB

english, 2006

91

The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea

Zeeuwen, P. L. J. M., van Vlijmen-Willems, I. M. J. J., Cheng, T., Rodijk-Olthuis, D., Hitomi, K., Hara-Nishimura, I., John, S., Smyth, N., Reinheckel, T., Hendriks, W. J. A. J., Schalkwijk, J.

Journal:

The FASEB Journal

Year:

2010

Language:

english

File:

PDF, 974 KB

english, 2010

92

107 Filaggrin deficiency impacts cutaneous microbiota

Zeeuwen, P., Ederveen, T., van der Krieken, D., Niehues, H., Boekhorst, J., Kezic, S., Zeeuwen-Franssen, M., van Steensel, M., van Hijum, S., Schalkwijk, J.

Journal:

The Journal of Investigative Dermatology

Year:

2016

Language:

english

File:

PDF, 53 KB

english, 2016

93

Assignment of the human gene encoding the epidermal serine proteinase inhibitor SKALP (PI3) to chromosome region 20q12→q13

Molhuizen, H.O.F., Zeeuwen, P.L.J.M., Weghuis, OIde, van Kessel, Geurts, Schalkwijk, J.

Journal:

Cytogenetic and Genome Research

Year:

1994

Language:

english

File:

PDF, 659 KB

english, 1994

94

A Partial Transcriptome of Human Epidermis

Fred van Ruissen, Bastiaan J.H Jansen, Gys J de Jongh, Patrick L.J.M Zeeuwen, Joost Schalkwijk

Journal:

Year:

2002

Language:

english

File:

PDF, 173 KB

english, 2002

95

Keratolysis exfoliativa (dyshidrosis lamellosa sicca): a distinct peeling entity

Chang, Y.Y., van der Velden, J., van der Wier, G., Kramer, D., Diercks, G.F.H., van Geel, M., Coenraads, P.J., Zeeuwen, P.L.J.M., Jonkman, M.F.

Journal:

British Journal of Dermatology

Year:

2012

Language:

english

File:

PDF, 442 KB

english, 2012

96

PW03-007 - NLRP3 genetic variants in Schnitzler’s syndrome

HD De Koning,J Schalkwijk,JW van der Meer,PL Zeeuwen…

Journal:

Pediatric Rheumatology

Year:

2013

Language:

english

File:

PDF, 87 KB

english, 2013

97

Late cornified envelope (LCE) proteins: distinct expression patterns of LCE2 and LCE3 members suggest nonredundant roles in human epidermis and other epithelia

Niehues, H., van Vlijmen-Willems, I.M.J.J., Bergboer, J.G.M., Kersten, F.F.J., Narita, M., Hendriks, W.J.A.J., van den Bogaard, E.H., Zeeuwen, P.L.J.M., Schalkwijk, J.

Journal:

British Journal of Dermatology

Year:

2016

Language:

english

File:

PDF, 1014 KB

english, 2016

98

681 Aryl hydrocarbon receptor activation upregulates a battery of antimicrobial genes

Smits, J., Qu, J., Zeeuwen, P., Schalkwijk, J., Zhou, H., van den Bogaard, E.

Journal:

The Journal of Investigative Dermatology

Year:

2018

Language:

english

File:

PDF, 237 KB

english, 2018

99

An In vitro Model for Bacterial Growth on Human Stratum Corneum

Krieken, D, Ederveen, T, Hijum, S, Jansen, P, Melchers, W, Scheepers, P, Schalkwijk, J, Zeeuwen, P

Journal:

Acta Dermato Venereologica

Year:

2016

Language:

english

File:

PDF, 1.43 MB

english, 2016

100

190 Deficiency of the Human Cysteine Protease Inhibitor Cystatin M/E Causes Hypotrichosis and Dry Skin

Zeeuwen, P., van den Bogaard, E., van Geel, M., van Vlijmen-Willems, I., Jansen, P., van Erp, P., Venselaar, H., Joosten, M., Schalkwijk, J.

Journal:

The Journal of Investigative Dermatology

Year:

2019

Language:

english

File:

PDF, 193 KB

english, 2019

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