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51

PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells

Yusuke Tanaka, Fumiko Sekiguchi, Hao Hong, Atsufumi Kawabata

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 524 KB

english, 2008

52

Gastrointestinal functions of proteinase-activated receptors

Atsufumi Kawabata

Journal:

Year:

2003

Language:

english

File:

PDF, 202 KB

english, 2003

53

Effect of a potent iNOS inhibitor (ONO-1714) on acetaminophen-induced hepatotoxicity in the rat

Yoshihisa Kamanaka, Atsufumi Kawabata, Hidekazu Matsuya, Chiyomi Taga, Fumiko Sekiguchi, Naoyuki Kawao

Journal:

Year:

2003

Language:

english

File:

PDF, 282 KB

english, 2003

54

Receptor-activating peptides for PAR-1 and PAR-2 relax rat gastric artery via multiple mechanisms

Atsufumi Kawabata, Yumiko Nakaya, Tsuyoshi Ishiki, Satoko Kubo, Ryotaro Kuroda, Fumiko Sekiguchi, Naoyuki Kawao, Hiroyuki Nishikawa, Kenzo Kawai

Journal:

Year:

2004

Language:

english

File:

PDF, 339 KB

english, 2004

55

Mechanisms for modulation of mouse gastrointestinal motility by proteinase-activated receptor (PAR)-1 and -2 in vitro

Fumiko Sekiguchi, Naomi Hasegawa, Keiko Inoshita, Daiki Yonezawa, Naoki Inoi, Toru Kanke, Naohiro Saito, Atsufumi Kawabata

Journal:

Year:

2006

Language:

english

File:

PDF, 438 KB

english, 2006

56

The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents

Hiroyasu Ishikura, Sachiyo Nishimura, Maho Matsunami, Toshifumi Tsujiuchi, Tsuyoshi Ishiki, Fumiko Sekiguchi, Mitsuhide Naruse, Toshio Nakatani, Yoshihisa Kamanaka, Atsufumi Kawabata

Journal:

Year:

2007

Language:

english

File:

PDF, 821 KB

english, 2007

57

The proteinase/proteinase-activated receptor-2/transient receptor potential vanilloid-1 cascade impacts pancreatic pain in mice

Sachiyo Nishimura, Hiroyasu Ishikura, Maho Matsunami, Yui Shinozaki, Fumiko Sekiguchi, Mitsuhide Naruse, Taisuke Kitamura, Ryukichi Akashi, Kenji Matsumura, Atsufumi Kawabata

Journal:

Year:

2010

Language:

english

File:

PDF, 1.60 MB

english, 2010

58

The potent inducible nitric oxide synthase inhibitor ONO-1714 inhibits neuronal NOS and exerts antinociception in rats

Fumiko Sekiguchi, Yoko Mita, Yoshihisa Kamanaka, Naoyuki Kawao, Hidekazu Matsuya, Chiyomi Taga, Atsufumi Kawabata

Journal:

Neuroscience Letters

Year:

2004

Language:

english

File:

PDF, 118 KB

english, 2004

59

Antiallodynic effect of etidronate, a bisphosphonate, in rats with adjuvant-induced arthritis: Involvement of ATP-sensitive K+ channels

Atsufumi Kawabata, Naoyuki Kawao, Yoshimi Hironaka, Tsuyoshi Ishiki, Maho Matsunami, Fumiko Sekiguchi

Journal:

Neuropharmacology

Year:

2006

Language:

english

File:

PDF, 557 KB

english, 2006

60

Hydrogen sulfide as a novel nociceptive messenger

Atsufumi Kawabata, Tsuyoshi Ishiki, Keita Nagasawa, Shigeru Yoshida, Yumi Maeda, Tomoko Takahashi, Fumiko Sekiguchi, Tetsuyuki Wada, Seiji Ichida, Hiroyuki Nishikawa

Journal:

Year:

2007

Language:

english

File:

PDF, 634 KB

english, 2007

61

Roles for H2S in pain processing: Response to Cunha and Verri

Atsufumi Kawabata

Journal:

Year:

2007

Language:

english

File:

PDF, 62 KB

english, 2007

62

Hyperalgesia induced by spinal and peripheral hydrogen sulfide: Evidence for involvement of Cav3.2 T-type calcium channels

Yumi Maeda, Yuka Aoki, Fumiko Sekiguchi, Maho Matsunami, Tomoko Takahashi, Hiroyuki Nishikawa, Atsufumi Kawabata

Journal:

Year:

2009

Language:

english

File:

PDF, 550 KB

english, 2009

63

The PAR-1-activating peptide facilitates pepsinogen secretion in rats

Naoyuki Kawao, Kaori Hiramatsu, Naoki Inoi, Ryotaro Kuroda, Hiroyuki Nishikawa, Fumiko Sekiguchi, Atsufumi Kawabata

Journal:

Year:

2003

Language:

english

File:

PDF, 68 KB

english, 2003

64

Signal transduction for formation/release of interleukin-8 caused by a PAR2-activating peptide in human lung epithelial cells

Kazumi Moriyuki, Mami Nagataki, Fumiko Sekiguchi, Hiroyuki Nishikawa, Atsufumi Kawabata

Journal:

Regulatory Peptides

Year:

2008

Language:

english

File:

PDF, 590 KB

english, 2008

65

Somatosensory cortex stimulation-evoked analgesia in rats: Potentiation by no synthase inhibition

Ryotaro Kuroda, Atsufumi Kawabata, Naoyuki Kawao, Wakana Umeda, Motohide Takemura, Yoshio Shigenaga

Journal:

Year:

2000

Language:

english

File:

PDF, 454 KB

english, 2000

66

Characterization of the protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle

Atsufumi Kawabata, Ryotaro Kuroda, Naoko Kuroki, Hiroyuki Nishikawa, Kenzo Kawai, Hiromasa Araki

Journal:

Year:

2000

Language:

english

File:

PDF, 218 KB

english, 2000

67

Protease-activated receptor-2 (PAR-2) in the pancreas and parotid gland: Immunolocalization and involvement of nitric oxide in the evoked amylase secretion

Atsufumi Kawabata, Ryotaro Kuroda, Minoru Nishida, Nanae Nagata, Yuriko Sakaguchi, Naoyuki Kawao, Hiroyuki Nishikawa, Naoki Arizono, Kenzo Kawai

Journal:

Year:

2002

Language:

english

File:

PDF, 249 KB

english, 2002

68

Cross tolerance to environmental stress and endotoxin

Atsufumi Kawabata, Taeko Hata, Ryotaro Kuroda

Journal:

Year:

1998

Language:

english

File:

PDF, 470 KB

english, 1998

69

Ex Vivo Evidence That the Phosphodiesterase Inhibitor IBMX Attenuates the Up-Regulation of PAR-2 in the Endotoxemic Rat Aorta

Atsufumi Kawabata, Ryotaro Kuroda, Yumiko Nakaya, Naoyuki Kawao, Hiroyuki Nishikawa

Journal:

Thrombosis Research

Year:

2001

Language:

english

File:

PDF, 129 KB

english, 2001

70

The PAR-1-activating peptide attenuates carrageenan-induced hyperalgesia in rats

Atsufumi Kawabata, Naoyuki Kawao, Ryotaro Kuroda, Atsuko Tanaka, Chiho Shimada

Journal:

Year:

2002

Language:

english

File:

PDF, 79 KB

english, 2002

71

Role of N-methyl-d-aspartate receptors and the nitric oxide pathway in nociception/hyperalgesia elicited by protease-activated receptor-2 activation in mice and rats

Atsufumi Kawabata, Naoyuki Kawao, Hideki Itoh, Chiho Shimada, Kaori Takebe, Ryotaro Kuroda, Takashi Masuko, Kazuo Kataoka, Shinji Ogawa

Journal:

Neuroscience Letters

Year:

2002

Language:

english

File:

PDF, 135 KB

english, 2002

72

Lipopolysaccharide-induced platinum accumulation in the cerebral cortex after cisplatin administration in mice: Involvement of free radicals

Takeshi Minami, Jiro Okazaki, Atsufumi Kawabata, Hideko Kawaki, Yuko Okazaki

Journal:

Environmental Toxicology and Pharmacology

Year:

1996

Language:

english

File:

PDF, 543 KB

english, 1996

73

Roles of nitric oxide and prostaglandins in the increased permeability of the blood-brain barrier caused by lipopolysaccharide

Takeshi Minami, Jiro Okazaki, Atsufumi Kawabata, Hideko Kawaki, Yuko Okazaki, Yoshiyuki Tohno

Journal:

Environmental Toxicology and Pharmacology

Year:

1998

Language:

english

File:

PDF, 258 KB

english, 1998

74

l-Leucyl-l-arginine, naltrindole and d-arginine block antinociception elicited by l-arginine in mice with carrageenin-induced hyperalgesia

