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51

NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis

Di Marco, Elyse, Gray, Stephen P., Kennedy, Kit, Szyndralewiez, Cedric, Lyle, Alicia N., Lassègue, Bernard, Griendling, Kathy K., Cooper, Mark E., Schmidt, Harald H.H.W., Jandeleit-Dahm, Karin A.M.

Journal:

Free Radical Biology and Medicine

Year:

2016

Language:

english

File:

PDF, 1.68 MB

english, 2016

52

RAGE biology, atherosclerosis and diabetes

Barlovic, Drazenka Pongrac, Soro-Paavonen, Aino, Jandeleit-Dahm, Karin A. M.

Journal:

Clinical Science

Year:

2011

Language:

english

File:

PDF, 381 KB

english, 2011

53

Diabetic kidney disease

Thomas, Merlin C., Brownlee, Michael, Susztak, Katalin, Sharma, Kumar, Jandeleit-Dahm, Karin A. M., Zoungas, Sophia, Rossing, Peter, Groop, Per-Henrik, Cooper, Mark E.

Journal:

Nature Reviews Disease Primers

Year:

2015

File:

PDF, 36 KB

2015

54

Platelet Hyperreactivity in Diabetes: Focus on GPVI Signaling—Are Useful Drugs Already Available?

Arthur, Jane F., Jandeleit-Dahm, Karin, Andrews, Robert K.

Journal:

Year:

2017

Language:

english

File:

PDF, 844 KB

english, 2017

55

Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease

Gray, Stephen P., Jha, Jay C., Kennedy, Kit, van Bommel, Erik, Chew, Phyllis, Szyndralewiez, Cedric, Touyz, Rhian M., Schmidt, Harald H. H. W., Cooper, Mark E., Jandeleit-Dahm, Karin A. M.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.32 MB

english, 2017

56

Effects of Neutral Endopeptidase Inhibition in the Rat Remnant Kidney Model

Jandeleit-Dahm, Karin, Burrell, Louise M., Kanazawa, Masayuki, Casley, David, Jackson, Bruce, Johnston, Colin I.

Journal:

Kidney & Blood Pressure Research

Year:

1999

Language:

english

File:

PDF, 187 KB

english, 1999

57

The emerging role of NADPH oxidase NOX5 in vascular disease

Jha, Jay C., Watson, Anna M.D., Mathew, Geetha, de Vos, Lisanne C., Jandeleit-Dahm, Karin

Journal:

Clinical Science

Year:

2017

Language:

english

File:

PDF, 428 KB

english, 2017

58

OS 21-01 NOX1 OR NOX4 DELETION PREVENTS TYPE 1 DIABETES-INDUCED ENDOTHELIAL DYSFUNCTION

Paradis, Pierre, Ouerd, Sofiane, Idris-Khodja, Noureddine, Trindade, Michelle, Coelho, Suellen C., Jandeleit-Dahm, Karin A., Schiffrin, Ernesto L.

Journal:

Journal of Hypertension

Year:

2016

Language:

english

File:

PDF, 158 KB

english, 2016

59

PS 16-31 ENDOTHELIN-1 EXAGGERATES TYPE-1 DIABETES-ACCELERATED ATHEROSCLEROSIS THROUGH NADPH OXIDASES 1 AND 4

Paradis, Pierre, Ouerd, Sofiane, Idris-Khodja, Noureddine, Trindade, Michelle, Coelho, Suellen C., Jandeleit-Dahm, Karin A., Schiffrin, Ernesto L.

Journal:

Journal of Hypertension

Year:

2016

Language:

english

File:

PDF, 57 KB

english, 2016

60

Endothelin and Endothelin A/B Receptors Are Increased after Ischaemic Acute Renal Failure

Forbes, Josephine M., Jandeleit-Dahm, Karin, Allen, Terri J., Hewitson, Tim D., Becker, Gavin J., Jones, Colin L.

Journal:

Nephron Experimental Nephrology

Year:

2001

Language:

english

File:

PDF, 432 KB

english, 2001

61

GLP-1 receptor agonists: An example of the challenge for animal models to predict plaque instability/rupture and cardiovascular outcomes

Ying, Ya-Lan, Chen, Yung-Chih, Jandeleit-Dahm, Karin, Peter, Karlheinz

Journal:

Atherosclerosis

Year:

2017

Language:

english

File:

PDF, 176 KB

english, 2017

62

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi

Ahrens, Ingo, Chen, Yung-Chih, Topcic, Danijal, Bode, Michael, Haenel, David, Hagemeyer, Christoph E., Seeba, Hannah, Duerschmied, Daniel, Bassler, Nicole, Jandeleit-Dahm, Karin A., Sweet, Matthew J.,

Journal:

Thrombosis and Haemostasis

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

63

Metabolic Karma—The Atherogenic Legacy of Diabetes: The 2017 Edwin Bierman Award Lecture

Cooper, Mark Emmanuel, El-Osta, Assam, Allen, Terri Jean, Watson, Anna Margareta Dorothea, Thomas, Merlin Christopher, Jandeleit-Dahm, Karin Agnes Maria

Journal:

Year:

2018

Language:

english

File:

PDF, 842 KB

english, 2018

64

Cardiovascular Disease and Diabetic Kidney Disease

Maqbool, Muhammad, Cooper, Mark E., Jandeleit-Dahm, Karin A.M.

