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51

Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives

Hampel, Harald, Frank, Richard, Broich, Karl, Teipel, Stefan J., Katz, Russell G., Hardy, John, Herholz, Karl, Bokde, Arun L. W., Jessen, Frank, Hoessler, Yvonne C.

Journal:

Nature Reviews Drug Discovery

Year:

2010

Language:

english

File:

PDF, 547 KB

english, 2010

52

Harn

B. Schöndorff, H. Jessen-Hansen, Ivar Bang, Matthew Steel, William J. Gies, F. G. Benedikt, V. C. Myers, W. Wiechowski, Frank P. Underhill, Israel S. Kleiner, Eduard Strauss, H. Schulz, Emil Osterber,

Journal:

Analytical and Bioanalytical Chemistry

Year:

1909

Language:

german

File:

PDF, 306 KB

german, 1909

53

A multicenter reproducibility study of single-voxel1H-MRS of the medial temporal lobe

Frank Träber, Wolfgang Block, Nikolaus Freymann, Okan Gür, Thomas Kucinski, Thilo Hammen, Gabriele Ende, Ulrich Pilatus, Harald Hampel, Hans H. Schild, Reinhard Heun, Frank Jessen

Journal:

European Radiology

Year:

2006

Language:

english

File:

PDF, 182 KB

english, 2006

54

CETP polymorphisms influence cholesterol metabolism but not Alzheimer's disease risk

Homeira Qureischie, Reinhard Heun, Dieter Lütjohann, Julius Popp, Frank Jessen, Christine Ledschbor-Frahnert, Holger Thiele, Wolfgang Maier, Frank Hentschel, Peter Kelemen, Heike Kölsch

Journal:

Year:

2008

Language:

english

File:

PDF, 230 KB

english, 2008

55

Association of SORL1 gene variants with Alzheimer's disease

Heike Kölsch, Frank Jessen, Jens Wiltfang, Piotr Lewczuk, Martin Dichgans, Stefan J. Teipel, Johannes Kornhuber, Lutz Frölich, Isabella Heuser, Oliver Peters, Birgitt Wiese, Hanna Kaduszkiewicz, Hendr

Journal:

Year:

2009

Language:

english

File:

PDF, 232 KB

english, 2009

56

Prevalence and risk factors for depression in non-demented primary care attenders aged 75 years and older

Siegfried Weyerer, Sandra Eifflaender-Gorfer, Leonore Köhler, Frank Jessen, Wolfgang Maier, Angela Fuchs, Michael Pentzek, Hanna Kaduszkiewicz, Cadja Bachmann, Matthias C. Angermeyer, Melanie Luppa, B

Journal:

Journal of Affective Disorders

Year:

2008

Language:

english

File:

PDF, 290 KB

english, 2008

57

Macrophage migration inhibitory factor in mild cognitive impairment and Alzheimer’s disease

Julius Popp, Michael Bacher, Heike Kölsch, Carmen Noelker, Oliver Deuster, Richard Dodel, Frank Jessen

Journal:

Journal of Psychiatric Research

Year:

2009

Language:

english

File:

PDF, 162 KB

english, 2009

58

Differences of cerebral activation between superior and inferior learners during motor sequence encoding and retrieval

Reinhard Heun, Nikolaus Freymann, Dirk Oliver Granath, Christian Paul Stracke, Frank Jessen, Katrin Barkow, Jürgen Reul

Journal:

Psychiatry Research: Neuroimaging

Year:

2004

Language:

english

File:

PDF, 457 KB

english, 2004

59

Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease

Stefan J. Teipel, Michael Ewers, Stefanie Wolf, Frank Jessen, Heike Kölsch, Sönke Arlt, Christian Luckhaus, Peter Schönknecht, Klaus Schmidtke, Isabella Heuser, Lutz Frölich, Gabriele Ende, Johannes P

Journal:

Psychiatry Research: Neuroimaging

Year:

2010

Language:

english

File:

PDF, 338 KB

english, 2010

60

Association of amygdala volumes with cortisol secretion in unipolar depressed patients

Anna Schuhmacher, Rainald Mössner, Frank Jessen, Lukas Scheef, Wolfgang Block, Anna Christine Belloche, Leonhard Lennertz, Hanne Welper, Susanne Höfels, Ute Pfeiffer, Michael Wagner, Wolfgang Maier, S

Journal:

Psychiatry Research: Neuroimaging

Year:

2012

Language:

english

File:

PDF, 570 KB

english, 2012

61

Multicenter stability of diffusion tensor imaging measures: A European clinical and physical phantom study

Stefan J. Teipel, Sigrid Reuter, Bram Stieltjes, Julio Acosta-Cabronero, Ulrike Ernemann, Andreas Fellgiebel, Massimo Filippi, Giovanni Frisoni, Frank Hentschel, Frank Jessen, Stefan Klöppel, Thomas M

Journal:

Psychiatry Research: Neuroimaging

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

62

Staphylococcus aureus Bacteremia in Patients with Hematological Malignancies and/or Agranulocytosis

FRANK ESPERSEN, NIELS FRIMODT-MøLLER, VIBEKE THAMDRUP ROSDAHL, OVE JESSEN, VIGGO FABER, KIRSTEN ROSENDAL

Journal:

Journal of Internal Medicine

Year:

1987

Language:

english

File:

PDF, 360 KB

english, 1987

63

RXRA gene variations influence Alzheimer's disease risk and cholesterol metabolism

Heike Kölsch, Dieter Lütjohann, Frank Jessen, Julius Popp, Frank Hentschel, Peter Kelemen, Silvia Friedrichs, T.A. Wolfgang Maier, Reinhard Heun

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 487 KB

english, 2009

64

Alterations of cholesterol precursor levels in Alzheimer's disease

Heike Kölsch, Reinhard Heun, Frank Jessen, Julius Popp, Frank Hentschel, Wolfgang Maier, Dieter Lütjohann

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 225 KB

english, 2010

65

The effects of operative indication and urgency of intervention on patient outcomes after thoracic aortic endografting

Martyn Knowles, Erin H. Murphy, J. Michael Dimaio, J. Gregory Modrall, Carlos H. Timaran, Michael E. Jessen, Frank R. Arko III

Journal:

Journal of Vascular Surgery

Year:

2011

Language:

english

File:

PDF, 998 KB

english, 2011

66

Volumetric analysis of type B aortic dissections treated with thoracic endovascular aortic repair

Gregory A. Stanley, Erin H. Murphy, Martyn Knowles, Mihaila Ilves, Michael E. Jessen, J. Michael Dimaio, J. Gregory Modrall, Frank R. Arko III

Journal:

Journal of Vascular Surgery

Year:

2011

Language:

english

File:

PDF, 1023 KB

english, 2011

67

PPARD haplotype influences cholesterol metabolism but is no risk factor of Alzheimer's disease

Julia Holzapfel, Reinhard Heun, Dieter Lütjohann, Frank Jessen, Wolfgang Maier, Heike Kölsch

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

68

Smoking upregulates α4β2* nicotinic acetylcholine receptors in the human brain

Ullrich Wüllner, Daniela Gündisch, Hans Herzog, Martina Minnerop, Alexis Joe, Marc Warnecke, Frank Jessen, Christian Schütz, Michael Reinhardt, Wolfgang Eschner, Thomas Klockgether, Joern Schmaljohann

Journal:

Neuroscience Letters

Year:

2008

Language:

english

File:

PDF, 286 KB

english, 2008

69

Influence of SORL1 gene variants: Association with CSF amyloid-β products in probable Alzheimer's disease

Heike Kölsch, Frank Jessen, Jens Wiltfang, Piotr Lewczuk, Martin Dichgans, Johannes Kornhuber, Lutz Frölich, Isabella Heuser, Oliver Peters, Jörg B. Schulz, Sibylle G. Schwab, Wolfgang Maier