Atsufumi Kawabata, Yumiko Nishimura, Hiroshi Takagi

Journal:

British Journal of Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.07 MB

english, 1992

75

l-Arginine exerts a dual role in nociceptive processing in the brain: involvement of the kyotorphin-Met-enkephalin pathway and NO-cyclic GMP pathway

Atsufumi Kawabata, Nahoko Umeda, Hiroshi Takagi

Journal:

British Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 1.10 MB

english, 1993

76

Effect of topical administration of l-arginine on formalin-induced nociception in the mouse: a dual role of peripherally formed NO in pain modulation

Atsufumi Kawabata, Sachiko Manabe, Yuki Manabe, Hiroshi Takagi

Journal:

British Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 750 KB

english, 1994

77

Comparison of antinociception induced by supraspinally administered l-arginine and kyotorphin

Atsufumi Kawabata, Sachiko Manabe, Hiroshi Takagi

Journal:

British Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.02 MB

english, 1994

78

The noradrenaline precursor l-threo-3,4-dihydroxyphenylserine exhibits antinociceptive activity via central α-adrenoceptors in the mouse

Atsufumi Kawabata, Kazuyo Kasamatsu, Nahoko Umeda, Hiroshi Takagi

Journal:

British Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.09 MB

english, 1994

79

Involvement of the endogenous hydrogen sulfide/Cav3.2 T-type Ca2+ channel pathway in cystitis-related bladder pain in mice

Maho Matsunami, Takahiro Miki, Kanae Nishiura, Yuko Hayashi, Yasumasa Okawa, Hiroyuki Nishikawa, Fumiko Sekiguchi, Lisa Kubo, Tomoka Ozaki, Toshifumi Tsujiuchi, Atsufumi Kawabata

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.06 MB

english, 2012

80

Colonic hyperalgesia triggered by proteinase-activated receptor-2 in mice: Involvement of endogenous bradykinin

Atsufumi Kawabata, Naoyuki Kawao, Tomoko Kitano, Maho Matsunami, Reiko Satoh, Tsuyoshi Ishiki, Takashi Masuko, Toru Kanke, Naohiro Saito

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 442 KB

english, 2006

81

Characterization of platelet hypofunctions in rats under SART stress (repeated cold stress)

Atsufumi Kawabata, Taeko Hata

Journal:

Thrombosis Research

Year:

1993

Language:

english

File:

PDF, 770 KB

english, 1993

82

A protective role of protease-activated receptor 1 in rat gastric mucosa

Atsufumi Kawabata, Hiroyuki Nishikawa, Hitomi Saitoh, Yumiko Nakaya, Kaori Hiramatsu, Satoko Kubo, Minoru Nishida, Naoyuki Kawao, Ryotaro Kuroda, Fumiko Sekiguchi, Mitsuhiro Kinoshita, Kazuaki Kakehi,

Journal:

Gastroenterology

Year:

2004

Language:

english

File:

PDF, 597 KB

english, 2004

83

AKAP-dependent sensitization of Ca v 3.2 channels via the EP 4 receptor/cAMP pathway mediates PGE 2 -induced mechanical hyperalgesia

Sekiguchi, Fumiko, Aoki, Yuka, Nakagawa, Maiko, Kanaoka, Daiki, Nishimoto, Yuta, Tsubota-Matsunami, Maho, Yamanaka, Rumi, Yoshida, Shigeru, Kawabata, Atsufumi

Journal:

British Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.84 MB

english, 2013

84

Bladder pain relief by HMGB1 neutralization and soluble thrombomodulin in mice with cyclophosphamide-induced cystitis

Tanaka, Junichi, Yamaguchi, Kaoru, Ishikura, Hiroyasu, Tsubota, Maho, Sekiguchi, Fumiko, Seki, Yukari, Tsujiuchi, Toshifumi, Murai, Akira, Umemura, Takehiro, Kawabata, Atsufumi

Journal:

Neuropharmacology

Year:

2014

Language:

english

File:

PDF, 1004 KB

english, 2014

85

Recombinant human soluble thrombomodulin prevents peripheral HMGB1-dependent hyperalgesia in rats

Tanaka, Junichi, Seki, Yukari, Ishikura, Hiroyasu, Tsubota, Maho, Sekiguchi, Fumiko, Yamaguchi, Kaoru, Murai, Akira, Umemura, Takehiro, Kawabata, Atsufumi

Journal:

British Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

86

Endogenous and exogenous hydrogen sulfide facilitates T-type calcium channel currents in Cav3.2-expressing HEK293 cells

