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1

FOUR DEATHS AND A FUNERAL: FROM CASPASES TO ALTERNATIVE MECHANISMS

Leist, Marcel, Jäättelä, Marja

Journal:

Nature Reviews Molecular Cell Biology

Year:

2001

Language:

english

File:

PDF, 715 KB

english, 2001

2

Heat shock proteins as cellular lifeguards

Jäättelä, Marja

Journal:

Annals of Medicine

Year:

1999

Language:

english

File:

PDF, 1.14 MB

english, 1999

3

Connecting Hsp70, sphingolipid metabolism and lysosomal stability

Petersen, Nikolaj H.T., Kirkegaard, Thomas, Olsen, Ole Dines, Jäättelä, Marja

Journal:

Year:

2010

Language:

english

File:

PDF, 932 KB

english, 2010

4

Cell death induced by TNF or serum starvation is independent of ErbB receptor signaling in MCF-7 breast carcinoma cells

Mikala Egeblad, Marja Jäättelä

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 216 KB

english, 2000

5

Heat shock protects WEHI-164 target cells from the cytolysis by tumor necrosis factors α and β

Marja Jäättelä, Kalle Saksela, Eero Saksela

Journal:

European Journal of Immunology

Year:

1989

Language:

english

File:

PDF, 804 KB

english, 1989

6

Sensitization to TNF-induced apoptosis by 1,25-dihydroxy vitamin D3 involves up-regulation of the TNF receptor 1 and cathepsin B

Ida Stenfeldt Mathiasen, Christina Mørk Hansen, Lasse Foghsgaard, Marja Jäättelä

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 171 KB

english, 2001

7

Truncated ErbB2 receptor enhances ErbB1 signaling and induces reversible, ERK-independent loss of epithelial morphology

Mikala Egeblad, Ole H. Mortensen, Marja Jäättelä

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 371 KB

english, 2001

8

A sub-set of immediate early mRNAs induced by tumor necrosis factor-α during cellular cytotoxic and non-cytotoxic responses

Juha Klefstrom, Eero Saksela, Kari Alitalo, Päivi J. Koskinen, Marja Jäättelä, Rodrigo Bravo

Journal:

International Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 740 KB

english, 1993

9

Over-expression of hsp70 confers tumorigenicity to mouse fibrosarcoma cells

Marja Jäättelä

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 617 KB

english, 1995

10

ErbB2-associated changes in the lysosomal proteome

Jesper Nylandsted, Andrea C. Becker, Jakob Bunkenborg, Jens S. Andersen, Jörn Dengjel, Marja Jäättelä

Journal:

Year:

2011

Language:

english

File:

PDF, 424 KB

english, 2011

11

Lack of neuroprotection by heat shock protein 70 overexpression in a mouse model of global cerebral ischemia

Tomas Olsson, Oskar Hansson, Jesper Nylandsted, Marja Jäättelä, Maj-Lis Smith, Tadeusz Wieloch

Journal:

Experimental Brain Research

Year:

2004

Language:

english

File:

PDF, 520 KB

english, 2004

12

Inhibitors of cysteine cathepsin and calpain do not prevent ultraviolet-B-induced apoptosis in human keratinocytes and HeLa cells

Bo Bang, Ole Baadsgaard, Lone Skov, Marja Jäättelä

Journal:

Archives of Dermatological Research

Year:

2004

Language:

english

File:

PDF, 437 KB

english, 2004

13

Apoptosis and autophagy: Targeting autophagy signalling in cancer cells –‘trick or treats’?

Elisabeth A. Corcelle, Pietri Puustinen, Marja Jäättelä

Journal:

Year:

2009

Language:

english

File:

PDF, 746 KB

english, 2009

14

Heat Shock Protein 70 Is Required for the Survival of Cancer Cells

JESPER NYLANDSTED, KARSTEN BRAND, MARJA JÄÄTTELÄ

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 400 KB

english, 2000

15

TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells

Herrero-Martín, Griselda, Høyer-Hansen, Maria, García-García, Celina, Fumarola, Claudia, Farkas, Thomas, López-Rivas, Abelardo, Jäättelä, Marja

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 139 KB

english, 2009

16

TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells

Herrero-Martín, Griselda, Høyer-Hansen, Maria, García-García, Celina, Fumarola, Claudia, Farkas, Thomas, López-Rivas, Abelardo, Jäättelä, Marja

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 722 KB

english, 2009

17

Cytosolic FoxO1: alive and killing

Medema, René H., Jäättelä, Marja

Journal:

Nature Cell Biology

Year:

2010

Language:

english

File:

PDF, 172 KB

english, 2010

18

Heat-shock protein 70 antagonizes apoptosis-inducing factor

Garrido, Carmen, Ravagnan, Luigi, Gurbuxani, Sandeep, Susin, Santos A., Maisse, Carine, Daugas, Eric, Zamzami, Naoufal, Mak, Tak, Jäättelä, Marja, Penninger, Josef M.

