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51

Synthesis and Reactivity of the Catechol Metabolites from the Equine Estrogen, 8,9-Dehydroestrone

Zhang, Fagen, Yao, Dan, Hua, Yousheng, van Breemen, Richard B., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2001

Language:

english

File:

PDF, 129 KB

english, 2001

52

Theoretical studies of imidazole nitrenium and carbenium ions

Judy L. Bolton, Robert A. McClelland

Journal:

Journal of Molecular Structure: THEOCHEM

Year:

1988

Language:

english

File:

PDF, 613 KB

english, 1988

53

Altered apoptotic response in MCF 10A cells treated with the equine estrogen metabolite, 4-hydroxyequilenin

Yan Li, Jiaqin Yao, Minsun Chang, Muriel Cuendet, Judy L. Bolton

Journal:

Toxicology Letters

Year:

2004

Language:

english

File:

PDF, 123 KB

english, 2004

54

Bioactivation of Selective Estrogen Receptor Modulators (SERMs)

Dowers, Tamara S., Qin, Zhi-Hui, Thatcher, Gregory R. J., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2006

Language:

english

File:

PDF, 421 KB

english, 2006

55

Benzothiophene Selective Estrogen Receptor Modulators with Modulated Oxidative Activity and Receptor Affinity

Qin, Zhihui, Kastrati, Irida, Chandrasena, R. Esala P., Liu, Hong, Yao, Ping, Petukhov, Pavel A., Bolton, Judy L., Thatcher, Gregory R. J.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 341 KB

english, 2007

56

Analysis of Protein Covalent Modification by Xenobiotics Using a Covert Oxidatively Activated Tag: Raloxifene Proof-of-Principle Study

Liu, Ju, Li, Qian, Yang, Xiaofeng, van Breemen, Richard B., Bolton, Judy L., Thatcher, Gregory R. J.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 431 KB

english, 2005

57

Uterine Peroxidase-Catalyzed Formation of Diquinone Methides from the Selective Estrogen Receptor Modulators Raloxifene and Desmethylated Arzoxifene

Liu, Hong, Qin, Zhihui, Thatcher, Gregory R. J., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 272 KB

english, 2007

58

Bioactivation of the Selective Estrogen Receptor Modulator Acolbifene to Quinone Methides

Liu, Ju, Liu, Hong, van Breemen, Richard B., Thatcher, Gregory R. J., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 224 KB

english, 2005

59

4-Hydroxylated Metabolites of the Antiestrogens Tamoxifen and Toremifene Are Metabolized to Unusually Stable Quinone Methides

Fan, Peter W., Zhang, Fagen, Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2000

Language:

english

File:

PDF, 210 KB

english, 2000

60

Xanthohumol Isolated from Humulus lupulus Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase

Dietz, Birgit M., Kang, Young-Hwa, Liu, Guowen, Eggler, Aimee L., Yao, Ping, Chadwick, Lucas R., Pauli, Guido F., Farnsworth, Norman R., Mesecar, Andrew D., van Breemen, Richard B., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 310 KB

english, 2005

61

Estrogens and Congeners from Spent Hops ( Humulus l upulus )

Chadwick, Lucas R., Nikolic, Dejan, Burdette, Joanna E., Overk, Cassia R., Bolton, Judy L., van Breemen, Richard B., Fröhlich, Roland, Fong, Harry H. S., Farnsworth, Norman R., Pauli, Guido F.

Journal:

Journal of Natural Products

Year:

2004

Language:

english

File:

PDF, 203 KB

english, 2004

62

The enzymic formation and chemical reactivity of quinone methides correlate with alkylphenol-induced toxicity in rat hepatocytes

Bolton, Judy L., Valerio, Luis G., Thompson, John A.

Journal:

Chemical Research in Toxicology

Year:

1992

Language:

english

File:

PDF, 862 KB

english, 1992

63

Kinetics and mechanism of the decomposition in aqueous solutions of 2-(hydroxyamino)imidazoles

Bolton, Judy L., McClelland, Robert A.

Journal:

Journal of the American Chemical Society

Year:

1989

Language:

english

File:

PDF, 1.21 MB

english, 1989

64

Chemical Modification Modulates Estrogenic Activity, Oxidative Reactivity, and Metabolic Stability in 4‘F-DMA, a New Benzothiophene Selective Estrogen Receptor Modulator

Liu, Hong, Bolton, Judy L., Thatcher, Gregory R. J.

