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1

The WNT signaling pathways in wound healing and fibrosis

Burgy, Olivier, Königshoff, Melanie

Journal:

Year:

2018

Language:

english

File:

PDF, 2.43 MB

english, 2018

2

Protease-Mediated Release of Chemotherapeutics from Mesoporous Silica Nanoparticles to ex Vivo Human and Mouse Lung Tumors

van Rijt, Sabine H., Bölükbas, Deniz A., Argyo, Christian, Datz, Stefan, Lindner, Michael, Eickelberg, Oliver, Königshoff, Melanie, Bein, Thomas, Meiners, Silke

Journal:

Year:

2015

Language:

english

File:

PDF, 988 KB

english, 2015

3

Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis

Ota, Chiharu, Ng-Blichfeldt, John-Poul, Korfei, Martina, Alsafadi, Hani N., Lehmann, Mareike, Skronska-Wasek, Wioletta, M. De Santis, Martina, Guenther, Andreas, Wagner, Darcy E., Königshoff, Melanie

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 8.47 MB

english, 2018

4

Human lung stem cells: Oh, the places you'll go!

Melanie Königshoff, Johannes Schwarz, Oliver Eickelberg

Journal:

EMBO Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 259 KB

english, 2011

5

Cross-breeding experiments among different populations of the ‘cosmopolitan’ speciesPhyllognathopus viguieri(Copepoda: Harpacticoida)

Thomas Glatzel, Dagmar Königshoff

Journal:

Year:

2005

Language:

english

File:

PDF, 275 KB

english, 2005

6

Mating behaviour of the ‘cosmopolitan’ species Phyllognathopus viguieri (Copepoda: Harpacticoida) and its systematical significance

D. Königshoff, T. Glatzel

Journal:

Journal of Zoological Systematics and Evolutionary Research

Year:

2008

Language:

english

File:

PDF, 417 KB

english, 2008

7

Plasminogen activator inhibitor type 1 inhibits smooth muscle cell proliferation in pulmonary arterial hypertension

Fotini M. Kouri, Markus A. Queisser, Melanie Königshoff, Izabella Chrobak, Klaus T. Preissner, Werner Seeger, Oliver Eickelberg

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2008

Language:

english

File:

PDF, 841 KB

english, 2008

8

WNT1 inducible signaling pathway protein 1 (WISP1): A novel mediator linking development and disease

Barbara Berschneider, Melanie Königshoff

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2011

Language:

english

File:

PDF, 370 KB

english, 2011

9

From molecule to man: Integrating molecular biology with whole organ physiology in studying respiratory disease

Melanie Königshoff, Franziska Uhl, Reinoud Gosens

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 303 KB

english, 2011

10

The WNT signaling pathway from ligand secretion to gene transcription: Molecular mechanisms and pharmacological targets

Baarsma, Hoeke A., Königshoff, Melanie, Gosens, Reinoud

Journal:

Pharmacology & Therapeutics

Year:

2013

Language:

english

File:

PDF, 774 KB

english, 2013

11

Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis

Sevdalina Nikolova, Andreas Guenther, Rajkumar Savai, Norbert Weissmann, Hossein A Ghofrani, Melanie Konigshoff, Oliver Eickelberg, Walter Klepetko, Robert Voswinckel, Werner Seeger, Friedrich Grimmin

Journal:

Respiratory Research

Year:

2010

Language:

english

File:

PDF, 3.63 MB

english, 2010

12

WNT/β-Catenin Signaling Induces IL-1β Expression by Alveolar Epithelial Cells in Pulmonary Fibrosis

Aumiller, Verena, Balsara, Nisha, Wilhelm, Jochen, Günther, Andreas, Königshoff, Melanie

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 2.02 MB

english, 2013

13

Considerations for Targeting β-Catenin Signaling in Fibrosis

Gottardi, Cara J., Königshoff, Melanie

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2013

Language:

english

File:

PDF, 150 KB

english, 2013

14

Paired Immunoglobulin-Like Receptor–B Inhibits Pulmonary Fibrosis by Suppressing Profibrogenic Properties of Alveolar Macrophages

