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51

Exploration of inhibitors for diaminopimelate aminotransferase

Chenguang Fan, Matthew D. Clay, Michael K. Deyholos, John C. Vederas

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.57 MB

english, 2010

52

Structural variations in keto-glutamines for improved inhibition against hepatitis A virus 3C proteinase

Rajendra P Jain, John C Vederas

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 284 KB

english, 2004

53

Spermicidal bacteriocins: Lacticin 3147 and subtilosin A

Lara Silkin, Shereen Hamza, Susan Kaufman, Steven L. Cobb, John C. Vederas

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 147 KB

english, 2008

54

Fracturing Rings to Understand Lantibiotics

Sabesan Yoganathan, John C. Vederas

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 211 KB

english, 2008

55

Membrane permeabilization, orientation, and antimicrobial mechanism of subtilosin A

Sathiah Thennarasu, Dong-Kuk Lee, Alan Poon, Karen E. Kawulka, John C. Vederas, Ayyalusamy Ramamoorthy

Journal:

Chemistry and Physics of Lipids

Year:

2005

Language:

english

File:

PDF, 390 KB

english, 2005

56

A convenient preparation of thioether functionalized porphyrins

Michael M. Pollard, John C. Vederas

Journal:

Year:

2006

Language:

english

File:

PDF, 631 KB

english, 2006

57

Application of stable isotope labelling methodology to the biosynthesis of the mycotoxin, terretonin, by aspergillus terreus: incorporation of 13C-labelled acetates and methionine, 2H- and 13C, 18O-labelled ethyl 3,5-dimethylorsellinate and oxygen-18 gas

C.Rupert McIntyre, Fiona E. Scott, Thomas J. Simpson, Laird A. Trimble, John C. Vederas

Journal:

Year:

1989

Language:

english

File:

PDF, 965 KB

english, 1989

58

Synthesis of tripeptide inhibitors of peptidylglycine α-amidating monooxygenase (PAM) containing D- and L-styrylglycine

Mark D. Andrews, Kelly A. O'Callaghan, John C. Vederas

Journal:

Year:

1997

Language:

english

File:

PDF, 745 KB

english, 1997

59

Biosynthetic incorporation of advanced precursors into dehydrocurvularin, a polyketide phytotoxin from Alternaria cinerariae

Yaoquan Liu, Zhe Li, John C. Vederas

Journal:

Year:

1998

Language:

english

File:

PDF, 1.25 MB

english, 1998

60

Reaction of trimethylsilylamines with N-Cbz-L-serine-β-lactone: A convenient route to optically pure β-amino-L-alanine derivatives

Elaref S. Ratemi, John C. Vederas

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 305 KB

english, 1994

61

Amination with N-benzyloxycarbonyl-3-phenyloxaziridine as a route to sensitive chiral α-hydrazino acids: Synthesis of l-hydrazino serine

Daniel A. Niederer, James T. Kapron, John C. Vederas

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 307 KB

english, 1993

62

Conversion of cyclic nonaketides to lovastatin and compactin by a lovc deficient mutant of Aspergillus terreus

Karine Auclair, Jonathan Kennedy, C.Richard Hutchinson, John C Vederas

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 274 KB

english, 2001

63

Bacterial diaminopimelate metabolism as a target for antibiotic design

Russell J. Cox, Andrew Sutherland, John C. Vederas *

Journal:

Bioorganic & Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 1.70 MB

english, 2000

64

Synthesis and testing of azaglutamine derivatives as inhibitors of Hepatitis A Virus (HAV) 3C proteinase

Yanting Huang, Bruce A Malcolm, John C Vederas

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 293 KB

english, 1999

65

Rapid mass spectrometric determination of preferred irreversible proteinase inhibitors in combinatorial libraries

John E. Mckendrick, Sven Frormann, Colin Luo, Paul Semchuck, John C. Vederas, Bruce A. Malcolm

Journal:

International Journal of Mass Spectrometry

Year:

1998

Language:

english

File:

PDF, 1005 KB

english, 1998

66

Protein farnesyltransferase inhibitors interfere with farnesyl diphosphate binding by rubber transferase

Christopher J. D. Mau, Sylvie Garneau, Andrew A. Scholte, Jennifer E. Van Fleet, John C. Vederas, Katrina Cornish

Journal:

Year:

2003

Language:

english

File:

PDF, 304 KB

english, 2003

67

Production of piscicolin 126 byCarnobacterium maltaromaticumUAL26 is controlled by temperature and induction peptide concentration

Lucas J. Gursky, Nathaniel I. Martin, Darren J. Derksen, Marco J. van Belkum, Kamaljit Kaur, John C. Vederas, Michael E. Stiles, Lynn M. McMullen

Journal:

Archives of Microbiology

Year:

2006

Language:

english

File:

PDF, 417 KB

english, 2006

68

Cloning and Characterization of the Gene Cluster Involved in the Production of the Circular Bacteriocin Carnocyclin A

Marco J. van Belkum, Leah A. Martin-Visscher, John C. Vederas

Journal:

Probiotics and Antimicrobial Proteins

Year:

2010

Language:

english

File:

PDF, 291 KB

english, 2010

69

Identification and comparison of natural rubber from two Lactuca species

Bradley S. Bushman, Andrew A. Scholte, Katrina Cornish, Deborah J. Scott, Jenny L. Brichta, John C. Vederas, Oswaldo Ochoa, Richard W. Michelmore, David K. Shintani, Steven J. Knapp

Journal:

Year:

2006

Language:

english

File:

PDF, 209 KB

english, 2006

70

In vitro and ex vivo inhibition of hepatitis A virus 3C proteinase by a peptidyl monofluoromethyl ketone

Tina S Morris, Sven Frormann, Shirley Shechosky, Christopher Lowe, Manjinder S Lall, Verena Gauss-Müller, Robert H Purcell, Suzanne U Emerson, John C Vederas, Bruce A Malcolm

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 1.14 MB

english, 1997

71

NMR solution structure of the precursor for carnobacteriocin B2, an antimicrobial peptide from Carnobacterium piscicola : Implications of the α-helical leader section for export and inhibition of type IIa bacteriocin activity

Tara Sprules, Karen E. Kawulka, Alan C. Gibbs, David S. Wishart, John C. Vederas

Journal:

Year:

2004

Language:

english

File:

PDF, 297 KB

english, 2004

72

The activity of bacteriocins from Carnobacterium maltaromaticum UAL307 against Gram-negative bacteria in combination with EDTA treatment

Leah A. Martin-Visscher, Sabesan Yoganathan, Clarissa S. Sit, Christopher T. Lohans, John C. Vederas

Journal:

FEMS Microbiology Letters

Year:

2011

Language:

english

File:

PDF, 264 KB

english, 2011

73

Fundamental functionality: recent developments in understanding the structure–activity relationships of lantibiotic peptides

Ross, Avena C, Vederas, John C

Journal:

The Journal of Antibiotics

Year:

2010

Language:

english

File:

PDF, 578 KB

english, 2010

74

Aspects of the biosynthesis of non-aromatic fungal polyketides by iterative polyketide synthases

C. Richard Hutchinson, Jonathan Kennedy, Cheonseok Park, Steven Kendrew, Karine Auclair, John Vederas

Journal:

Antonie van Leeuwenhoek

Year:

2000

Language:

english

File:

PDF, 169 KB

english, 2000

75

Synthesis of optically pure .alpha.-amino acids via salts of .alpha.-amino-.beta.-propiolactone

Arnold, Lee D., May, Robert G., Vederas, John Christopher.

Journal:

Journal of the American Chemical Society

Year:

1988

Language:

english

File:

PDF, 742 KB

english, 1988

76

NMR method to detect stereospecific deuterium labeling at diastereotopic methylene hydrogens: selective proton, carbon-13 heteronuclear shift correlation

Trimble, Laird A., Reese, Paul B., Vederas, John C.

