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1

Comparison of Targeted Next-Generation Sequencing (NGS) and Real-Time PCR in the Detection of EGFR , KRAS, and BRAF Mutations on Formalin-Fixed, Paraffin-Embedded Tumor Material of Non-Small Cell Lung Carcinoma-Superiority of NGS

Tuononen, Katja, Mäki-Nevala, Satu, Sarhadi, Virinder Kaur, Wirtanen, Aino, Rönty, Mikko, Salmenkivi, Kaisa, Andrews, Jenny M., Telaranta-Keerie, Aino I., Hannula, Sari, Lagström, Sonja, Ellonen, Pekk

Journal:

Genes, Chromosomes and Cancer

Year:

2013

Language:

english

File:

PDF, 329 KB

english, 2013

2

CDK4 is a probable target gene in a novel amplicon at 12q13.3–q14.1 in lung cancer

Harriet Wikman, Penny Nymark, Aki Väyrynen, Sonata Jarmalaite, Anne Kallioniemi, Kaisa Salmenkivi, Katri Vainio-Siukola, Kirsti Husgafvel-Pursiainen, Sakari Knuutila, Maija Wolf, Sisko Anttila

Journal:

Genes, Chromosomes and Cancer

Year:

2005

Language:

english

File:

PDF, 317 KB

english, 2005

3

Cutaneous T-cell lymphoma-associated lung cancers show chromosomal aberrations differing from primary lung cancer

Sonja Hahtola, Elke Burghart, Marjut Puputti, Leena Karenko, Wael M. Abdel-Rahman, Liisa Väkevä, Leila Jeskanen, Susanna Virolainen, Jaakko Karvonen, Kaisa Salmenkivi, Vuokko Kinnula, Heikki Joensuu,

Journal:

Genes, Chromosomes and Cancer

Year:

2008

Language:

english

File:

PDF, 635 KB

english, 2008

4

CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant mesothelioma—A miRNA microarray analysis

Mohamed Guled, Leo Lahti, Pamela M. Lindholm, Kaisa Salmenkivi, Izhar Bagwan, Andrew G. Nicholson, Sakari Knuutila

Journal:

Genes, Chromosomes and Cancer

Year:

2009

Language:

english

File:

PDF, 152 KB

english, 2009

5

Integrative analysis of microRNA, mRNA and aCGH data reveals asbestos- and histology-related changes in lung cancer

Penny Nymark, Mohamed Guled, Ioana Borze, Ali Faisal, Leo Lahti, Kaisa Salmenkivi, Eeva Kettunen, Sisko Anttila, Sakari Knuutila

Journal:

Genes, Chromosomes and Cancer

Year:

2011

Language:

english

File:

PDF, 620 KB

english, 2011

6

Cysteine-rich protein 1 is regulated by transforming growth factor-β1 and expressed in lung fibrosis

Päivi M. Järvinen, Marjukka Myllärniemi, Hester Liu, Henna M. Moore, Outi Leppäranta, Kaisa Salmenkivi, Katri Koli, Leena Latonen, Arja M. Band, Marikki Laiho

Journal:

Journal of Cellular Physiology

Year:

2012

Language:

english

File:

PDF, 659 KB

english, 2012

7

VEGF in 105 pheochromocytomas: enhanced expression correlates with malignant outcome

KAISA SALMENKIVI, PÄIVI HEIKKIL, JIANQI LIU, CAJ HAGLUND, JOHANNA AROLA

Journal:

Year:

2003

Language:

english

File:

PDF, 162 KB

english, 2003

8

Hemoglobin α and β are ubiquitous in the human lung, decline in idiopathic pulmonary fibrosis but not in COPD

Nobuhisa Ishikawa, Steffen Ohlmeier, Kaisa Salmenkivi, Marjukka Myllärniemi, Irfan Rahman, Witold Mazur, Vuokko L Kinnula

Journal:

Respiratory Research

Year:

2010

Language:

english

File:

PDF, 2.36 MB

english, 2010

9

Caveolins as tumour markers in lung cancer detected by combined use of cDNA and tissue microarrays

Harriet Wikman, Jouni K Seppänen, Virinder K Sarhadi, Eeva Kettunen, Kaisa Salmenkivi, Eeva Kuosma, Katri Vainio-Siukola, Balint Nagy, Antti Karjalainen, Thanos Sioris, Jarmo Salo, Jaakko Hollmén, Sak

Journal:

The Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 473 KB

english, 2004

10

Role of RNA binding protein HuR in ductal carcinoma in situ of the breast

Mira Heinonen, Annabrita Hemmes, Kaisa Salmenkivi, Kotb Abdelmohsen, Suvi-Tuuli Vilén, Marko Laakso, Marjut Leidenius, Tuula Salo, Sampsa Hautaniemi, Myriam Gorospe, Päivi Heikkilä, Caj Haglund, Ari R

Journal:

The Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 425 KB

english, 2011

11

Proteomic studies on receptor for advanced glycation end product variants in idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease

Steffen Ohlmeier, Witold Mazur, Kaisa Salmenkivi, Marjukka Myllärniemi, Ulrich Bergmann, Vuokko L. Kinnula

Journal:

PROTEOMICS - Clinical Applications

Year:

2010

Language:

english

File:

PDF, 294 KB

english, 2010

12

Malignancy in pheochromocytomas : Review article

KAISA SALMENKIVI, PÄIVI HEIKKILÄ, CAJ HAGLUND, JOHANNA AROLA

Journal:

Year:

2004

Language:

english

File:

PDF, 1.38 MB

english, 2004

13

Elevated matrilysin levels in bronchoalveolar lavage fluid do not distinguish idiopathic pulmonary fibrosis from other interstitial lung diseases

KIRSI VUORINEN, MARJUKKA MYLLÄRNIEMI, LAURI LAMMI, PÄIVI PIIRILÄ, PAULA RYTILÄ, KAISA SALMENKIVI, VUOKKO L. KINNULA

Journal:

Year:

2007

Language:

english

File:

PDF, 201 KB

english, 2007

14

Cell-specific elevation of NRF2 and sulfiredoxin-1 as markers of oxidative stress in the lungs of idiopathic pulmonary fibrosis and non-specific interstitial pneumonia

WITOLD MAZUR, PAMELA LINDHOLM, KIRSI VUORINEN, MARJUKKA MYLLÄRNIEMI, KAISA SALMENKIVI, VUOKKO L. KINNULA

Journal:

Year:

2010

Language:

english

File:

PDF, 428 KB

english, 2010

15

Regulation of TGF-β storage and activation in the human idiopathic pulmonary fibrosis lung

Outi Leppäranta, Carla Sens, Kaisa Salmenkivi, Vuokko L. Kinnula, Jorma Keski-Oja, Marjukka Myllärniemi, Katri Koli

Journal:

Cell and Tissue Research

Year:

2012

Language:

english

File:

PDF, 776 KB

english, 2012

16

Expression of snail, twist, and Zeb1 in malignant mesothelioma

Heta Merikallio, Paavo Paakko, Kaisa Salmenkivi, Vuokko Kinnula, Teihu Harju, Ylermi Soini

Journal:

Year:

2012

Language:

english

File:

PDF, 571 KB

english, 2012

17

Variability in the precursor proteins of collagen I and III in different stages of COPD

Terttu Harju, Vuokko L Kinnula, Paavo Pääkkö, Kaisa Salmenkivi, Juha Risteli, Riitta Kaarteenaho

Journal:

Respiratory Research

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

18

Frequent loss of heterozygosity at 6q in pheochromocytoma

Sebsebe Lemeta, Kaisa Salmenkivi, Lea Pylkkänen, Markku Sainio, Sirkku T. Saarikoski, Johanna Arola, Päivi Heikkilä, Caj Haglund, Kirsti Husgafvel-Pursiainen, Tom Böhling

Journal:

Human Pathology

Year:

2006

Language:

english

File:

PDF, 273 KB

english, 2006

19

Latent TGF-β binding proteins (LTBPs) 1 and 3 differentially regulate transforming growth factor-β activity in malignant mesothelioma

Piia Vehviläinen, Katri Koli, Marjukka Myllärniemi, Pamela Lindholm, Ylermi Soini, Kaisa Salmenkivi, Vuokko L. Kinnula, Jorma Keski-Oja

Journal:

Human Pathology

Year:

2011

Language:

english

File:

PDF, 880 KB

english, 2011

20

ELMOD2 Is a Candidate Gene for Familial Idiopathic Pulmonary Fibrosis

Ulla Hodgson, Ville Pulkkinen, Morag Dixon, Myriam Peyrard-Janvid, Marko Rehn, Päivi Lahermo, Vesa Ollikainen, Kaisa Salmenkivi, Vuokko Kinnula, Juha Kere, Pentti Tukiainen, Tarja Laitinen

Journal:

The American Journal of Human Genetics

Year:

2006

Language:

english

File:

PDF, 752 KB

english, 2006

21

Bone Morphogenetic Protein-4 Inhibitor Gremlin Is Overexpressed in Idiopathic Pulmonary Fibrosis

