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1

Questionnaire based assessment of risk factors for primary biliary cirrhosis

Lammert, Craig, Nguyen, Douglas L., Juran, Brian D., Schlicht, Erik, Larson, Joseph J., Atkinson, Elizabeth J., Lazaridis, Konstantinos N.

Journal:

Digestive and Liver Disease

Year:

2013

Language:

english

File:

PDF, 272 KB

english, 2013

2

Studying the Exposome to Understand the Environmental Determinants of Complex Liver Diseases

Cheung, Angela C., Walker, Douglas I., Juran, Brian D., Miller, Gary W., Lazaridis, Konstantinos N.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.64 MB

english, 2019

3

Is the FXR the fix for cholesterol gallstone disease?

Brian D. Juran, Konstantinos N. Lazaridis

Journal:

Year:

2005

Language:

english

File:

PDF, 384 KB

english, 2005

4

Genomics and complex liver disease: Challenges and opportunities

Brian D. Juran, Konstantinos N. Lazaridis

Journal:

Year:

2006

Language:

english

File:

PDF, 607 KB

english, 2006

5

Increased prevalence of antimitochondrial antibodies in first-degree relatives of patients with primary biliary cirrhosis

Konstantinos N. Lazaridis, Brian D. Juran, Gwen M. Boe, Joshua P. Slusser, Mariza de Andrade, Henry A. Homburger, Karthik Ghosh, E. Rolland Dickson, Keith D. Lindor, Gloria M. Petersen

Journal:

Year:

2007

Language:

english

File:

PDF, 187 KB

english, 2007

6

Interacting alleles of the coinhibitory immunoreceptor genes cytotoxic T-lymphocyte antigen 4 and programmed cell-death 1 influence risk and features of primary biliary cirrhosis

Brian D. Juran, Elizabeth J. Atkinson, Erik M. Schlicht, Brooke L. Fridley, Gloria M. Petersen, Konstantinos N. Lazaridis

Journal:

Year:

2008

Language:

english

File:

PDF, 125 KB

english, 2008

7

Carriage of a tumor necrosis factor polymorphism amplifies the cytotoxic T-lymphocyte antigen 4 attributed risk of primary biliary cirrhosis: Evidence for a gene–gene interaction

Brian D. Juran, Elizabeth J. Atkinson, Joseph J. Larson, Erik M. Schlicht, Xiangdong Liu, E. Jenny Heathcote, Gideon M. Hirschfield, Katherine A. Siminovitch, Konstantinos N. Lazaridis

Journal:

Year:

2010

Language:

english

File:

PDF, 180 KB

english, 2010

8

Primary biliary cirrhosis

Douglas L. Nguyen, Brian D. Juran, Konstantinos N. Lazaridis

Journal:

Best Practice & Research Clinical Gastroenterology

Year:

2010

Language:

english

File:

PDF, 132 KB

english, 2010

9

Genetic polymorphisms of matrix metalloproteinase 3 in primary sclerosing cholangitis

Brian D. Juran, Elizabeth J. Atkinson, Erik M. Schlicht, Joseph J. Larson, David Ellinghaus, Andre Franke, Konstantinos N. Lazaridis

Journal:

Liver International

Year:

2011

Language:

english

File:

PDF, 196 KB

english, 2011

10

Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis

Hirschfield, Gideon M, Liu, Xiangdong, Han, Younghun, Gorlov, Ivan P, Lu, Yan, Xu, Chun, Lu, Yue, Chen, Wei, Juran, Brian D, Coltescu, Catalina

Journal:

Nature Genetics

Year:

2010

Language:

english

File:

PDF, 271 KB

english, 2010

11

Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

Melum, Espen, Franke, Andre, Schramm, Christoph, Weismüller, Tobias J, Gotthardt, Daniel Nils, Offner, Felix A, Juran, Brian D, Laerdahl, Jon K, Labi, Verena, Björnsson, Einar

Journal:

Nature Genetics

Year:

2010

Language:

english

File:

PDF, 350 KB

english, 2010

12

Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia

Goodman, Patricia A, Burkhardt, Nicole, Juran, Brian, Tibbles, Heather E, Uckun, Faith M

Journal:

Year:

2003

Language:

english

File:

PDF, 310 KB

english, 2003

13

Primary Biliary Cirrhosis Associated with HLA, IL12A, and IL12RB2 Variants

Hirschfield, Gideon M., Liu, Xiangdong, Xu, Chun, Lu, Yue, Xie, Gang, Lu, Yan, Gu, Xiangjun, Walker, Erin J., Jing, Kaiyan, Juran, Brian D.