Journal:

Journal of the American Chemical Society

Year:

1985

Language:

english

File:

PDF, 408 KB

english, 1985

77

For the record: The three-dimensional structure of the ternary complex of Corynebacterium glutamicum diaminopimelate dehydrogenase-NADPH-L-2-amino-6-methylene-pimelate

Maurizio Cirilli, Giovanna Scapin, Andrew Sutherland, John C. Vederas, John S. Blanchard

Journal:

Protein Science

Year:

2000

Language:

english

File:

PDF, 1.56 MB

english, 2000

78

[Topics in Current Chemistry] Biosynthesis Volume 195 || Biosynthesis of Vitamin B12

Leeper, Finian J., Vederas, John C.

Year:

1998

Language:

english

File:

PDF, 801 KB

english, 1998

79

Synthesis and structure–activity relationships of o-sulfonamido-arylhydrazides as inhibitors of ll-diaminopimelate aminotransferase (ll-DAP-AT)

Fan, Chenguang, Vederas, John C.

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 540 KB

english, 2012

80

The Synthesis of Active and Stable Diaminopimelate Analogues of the Lantibiotic Peptide Lactocin S

Ross, Avena C., McKinnie, Shaun M. K., Vederas, John C.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 347 KB

english, 2012

81

Biosynthesis of Aminovinyl-Cysteine-Containing Peptides and Its Application in the Production of Potential Drug Candidates

Sit, Clarissa S., Yoganathan, Sabesan, Vederas, John C.

Journal:

Accounts of Chemical Research

Year:

2011

Language:

english

File:

PDF, 928 KB

english, 2011

82

The stereoselective synthesis of aziridine analogues of diaminopimelic acid (DAP) and their interaction with dap epimerase

Diaper, Christopher M., Sutherland, Andrew, Pillai, Bindu, James, Michael N. G., Semchuk, Paul, Blanchard, John S., Vederas, John C.

Journal:

Organic & Biomolecular Chemistry

Year:

2005

Language:

english

File:

PDF, 317 KB

english, 2005

83

Unsaturated α-aminopimelic acids as potent inhibitors of meso-diaminopimelic acid (DAP) D-dehydrogenase

Sutherland, Andrew, Caplan, Jennifer F., Vederas, John C.

Journal:

Chemical Communications

Year:

1999

Language:

english

File:

PDF, 130 KB

english, 1999

84

Conjugate addition of radicals generated from diacyloxyiodobenzenes to dehydroamino acid derivatives; a synthesis of diaminopimelic acid analogues

Sutherland, Andrew, Vederas, John C.

Journal:

Chemical Communications

Year:

2002

Language:

english

File:

PDF, 128 KB

english, 2002

85

Crystal Structure of an Inhibitor Complex of the 3C Proteinase from Hepatitis A Virus (HAV) and Implications for the Polyprotein Processing in HAV

Ernst M. Bergmann, Maia M. Cherney, John Mckendrick, Sven Frormann, Colin Luo, Bruce A. Malcolm, John C. Vederas, Michael N.G. James

Journal:

Year:

1999

Language:

english

File:

PDF, 673 KB

english, 1999

86

Paenibacillus polymyxa PKB1 Produces Variants of Polymyxin B-Type Antibiotics

Mohamed Shaheen, Jingru Li, Avena C. Ross, John C. Vederas, Susan E. Jensen

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 754 KB

english, 2011

87

Enzymatic synthesis of valerena-4,7(11)-diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis)

Bryan W. Pyle, Hue T. Tran, Benjamin Pickel, Tegan M. Haslam, Zhizeng Gao, Gillian MacNevin, John C. Vederas, Soo-Un Kim, Dae-Kyun Ro

Journal:

Year:

2012

Language:

english

File:

PDF, 307 KB

english, 2012

88

Amination of chiral enolates by dialkyl azodiformates. Synthesis of .alpha.-hydrazino acids and .alpha.-amino acids

Trimble, Laird A., Vederas, John C.