Karo-Atar, Danielle, Moshkovits, Itay, Eickelberg, Oliver, Königshoff, Melanie, Munitz, Ariel

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.29 MB

english, 2013

15

Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease

Krauss-Etschmann, S., Bush, A., Bellusci, S., Brusselle, G. G., Dahlen, S. E. K., Dehmel, S., Eickelberg, O., Gibson, G., Hylkema, M. N., Knaus, P., Konigshoff, M., Lloyd, C. M., Macciarini, P., Maill

Journal:

Year:

2013

Language:

english

File:

PDF, 196 KB

english, 2013

16

miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis

Berschneider, Barbara, Ellwanger, Daniel C., Baarsma, Hoeke A., Thiel, Cedric, Shimbori, Chiko, White, Eric S., Kolb, Martin, Neth, Peter, Königshoff, Melanie

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2014

Language:

english

File:

PDF, 1.73 MB

english, 2014

17

Transforming Growth Factor- Signaling across Ages: From Distorted Lung Development to Chronic Obstructive Pulmonary Disease

Morty, R. E, Konigshoff, M., Eickelberg, O.

Journal:

Proceedings of the American Thoracic Society

Year:

2009

Language:

english

File:

PDF, 1018 KB

english, 2009

18

Cigarette smoke extract affects mitochondrial function in alveolar epithelial cells

Ballweg, K., Mutze, K., Konigshoff, M., Eickelberg, O., Meiners, S.

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2014

Language:

english

File:

PDF, 1.75 MB

english, 2014

19

Live and Let Die: Targeting Alveolar Epithelial Cell Proliferation in Pulmonary Fibrosis

Königshoff, Melanie, Bonniaud, Philippe

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2014

Language:

english

File:

PDF, 434 KB

english, 2014

20

Hallmarks of the ageing lung

Meiners, S., Eickelberg, O., Konigshoff, M.

Journal:

European Respiratory Journal

Year:

2015

Language:

english

File:

PDF, 872 KB

english, 2015

21

Transgelin is a direct target of TGF- /Smad3-dependent epithelial cell migration in lung fibrosis

Yu, H., Konigshoff, M., Jayachandran, A., Handley, D., Seeger, W., Kaminski, N., Eickelberg, O.

Journal:

The FASEB Journal

Year:

2008

Language:

english

File:

PDF, 968 KB

english, 2008

22

The new Back to Basics section: emerging concepts in basic and translational medicine

Journal:

European Respiratory Journal

Year:

2014

Language:

english

File:

PDF, 272 KB

english, 2014

23

Dickkopf proteins influence lung epithelial cell proliferation in idiopathic pulmonary fibrosis

Pfaff, E.-M., Becker, S., Gunther, A., Konigshoff, M.

Journal:

European Respiratory Journal

Year:

2011

Language:

english

File:

PDF, 1.06 MB

english, 2011

24

Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention

Konigshoff, M., Dumitrascu, R., Udalov, S., Amarie, O. V., Reiter, R., Grimminger, F., Seeger, W., Schermuly, R. T., Eickelberg, O.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.23 MB

english, 2010

25

SNAI transcription factors mediate epithelial-mesenchymal transition in lung fibrosis

Jayachandran, A, Konigshoff, M, Yu, H, Rupniewska, E, Hecker, M, Klepetko, W, Seeger, W, Eickelberg, O

Journal:

Year:

2009

Language:

english

File:

PDF, 2.00 MB

english, 2009

26

Wnt-inducible protein (WISP-1) is a key regulator of alveolar epithelial cell hyperplasia in pulmonary fibrosis

Konigshoff, M., Wilhelm, J., Jahn, A., Amarie, O., Kitowska, K., Wilhelm, A., Bohle, RainerM., Seeger, W., Rose, F., Fink, L., Guenther, A., Eickelberg, O.