Journal:

Seminars in Nephrology

Year:

2018

Language:

english

File:

PDF, 704 KB

english, 2018

65

Local Gene Silencing of Monocyte Chemoattractant Protein-1 Prevents Vulnerable Plaque Disruption in Apolipoprotein E-Knockout Mice

Liu, Xiao Ling, Zhang, Peng Fei, Ding, Shi Fang, Wang, Yan, Zhang, Mei, Zhao, Yu Xia, Ni, Mei, Zhang, Yun, Jandeleit-Dahm, Karin

Journal:

Year:

2012

Language:

english

File:

PDF, 3.09 MB

english, 2012

66

Abnormally Low and High Ankle-Brachial Indices Are Independently Associated with Increased Left Ventricular Mass Index in Chronic Kidney Disease

Su, Ho-Ming, Lin, Tsung-Hsien, Hsu, Po-Chao, Chu, Chun-Yuan, Lee, Wen-Hsien, Chen, Szu-Chia, Lee, Chee-Siong, Voon, Wen-Chol, Lai, Wen-Ter, Sheu, Sheng-Hsiung, Jandeleit-Dahm, Karin

Journal:

Year:

2012

Language:

english

File:

PDF, 156 KB

english, 2012

67

Status of Systemic Oxidative Stresses in Patients with Primary Open-Angle Glaucoma and Pseudoexfoliation Syndrome

Tanito, Masaki, Kaidzu, Sachiko, Takai, Yasuyuki, Ohira, Akihiro, Jandeleit-Dahm, Karin

Journal:

Year:

2012

Language:

english

File:

PDF, 161 KB

english, 2012

68

Depletion of Endothelial or Smooth Muscle Cell-Specific Angiotensin II Type 1a Receptors Does Not Influence Aortic Aneurysms or Atherosclerosis in LDL Receptor Deficient Mice

Rateri, Debra L., Moorleghen, Jessica J., Knight, Victoria, Balakrishnan, Anju, Howatt, Deborah A., Cassis, Lisa A., Daugherty, Alan, Jandeleit-Dahm, Karin

Journal:

Year:

2012

Language:

english

File:

PDF, 481 KB

english, 2012

69

Activation of Sterol Regulatory Element Binding Protein and NLRP3 Inflammasome in Atherosclerotic Lesion Development in Diabetic Pigs

Li, Yu, Xu, Shanqin, Jiang, Bingbing, Cohen, Richard A., Zang, Mengwei, Jandeleit-Dahm, Karin

Journal:

Year:

2013

Language:

english

File:

PDF, 1.56 MB

english, 2013

70

Effect of Erythropoiesis-Stimulating Agents on Blood Pressure in Pre-Dialysis Patients

Suttorp, Marit M., Hoekstra, Tiny, Mittelman, Moshe, Ott, Ilka, Franssen, Casper F. M., Dekker, Friedo W., Jandeleit-Dahm, Karin

Journal:

Year:

2013

Language:

english

File:

PDF, 166 KB

english, 2013

71

HbA1C Variability and the Risk of Renal Status Progression in Diabetes Mellitus: A Meta-Analysis

Cheng, Dongsheng, Fei, Yang, Liu, Yumei, Li, Junhui, Xue, Qin, Wang, Xiaoxia, Wang, Niansong, Jandeleit-Dahm, Karin

Journal:

Year:

2014

Language:

english

File:

PDF, 369 KB

english, 2014

72

High Incidence of ACE/PAI-1 in Association to a Spectrum of Other Polymorphic Cardiovascular Genes Involving PBMCs Proinflammatory Cytokines in Hypertensive Hypercholesterolemic Patients: Reversibility with a Combination of ACE Inhibitor and Statin

AlBacha, Jeanne d’Arc, Khoury, Mira, Mouawad, Charbel, Haddad, Katia, Hamoui, Samar, Azar, Albert, Fajloun, Ziad, Makdissy, Nehman, Jandeleit-Dahm, Karin

Journal:

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

73

Coronary Atherosclerotic Plaque Detected by Computed Tomographic Angiography in Subjects with Diabetes Compared to Those without Diabetes