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 551 KB

english, 2001

19

Caspase-independent cell death in T lymphocytes

Jäättelä, Marja, Tschopp, Jürg

Journal:

Nature Immunology

Year:

2003

Language:

english

File:

PDF, 2.87 MB

english, 2003

20

Burning up TNF toxicity for cancer therapy

Leist, Marcel, Jäättelä, Marja

Journal:

Nature Medicine

Year:

2002

Language:

english

File:

PDF, 91 KB

english, 2002

21

Lysosomes and autophagy in cell death control

Kroemer, Guido, Jäättelä, Marja

Journal:

Nature Reviews Cancer

Year:

2005

Language:

english

File:

PDF, 603 KB

english, 2005

22

Selective depletion of inducible HSP70 enhances immunogenicity of rat colon cancer cells

Gurbuxani, Sandeep, Bruey, Jean-Marie, Fromentin, Annie, Larmonier, Nicolas, Parcellier, Arnaud, Jäättelä, Marja, Martin, François, Solary, Eric, Garrido, Carmen

Journal:

Year:

2001

Language:

english

File:

PDF, 367 KB

english, 2001

23

E2F activity is essential for survival of Myc-overexpressing human cancer cells

Santoni-Rugiu, Eric, Duro, Dominique, Farkas, Thomas, Mathiasen, Ida S, Jäättelä, Marja, Bartek, Jiri, Lukas, Jiri

Journal:

Year:

2002

Language:

english

File:

PDF, 229 KB

english, 2002

24

Multiple cell death pathways as regulators of tumour initiation and progression

Jäättelä, Marja

Journal:

Year:

2004

Language:

english

File:

PDF, 218 KB

english, 2004

25

Acquired antiestrogen resistance in MCF-7 human breast cancer sublines is not accomplished by altered expression of receptors in the ErbB-family

Søren S. Larsen, Mikala Egeblad, Marja Jäättelä, Anne E. Lykkesfeldt

Journal:

Breast Cancer Research and Treatment

Year:

1999

Language:

english

File:

PDF, 322 KB

english, 1999

26

Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases

Jäättelä, Marja, Wissing, Dorte, Kokholm, Klaus, Kallunki, Tuula, Egeblad, Mikala

Journal:

The EMBO Journal

Year:

1998

Language:

english

File:

PDF, 684 KB

english, 1998

27

Lysosomal involvement in cell death and cancer

Thomas Kirkegaard, Marja Jäättelä

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2009

Language:

english

File:

PDF, 871 KB

english, 2009

28

Overexpression of heat shock protein 70 in R6/2 Huntington’s disease mice has only modest effects on disease progression

Oskar Hansson, Jesper Nylandsted, Roger F. Castilho, Marcel Leist, Marja Jäättelä, Patrik Brundin

Journal:

Year:

2003

Language:

english

File:

PDF, 1.44 MB

english, 2003

29

Cell death induced by down-regulation of heat shock protein 70 in lung cancer cell lines is p53-independent and does not require DNA cleavage

Steffen Frese, Manuela Schaper, Jan-Rasmus Kuster, Daniela Miescher, Marja Jäättelä, Thomas Buehler, Ralph A Schmid

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2003

Language:

english

File:

PDF, 265 KB

english, 2003

30

TNF-Induced Mitochondrial Changes and Activation of Apoptotic Proteases are Inhibited by A20

Dorte Wissing, Helle Mouritzen, Marja Jäättelä

Journal:

Free Radical Biology and Medicine

Year:

1998

Language:

english

File:

PDF, 246 KB

english, 1998

31

microRNA-101 is a potent inhibitor of autophagy

Frankel, Lisa B, Wen, Jiayu, Lees, Michael, Høyer-Hansen, Maria, Farkas, Thomas, Krogh, Anders, Jäättelä, Marja, Lund, Anders H

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 1.30 MB

english, 2011

32

HSP70 Overexpression Mediates the Escape of a Doxorubicin-Induced G2 Cell Cycle Arrest

Jan Karlseder, Dorte Wissing, Gerhard Holzer, Lukas Orel, Gerhard Sliutz, Herbert Auer, Marja Jäättelä, Manuel M. Simon

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 96 KB

english, 1996

33

BIBX1382BS, but Not AG1478 or PD153035, Inhibits the ErbB Kinases at Different Concentrations in Intact Cells

Mikala Egeblad, Ole H. Mortensen, Léon C.L.T. van Kempen, Marja Jäättelä

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 312 KB

english, 2001

34

In Vivo and in Vitro Evidence for Extracellular Caspase Activity Released from Apoptotic Cells

Hannes Hentze, Frank Schwoebel, Søren Lund, Marius Kehl, Wolfgang Ertel, Albrecht Wendel, Marja Jäättelä, Marcel Leist