Journal:

Boston Medical and Surgical Journal

Year:

2009

Language:

english

File:

PDF, 1.11 MB

english, 2009

14

Update on the genetics and genomics of PBC

Brian D. Juran, Konstantinos N. Lazaridis

Journal:

Journal of Autoimmunity

Year:

2010

Language:

english

File:

PDF, 210 KB

english, 2010

15

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

Trine Folseraas, Espen Melum, Philipp Rausch, Brian D. Juran, Eva Ellinghaus, Alexey Shiryaev, Jon K. Laerdahl, David Ellinghaus, Christoph Schramm, Tobias J. Weismüller, Daniel Nils Gotthardt, Johann

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 1.26 MB

english, 2012

16

American Gastroenterological Association Future Trends Committee Report: The Application of Genomic and Proteomic Technologies to Digestive Disease Diagnosis and Treatment and Their Likely Impact on Gastroenterology Clinical Practice

Konstantinos N. Lazaridis, Brian D. Juran

Journal:

Gastroenterology

Year:

2005

Language:

english

File:

PDF, 848 KB

english, 2005

17

Primary Biliary Cirrhosis Is Associated With a Genetic Variant in the 3′ Flanking Region of the CTLA4 Gene

Brian D. Juran, Elizabeth J. Atkinson, Erik M. Schlicht, Brooke L. Fridley, Konstantinos N. Lazaridis

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 156 KB

english, 2008

18

638 Genetic Polymorphisms in the COX2 and Wrap53 Genes Are Associated With Risk but Not Survival of Cholangiocarcinoma

Aboelsoud, Mohammed M., Chaiteerakij, Roongruedee, Giama, Nasra H., Moser, Catherine D., Baichoo, Esha, Mettler, Teresa A., Juran, Brian D., Harmsen, William S., Therneau, Terry M., Lazaridis, Konstan

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 494 KB

english, 2014

19

630 Coffee Consumption Is Associated With Reduced Risk of Primary Sclerosing Cholangitis but Not Primary Biliary Cirrhosis

Lammert, Craig, Juran, Brian D., Schlicht, Erik, Xie, Xiao, Atkinson, Elizabeth J., de Andrade, Mariza, Lazaridis, Konstantinos

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 307 KB

english, 2013

20

212 Exome Sequencing in Families Identifies Rare Variants in Cell Junction Associated Proteins Representing a Potential Link Between Genetic Variation and Liver-Targeted Autoimmunity in Primary Biliary Cirrhosis

Juran, Brian D., Klee, Eric W., Li, Ying, Schlicht, Erik, Lazaridis, Konstantinos

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 53 KB

english, 2013

21

696 Lack of Association Between NKG2D Polymorphisms and Cholangiocarcinoma (CCA) Risk in Primary Sclerosing Cholangitis (PSC) and Non-PSC Patients

Chaiteerakij, Roongruedee, Juran, Brian D., Moser, Catherine D., Mettler, Teresa A., Lazaridis, Konstantinos, Roberts, Lewis R.

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 176 KB

english, 2012

22

Reduced Coffee Consumption Among Individuals With Primary Sclerosing Cholangitis but Not Primary Biliary Cirrhosis

Lammert, Craig, Juran, Brian D., Schlicht, Erik, Xie, Xiao, Atkinson, Elizabeth J., de Andrade, Mariza, Lazaridis, Konstantinos N.

Journal:

Clinical Gastroenterology and Hepatology

Year:

2014

Language:

english

File:

PDF, 301 KB

english, 2014

23

Genetics and Genomics of Primary Biliary Cirrhosis

Juran, Brian D., Lazaridis, Konstantinos N.

Journal:

Clinics in Liver Disease

Year:

2008

Language:

english

File:

PDF, 224 KB

english, 2008

24

The AmpliChip CYP450 Test: Principles, Challenges, and Future Clinical Utility in Digestive Disease

Juran, Brian D., Egan, Laurence J., Lazaridis, Konstantinos N.

Journal:

Clinical Gastroenterology and Hepatology

Year:

2006

Language:

english

File:

PDF, 309 KB

english, 2006

25

Genetics of Hepatobiliary Diseases

Juran, Brian D., Lazaridis, Konstantinos N.

