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51

Caspase recruitment domain of procaspase-2 could be a target for SUMO-1 modification through Ubc9

Hiromi Shirakura, Naoko Hayashi, Shin-ichi Ogino, Kazuhiro Tsuruma, Takashi Uehara, Yasuyuki Nomura

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 715 KB

english, 2005

52

Nuclear retention of STAT3 through the coiled-coil domain regulates its activity

Noriko Sato, Rieko Tsuruma, Seiyu Imoto, Yuichi Sekine, Ryuta Muromoto, Kenji Sugiyama, Tadashi Matsuda

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 464 KB

english, 2005

53

Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection

Kenichi Kakefuda, Yasunori Fujita, Atsushi Oyagi, Kana Hyakkoku, Toshio Kojima, Ken Umemura, Kazuhiro Tsuruma, Masamitsu Shimazawa, Masafumi Ito, Yoshinori Nozawa, Hideaki Hara

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 1.69 MB

english, 2009

54

Edaravone-loaded liposomes for retinal protection against oxidative stress-induced retinal damage

Kohei Hironaka, Yuta Inokuchi, Takuya Fujisawa, Hiroki Shimazaki, Mai Akane, Yuichi Tozuka, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara, Hirofumi Takeuchi

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2011

Language:

english

File:

PDF, 956 KB

english, 2011

55

Oral administration of crocetin prevents inner retinal damage induced by N-methyl-d-aspartate in mice

Yuta Ohno, Tomohiro Nakanishi, Naofumi Umigai, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara

Journal:

European Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 636 KB

english, 2012

56

Ruboxistaurin, a PKCβ inhibitor, inhibits retinal neovascularization via suppression of phosphorylation of ERK1/2 and Akt

Shinsuke Nakamura, Yuichi Chikaraishi, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara

Journal:

Experimental Eye Research

Year:

2010

Language:

english

File:

PDF, 922 KB

english, 2010

57

Ubiquilin interacts with ubiquitylated proteins and proteasome through its ubiquitin-associated and ubiquitin-like domains

Han Seok Ko, Takashi Uehara, Kazuhiro Tsuruma, Yasuyuki Nomura

Journal:

Year:

2004

Language:

english

File:

PDF, 218 KB

english, 2004

58

GMEB1, a novel endogenous caspase inhibitor, prevents hypoxia- and oxidative stress-induced neuronal apoptosis

Tadashi Nakagawa, Kazuhiro Tsuruma, Takashi Uehara, Yasuyuki Nomura

Journal:

Neuroscience Letters

Year:

2008

Language:

english

File:

PDF, 219 KB

english, 2008

59

Cilostazol protects against hemorrhagic transformation in mice transient focal cerebral ischemia-induced brain damage

Yuko Nonaka, Kazuhiro Tsuruma, Masamitsu Shimazawa, Shinichi Yoshimura, Toru Iwama, Hideaki Hara

Journal:

Neuroscience Letters

Year:

2009

Language:

english

File:

PDF, 836 KB

english, 2009

60

Metallothionein-3 deficient mice exhibit abnormalities of psychological behaviors

Akihiro Koumura, Kenichi Kakefuda, Akiko Honda, Yasushi Ito, Kazuhiro Tsuruma, Masamitsu Shimazawa, Yoko Uchida, Isao Hozumi, Masahiko Satoh, Takashi Inuzuka, Hideaki Hara

Journal:

Neuroscience Letters

Year:

2009

Language:

english

File:

PDF, 299 KB

english, 2009

61

SUN N8075, a novel radical scavenger, protects against retinal cell death in mice

Mai Akane, Masamitsu Shimazawa, Yuta Inokuchi, Kazuhiro Tsuruma, Hideaki Hara

Journal:

Neuroscience Letters

Year:

2011

Language:

english

File:

PDF, 539 KB

english, 2011

62

Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia

K. Hyakkoku, J. Hamanaka, K. Tsuruma, M. Shimazawa, H. Tanaka, S. Uematsu, S. Akira, N. Inagaki, H. Nagai, H. Hara

Journal:

Year:

2010

Language:

english

File:

PDF, 1.86 MB

english, 2010

63

Forebrain specific heparin-binding epidermal growth factor-like growth factor knockout mice show exacerbated ischemia and reperfusion injury

A. Oyagi, N. Morimoto, J. Hamanaka, M. Ishiguro, K. Tsuruma, M. Shimazawa, H. Hara

Journal:

Year:

2011

Language:

english

File:

PDF, 1.94 MB

english, 2011

64

A broad-spectrum matrix metalloproteinase inhibitor prevents hemorrhagic complications induced by tissue plasminogen activator in mice

K. Mishiro, M. Ishiguro, Y. Suzuki, K. Tsuruma, M. Shimazawa, H. Hara

Journal:

Year:

2012

Language:

english

File:

PDF, 854 KB

english, 2012

65

A Rho kinase (ROCK) inhibitor, fasudil, prevents matrix metalloproteinase-9-related hemorrhagic transformation in mice treated with tissue plasminogen activator

M. Ishiguro, K. Kawasaki, Y. Suzuki, F. Ishizuka, K. Mishiro, Y. Egashira, I. Ikegaki, K. Tsuruma, M. Shimazawa, S. Yoshimura, T. Iwama, H. Hara

Journal:

Year:

2012

Language:

english

File:

PDF, 870 KB

english, 2012

66

Synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin reduces hepatic ischemia-reperfusion injury in rats

T. Tsuruma, H. Sahara, M. Takenouchi, A. Yagihashi, Y. Iwayama, H. Shima, T. Furuhata, T. Torigoe, S. Hanashima, T. Yamazaki, F. Sugawara, Y. Mizushina, K. Ohta, K. Sakaguchi, N. Sato, K. Hirata

Journal:

Transplantation Proceedings

Year:

2004

Language:

english

File:

PDF, 369 KB

english, 2004

67

Treatment with β-SQAG9 prevents rat hepatic ischemia-reperfusion injury

H. Shima, T. Tsuruma, H. Sahara, M. Takenouchi, N. Takahashi, Y. Iwayama, A. Yagihashi, N. Watanabe, N. Sato, K. Hirata

Journal:

Transplantation Proceedings

Year:

2005

Language:

english

File:

PDF, 254 KB

english, 2005

68

Heat-shock protein-73 protects against small intestinal warm ischemiareperfusion injury in the rat

Tetsuhiro Tsuruma, Atsuhito Yagihashi, Naoki Watanabe, Tomomi Yajima, Hidekazu Kameshima, Jun Araya, Koichi Hirata

Journal:

Year:

1999

Language:

english

File:

PDF, 345 KB

english, 1999

69

Induction of heat shock protein-70 (hsp-70) reduces preservation injury in rat IEC-18 intestinal epithelial cells

J Araya, T Tsuruma, K Hirata, A Yagihashi, T Katsuramaki, K Tarumi, Y Yanai, N Watanabe

Journal:

Transplantation Proceedings

Year:

2000

Language:

english

File:

PDF, 132 KB

english, 2000

70

Induction of heat shock protein-70 (hsp-70) by intraarterial administration of geranylgeranylacetone

T Tsuruma, A Yagihashi, K Hirata, J Araya, T Katsuramaki, K Tarumi, Y Yanai, N Watanabe

Journal:

Transplantation Proceedings

Year:

2000

Language:

english

File:

PDF, 490 KB

english, 2000

71

CTLA-4IG treatment induces long-term acceptance of rat small bowel allografts

K Tarumi, A Yagihashi, T Tsuruma, J Araya, K Hirata

Journal:

Transplantation Proceedings

Year:

2000

Language:

english

File:

PDF, 231 KB

english, 2000

72

Downregulation of cytokine-induced neutrophil chemoattractants and reduction of reperfusion injury in liver allograft by interleukin-10