Journal:

Chemical Research in Toxicology

Year:

2006

Language:

english

File:

PDF, 149 KB

english, 2006

65

Evidence That 4-Allyl-o-quinones Spontaneously Rearrange to Their More Electrophilic Quinone Methides: Potential Bioactivation Mechanism for the Hepatocarcinogen Safrole

Bolton, Judy L., Acay, Nick M., Vukomanovic, Vesna

Journal:

Chemical Research in Toxicology

Year:

1994

Language:

english

File:

PDF, 1.43 MB

english, 1994

66

The Influence of the p-Alkyl Substituent on the Isomerization of o-Quinones to p-Quinone Methides: Potential Bioactivation Mechanism for Catechols

Iverson, Suzanne L., Hu, Li Qing, Vukomanovic, Vesna, Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

1995

Language:

english

File:

PDF, 1.39 MB

english, 1995

67

Alkylation of 2‘-Deoxynucleosides and DNA by Quinone Methides Derived from 2,6-Di- tert -butyl-4-methylphenol

Lewis, Mark A., Graff Yoerg, Darla, Bolton, Judy L., Thompson, John A.

Journal:

Chemical Research in Toxicology

Year:

1996

Language:

english

File:

PDF, 233 KB

english, 1996

68

Obituary for Professor Allan H. Conney (1930–2013)

Guengerich, F. Peter, Bolton, Judy L., Lu, Anthony Y. H.

Journal:

Chemical Research in Toxicology

Year:

2013

Language:

english

File:

PDF, 677 KB

english, 2013

69

Modulation of estrogen chemical carcinogenesis by botanical supplements used for postmenopausal women's health

Snelten, Courtney S., Dietz, Birgit, Bolton, Judy L.

Journal:

Drug Discovery Today: Disease Mechanisms

Year:

2012

Language:

english

File:

PDF, 289 KB

english, 2012

70

Seasonal Variation of Red Clover ( Trifolium pratense L., Fabaceae) Isoflavones and Estrogenic Activity

Booth, Nancy L., Overk, Cassia R., Yao, Ping, Totura, Steve, Deng, Yunfan, Hedayat, A. S., Bolton, Judy L., Pauli, Guido F., Farnsworth, Norman R.

Journal:

Journal of Agricultural and Food Chemistry

Year:

2006

Language:

english

File:

PDF, 315 KB

english, 2006

71

Diary of the Week

Kearse, Wilfred S., Sago, Alvin L., Peretsman, Samuel J., Bolton, Judy O., Holcomb, Richard G., Reddy, Pratap K., Bernhard, Peter H., Eppel, Stephen M., Lewis, Jean H., Gladshteyn, Mark, Melman, Arnol

Journal:

Year:

1960

Language:

english

File:

PDF, 335 KB

english, 1960

72

An evaluation of trauma focused cognitive behavioral therapy for children in Zambia

Murray, Laura K., Familiar, Itziar, Skavenski, Stephanie, Jere, Elizabeth, Cohen, Judy, Imasiku, Mwiya, Mayeya, John, Bass, Judith K., Bolton, Paul

Journal:

Child Abuse & Neglect

Year:

2013

Language:

english

File:

PDF, 437 KB

english, 2013

73

C-Reactive Protein and Colorectal Adenoma in the Clue II Cohort

Konstantinos K. Tsilidis, Thomas P. Erlinger, Nader Rifai, Sandy Hoffman, Judy Hoffman-Bolton, Kathy J. Helzlsouer and Elizabeth A. Platz

Journal:

Cancer Causes & Control

Year:

2008

Language:

english

File:

PDF, 1.82 MB

english, 2008

74

Synthesis and Reactivity of a Potential Carcinogenic Metabolite of Tamoxifen: 3,4-Dihydroxytamoxifen- o -quinone

Zhang, Fagen, Fan, Peter W., Liu, Xuemei, Shen, Lixin, van Breemen, Richard B., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2000

Language:

english

File:

PDF, 188 KB

english, 2000

75

A Metabolite of Equine Estrogens, 4-Hydroxyequilenin, Induces DNA Damage and Apoptosis in Breast Cancer Cell Lines

Chen, Yumei, Liu, Xuemei, Pisha, Emily, Constantinou, Andreas I., Hua, Yousheng, Shen, Lixin, van Breemen, Richard B., Elguindi, Ebrahim C., Blond, Sylvie Y., Zhang, Fagen, Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2000

Language:

english

File:

PDF, 229 KB

english, 2000

76

Formation and reactivity of alternative quinone methides from butylated hydroxytoluene: possible explanation for species-specific pneumotoxicity

Bolton, Judy L., Sevestre, Hubert, Ibe, Basil O., Thompson, John A.