Journal:

Neuroscience Letters

Year:

2008

Language:

english

File:

PDF, 137 KB

english, 2008

70

Mild cognitive impairment (MCI) and actual retrieval performance affect cerebral activation in the elderly

Reinhard Heun, Katrin Freymann, Michael Erb, Dirk T. Leube, Frank Jessen, Tilo T. Kircher, Wolfgang Grodd

Journal:

Neurobiology of Aging

Year:

2007

Language:

english

File:

PDF, 641 KB

english, 2007

71

Volume reduction of the entorhinal cortex in subjective memory impairment

Frank Jessen, Ludger Feyen, Katrin Freymann, Ralf Tepest, Wolfgang Maier, Reinhard Heun, Hans-H. Schild, Lukas Scheef

Journal:

Neurobiology of Aging

Year:

2006

Language:

english

File:

PDF, 293 KB

english, 2006

72

Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: A multicenter study

Piotr Lewczuk, Johannes Kornhuber, Hugo Vanderstichele, Eugeen Vanmechelen, Hermann Esselmann, Mirko Bibl, Stefanie Wolf, Markus Otto, Udo Reulbach, Heike Kölsch, Frank Jessen, Johannes Schröder, Pete

Journal:

Neurobiology of Aging

Year:

2008

Language:

english

File:

PDF, 497 KB

english, 2008

73

CSF cortisol in Alzheimer's disease and mild cognitive impairment

Julius Popp, Karsten Schaper, Heike Kölsch, Gabriela Cvetanovska, Fatima Rommel, Dietrich Klingmüller, Richard Dodel, Ullrich Wüllner, Frank Jessen

Journal:

Neurobiology of Aging

Year:

2009

Language:

english

File:

PDF, 118 KB

english, 2009

74

Nitration of Tyrosine 10 Critically Enhances Amyloid β Aggregation and Plaque Formation

Markus P. Kummer, Michael Hermes, Andrea Delekarte, Thea Hammerschmidt, Sathish Kumar, Dick Terwel, Jochen Walter, Hans-Christian Pape, Simone König, Sigrun Roeber, Frank Jessen, Thomas Klockgether, M

Journal:

Year:

2011

Language:

english

File:

PDF, 1.61 MB

english, 2011

75

The future of Alzheimer's disease: The next 10 years

Harald Hampel, David Prvulovic, Stefan Teipel, Frank Jessen, Christian Luckhaus, Lutz Frölich, Matthias W. Riepe, Richard Dodel, Thomas Leyhe, Lars Bertram, Wolfgang Hoffmann, Frank Faltraco

Journal:

Progress in Neurobiology

Year:

2011

Language:

english

File:

PDF, 396 KB

english, 2011

76

Regional 1H-MR-spectroscopy with respect to the theoretical distribution of neuropathology in AD patients

Frank Jessen, Wolfgang Block, Frank Traeber, Reinhard Heun, Ewald Keller, Andreas Papassotiropoulos, Rolf Lamerichs, Hans H. Schild

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 190 KB

english, 2000

77

Plasma 24S-hydroxycholesterol (cerebrosterol): An indicator of neuronal degeneration and potential state marker for dementia

Andreas Papassotiropoulos, Dieter Lutjohann, Metin Bagli, Sandra Locatelli, Frank Jessen, Marie Luise Rao, Wolfgang Maier, Klaus von Bergmann

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 151 KB

english, 2000

78

Association between an interleukin-6 promoter and 3′ flanking region haplotype and reduced Alzheimer's disease risk in a German population

Metin Bagli, Andreas Papassotiropoulos, Michael Knapp, Frank Jessen, Marie Luise Rao, Wolfgang Maier, Reinhard Heun

Journal:

Neuroscience Letters

Year:

2000

Language:

english

File:

PDF, 87 KB

english, 2000

79

Allelic association between the D10S1423 marker and Alzheimer's disease in a German population

Michael Majores, Metin Bagli, Andreas Papassotiropoulos, Sybille G Schwab, Frank Jessen, Marie Luise Rao, Wolfgang Maier, Reinhard Heun

Journal:

Neuroscience Letters

Year:

2000

Language:

english

File:

PDF, 75 KB

english, 2000

80

Amplitude reduction of the mismatch negativity in first-degree relatives of patients with schizophrenia

Frank Jessen, Thomas Fries, Claudia Kucharski, Tsuneko Nishimura, Klaus Hoenig, Wolfgang Maier, Peter Falkai, Reinhard Heun

Journal:

Neuroscience Letters

Year:

2001

Language:

english

File:

PDF, 96 KB

english, 2001

81

Genetic polymorphism of cathepsin D is strongly associated with the risk for developing sporadic Alzheimer's disease

Andreas Papassotiropoulos, Metin Bagli, Oliver Feder, Frank Jessen, Wolfgang Maier, Marie Luise Rao, Michael Ludwig, Sibylle G Schwab, Reinhard Heun

Journal:

Neuroscience Letters

Year:

1999

Language:

english

File:

PDF, 62 KB

english, 1999

82

Activation of human language processing brain regions after the presentation of random letter strings demonstrated with event-related functional magnetic resonance imaging

Frank Jessen, Michael Erb, Uwe Klose, Martin Lotze, Wolfgang Grodd, Reinhard Heun

Journal:

Neuroscience Letters

Year:

1999

Language:

english

File:

PDF, 653 KB

english, 1999

83

Response-related fMRI analysis during encoding and retrieval revealed differences in cerebral activation by retrieval success

Reinhard Heun, Frank Jessen, Uwe Klose, Michael Erb, Dirk-Oliver Granath, Wolfgang Grodd

Journal:

Psychiatry Research: Neuroimaging

Year:

2000

Language:

english

File:

PDF, 2.88 MB

english, 2000

84

Encoding and retrieval related cerebral activation in continuous verbal recognition

Frank Jessen, Sebastian Flacke, Dirk-Oliver Granath, Christoph Manka, Lukas Scheef, Andreas Papassotiropoulos, Hans H Schild, Reinhard Heun

Journal:

Cognitive Brain Research

Year:

2001

Language:

english

File:

PDF, 707 KB

english, 2001

85

Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease

Julius Popp, Piotr Lewczuk, Heike Kölsch, Sabrina Meichsner, Wolfgang Maier, Johannes Kornhuber, Frank Jessen, Dieter Lütjohann

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 264 KB

english, 2012

86

DNA sequence variants of the FKBP5 gene are associated with unipolar depression

Zobel, Astrid, Schuhmacher, Anna, Jessen, Frank, Höfels, Susanne, von Widdern, Olrik, Metten, Martin, Pfeiffer, Ute, Hanses, Claudia, Becker, Tim, Rietschel, Marcella, Scheef, Lukas, Block, Wolfgang,

Journal:

The International Journal of Neuropsychopharmacology

Year:

2010

Language:

english

File:

PDF, 125 KB

english, 2010

87

Hybrid Endovascular Treatment of an Anomalous Right Subclavian Artery Dissection in a Patient With Marfan Syndrome

Gregory A. Stanley, Frank R. Arko III, Mazin I. Foteh, Michael E. Jessen, J. Michael DiMaio

Journal:

The Annals of Thoracic Surgery

Year:

2012

Language:

english

File:

PDF, 733 KB

english, 2012

88

Response-related fMRI of veridical and false recognition of words

Reinhard Heun, Frank Jessen, Uwe Klose, Michael Erb, Dirk-Oliver Granath, Wolfgang Grodd

Journal:

European Psychiatry

Year:

2004

Language:

english

File:

PDF, 511 KB

english, 2004

89

CYP46A1 variants influence Alzheimer's disease risk and brain cholesterol metabolism

