Jan J. Sciciński: search on Z-Library

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1

Follow the ATP: Tumor Energy Production: A Perspective

Oronsky, Bryan, Oronsky, Neil, Fanger, Gary, Parker, Christopher, Caroen, Scott, Lybeck, Michelle, Scicinski, Jan

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 786 KB

english, 2014

2

Six Degrees of Separation: The Oxygen Effect in the Development of Radiosensitizers

Oronsky, Bryan T., Knox, Susan J., Scicinski, Jan

Journal:

Translational Oncology

Year:

2011

Language:

english

File:

PDF, 290 KB

english, 2011

3

The development of a ‘safety-catch’ arylgermane for biaryl synthesis by palladium-catalysed germyl-stille cross-coupling

Alan C. Spivey, Christopher J. G. Gripton, Joseph P. Hannah, Chih-Chung Tseng, Paul de Fraine, Nigel J. Parr, Jan J. Scicinski

Journal:

Applied Organometallic Chemistry

Year:

2007

Language:

english

File:

PDF, 360 KB

english, 2007

4

Rapid One-Pot Preparation of 2-Substituted Benzimidazoles from 2-Nitroanilines Using Microwave Conditions.

David S. VanVliet, Paul Gillespie, Jan J. Scicinski

Journal:

Year:

2006

File:

PDF, 18 KB

2006

5

Rapid one-pot preparation of 2-substituted benzimidazoles from 2-nitroanilines using microwave conditions

David S. VanVliet, Paul Gillespie, Jan J. Scicinski

Journal:

Tetrahedron Letters

Year:

2005

Language:

english

File:

PDF, 97 KB

english, 2005

6

Is Nitric Oxide (NO) the Last Word in Radiosensitization? A Review

Oronsky, Bryan T., Knox, Susan J., Scicinski, Jan J.

Journal:

Translational Oncology

Year:

2012

Language:

english

File:

PDF, 188 KB

english, 2012

7

RRx-001: a systemically non-toxic M2-to-M1 macrophage stimulating and prosensitizing agent in Phase II clinical trials

Oronsky, Bryan, Paulmurugan, Ramasamy, Foygel, Kira, Scicinski, Jan, Knox, Susan J., Peehl, Donna, Zhao, Hongjuan, Ning, Shoucheng, Cabrales, Pedro, Summers, Thomas A., Reid, Tony R., Fitch, William L

Journal:

Expert Opinion on Investigational Drugs

Year:

2017

Language:

english

File:

PDF, 1.15 MB

english, 2017

8

Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders || Cancer and Beyond: Discovery and Development of NO-Releasing Therapeutics

Year:

2019

Language:

english

File:

PDF, 2.65 MB

english, 2019

9

Going viral: a review of replication-selective oncolytic adenoviruses

Larson, Christopher, Oronsky, Bryan, Scicinski, Jan, Fanger, Gary R., Stirn, Meaghan, Oronsky, Arnold, Reid, Tony R.

Journal:

Year:

2015

Language:

english

File:

PDF, 974 KB

english, 2015

10

Analysis of Solid-Phase Reactions: Product Identification and Quantification by Use of UV-Chromophore-Containing Dual-Linker Analytical Constructs

Geoff M. Williams, Robin A. E. Carr, Miles S. Congreve, Corinne Kay, Stephen C. McKeown, Peter J. Murray, Jan J. Scicinski, Stephen P. Watson

Journal:

Angewandte Chemie

Year:

2000

Language:

english

File:

PDF, 104 KB

english, 2000

11

Analytical Construct Resins for Analysis of Solid-Phase Chemistry

Miles S. Congreve, Steven V. Ley, Jan J. Scicinski

Journal:

Chemistry - A European Journal

Year:

2002

Language:

english

File:

PDF, 250 KB

english, 2002

12

Analysis of Solid-Phase Reactions: Product Identification and Quantification by Use of UV-Chromophore-Containing Dual-Linker Analytical Constructs

Geoff M. Williams, Robin A. E. Carr, Miles S. Congreve, Corinne Kay, Stephen C. McKeown, Peter J. Murray, Jan J. Scicinski, Stephen P. Watson

Journal:

Angewandte Chemie International Edition

Year:

2000

Language:

english

File:

PDF, 191 KB

english, 2000

13

ChemInform Abstract: Clean Synthesis of α-Bromo Ketones and Their Utilization in the Synthesis of 2-Alkoxy-2,3-dihydro-2-aryl-1,4-benzodioxanes, 2-Amino-4-aryl-1,3-thiazoles, and Piperidino-2-amino-1,3-thiazoles Using Polymer-Supported Reagents.