A Yagihashi, K Hirata, X.M Zou, T Tsuruma, J Araya, T Yajima, H Kameshima, Y Yanai, M Nakamura, Y Wada, K Asanuma, N Watanabe

Journal:

Transplantation Proceedings

Year:

2000

Language:

english

File:

PDF, 58 KB

english, 2000

73

The regulation of HGF and TGF-β by an angiotensin II type 1 receptor antagonist in hepatic ischemia-reperfusion injury

J Araya, T Tsuruma, K Hirata, A Yagihashi, M Meguro, M Kawakami, Y Yanai, N Watanabe

Journal:

Transplantation Proceedings

Year:

2003

Language:

english

File:

PDF, 334 KB

english, 2003

74

Induction of heat-shock protein protects the small intestine from preservation injury

A. Yagihashi, K. Tarumi, T. Tsuruma, T. Yajima, K. Kameshima, Y. Yanai, S. Koide, N. Watanabe, K. Hirata

Journal:

Transplantation Proceedings

Year:

1998

Language:

english

File:

PDF, 223 KB

english, 1998

75

Anti-rat IL-8 (CINC) monoclonal antibody administration reduces ischemia-reperfusion injury in small intestine

T Tsuruma, A Yagihashi, K Tarumi, K Hirata

Journal:

Transplantation Proceedings

Year:

1998

Language:

english

File:

PDF, 252 KB

english, 1998

76

Heat shock protein improves cold preserved small bowel grafts

K Tarumi, A Yagihashi, T Tsuruma, T Sakawaki, K.S Sasaki, K Hirata

Journal:

Transplantation Proceedings

Year:

1998

Language:

english

File:

PDF, 576 KB

english, 1998

77

Induction of heat shock protein-73 reduces ischemia-reperfusion injury in rat small intestine

T Tsuruma, A Yagihashi, K Tarumi, K Sasaki, N Watanabe, K Hirata

Journal:

Transplantation Proceedings

Year:

1998

Language:

english

File:

PDF, 309 KB

english, 1998

78

Early evaluation of graft viability using hepatic venous oxygen saturation in pig liver transplantation

T Katsuramaki, T Matsuno, K Hirata, M Isobe, F Sato, T Tsuruma, K Tarumi, A Yagihashi, K Sasaki

Journal:

Transplantation Proceedings

Year:

1998

Language:

english

File:

PDF, 137 KB

english, 1998

79

Geranylgeranylacetone induces heat shock protein-73 in rat small intestine

T Tsuruma, A Yagihashi, S Koide, J Araya, K Tarumi, N Watanabe, K Hirata

Journal:

Transplantation Proceedings

Year:

1999

Language:

english

File:

PDF, 106 KB

english, 1999

80

Induction and maintenance of tolerance by CTLA-4IG in rat small bowel allografts

K Tarumi, A Yagihashi, T Tsuruma, S Koide, K Sasaki, K Hirata

Journal:

Transplantation Proceedings

Year:

1999

Language:

english

File:

PDF, 116 KB

english, 1999

81

Lomerizine, a Ca2+ Channel Blocker, Protects against Neuronal Degeneration within the Visual Center of the Brain after Retinal Damage in Mice

Yasushi Ito, Shinsuke Nakamura, Hirotaka Tanaka, Kazuhiro Tsuruma, Masamitsu Shimazawa, Makoto Araie, Hideaki Hara

Journal:

CNS Neuroscience & Therapeutics

Year:

2010

Language:

english

File:

PDF, 606 KB

english, 2010

82

Apoptosis-Inducing Factor and Cyclophilin A Cotranslocate to the Motor Neuronal Nuclei in Amyotrophic Lateral Sclerosis Model Mice

Hirotaka Tanaka, Hiroki Shimazaki, Masataka Kimura, Hiroshi Izuta, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara

Journal:

CNS Neuroscience & Therapeutics

Year:

2011

Language:

english

File:

PDF, 697 KB

english, 2011

83

Laxative effects and mechanism of action of Brazilian green propolis

Mamoru Kakino, Hiroshi Izuta, Kazuhiro Tsuruma, Yoko Araki, Masamitsu Shimazawa, Kenji Ichihara, Hideaki Hara

Journal:

BMC Complementary and Alternative Medicine

Year:

2012

Language:

english

File:

PDF, 391 KB

english, 2012

84

P.2.f.001 Mania-like behavioural abnormalities of diacylglycerol kinase β knockout mice

K. Kakefuda, A. Oyagi, K. Tsuruma, M. Shimazawa, K. Yokota, Y. Shirai, K. Horie, N. Saito, J. Takeda, H. Hara

Journal:

European Neuropsychopharmacology

Year:

2009

Language:

english

File:

PDF, 104 KB

english, 2009

85

P.1.d.008 Diacylglycerol kinase β knockout mice show an abnormal response on psychostimulant-induced behavioural change

H. Hara, K. Kakefuda, M. Ishisaka, A. Oyagi, K. Tsuruma, M. Shimazawa, K. Yokota, N. Saito, K. Fukunaga, J. Takeda

Journal:

European Neuropsychopharmacology

Year:

2010

Language:

english

File:

PDF, 48 KB

english, 2010

86

Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes

Akari Takahashi, Toshihiko Torigoe, Yasuaki Tamura, Takayuki Kanaseki, Tomohide Tsukahara, Yasushi Sasaki, Hidekazu Kameshima, Tetsuhiro Tsuruma, Koichi Hirata, Takashi Tokino, Yoshihiko Hirohashi, No

Journal:

Cell Stress and Chaperones

Year:

2012

Language:

english

File:

PDF, 407 KB

english, 2012

87

Preferential involvement of Na+/Ca2+ exchanger type-1 in the brain damage caused by transient focal cerebral ischemia in mice

Nobutaka Morimoto, Satomi Kita, Masamitsu Shimazawa, Hiroko Namimatsu, Kazuhiro Tsuruma, Kazuhide Hayakawa, Kenichi Mishima, Nobuaki Egashira, Takuya Iyoda, Ichiro Horie, Yusuke Gotoh, Katsunori Iwasa

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 577 KB

english, 2012

88

Imipramine protects mouse hippocampus against tunicamycin-induced cell death

Yoko Ono, Masamitsu Shimazawa, Mitsue Ishisaka, Atsushi Oyagi, Kazuhiro Tsuruma, Hideaki Hara

Journal:

European Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 626 KB

english, 2012

89

Immunotherapeutic benefit of α-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients

Kameshima, Hidekazu, Tsuruma, Tetsuhiro, Kutomi, Goro, Shima, Hiroaki, Iwayama, Yuji, Kimura, Yasutoshi, Imamura, Masahumi, Torigoe, Toshihiko, Takahashi, Akari, Hirohashi, Yoshihiko, Tamura, Yasuaki,

Journal:

Year:

2013

Language:

english

File:

PDF, 305 KB

english, 2013

90

Phase I clinical study of anti-apoptosis protein, survivin-derived peptide vaccine therapy for patients with advanced or recurrent colorectal cancer

Tetsuhiro Tsuruma, Fumitake Hata, Toshihiko Torigoe, Tomohisa Furuhata, Satomi Idenoue, Takehiro Kurotaki, Masaaki Yamamoto, Atsuhito Yagihashi, Tosei Ohmura, Koji Yamaguchi, Tadashi Katsuramaki, Taka

Journal:

Journal of Translational Medicine

Year:

2004

Language:

english

File:

PDF, 832 KB

english, 2004

91

Clinical and immunological evaluation of anti-apoptosis protein, survivin-derived peptide vaccine in phase I clinical study for patients with advanced or recurrent breast cancer

Tetsuhiro Tsuruma, Yuji Iwayama, Tosei Ohmura, Tadashi Katsuramaki, Fumitake Hata, Tomohisa Furuhata, Koji Yamaguchi, Yasutoshi Kimura, Toshihiko Torigoe, Nobuhiko Toyota, Atsuhito Yagihashi, Yoshihik