Katri Koli, Marjukka Myllärniemi, Kirsi Vuorinen, Kaisa Salmenkivi, Merja J. Ryynänen, Vuokko L. Kinnula, Jorma Keski-Oja

Journal:

The American Journal of Pathology

Year:

2006

Language:

english

File:

PDF, 1.39 MB

english, 2006

22

Copy number gains on 5p15, 6p11-q11, 7p12, and 8q24 are rare in sputum cells of individuals at high risk of lung cancer

Kettunen, Eeva, Salmenkivi, Kaisa, Vuopala, Katri, Toljamo, Tuula, Kuosma, Eeva, Norppa, Hannu, Knuutila, Sakari, Kaleva, Simo, Huuskonen, Matti S., Anttila, Sisko

Journal:

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

23

Modulation of glutaredoxin in the lung and sputum of cigarette smokers and chronic obstructive pulmonary disease

Mirva J Peltoniemi, Paula H Rytilä, Terttu H Harju, Ylermi M Soini, Kaisa M Salmenkivi, Lloyd W Ruddock, Vuokko L Kinnula

Journal:

Respiratory Research

Year:

2006

Language:

english

File:

PDF, 1.57 MB

english, 2006

24

Glutathione S-transferase omega in the lung and sputum supernatants of COPD patients

Terttu H Harju, Mirva J Peltoniemi, Paula H Rytilä, Ylermi Soini, Kaisa M Salmenkivi, Philip G Board, Lloyd W Ruddock, Vuokko L Kinnula

Journal:

Respiratory Research

Year:

2007

Language:

english

File:

PDF, 1.27 MB

english, 2007

25

Proteomics of Human Lung Tissue Identifies Surfactant Protein A as a Marker of Chronic Obstructive Pulmonary Disease

Ohlmeier, Steffen, Vuolanto, Minna, Toljamo, Tuula, Vuopala, Katri, Salmenkivi, Kaisa, Myllärniemi, Marjukka, Kinnula, Vuokko L.

Journal:

Journal of Proteome Research

Year:

2008

Language:

english

File:

PDF, 6.85 MB

english, 2008

26

A novel screening method detects herpesviral DNA in the idiopathic pulmonary fibrosis lung

Pulkkinen, Ville, Salmenkivi, Kaisa, Kinnula, Vuokko L., Sutinen, Eva, Halme, Maija, Hodgson, Ulla, Lehto, Juho, Jääskeläinen, Anne, Piiparinen, Heli, Kere, Juha, Lautenschlager, Irmeli, Lappalainen,

Journal:

Annals of Medicine

Year:

2012

Language:

english

File:

PDF, 330 KB

english, 2012

27

Carbonic anhydrase IX in malignant pleural mesotheliomas: A potential target for anti-cancer therapy

Kivelä, Antti J., Knuuttila, Aija, Räsänen, Jari, Sihvo, Eero, Salmenkivi, Kaisa, Saarnio, Juha, Pastorekova, Silvia, Pastorek, Jaromir, Waheed, Abdul, Sly, William S., Salo, Jarmo A., Parkkila, Seppo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.48 MB

english, 2013

28

Accumulation of genomic alterations in 2p16, 9q33.1 and 19p13 in lung tumours of asbestos-exposed patients

Nymark, Penny, Aavikko, Mervi, Mäkilä, Jussi, Ruosaari, Salla, Hienonen-Kempas, Tuija, Wikman, Harriet, Salmenkivi, Kaisa, Pirinen, Risto, Karjalainen, Antti, Vanhala, Esa, Kuosma, Eeva, Anttila, Sisk

Journal:

Molecular Oncology

Year:

2013

Language:

english

File:

PDF, 437 KB

english, 2013

29

Predicting invasion in patients with DCIS in the preoperative percutaneous biopsy

Leikola, Junnu, Heikkilä, Päivi, Pamilo, Martti, Salmenkivi, Kaisa, Von Smitten, Karl, Leidenius, Marjut

Journal:

Acta Oncologica

Year:

2007

Language:

english

File:

PDF, 58 KB

english, 2007

30

Targeted Resequencing Reveals ALK Fusions in Non-Small Cell Lung Carcinomas Detected by FISH, Immunohistochemistry, and Real-Time RT-PCR: A Comparison of Four Methods

Tuononen, Katja, Sarhadi, Virinder Kaur, Wirtanen, Aino, Rönty, Mikko, Salmenkivi, Kaisa, Knuuttila, Aija, Remes, Satu, Telaranta-Keerie, Aino I., Bloor, Stuart, Ellonen, Pekka, Knuutila, Sakari

Journal:

BioMed Research International

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013

31

Oxidative stress in non-small cell lung cancer: Role of nicotinamide adenine dinucleotide phosphate oxidase and glutathione

Ilonen, Ilkka K., Räsänen, Jari V., Sihvo, Eero I., Knuuttila, Aija, Salmenkivi, Kaisa M., Ahotupa, Markku O., Kinnula, Vuokko L., Salo, Jarmo A.