Journal:

European Respiratory Review

Year:

2006

Language:

english

File:

PDF, 139 KB

english, 2006

27

Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures

Uhl, F. E., Vierkotten, S., Wagner, D. E., Burgstaller, G., Costa, R., Koch, I., Lindner, M., Meiners, S., Eickelberg, O., Konigshoff, M.

Journal:

European Respiratory Journal

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

28

HER-2/neu Gene Copy Number Quantified by Real-Time PCR: Comparison of Gene Amplification, Heterozygosity, and Immunohistochemical Status in Breast Cancer Tissue

Journal:

Clinical Chemistry

Year:

2003

Language:

english

File:

PDF, 280 KB

english, 2003

29

In search of the fibrotic epithelial cell: opportunities for a collaborative network

Jenkins, G., Blanchard, A., Borok, Z., Bradding, P., Ehrhardt, C., Fisher, A., Hirani, N., Johnson, S., Konigshoff, M., Maher, T. M., Millar, A., Parfrey, H., Scotton, C., Tetley, T., Thickett, D., Wo

Journal:

Year:

2012

Language:

english

File:

PDF, 95 KB

english, 2012

30

[American Thoracic Society American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California - ()] A13. INSIGHTS IN COPD PATHOGENESIS - Expression and Activity of Wnt/beta-Catenin Signalling in COPD.

Kneidinger, N, Konigshoff, M, Becker, S, Eickelberg, O

Year:

2009

Language:

english

File:

PDF, 116 KB

english, 2009

31

Immune system dysregulation in chronic lung disease

Marsland, B. J., Konigshoff, M., Saglani, S., Eickelberg, O.

Journal:

European Respiratory Journal

Year:

2011

Language:

english

File:

PDF, 212 KB

english, 2011

32

Lung Cancer in Pulmonary Fibrosis: Tales of Epithelial Cell Plasticity

Königshoff, Melanie

Journal:

Year:

2011

Language:

english

File:

PDF, 179 KB

english, 2011

33

Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis

Zhou, Q., Pardo, A., Konigshoff, M., Eickelberg, O., Budinger, G. R. S., Thavarajah, K., Gottardi, C. J., Jones, J., Varga, J., Selman, M., Sznajder, J. I., Raj, J. U., Zhou, G.

Journal:

The FASEB Journal

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

34

Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats

Dumitrascu, R., Kulcke, C., Konigshoff, M., Kouri, F., Yang, X., Morrell, N., Ghofrani, H. A., Weissmann, N., Reiter, R., Seeger, W., Grimminger, F., Eickelberg, O., Schermuly, R. T., Pullamsetti, S.

Journal:

European Respiratory Journal

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

35

Wnt Pathway Activation in Long Term Remnant Rat Model

Banon-Maneus, E., Rovira, J., Ramirez-Bajo, M. J., Moya-Rull, D., Hierro-Garcia, N., Takenaka, S., Diekmann, F., Eickelberg, O., Königshoff, M., Campistol, J. M.

Journal:

BioMed Research International

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

36

Functional role and species-specific contribution of arginases in pulmonary fibrosis

Kitowska, Kamila, Zakrzewicz, Dariusz, Königshoff, Melanie, Chrobak, Izabella, Grimminger, Friedrich, Seeger, Werner, Bulau, Patrick, Eickelberg, Oliver

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2008

Language:

english

File:

PDF, 2.07 MB

english, 2008

37

Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension

Costello, C. M., Howell, K., Cahill, E., McBryan, J., Konigshoff, M., Eickelberg, O., Gaine, S., Martin, F., McLoughlin, P.

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2008

Language:

english

File:

PDF, 1.13 MB

english, 2008

38

Rebuilding a diseased lung: repair and regeneration

Konigshoff, M., Saglani, S., Marsland, B. J., Eickelberg, O.