Joerg Habermann, Steven V. Ley, Jan J. Scicinski, James S. Scott, Andrew W. Thomas

Journal:

Year:

2000

File:

PDF, 37 KB

2000

14

ChemInform Abstract: Analytical Construct Resins for Analysis of Solid-Phase Chemistry

Miles S. Congreve, Steven V. Ley, Jan J. Scicinski

Journal:

Year:

2002

File:

PDF, 25 KB

2002

15

ChemInform Abstract: Identification of Potent and Selective Oxytocin Antagonists. Part 1. Indole and Benzofuran Derivatives.

Paul G. Wyatt, Michael J. Allen, Josie Chilcott, Alison Foster, David G. Livermore, Jackie E. Mordaunt, Jan Scicinski, Patrick M. Woollard

Journal:

Year:

2002

File:

PDF, 31 KB

2002

16

Microwave-Assisted Saccharide Coupling with n-Pentenyl Glycosyl Donors.

Felix Mathew, K. N. Jayaprakash, Bert Fraser-Reid, Jessy Mathew, Jan Scicinski

Journal:

Year:

2004

File:

PDF, 101 KB

2004

17

Microwave-assisted saccharide coupling with n-pentenyl glycosyl donors

Felix Mathew, K.N. Jayaprakash, Bert Fraser-Reid, Jessy Mathew, Jan Scicinski

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 318 KB

english, 2003

18

Versatile solid-phase synthesis of secondary amines from alcohols. Development of an N-Boc-(o-nitrobenzene)sulfonamide linker

Miles S. Congreve, Corinne Kay, Jan J. Scicinski, Steven V. Ley, Geoffrey Williams, Peter J. Murray, Stephen C. McKeown, Stephen P. Watson

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 256 KB

english, 2003

19

The squalestatins: Synthesis of c-4 carboxamide derivatives

Chuen Chan, Jan J Scicinski, Anton Rp Srikantha, Nigel S Watson

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 291 KB

english, 1996

20

Rapid reaction scanning of solid phase chemistry using resins incocorporating analytical constructs

Peter John Murray, Corinne Kay, Jan J. Sciciński, Stephen C. McKeown, Stephen P. Watson, Robin A.E. Carr

Journal:

Tetrahedron Letters

Year:

1999

Language:

english

File:

PDF, 247 KB

english, 1999

21

Identification of potent and selective oxytocin antagonists. Part 1: indole and benzofuran derivatives

Paul G Wyatt, Michael J Allen, Josie Chilcott, Alison Foster, David G Livermore, Jackie E Mordaunt, Jan Scicinski, Patrick M Woollard

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 171 KB

english, 2002

22

Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamides

Paul W. Smith, Steven L. Sollis, Peter D. Howes, Peter C. Cherry, Kevin N. Cobley, Helen Taylor, Andrew R. Whittington, Jan Scicinski, Richard C. Bethell, Neil Taylor, Tadeusz Skarzynski, Anne Cleasby

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 289 KB

english, 1996

23

The solid phase synthesis of a series of tri-substituted hydantoin ligands for the somatostatin SST5 receptor

Jan J. Sciciński, Michael D. Barker, Peter John Murray, Emma M. Jarvie

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 285 KB

english, 1998

24

Oral coadministration of β-glucuronidase to increase exposure of extensively glucuronidated drugs that undergo enterohepatic recirculation

Gary Eichenbaum, C.-P. Hsu, Vangala Subrahmanyam, Jing Chen, Jan Scicinski, Robert A. Galemmo Jr., Robert W. Tuman, Dana L. Johnson

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 349 KB

english, 2012

25

Chemical libraries in drug discovery

Jan J. Scicinski

Journal:

Trends in Biotechnology

Year:

1995

Language:

english

File:

PDF, 278 KB

english, 1995

26

Application of ReactArray Robotics and Design of Experiments Techniques in Optimisation of Supported Reagent Chemistry

Jamieson, Craig, Congreve, Miles S., Emiabata-Smith, David F., Ley, Steven V., Scicinski, Jan J.

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 105 KB

english, 2002

27

Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4H-pyran-6-carboxamides

Smith, Paul W., Sollis, Steven L., Howes, Peter D., Cherry, Peter C., Starkey, Ian D., Cobley, Kevin N., Weston, Helen, Scicinski, Jan, Merritt, Andrew, Whittington, Andrew

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 203 KB

english, 1998

28

Solid-Phase Development of a 1-Hydroxybenzotriazole Linker for Heterocycle Synthesis Using Analytical Constructs

Scicinski, Jan J., Congreve, Miles S., Jamieson, Craig, Ley, Steven V., Newman, Emma S., Vinader, Victoria M., Carr, Robin A. E.