Journal:

Acta Oncologica

Year:

2009

Language:

english

File:

PDF, 83 KB

english, 2009

32

Reduced Phosphorylation of the TGF-β Signal Transducer Smad2 in Emphysematous Human Lung

Leppäranta, Outi, Myllärniemi, Marjukka, Salmenkivi, Kaisa, Kinnula, Vuokko L., Keski-Oja, Jorma, Koli, Katri

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Year:

2009

Language:

english

File:

PDF, 317 KB

english, 2009

33

The expression of p53, bcl-2, bax, fas and fasL in the primary tumour and lymph node metastases of breast cancer

Sjöström-mattson, Johanna, Von Boguslawski, Kristina, Bengtsson, Nils-Olof, Mjaaland, Ingvil, Salmenkivi, Kaisa, Blomqvist, Carl

Journal:

Acta Oncologica

Year:

2009

Language:

english

File:

PDF, 111 KB

english, 2009

34

Gremlin-mediated Decrease in Bone Morphogenetic Protein Signaling Promotes Pulmonary Fibrosis

Myllärniemi, Marjukka, Lindholm, Pamela, Ryynänen, Merja J., Kliment, Corrine R., Salmenkivi, Kaisa, Keski-Oja, Jorma, Kinnula, Vuokko L., Oury, Tim D., Koli, Katri

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2008

Language:

english

File:

PDF, 824 KB

english, 2008

35

Transcription Factor GATA-6 Is Expressed in Quiescent Myofibroblasts in Idiopathic Pulmonary Fibrosis

Leppäranta, Outi, Pulkkinen, Ville, Koli, Katri, Vähätalo, Riika, Salmenkivi, Kaisa, Kinnula, Vuokko L., Heikinheimo, Markku, Myllärniemi, Marjukka

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 863 KB

english, 2010

36

Increased Expression of Cyclooxygenase-2 in Malignant Pheochromocytomas

Salmenkivi, Kaisa, Haglund, Caj, Ristimäki, Ari, Arola, Johanna, Heikkilä, Päivi

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2001

Language:

english

File:

PDF, 298 KB

english, 2001

37

Up-Regulation of Trypsin and Mesenchymal MMP-8 During Development of Hyperoxic Lung Injury in the Rat

Cederqvist, Katariina, Janer, Joakim, Tervahartiala, Taina, Sorsa, Timo, Haglund, Caj, Salmenkivi, Kaisa, Stenman, Ulf-Håkan, Andersson, Sture

Journal:

Pediatric Research

Year:

2006

Language:

english

File:

PDF, 411 KB

english, 2006

38

Inhibin/Activin βB-Subunit Expression in Pheochromocytomas Favors Benign Diagnosis 1

Salmenkivi, Kaisa, Arola, Johanna, Voutilainen, Raimo, Ilvesmäki, Vesa, Haglund, Caj, Kahri, Arvi I., Heikkilä, Päivi, Liu, Jianqi

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2001

Language:

english

File:

PDF, 477 KB

english, 2001

39

Increased Expression of Tenascin in Pheochromocytomas Correlates With Malignancy

Salmenkivi, Kaisa, Haglund, Caj, Arola, Johanna, Heikkilä, Päivi

Journal:

American Journal of Surgical Pathology

Year:

2001

Language:

english

File:

PDF, 2.66 MB

english, 2001

40

Long-term outcome and its predictors in giant cell myocarditis

Ekström, Kaj, Lehtonen, Jukka, Kandolin, Riina, Räisänen-Sokolowski, Anne, Salmenkivi, Kaisa, Kupari, Markku

Journal:

European Journal of Heart Failure

Year:

2016

Language:

english

File:

PDF, 402 KB

english, 2016

41

HuR in pheochromocytomas and paragangliomas - overexpression in verified malignant tumors

Leijon, Helena, Salmenkivi, Kaisa, Heiskanen, Ilkka, Hagström, Jaana, Louhimo, Johanna, Heikkilä, Päivi, Ristimäki, Ari, Paavonen, Timo, Metso, Saara, Mäenpää, Hanna, Haglund, Caj, Arola, Johanna