Khazai, Bahram, Luo, Yanting, Rosenberg, Steven, Wingrove, James, Budoff, Matthew J, Jandeleit-Dahm, Karin

Journal:

Year:

2015

Language:

english

File:

PDF, 207 KB

english, 2015

74

Anti-Hyperglycemic Agents and New-Onset Acute Myocardial Infarction in Diabetic Patients with End-Stage Renal Disease Undergoing Dialysis

Lin, Ting-Tse, Wu, Chih-Chen, Yang, Yao-Hsu, Lin, Lian-Yu, Lin, Jiunn-Lee, Chen, Pau-Chung, Hwang, Juey-Jen, Jandeleit-Dahm, Karin

Journal:

Year:

2016

Language:

english

File:

PDF, 989 KB

english, 2016

75

Murine glomerular transcriptome links endothelial cell-specific molecule-1 deficiency with susceptibility to diabetic nephropathy

Zheng, Xiaoyi, Soroush, Fariborz, Long, Jin, Hall, Evan T., Adishesha, Puneeth K., Bhattacharya, Sanchita, Kiani, Mohammad F., Bhalla, Vivek, Jandeleit-Dahm, Karin

Journal:

Year:

2017

Language:

english

File:

PDF, 9.49 MB

english, 2017

76

Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes

Spencer, Netanya Y., Yang, Zhihong, Sullivan, Jensyn Cone, Klein, Thomas, Stanton, Robert C., Jandeleit-Dahm, Karin

Journal:

Year:

2018

Language:

english

File:

PDF, 2.06 MB

english, 2018

77

Multiparametric magnetic resonance imaging of experimental chronic kidney disease: A quantitative correlation study with histology

Schley, Gunnar, Jordan, Jutta, Ellmann, Stephan, Rosen, Seymour, Eckardt, Kai-Uwe, Uder, Michael, Willam, Carsten, Bäuerle, Tobias, Jandeleit-Dahm, Karin

Journal:

Year:

2018

Language:

english

File:

PDF, 24.00 MB

english, 2018

78

A causal link between oxidative stress and inflammation in cardiovascular and renal complications of diabetes

Jha, Jay C., Ho, Florence, Dan, Christopher, Jandeleit-Dahm, Karin

Journal:

Clinical Science

Year:

2018

Language:

english

File:

PDF, 1.22 MB

english, 2018

79

A novel synthetic small molecule DMFO targets Nrf2 in modulating proinflammatory/antioxidant mediators to ameliorate inflammation

Mathew, Geetha, Sharma, Arpeeta, Pickering, Raelene J., Rosado, Carlos J., Lemarie, Jeremie, Mudgal, Jayesh, Thambi, Magith, Sebastian, Sarine, Jandeleit-Dahm, Karin A., de Haan, Judy B., Unnikrishnan

Journal:

Free Radical Research

Year:

2018

Language:

english

File:

PDF, 2.48 MB

english, 2018

80

Dipeptidyl peptidase-4 inhibitors and cardiovascular and renal disease in type 2 diabetes: What have we learned from the CARMELINA trial?

Hanssen, Nordin MJ, Jandeleit-Dahm, Karin AM

Journal:

Diabetes and Vascular Disease Research

Year:

2019

Language:

english

File:

PDF, 127 KB

english, 2019

81

Diabetes and Hypertension Differentially Affect Renal Catecholamines and Renal Reactive Oxygen Species

Watson, Anna M. D., Gould, Eleanor A. M., Penfold, Sally A., Lambert, Gavin W., Pratama, Putra Riza, Dai, Aozhi, Gray, Stephen P., Head, Geoffrey A., Jandeleit-Dahm, Karin A.

Journal:

Frontiers in Physiology

Year:

2019

Language:

english

File:

PDF, 2.66 MB

english, 2019

82

Genetic characterization of early renal changes in a novel mouse model of diabetic kidney disease

Balmer, Lois A., Whiting, Rhiannon, Rudnicka, Caroline, Gallo, Linda A., Jandeleit-Dahm, Karin A., Chow, Yan, Chow, Zenia, Richardson, Kirsty L., Forbes, Josephine M., Morahan, Grant

Journal:

Kidney International

Year:

2019

Language:

english

File:

PDF, 2.62 MB

english, 2019

83

Endothelial or vascular smooth muscle cell-specific expression of human NOX5 exacerbates renal inflammation, fibrosis and albuminuria in the Akita mouse

Jha, Jay C., Dai, Aozhi, Holterman, Chet E., Cooper, Mark E., Touyz, Rhian M., Kennedy, Chris R., Jandeleit-Dahm, Karin A. M.