Journal:

Journal of Combinatorial Chemistry

Year:

2001

Language:

english

File:

PDF, 127 KB

english, 2001

29

Development of an Indole Safety-Catch Linker Using Analytical Constructs

Scicinski, Jan J., Congreve, Miles S., Ley, Steven V.

Journal:

Journal of Combinatorial Chemistry

Year:

2004

Language:

english

File:

PDF, 168 KB

english, 2004

30

Development and Application of a Carbonyl- 13 C-Enriched Backbone Amide Linker for Solid-Phase Reaction Monitoring

Jamieson, Craig, Congreve, Miles S., Hewitt, Peter R., Scicinski, Jan J., Ley, Steven V.

Journal:

Journal of Combinatorial Chemistry

Year:

2001

Language:

english

File:

PDF, 46 KB

english, 2001

31

Clean synthesis of α-bromo ketones and their utilisation in the synthesis of 2-alkoxy-2,3-dihydro-2-aryl-1,4-benzodioxanes, 2-amino-4-aryl-1,3-thiazoles and piperidino-2-amino-1,3-thiazoles using polymer-supported reagents

Habermann, Jörg, Ley, Steven V., Scicinski, Jan J., Scott, James S., Smits, René, Thomas, Andrew W.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1999

Language:

english

File:

PDF, 110 KB

english, 1999

32

Novel nitric oxide generating compound glycidyl nitrate enhances the therapeutic efficacy of chemotherapy and radiotherapy

Ning, Shoucheng, Bednarski, Mark, Oronsky, Bryan, Scicinski, Jan, Knox, Susan J.

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 429 KB

english, 2014

33

Meeting Announcements

Ning, Shoucheng, Bednarski, Mark, Oronsky, Bryan, Scicinski, Jan, Knox, Susan J.

Journal:

Journal of Renal Nutrition

Year:

2001

Language:

english

File:

PDF, 26 KB

english, 2001

34

Beyond Antiangiogenesis: Vascular Modulation as an Anticancer Therapy—A Review

Oronsky, Bryan T., Scicinski, Jan J., Reid, Tony, Knox, Susan

Journal:

Translational Oncology

Year:

2012

Language:

english

File:

PDF, 260 KB

english, 2012

35

The Implications of Hyponitroxia in Cancer

Oronsky, Bryan, Fanger, Gary R., Oronsky, Neil, Knox, Susan, Scicinski, Jan

Journal:

Translational Oncology

Year:

2014

Language:

english

File:

PDF, 590 KB

english, 2014

36

Development of methods for the bioanalysis of RRx-001 and metabolites

Scicinski, Jan, Oronsky, Bryan, Cooper, Vance, Taylor, Michael, Alexander, Mike, Hadar, Rebecca, Cosford, Rebecca, Fleischmann, Thomas, Fitch, William L

Journal:

Year:

2014

Language:

english

File:

PDF, 879 KB

english, 2014

37

The Scarlet Letter of Alkylation: A Mini Review of Selective Alkylating Agents

Oronsky, Bryan T., Reid, Tony, Knox, Susan J., Scicinski, Jan J.

Journal:

Translational Oncology

Year:

2012

Language:

english

File:

PDF, 131 KB

english, 2012

38

Reporter Resins for Solid-Phase Chemistry

Congreve, Miles S., Ladlow, Mark, Marshall, Peter, Parr, Nigel, Scicinski, Jan J., Sheppard, Tom, Vickerstaffe, Emma, Carr, Robin A. E.

Journal:

Organic Letters

Year:

2001

Language:

english

File:

PDF, 86 KB

english, 2001

39

The Squalestatins: Decarboxy and 4-Deoxy Analogues as Potent Squalene Synthase Inhibitors 1

Chan, Chuen, Andreotti, Daniele, Cox, Brian, Dymock, Brian W., Hutson, Julie L., Keeling, Suzanne E., McCarthy, Alun D., Procopiou, Panayiotis A., Ross, Barry C., Sareen, Meenu, Scicinski, Jan J., Sha

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 548 KB

english, 1996

40

Single Bead Characterization Using Analytical Constructs: Application to Quality Control of Libraries

Lorthioir, Olivier, Carr, Robin A. E., Congreve, Miles S., Geysen, Mario H., Kay, Corinne, Marshall, Peter, McKeown, Stephen C., Parr, Nigel J., Scicinski, Jan J., Watson, Stephen P.