Journal:

Chemical Research in Toxicology

Year:

1990

Language:

english

File:

PDF, 696 KB

english, 1990

77

Equine Estrogen Metabolite 4-Hydroxyequilenin Induces DNA Damage in the Rat Mammary Tissues: Formation of Single-Strand Breaks, Apurinic Sites, Stable Adducts, and Oxidized Bases

Zhang, Fagen, Swanson, Steven M., van Breemen, Richard B., Liu, Xuemei, Yang, Yanan, Gu, Chungang, Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2001

Language:

english

File:

PDF, 72 KB

english, 2001

78

In Vitro Serotonergic Activity of Black Cohosh and Identification of N ω -Methylserotonin as a Potential Active Constituent

Powell, Sharla L., Gödecke, Tanja, Nikolic, Dejan, Chen, Shao-Nong, Ahn, Soyoun, Dietz, Birgit, Farnsworth, Norman R., van Breemen, Richard B., Lankin, David C., Pauli, Guido F., Bolton, Judy L.

Journal:

Journal of Agricultural and Food Chemistry

Year:

2008

Language:

english

File:

PDF, 414 KB

english, 2008

79

Problematic Detoxification of Estrogen Quinones by NAD(P)H-Dependent Quinone Oxidoreductase and Glutathione- S- transferase

Chandrasena, R. Esala P., Edirisinghe, Praneeth D., Bolton, Judy L., Thatcher, Gregory R. J.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 240 KB

english, 2008

80

Oxo Substituents Markedly Alter the Phase II Metabolism of α-Hydroxybutenylbenzenes: Models Probing the Bioactivation Mechanisms of Tamoxifen

Ramakrishna, Kornepati V., Fan, Peter W., Boyer, C. Scott, Dalvie, Deepak, Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 291 KB

english, 1997

81

Potential Mechanisms of Estrogen Quinone Carcinogenesis

Bolton, Judy L., Thatcher, Gregory R. J.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 432 KB

english, 2008

82

Lifetime and Reactivity of an Ultimate Tamoxifen Carcinogen: The Tamoxifen Carbocation

Sanchez, Cristina, Shibutani, Shinya, Dasaradhi, Lakkaraju, Bolton, Judy L., Fan, Peter W., McClelland, Robert A.

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 61 KB

english, 1998

83

Reaction of the Premarin Metabolite 4-Hydroxyequilenin Semiquinone Radical with 2‘-Deoxyguanosine: Formation of Unusual Cyclic Adducts

Shen, Li, Qiu, Shengxiang, van Breemen, Richard B., Zhang, Fagen, Chen, Yumei, Bolton, Judy L.

Journal:

Journal of the American Chemical Society

Year:

1997

Language:

english

File:

PDF, 70 KB

english, 1997

84

Mechanism of Isomerization of 4-Propyl- o -quinone to Its Tautomeric p -Quinone Methide

Bolton, Judy L., Wu, Hao Ming, Hu, Li Qing

Journal:

Chemical Research in Toxicology

Year:

1996

Language:

english

File:

PDF, 278 KB

english, 1996

85

Botanical Dietary Supplements Gone Bad

Dietz, Birgit, Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 74 KB

english, 2007

86

Heterolytic versus homolytic peroxide bond cleavage by sperm whale myoglobin and myoglobin mutants

Allentoff, Alban J., Bolton, Judy L., Wilks, Angela, Thompson, John A., Ortiz de Montellano, Paul R.

Journal:

Journal of the American Chemical Society

Year:

1992

Language:

english

File:

PDF, 774 KB

english, 1992

87

Role of Quinoids in Estrogen Carcinogenesis

Bolton, Judy L., Pisha, Emily, Zhang, Fagen, Qiu, Shengxiang

Journal:

Chemical Research in Toxicology

Year:

1998

Language:

english

File:

PDF, 394 KB

english, 1998

88

Specificity of Human Aldo-Keto Reductases, NAD(P)H:Quinone Oxidoreductase, and Carbonyl Reductases to Redox-Cycle Polycyclic Aromatic Hydrocarbon Diones and 4-Hydroxyequilenin- o- quinone

Shultz, Carol A., Quinn, Amy M., Park, Jong-Heum, Harvey, Ronald G., Bolton, Judy L., Maser, Edmund, Penning, Trevor M.