Journal:

Year:

2019

File:

PDF, 2.38 MB

2019

84

Macrophage phenotype and its relationship with renal function in human diabetic nephropathy

Zhang, Xiaoliang, Yang, Ying, Zhao, Yu, Jandeleit-Dahm, Karin

Journal:

Year:

2019

File:

PDF, 3.56 MB

2019

85

The role of Nox5 in diabetic complications

Jha, Jay C., Kennedy, Chris, Dai, Aozhi, Cooper, Mark, Wastson, Anna, Touyz, Rhian, Jandeleit-Dahm, Karin

Journal:

Obesity Research & Clinical Practice

Year:

2019

Language:

english

File:

PDF, 290 KB

english, 2019

86

A physician-initiated double-blind, randomised, placebo-controlled, phase 2 study evaluating the efficacy and safety of inhibition of NADPH oxidase with the first-in-class Nox-1/4 inhibitor, GKT137831, in adults with type 1 diabetes and persistently elevated urinary albumin excretion: protocol and statistical considerations

Reutens, Anne T., Jandeleit-Dahm, Karin, Thomas, Merlin, Bach, Leon A., Colman, Peter G., Davis, Timothy M.E., D'Emden, Michael, Ekinci, Elif I., Fulcher, Greg, Hamblin, Peter Shane, Kotowicz, Mark A.

Journal:

Contemporary Clinical Trials

Year:

2019

Language:

english

File:

PDF, 491 KB

english, 2019

87

NOX inhibition: Pre-clinical and clinical studies in diabetic complications

Urner, Sofia, Ho, Florence, Jha, Jay C., Ziegler, Dan, Jandeleit-Dahm, Karin

Journal:

Antioxidants & Redox Signaling

Year:

2020

File:

PDF, 1.25 MB

2020

88

Empagliflozin modulates renal sympathetic and heart rate baroreflexes in a rabbit model of diabetes

Gueguen, Cindy, Burke, Sandra L., Barzel, Benjamin, Eikelis, Nina, Watson, Anna M. D., Jha, Jay C., Jackson, Kristy L., Sata, Yusuke, Lim, Kyungjoon, Lambert, Gavin W., Jandeleit-Dahm, Karin A. M., Co

Journal:

Year:

2020

File:

PDF, 743 KB

2020

89

Evaluating the efficacy and safety of GKT137831 in adults with type 1 diabetes and persistently elevated urinary albumin excretion: a statistical analysis plan

De Livera, Alysha M., Reutens, Anne, Cooper, Mark, Thomas, Merlin, Jandeleit-Dahm, Karin, Shaw, Jonathan E., Salim, Agus

Journal:

Year:

2020

File:

PDF, 950 KB

2020

90

Disparate Effects of Diabetes and Hyperlipidemia on Experimental Kidney Disease

Watson, Anna M. D., Gould, Eleanor A. M., Moody, Sarah C., Sivakumaran, Priyadharshini, Sourris, Karly C., Chow, Bryna S. M., KoÃ¯tka-Weber, Audrey, Allen, Terri J., Jandeleit-Dahm, Karin A. M., Coope

Journal:

Frontiers in Physiology

Year:

2020

File:

PDF, 8.11 MB

2020

91

ENDOTHELIUM-RESTRICTED ENDOTHELIN-1 OVEREXPRESSION IN TYPE-1 DIABETES WORSENS ATHEROSCLEROSIS AND IMMUNE CELL INFILTRATION VIA NOX1

Ouerd, Sofiane, Idris-Khodja, Noureddine, Trindade, Michelle, Ferreira, Nathanne S, Berillo, Olga, Coelho, Suellen C, Neves, Mario F, Jandeleit-Dahm, Karin A, Paradis, Pierre, Schiffrin, Ernesto L

Journal:

Cardiovascular Research

Year:

2020

File:

PDF, 789 KB

2020

92

Differential sympathetic response to lesion-induced chronic kidney disease in rabbits

Sata, Yusuke, Burke, Sandra L., Watson, Anna M.D., Jha, Jay C., Gueguen, Cindy, Eikelis, Nina, Lim, Kyungjoon, Jackson, Kristy L., Lambert, Gavin W., Jandeleit-Dahm, Karin A.M., Denton, Kate M., Esler

Journal:

Kidney International

Year:

2020

File:

PDF, 2.45 MB

2020

93

Biomarkers of inflammation and glomerular filtration rate in individuals with recent-onset type 1 and type 2 diabetes

Maalmi, Haifa, Herder, Christian, Strassburger, Klaus, Urner, Sofia, Jandeleit-Dahm, Karin, Zaharia, Oana-Patricia, Karusheva, Yanislava, Bongaerts, Brenda Wilhelma Corinna, Rathmann, Wolfgang, Burkar

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2020

File:

PDF, 1.11 MB

2020

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