Journal:

Analytical Chemistry

Year:

2001

Language:

english

File:

PDF, 108 KB

english, 2001

41

Approaches to carbocyclic analogues of the potent neuraminidase inhibitor 4-guanidino-Neu5Ac2en. X-Ray molecular structure of N-[(1S,2S,6R)-2-azido-6-benzyloxymethyl-4-formylcyclohex-3-enyl]acetamide

Chandler, Malcolm, Conroy, Richard, Cooper, Anthony W. J., Lamont, R. Brian, Scicinski, Jan J., Smart, James E., Storer, Richard, Weir, Niall G., Wilson, Richard D., Wyatt, Paul G.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1995

Language:

english

File:

PDF, 1.19 MB

english, 1995

42

Rewriting the Epigenetic Code for Tumor Resensitization: A Review

Oronsky, Bryan, Oronsky, Neil, Scicinski, Jan, Fanger, Gary, Lybeck, Michelle, Reid, Tony

Journal:

Translational Oncology

Year:

2014

Language:

english

File:

PDF, 355 KB

english, 2014

43

The War on Cancer: A Military Perspective

Oronsky, Bryan, Carter, Corey A., Mackie, Vernon, Scicinski, Jan, Oronsky, Arnold, Oronsky, Neil, Caroen, Scott, Parker, Christopher, Lybeck, Michelle, Reid, Tony

Journal:

Frontiers in Oncology

Year:

2015

Language:

english

File:

PDF, 692 KB

english, 2015

44

Impact of hemoglobin nitrite to nitric oxide reductase on blood transfusion for resuscitation from hemorrhagic shock

Cabrales, Pedro, Brouse, Chad, Ortiz, Daniel, Su, Yan, Oronsky, Bryan, Scicinski, Jan

Journal:

Asian Journal of Transfusion Science

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

45

NO to cancer: The complex and multifaceted role of nitric oxide and the epigenetic nitric oxide donor, RRx-001

Scicinski, Jan, Oronsky, Bryan, Ning, Shoucheng, Knox, Susan, Peehl, Donna, Kim, Michelle M., Langecker, Peter, Fanger, Gary

Journal:

Year:

2015

Language:

english

File:

PDF, 3.48 MB

english, 2015

46

Safety and activity of RRx-001 in patients with advanced cancer: a first-in-human, open-label, dose-escalation phase 1 study

Reid, Tony, Oronsky, Bryan, Scicinski, Jan, Scribner, Curt L, Knox, Susan J, Ning, Shoucheng, Peehl, Donna M, Korn, Ron, Stirn, Meaghan, Carter, Corey A, Oronsky, Arnold, Taylor, Michael J, Fitch, Wil

Journal:

The Lancet Oncology

Year:

2015

Language:

english

File:

PDF, 553 KB

english, 2015

47

Light-fluorous safety-catch arylgermanes ? exceptionally robust, photochemically activated precursors for biaryl synthesis by Pd(0) catalysed cross-coupling

Spivey, Alan C., Tseng, Chih-Chung, Hannah, Joseph P., Gripton, Christopher J. G., de Fraine, Paul, Parr, Nigel J., Scicinski, Jan J.

Journal:

Chemical Communications

Year:

2007

Language:

english

File:

PDF, 276 KB

english, 2007

48

Analytical Techniques for Small Molecule Solid Phase Synthesis

Scicinski, Jan, Congreve, Miles, Kay, Corinne, Ley, Steven

Journal:

Current Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 716 KB

english, 2002

49

Concurrent whole brain radiotherapy and RRx-001 for melanoma brain metastases

Kim, Michelle M., Parmar, Hemant, Cao, Yue, Knox, Susan J., Oronsky, Bryan, Scicinski, Jan, Lawrence, Theodore S., Lao, Christopher D.

Journal:

Year:

2016

Language:

english

File:

PDF, 189 KB

english, 2016

50

Partial response to carboplatin in an RRx-001 pretreated patient with EGFR-inhibitor-resistance and T790M-negative NSCLC

Carter, Corey A., Oronsky, Bryan, Caroen, Scott, Scicinski, Jan, Cabrales, Pedro, Degesys, Aiste, Brzezniak, Christina

Journal:

Respiratory Medicine Case Reports

Year:

2016

Language:

english

File:

PDF, 952 KB

english, 2016

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