Journal:

Chemical Research in Toxicology

Year:

2011

Language:

english

File:

PDF, 4.12 MB

english, 2011

89

Obituary for Professor Garold S. Yost (1948–2014)

Bolton, Judy L., Reilly, Christopher A., Franklin, Michael R.

Journal:

Chemical Research in Toxicology

Year:

2014

Language:

english

File:

PDF, 677 KB

english, 2014

90

Bioactivation of the Selective Estrogen Receptor Modulator Desmethylated Arzoxifene to Quinoids: 4‘-Fluoro Substitution Prevents Quinoid Formation

Liu, Hong, Liu, Ju, van Breemen, Richard B., Thatcher, Gregory R. J., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 213 KB

english, 2005

91

Inhibition of Cellular Enzymes by Equine Catechol Estrogens in Human Breast Cancer Cells: Specificity for Glutathione S -Transferase P1-1

Yao, Jiaqin, Chang, Minsun, Li, Yan, Pisha, Emily, Liu, Xuemei, Yao, Dan, Elguindi, Ebrahim C., Blond, Sylvie Y., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2002

Language:

english

File:

PDF, 89 KB

english, 2002

92

Inhibition of Glutathione S -Transferase Activity by the Quinoid Metabolites of Equine Estrogens

Chang, Minsun, Zhang, Fagen, Shen, Li, Pauss, Nikkole, Alam, Iram, van Breemen, Richard B., Blond, Sylvie Y., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

1998

Language:

english

File:

PDF, 196 KB

english, 1998

93

The Equine Estrogen Metabolite 4-Hydroxyequilenin Causes DNA Single-Strand Breaks and Oxidation of DNA Bases in Vitro

Chen, Yumei, Shen, Li, Zhang, Fagen, Lau, Serrine S., van Breemen, Richard B., Nikolic, Dejan, Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

1998

Language:

english

File:

PDF, 117 KB

english, 1998

94

Unexpected Hormonal Activity of a Catechol Equine Estrogen Metabolite Reveals Reversible Glutathione Conjugation

Peng, Kuan-Wei, Chang, Minsun, Wang, Yue-Ting, Wang, Zhican, Qin, Zhihui, Bolton, Judy L., Thatcher, Gregory R. J.

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 1.41 MB

english, 2010

95

Synthesis and Reactivity of Potential Toxic Metabolites of Tamoxifen Analogues: Droloxifene and Toremifene o -Quinones

Yao, Dan, Zhang, Fagen, Yu, Linning, Yang, Yanan, van Breemen, Richard B., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2001

Language:

english

File:

PDF, 132 KB

english, 2001

96

Screening Botanical Extracts for Quinoid Metabolites

Johnson, Benjamin M., Bolton, Judy L., van Breemen, Richard B.

Journal:

Chemical Research in Toxicology

Year:

2001

Language:

english

File:

PDF, 82 KB

english, 2001

97

Oxidative DNA Damage Induced by Equine Estrogen Metabolites: Role of Estrogen Receptor α

Liu, Xuemei, Yao, Jiaqin, Pisha, Emily, Yang, Yanan, Hua, Yousheng, van Breemen, Richard B., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2002

Language:

english

File:

PDF, 92 KB

english, 2002

98

Catechol Estrogen 4-Hydroxyequilenin Is a Substrate and an Inhibitor of Catechol- O -Methyltransferase

Yao, Jiaqin, Li, Yan, Chang, Minsun, Wu, Huaping, Yang, Xiaofeng, Goodman, Julie E., Liu, Xuemei, Liu, Hong, Mesecar, Andrew D., van Breemen, Richard B., Yager, James D., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 132 KB

english, 2003

99

Development of a Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry Method for Analysis of Stable 4-Hydroxyequilenin−DNA Adducts in Human Breast Cancer Cells

Wang, Zhican, Edirisinghe, Praneeth, Sohn, Johann, Qin, Zhihui, Geacintov, Nicholas E., Thatcher, Gregory R. J., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2009

Language:

english

File:

PDF, 785 KB

english, 2009

100

Alkylation of 2‘-Deoxynucleosides and DNA by the Premarin Metabolite 4-Hydroxyequilenin Semiquinone Radical

Shen, Li, Qiu, Shengxiang, Chen, Yumei, Zhang, Fagen, van Breemen, Richard B., Nikolic, Dejan, Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

1998

Language:

english

File:

PDF, 189 KB

english, 1998