Journal:

Journal of Translational Medicine

Year:

2008

Language:

english

File:

PDF, 636 KB

english, 2008

92

Proteomic approach with LCMS-IT-TOF identified an increase of Rab33B after transient focal cerebral ischemia in mice

Kana Hyakkoku, Junya Hamanaka, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara

Journal:

Experimental & Translational Stroke Medicine

Year:

2010

Language:

english

File:

PDF, 1.42 MB

english, 2010

93

Role of endoplasmic reticulum stress in light-induced photoreceptor degeneration in mice

Nakanishi, Tomohiro, Shimazawa, Masamitsu, Sugitani, Sou, Kudo, Takashi, Imai, Shunsuke, Inokuchi, Yuta, Tsuruma, Kazuhiro, Hara, Hideaki

Journal:

Journal of Neurochemistry

Year:

2013

Language:

english

File:

PDF, 870 KB

english, 2013

94

A sigma-1 receptor antagonist (NE-100) prevents tunicamycin-induced cell death via GRP78 induction in hippocampal cells

Ono, Yoko, Tanaka, Hirotaka, Tsuruma, Kazuhiro, Shimazawa, Masamitsu, Hara, Hideaki

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 852 KB

english, 2013

95

Thickness mapping of the inner retina by spectral-domain optical coherence tomography in an N-methyl-d-aspartate-induced retinal damage model

Ohno, Yuta, Makita, Shuichi, Shimazawa, Masamitsu, Tsuruma, Kazuhiro, Yasuno, Yoshiaki, Hara, Hideaki

Journal:

Experimental Eye Research

Year:

2013

Language:

english

File:

PDF, 2.62 MB

english, 2013

96

Fasudil, a rho kinase inhibitor, limits motor neuron loss in experimental models of amyotrophic lateral sclerosis

Takata, M, Tanaka, H, Kimura, M, Nagahara, Y, Tanaka, K, Kawasaki, K, Seto, M, Tsuruma, K, Shimazawa, M, Hara, H

Journal:

British Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.67 MB

english, 2013

97

"Shigaku zasshi" Summary of Japanese Scholarship

EGASHIRA HIROSHI, TSURUMA KAZUYUKI, K. Takashima and T. Kleeman

Journal:

Year:

1980-1981

Language:

english

File:

PDF, 1.94 MB

english, 1980-1981

98

The potential neuroprotective effect of human adipose stem cells conditioned medium against light-induced retinal damage

Sugitani, Sou, Tsuruma, Kazuhiro, Ohno, Yuta, Kuse, Yoshiki, Yamauchi, Mika, Egashira, Yusuke, Yoshimura, Shinichi, Shimazawa, Masamitsu, Iwama, Toru, Hara, Hideaki

Journal:

Experimental Eye Research

Year:

2013

Language:

english

File:

PDF, 2.48 MB

english, 2013

99

The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment

Egashira, Yusuke, Suzuki, Yukiya, Azuma, Yukio, Takagi, Toshinori, Mishiro, Keisuke, Sugitani, Sou, Tsuruma, Kazuhiro, Shimazawa, Masamitsu, Yoshimura, Shinichi, Kashimata, Masanori, Iwama, Toru, Hara

Journal:

Journal of Neuroinflammation

Year:

2013

Language:

english

File:

PDF, 782 KB

english, 2013

100

SA4503, a sigma-1 receptor agonist, suppresses motor neuron damage in in vitro and in vivo amyotrophic lateral sclerosis models

Ono, Yoko, Tanaka, Hirotaka, Takata, Masafumi, Nagahara, Yuki, Noda, Yasuhiro, Tsuruma, Kazuhiro, Shimazawa, Masamitsu, Hozumi, Isao, Hara, Hideaki

Journal:

Neuroscience Letters

Year:

2014

Language:

english

File:

PDF, 1016 KB

english, 2014