Journal:

Clinical Gastroenterology and Hepatology

Year:

2006

Language:

english

File:

PDF, 250 KB

english, 2006

26

460 Interaction Between Genetic Variants of TNF and CTLA4 Increases the Risk of Primary Biliary Cirrhosis

Juran, Brian D., Atkinson, Elizabeth J., Schlicht, Erik M., Lazaridis, Konstantinos

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 71 KB

english, 2009

27

Failure to Notify Reportable Test Results: Significance in Medical Malpractice

Gale, Brian D., Bissett-Siegel, Dana P., Davidson, Steven J., Juran, David C.

Journal:

Journal of the American College of Radiology

Year:

2011

Language:

english

File:

PDF, 328 KB

english, 2011

28

Biochemical response to ursodeoxycholic acid predicts survival in a North American cohort of primary biliary cirrhosis patients

Lammert, Craig, Juran, Brian D., Schlicht, Erik, Chan, Landon L., Atkinson, Elizabeth J., de Andrade, Mariza, Lazaridis, Konstantinos N.

Journal:

Journal of Gastroenterology

Year:

2014

Language:

english

File:

PDF, 290 KB

english, 2014

29

Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease

Naess, Sigrid, Björnsson, Einar, Anmarkrud, Jarl A., Mamari, Said Al, Juran, Brian D., Lazaridis, Konstantinos N., Chapman, Roger, Bergquist, Annika, Melum, Espen, Marsh, Steven G. E., Schrumpf, Erik,

Journal:

Liver International

Year:

2014

Language:

english

File:

PDF, 148 KB

english, 2014

30

Common Genetic Variation and Haplotypes of the Anion Exchanger SLC4A2 in Primary Biliary Cirrhosis

Juran, Brian D, Atkinson, Elizabeth J, Larson, Joseph J, Schlicht, Erik M, Lazaridis, Konstantinos N

Journal:

American Journal of Gastroenterology

Year:

2009

Language:

english

File:

PDF, 131 KB

english, 2009

31

Association Between HLA Haplotypes and Increased Serum Levels of IgG4 in Patients With Primary Sclerosing Cholangitis

Berntsen, Natalie L., Klingenberg, Olav, Juran, Brian D., Benito de Valle, Maria, Lindkvist, Björn, Lazaridis, Konstantinos N., Boberg, Kirsten Muri, Karlsen, Tom H., Hov, Johannes Roksund

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 265 KB

english, 2015

32

Mo1000 A Comparative Study of Cholestatic Pruritus in Primary Biliary Cirrhosis Cohorts From USA, UK and Italy

Hegade, Vinod S., Mells, George, Lammert, Craig, Juran, Brian D., Lleo, Ana, Carbone, Marco, Lazaridis, Konstantinos, Invernizzi, Pietro, Kendrick, Stuart, Sandford, Richard, Hirschfield, Gideon, Jone

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

33

Mo1004 Predictors and Durability of Biochemical Response to Ursodeoxycholic Acid (UDCA) in Patients With Primary Biliary Cirrhosis (PBC): A Long-Term Follow-Up Study

Gulamhusein, Aliya, Larson, Joseph J., Juran, Brian D., Atkinson, Elizabeth J., Lammert, Craig, Lazaridis, Konstantinos

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 54 KB

english, 2015

34

Mo1001 Low Incidence of Primary Biliary Cirrhosis (PBC) in First Degree Relatives (FDRs) of Patients With PBC With Long Term Follow Up

Gulamhusein, Aliya, Juran, Brian D., Schlicht, Erik, Lazaridis, Konstantinos

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 335 KB

english, 2015

35

Environmental Factors in Primary Biliary Cirrhosis

Juran, Brian, Lazaridis, Konstantinos

Journal:

Seminars in Liver Disease

Year:

2014

Language:

english

File:

PDF, 165 KB

english, 2014

36

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

Cordell, Heather J., Han, Younghun, Mells, George F., Li, Yafang, Hirschfield, Gideon M., Greene, Casey S., Xie, Gang, Juran, Brian D., Zhu, Dakai, Qian, David C., Floyd, James A. B., Morley, Katherin

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 301 KB

english, 2015

37

Genomics in the Post-GWAS Era

Juran, Brian, Lazaridis, Konstantinos

Journal:

Seminars in Liver Disease

Year:

2011

File:

PDF, 166 KB

2011

38

Applying Genomics to the Study of Complex Disease

Juran, Brian, Lazaridis, Konstantinos

Journal:

Seminars in Liver Disease

Year:

2007

Language:

english

File:

PDF, 154 KB

english, 2007

39

Genomics in the Post-GWAS Era

Juran, Brian, Lazaridis, Konstantinos

Journal:

Seminars in Liver Disease

Year:

2011

Language:

english

File:

PDF, 166 KB

english, 2011

40

Genomic Studies of the Spleen Protein Tyrosine Kinase Locus Reveal a Complex Promoter Structure and Several Genetic Variants

Goodman, Patricia A., Juran, Brian, Wood, Carla M., Uckun, Fatih

Journal:

Leukemia and Lymphoma

Year:

2002

Language:

english

File:

PDF, 2.19 MB

english, 2002

41

Duration of Inflammatory Bowel Disease Is Associated With Increased Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis and IBD

Gulamhusein, Aliya F, Eaton, John E, Tabibian, James H, Atkinson, Elizabeth J, Juran, Brian D, Lazaridis, Konstantinos N

Journal:

American Journal of Gastroenterology

Year:

2016

Language:

english

File:

PDF, 282 KB

english, 2016

42

Genome-Wide Association Studies in Primary Biliary Cirrhosis

Gulamhusein, Aliya, Juran, Brian, Lazaridis, Konstantinos

Journal:

Seminars in Liver Disease

Year:

2015

Language:

english

File:

PDF, 394 KB

english, 2015

43

Low Incidence of Primary Biliary Cirrhosis (PBC) in First Degree Relatives of PBC Probands after 8 Years of Follow Up

Gulamhusein, Aliya F., Juran, Brian D., Atkinson, Elizabeth J., McCauley, Bryan, Schlicht, Erik, Lazaridis, Konstantinos N.

Journal:

Liver International

Year:

2016

Language:

english

File:

PDF, 216 KB

english, 2016

44

Association between variants in inflammation and cancer-associated genes and risk and survival of cholangiocarcinoma

Chaiteerakij, Roongruedee, Juran, Brian D., Aboelsoud, Mohammed M., Harmsen, William S., Moser, Catherine D., Giama, Nasra H., Allotey, Loretta K., Mettler, Teresa A., Baichoo, Esha, Zhang, Xiaodan, T

Journal:

Cancer Medicine

Year:

2015

Language:

english

File:

PDF, 65 KB

english, 2015

45

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

Ji, Sun-Gou, Juran, Brian D, Mucha, Sören, Folseraas, Trine, Jostins, Luke, Melum, Espen, Kumasaka, Natsuhiko, Atkinson, Elizabeth J, Schlicht, Erik M, Liu, Jimmy Z, Shah, Tejas, Gutierrez-Achury, Jav

Journal:

Nature Genetics

Year:

2016

Language:

english

File:

PDF, 493 KB

english, 2016

46

Variations in Primary Sclerosing Cholangitis Across the Age Spectrum

Eaton, John E, McCauley, Bryan M, Atkinson, Elizabeth J, Juran, Brian D, Schlicht, Erik M, de Andrade, Mariza, Lazaridis, Konstantinos N

Journal:

Journal of Gastroenterology and Hepatology

Year:

2017

Language:

english

File:

PDF, 457 KB

english, 2017

47

Doublecortin domain containing protein 2 (DCDC2) genetic variants in primary sclerosing cholangitis

Cheung, Angela C., Juran, Brian D., Moore, Raymond M., LaRusso, Nicholas F., Lazaridis, Konstantinos N.

Journal:

Journal of Hepatology

Year:

2017

Language:

english

File:

PDF, 407 KB

english, 2017

48

External validation of the United Kingdom-primary biliary cholangitis risk scores of patients with primary biliary cholangitis treated with ursodeoxycholic acid

Cheung, Angela C., Gulamhusein, Aliya F., Juran, Brian D., Schlicht, Erik M., McCauley, Bryan M., de Andrade, Mariza, Atkinson, Elizabeth J., Lazaridis, Konstantinos N.

Journal:

Hepatology Communications

Year:

2018

Language:

english

File:

PDF, 239 KB

english, 2018

49

Primary Sclerosing Cholangitis Risk Estimate Tool (PREsTo) Predicts Outcomes in PSC: A Derivation & Validation Study Using Machine Learning

Eaton, John E., Vesterhus, Mette, McCauley, Bryan M., Atkinson, Elizabeth J., Schlicht, Erik M., Juran, Brian D., Gossard, Andrea A., LaRusso, Nicholas F., Gores, Gregory J., Karlsen, Tom H., Lazaridi

Journal:

Year:

2018

Language:

english

File:

PDF, 1.05 MB

english, 2018

50

Standardization and Comparison of an XTT-Based TNF-α Bioassay with a TNF-α ELISA

Turtinen, Lloyd W., Juran, Brian D.

Journal:

Year:

1998

Language:

english

File:

PDF, 239 KB

english, 1998

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