Journal:

Journal of the American Chemical Society

Year:

1986

Language:

english

File:

PDF, 422 KB

english, 1986

89

Synthesis and acylation of salts of L-threonine .beta.-lactone: a route to .beta.-lactone antibiotics

Pu, Yunlong, Martin, Fionna M., Vederas, John C.

Journal:

Journal of Organic Chemistry

Year:

1991

Language:

english

File:

PDF, 524 KB

english, 1991

90

The Enzymatic Formation of Novel Bile Acid Primary Amides

Lawrence King III, Stephen Barnes, Uta Glufke, Matthias E. Henz, Marion Kirk, Kathleen A. Merkler, John C. Vederas, Benjamin J. Wilcox, David J. Merkler

Journal:

Archives of Biochemistry and Biophysics

Year:

2000

Language:

english

File:

PDF, 140 KB

english, 2000

91

Amidation of Salicyluric Acid and Gentisuric Acid: A Possible Role for Peptidylglycine α-Amidating Monooxygenase in the Metabolism of Aspirin

Jodi L. DeBlassio, Mitchell A. deLong, Uta Glufke, Raviraj Kulathila, Kathleen A. Merkler, John C. Vederas, David J. Merkler

Journal:

Archives of Biochemistry and Biophysics

Year:

2000

Language:

english

File:

PDF, 125 KB

english, 2000

92

An acid metabolite of cyclosporine

Neil R. Hartman, Laird A. Trimble, John C. Vederas, Ian Jardine

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 406 KB

english, 1985

93

Effect of analogues of diaminopimelic acid on the meso-diaminopimelate-adding enzyme from Escherichia coli

Geneviève Auger, Jean van Heijenoort, John C. Vederas, Didier Blanot

Journal:

Year:

1996

Language:

english

File:

PDF, 398 KB

english, 1996

94

The circular bacteriocin, carnocyclin A, forms anion-selective channels in lipid bilayers

Xiandi Gong, Leah A. Martin-Visscher, Drew Nahirney, John C. Vederas, Marek Duszyk

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2009

Language:

english

File:

PDF, 750 KB

english, 2009

95

Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase

Bindu Pillai, Maia Cherney, Christopher M. Diaper, Andrew Sutherland, John S. Blanchard, John C. Vederas, Michael N.G. James

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 1.37 MB

english, 2007

96

Functional characterization of recombinant hyoscyamine 6β-hydroxylase from Atropa belladonna

Jing Li, Marco J. van Belkum, John C. Vederas

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 693 KB

english, 2012

97

Dual Modes of Modification of Hepatitis A Virus 3C Protease by a Serine-derived β-Lactone: Selective Crystallization and Formation of a Functional Catalytic Triad in the Active Site

Jiang Yin, Ernst M. Bergmann, Maia M. Cherney, Manjinder S. Lall, Rajendra P. Jain, John C. Vederas, Michael N.G. James

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 1.22 MB

english, 2005

98

An Episulfide Cation (Thiiranium Ring) Trapped in the Active Site of HAV 3C Proteinase Inactivated by Peptide-based Ketone Inhibitors

Jiang Yin, Maia M. Cherney, Ernst M. Bergmann, Jianmin Zhang, Carly Huitema, Hanna Pettersson, Lindsay D. Eltis, John C. Vederas, Michael N.G. James

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 1.01 MB

english, 2006

99

Crystal Structure of ll-Diaminopimelate Aminotransferase from Arabidopsis thaliana: A Recently Discovered Enzyme in the Biosynthesis of l-Lysine by Plants and Chlamydia

Nobuhiko Watanabe, Maia M. Cherney, Marco J. van Belkum, Sandra L. Marcus, Mitchel D. Flegel, Matthew D. Clay, Michael K. Deyholos, John C. Vederas, Michael N.G. James

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 3.74 MB

english, 2007

100

A Mechanistic View of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-like Peptidase

Jiang Yin, Chunying Niu, Maia M. Cherney, Jianmin Zhang, Carly Huitema, Lindsay D. Eltis, John C. Vederas, Michael N.G. James

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 2.61 MB

english, 2007