Journal:

European Respiratory Journal

Year:

2013

Language:

english

File:

PDF, 128 KB

english, 2013

39

CARM1 Regulates Alveolar Epithelial Senescence and Elastase-induced Emphysema Susceptibility

Sarker, Rim S.J., John-Schuster, Gerrit, Bohla, Alexander, Mutze, Kathrin, Burgstaller, Gerald, Bedford, Mark T, Königshoff, Melanie, Eickelberg, Oliver, Yildirim, Ali Ö

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 1.54 MB

english, 2015

40

WNT Signaling in Lung Disease

Königshoff, Melanie, Eickelberg, Oliver

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 457 KB

english, 2010

41

Shroom expression is attenuated in pulmonary arterial hypertension

Sevilla-Perez, J., Konigshoff, M., Kwapiszewska, G., Amarie, O. V., Seeger, W., Weissmann, N., Schermuly, R. T., Morty, R. E., Eickelberg, O.

Journal:

European Respiratory Journal

Year:

2008

Language:

english

File:

PDF, 502 KB

english, 2008

42

The Role of Dimethylarginine Dimethylaminohydrolase in Idiopathic Pulmonary Fibrosis

Pullamsetti, S. S., Savai, R., Dumitrascu, R., Dahal, B. K., Wilhelm, J., Konigshoff, M., Zakrzewicz, D., Ghofrani, H. A., Weissmann, N., Eickelberg, O., Guenther, A., Leiper, J., Seeger, W., Grimming

Journal:

Science Translational Medicine

Year:

2011

Language:

english

File:

PDF, 2.13 MB

english, 2011

43

Thrombin Impairs Alveolar Fluid Clearance by Promoting Endocytosis of Na + ,K + -ATPase

Vadász, István, Morty, Rory E., Olschewski, Andrea, Königshoff, Melanie, Kohstall, Markus G., Ghofrani, Hossein A., Grimminger, Friedrich, Seeger, Werner

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 440 KB

english, 2005

44

The Angiotensin II Receptor 2 Is Expressed and Mediates Angiotensin II Signaling in Lung Fibrosis

Königshoff, Melanie, Wilhelm, Anke, Jahn, Andreas, Sedding, Daniel, Amarie, Oana Veronica, Eul, Bastian, Seeger, Werner, Fink, Ludger, Günther, Andreas, Eickelberg, Oliver, Rose, Frank

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.35 MB

english, 2007

45

Loss of RAGE in Pulmonary Fibrosis

Queisser, Markus A., Kouri, Fotini M., Königshoff, Melanie, Wygrecka, Malgorzata, Schubert, Uwe, Eickelberg, Oliver, Preissner, Klaus T.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 917 KB

english, 2008

46

Galectin-3: The Bridge over Troubled Waters

Königshoff, Melanie, Rojas, Mauricio

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2012

Language:

english

File:

PDF, 68 KB

english, 2012

47

Multidimensional immunolabeling and 4D time-lapse imaging of vital ex vivo lung tissue

Burgstaller, Gerald, Vierkotten, Sarah, Lindner, Michael, Königshoff, Melanie, Eickelberg, Oliver

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2015

Language:

english

File:

PDF, 3.31 MB

english, 2015

48

Endogenous Lung Regeneration

Rock, Jason, Königshoff, Melanie

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2012

Language:

english

File:

PDF, 481 KB

english, 2012

49

Pulmonary Epithelium Is a Prominent Source of Proteinase-activated Receptor-1–inducible CCL2 in Pulmonary Fibrosis

Mercer, Paul F., Johns, Robin H., Scotton, Chris J., Krupiczojc, Malvina A., Königshoff, Melanie, Howell, David C. J., McAnulty, Robin J., Das, Anuk, Thorley, Andrew J., Tetley, Terry D., Eickelberg,

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2009

Language:

english

File:

PDF, 1.50 MB

english, 2009

50

Enolase 1 (ENO1) and protein disulfide-isomerase associated 3 (PDIA3) regulate Wnt/ -catenin-driven trans-differentiation of murine alveolar epithelial cells

Mutze, K., Vierkotten, S., Milosevic, J., Eickelberg, O., Konigshoff, M.

Journal:

Disease Models & Mechanisms

Year:

2015

Language:

english

File:

PDF, 2.11 MB

english, 2015