Heike Kölsch, Dieter Lütjohann, Frank Jessen, Julius Popp, Frank Hentschel, Peter Kelemen, Sandra Schmitz, Wolfgang Maier, Reinhard Heun

Journal:

European Psychiatry

Year:

2009

Language:

english

File:

PDF, 361 KB

english, 2009

90

P2-153: Alterations of brain cholesterol metabolism: Relevance of desmosterol in Alzheimer’s disease and vascular dementia

Heike Kölsch, Reinhard Heun, Frank Jessen, Julius Popp, Wolfgang Maier, Dieter Lütjohann

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 58 KB

english, 2006

91

P-129: Cognitive performance and grey matter structure in elderly with subjective memory impairment

Frank Jessen, Lukas Scheef, Karsten Schaper, Michael Wagner

Journal:

Alzheimer's & Dementia

Year:

2007

Language:

english

File:

PDF, 48 KB

english, 2007

92

IC-P2-105: A multicenter 1H-MRS study of the medial temporal lobe in Alzheimer's disease and mild cognitive impairment

Frank Jessen, Okan Gür, Wolfgang Block, Gabriele Ende, Lutz Frölich, Holger Jahn, Jens Wiltfang, Johannes Kornhuber, Frank Träber

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 110 KB

english, 2008

93

IC-P2-141: Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease: A longitudinal study

Stefan J. Teipel, Michael Ewers, Stephanie Wolf, Frank Jessen, Oliver Peters, Christine Born, Johannes Kornhuber, Harald Hampel

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 143 KB

english, 2008

94

P1-252: A multicenter 1H-MRS study of the medial temporal lobe in Alzheimer's disease and mild cognitive impairment

Frank Jessen, Okan Gür, Wolfgang Block, Gabriele Ende, Lutz Frölich, Holger Jahn, Jens Wiltfang, Johannes Kornhuber, Frank Träber

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 52 KB

english, 2008

95

Correlation of CSF biomarkers with 1H-MRS metabolites of the medial temporal lobe in Alzheimer's Disease

Frank Jessen, Frank Träber, Wolfgang Block, Okan Gür, Lutz Frölich, Gabriele Ende, Thilo Hammen, Thomas Kucinski, Holger Jahn, Johannes Kornhuber, Piotr Lewczuk, Jens Wiltfang

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 100 KB

english, 2009

96

Evidence for neuronal compensation during episodic memory in subjective memory impairment

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 46 KB

english, 2011

97

Glucose metabolism, gray matter structure and memory decline in subjective memory impairment

Michael Wagner, Frank Jessen, Lukas Scheef

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

98

CSF biomarkers and disease progression in an interrupted MCI trial

Oliver Peters, Lisa Katharina Joachim, Klaus Schmidtke, Michael Hüll, Eckart Rüther, Stefan Teipel, Hans-Jürgen Möller, Frank Jessen, Christian Luckhaus, Wolfgang Maier, Jens Wiltfang, Johannes Kornhu

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 106 KB

english, 2012

99

Volumetric Analysis of the Thoracic Aorta in Type B Dissection Treated with TEVAR

Gregory A. Stanley, Martyn Knowles, Erin H. Murphy, Mihaila Ilves, Carlos H. Timaran, Michael Jessen, J. Michael Dimaio, Frank R. Arko

Journal:

Journal of Vascular Surgery

Year:

2010

Language:

english

File:

PDF, 180 KB

english, 2010

100

Proton magnetic resonance spectroscopy in subjects at risk for schizophrenia

Frank Jessen, Harald Scherk, Frank Träber, Sonja Theyson, Julia Berning, Ralf Tepest, Peter Falkai, Hans-H. Schild, Wolfgang Maier, Michael Wagner, Wolfgang Block

Journal:

Schizophrenia Research

Year:

2006

Language:

english

File:

PDF, 193 KB

english, 2006