Journal:

Year:

2016

Language:

english

File:

PDF, 371 KB

english, 2016

42

Incidence, Risk Factors, and Outcome of Life-Threatening Ventricular Arrhythmias in Giant Cell Myocarditis

Ekström, Kaj, Lehtonen, Jukka, Kandolin, Riina, Räisänen-Sokolowski, Anne, Salmenkivi, Kaisa, Kupari, Markku

Journal:

Circulation Arrhythmia and Electrophysiology

Year:

2016

Language:

english

File:

PDF, 685 KB

english, 2016

43

Cell of Origin Links Histotype Spectrum to Immune Microenvironment Diversity in Non-small-Cell Lung Cancer Driven by Mutant Kras and Loss of Lkb1

Nagaraj, Ashwini S., Lahtela, Jenni, Hemmes, Annabrita, Pellinen, Teijo, Blom, Sami, Devlin, Jennifer R., Salmenkivi, Kaisa, Kallioniemi, Olli, Mäyränpää, Mikko I., Närhi, Katja, Verschuren, Emmy W.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.81 MB

english, 2017

44

Asbestos-associated genome-wide DNA methylation changes in lung cancer

Kettunen, Eeva, Hernandez-Vargas, Hector, Cros, Marie-Pierre, Durand, Geoffroy, Le Calvez-Kelm, Florence, Stuopelyte, Kristina, Jarmalaite, Sonata, Salmenkivi, Kaisa, Anttila, Sisko, Wolff, Henrik, He

Journal:

International Journal of Cancer

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

45

Analysis of the Histologic Features Associated With Interobserver Variation in Idiopathic Pulmonary Fibrosis

Mäkelä, Kati, Hodgson, Ulla, Piilonen, Anneli, Kelloniemi, Katariina, Bloigu, Risto, Sutinen, Eva, Salmenkivi, Kaisa, Rönty, Mikko, Lappi-Blanco, Elisa, Myllärniemi, Marjukka, Kaarteenaho, Riitta

Journal:

American Journal of Surgical Pathology

Year:

2018

Language:

english

File:

PDF, 196 KB

english, 2018

46

Spatial Aspects of Oncogenic Signaling Determine Response to Combination Therapy in Slice Explants from Kras -driven Lung Tumors

Närhi, Katja, Nagaraj, Ashwini S., Parri, Elina, Turkki, Riku, van Duijn, Petra W., Hemmes, Annabrita, Lahtela, Jenni, Uotinen, Virva, Mäyränpää, Mikko I., Salmenkivi, Kaisa, Räsänen, Jari, Linder, Ni

Journal:

The Journal of Pathology

Year:

2018

Language:

english

File:

PDF, 1.98 MB

english, 2018

47

Clinicopathological indicators of survival among patients with pulmonary carcinoid tumor

Vesterinen, Tiina, Mononen, Sanna, Salmenkivi, Kaisa, Mustonen, Harri, Ilonen, Ilkka, Knuuttila, Aija, Haglund, Caj, Arola, Johanna

Journal:

Acta Oncologica

Year:

2018

Language:

english

File:

PDF, 1.93 MB

english, 2018

48

CDKN2A copy number and p16 expression in malignant pleural mesothelioma in relation to asbestos exposure

Kettunen, Eeva, Savukoski, Sauli, Salmenkivi, Kaisa, Böhling, Tom, Vanhala, Esa, Kuosma, Eeva, Anttila, Sisko, Wolff, Henrik

Journal:

Year:

2019

Language:

english

File:

PDF, 888 KB

english, 2019

49

CDKN2A copy number and p16 expression in malignant pleural mesothelioma in relation to asbestos exposure

Kettunen, Eeva, Savukoski, Sauli, Salmenkivi, Kaisa, Böhling, Tom, Vanhala, Esa, Kuosma, Eeva, Anttila, Sisko, Wolff, Henrik

Journal:

Year:

2019

File:

PDF, 888 KB

2019

50

Performance of Finnish biobanks in nationwide pulmonary carcinoid tumour research

Vesterinen, Tiina, Salmenkivi, Kaisa, Mustonen, Harri, Kuopio, Teijo, Lappi-Blanco, Elisa, Paavonen, Timo, Vainio, Paula, Knuuttila, Aija, Carpén, Olli, Haglund, Caj, Arola, Johanna

Journal:

Virchows Archiv

Year:

2019

Language:

english

File:

PDF, 933 KB

english, 2019

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