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 98 KB

english, 2001

35

In Vivo and in Vitro Evidence for Extracellular Caspase Activity Released from Apoptotic Cells: Volume 283, Number 5 (2001), pages 1111–1117

Hannes Hentze, Frank Schwoebel, Søren Lund, Marius Kehl, Wolfgang Ertel, Albrecht Wendel, Marja Jäättelä, Marcel Leist

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

File:

PDF, 12 KB

2001

36

Escaping Cell Death: Survival Proteins in Cancer

Marja Jäättelä

Journal:

Experimental Cell Research

Year:

1999

Language:

english

File:

PDF, 197 KB

english, 1999

37

Heat shock protein hsp70 overexpression confers resistance against nitric oxide

Kerstin Bellmann, Marja Jäättelä, Dorte Wissing, Volker Burkart, Hubert Kolb

Journal:

Year:

1996

Language:

english

File:

PDF, 533 KB

english, 1996

38

Activation of phospholipase A2 by Hsp70 in vitro

Ajay K. Mahalka, Christian Code, Behnam Rezaijahromi, Thomas Kirkegaard, Marja Jäättelä, Paavo K.J. Kinnunen

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2011

Language:

english

File:

PDF, 307 KB

english, 2011

39

Anticancer agent CHS-828 inhibits cellular synthesis of NAD

Uffe Høgh Olesen, Mette Knak Christensen, Fredrik Björkling, Marja Jäättelä, Peter Buhl Jensen, Maxwell Sehested, Søren Jensby Nielsen

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 675 KB

english, 2008

40

Continuous interferon-γ or tumor necrosis factor-α exposure of enterocytes attenuates cell death responses

Jakob B Seidelin, Marja Jäättelä, Ole Haagen Nielsen

Journal:

Year:

2004

Language:

english

File:

PDF, 222 KB

english, 2004

41

Autophagy as a basis for the health-promoting effects of vitamin D

Maria Høyer-Hansen, Sasja Pauline Schultz Nordbrandt, Marja Jäättelä

Journal:

Trends in Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 257 KB

english, 2010

42

Triggering caspase-independent cell death to combat cancer

Ida S Mathiasen, Marja Jäättelä

Journal:

Trends in Molecular Medicine

Year:

2002

Language:

english

File:

PDF, 1.82 MB

english, 2002

43

IFNB1/interferon-β-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function

Ambjørn, Malene, Ejlerskov, Patrick, Liu, Yawei, Lees, Michael, Jäättelä, Marja, Issazadeh-Navikas, Shohreh

Journal:

Year:

2013

Language:

english

File:

PDF, 2.93 MB

english, 2013

44

The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions

Mads Daugaard, Mikkel Rohde, Marja Jäättelä

Journal:

Year:

2007

Language:

english

File:

PDF, 1023 KB

english, 2007

45

Combating apoptosis and multidrug resistant cancers by targeting lysosomes

Groth-Pedersen, Line, Jäättelä, Marja

Journal:

Year:

2013

Language:

english

File:

PDF, 459 KB

english, 2013

46

Human heat shock protein 70 (Hsp70) as a peripheral membrane protein

Mahalka, Ajay K., Kirkegaard, Thomas, Jukola, Laura T.I., Jäättelä, Marja, Kinnunen, Paavo K.J.

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2014

Language:

english

File:

PDF, 2.59 MB

english, 2014

47

S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells

Jaiswal, Jyoti K., Lauritzen, Stine P., Scheffer, Luana, Sakaguchi, Masakiyo, Bunkenborg, Jakob, Simon, Sanford M., Kallunki, Tuula, Jäättelä, Marja, Nylandsted, Jesper

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 5.10 MB

english, 2014

48

Corrigendum to “Activation of phospholipase A2 by Hsp70 in vitro” [Biochim. Biophys. Acta 1808 (2011) 2569–2572]

Mahalka, Ajay K., Code, Christian, Jahromi, Behnam Rezai, Kirkegaard, Thomas, Jäättelä, Marja, Kinnunen, Paavo K.J.

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2014

Language:

english

File:

PDF, 117 KB

english, 2014

49

Tumor necrosis factor-α and interferon-γ inhibit insulin-like growth factor II gene expression in human fetal adrenal cell cultures

Ilvesmäki, Vesa, Jäättelä, Marja, Saksela, Eero, Voutilainen, Raimo

Journal:

Molecular and Cellular Endocrinology

Year:

1993

Language:

english

File:

PDF, 839 KB

english, 1993

50

Involvement of Caspase-Dependent Activation of Cytosolic Phospholipase A2in Tumor Necrosis Factor-Induced Apoptosis

Dorte Wissing, Helle Mouritzen, Mikala Egeblad, Guy G. Poirier and Marja Jäättelä

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.01 MB

english, 1997

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