Sekiguchi, Fumiko, Miyamoto, Yosuke, Kanaoka, Daiki, Ide, Hiroki, Yoshida, Shigeru, Ohkubo, Tsuyako, Kawabata, Atsufumi

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 553 KB

english, 2014

87

P43 Ascorbic acid deficiency augments hyperalgesia induced by hydrogen sulfide in mice

Tsubota, Maho, Uebo, Kenta, Miki, Koki, Sekiguchi, Fumiko, Kondo, Yoshitaka, Takahashi, Keita, Masutomi, Hirofumi, Ishigami, Akihito, Kawabata, Atsufumi

Journal:

Year:

2014

Language:

english

File:

PDF, 41 KB

english, 2014

88

Specific Distribution of Sialic Acids in Animal Tissues As Examined by LC−ESI-MS after Derivatization with 1,2-Diamino-4,5-Methylenedioxybenzene

Morimoto, Nao, Nakano, Miyako, Kinoshita, Mitsuhiro, Kawabata, Atsufumi, Morita, Masanori, Oda, Yasuo, Kuroda, Ryotaro, Kakehi, Kazuaki

Journal:

Analytical Chemistry

Year:

2001

Language:

english

File:

PDF, 115 KB

english, 2001

89

Ouabain exerts cytoprotection by diminishing the intracellular K + concentration increase caused by distinct stimuli in human leukemic cells

Takechi, Masayuki, Wada, Tetsuyuki, Yagi, Hideki, Masuko, Takashi, Kawabata, Atsufumi

Journal:

Journal of Pharmacy and Pharmacology

Year:

2015

Language:

english

File:

PDF, 693 KB

english, 2015

90

Polaprezinc attenuates cyclophosphamide-induced cystitis and related bladder pain in mice

Murakami-Nakayama, Masahiro, Tsubota, Maho, Hiruma, Saki, Sekiguchi, Fumiko, Matsuyama, Kenji, Kimura, Takeshi, Moriyama, Masahiro, Kawabata, Atsufumi

Journal:

Journal of Pharmacological Sciences

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

91

PAR-2: structure, function and relevance to human diseases of the gastric mucosa

Kawabata, Atsufumi

Journal:

Expert Reviews in Molecular Medicine

Year:

2002

Language:

english

File:

PDF, 514 KB

english, 2002

92

Hydrogen sulfide and neuronal differentiation: Focus on Ca2+ channels

Fukami, Kazuki, Kawabata, Atsufumi

Journal:

Year:

2015

Language:

english

File:

PDF, 706 KB

english, 2015

93

Mechanisms for proteinase-activated receptor 1-triggered prostaglandin E2 generation in mouse osteoblastic MC3T3-E1 cells

Maeda, Yuma, Sekiguchi, Fumiko, Yamanaka, Rumi, Sugimoto, Ryo, Yamasoba, Daichi, Tomita, Shiori, Nishikawa, Hiroyuki, Kawabata, Atsufumi

Journal:

Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 2.57 MB

english, 2015

94

Functional upregulation of the H2S/Cav3.2 channel pathway accelerates secretory function in neuroendocrine-differentiated human prostate cancer cells

Fukami, Kazuki, Sekiguchi, Fumiko, Yasukawa, Miku, Asano, Erina, Kasamatsu, Ryuji, Ueda, Mai, Yoshida, Shigeru, Kawabata, Atsufumi

Journal:

Biochemical Pharmacology

Year:

2015

Language:

english

File:

PDF, 2.33 MB

english, 2015

95

Peripheral HMGB1-induced hyperalgesia in mice: Redox state-dependent distinct roles of RAGE and TLR4

Yamasoba, Daichi, Tsubota, Maho, Domoto, Risa, Sekiguchi, Fumiko, Nishikawa, Hiroyuki, Liu, Keyue, Nishibori, Masahiro, Ishikura, Hiroyasu, Yamamoto, Tetsushi, Taga, Atsushi, Kawabata, Atsufumi

Journal:

Journal of Pharmacological Sciences

Year:

2016

Language:

english

File:

PDF, 1.21 MB

english, 2016

96

Peripheral PAR-2 triggers thermal hyperalgesia and nociceptive responses in rats

Kawabata, Atsufumi, Kawao, Naoyuki, Kuroda, Ryotaro, Tanaka, Atsuko, Itoh, Hideki, Nishikawa, Hiroyuki

Journal:

Year:

2001

Language:

english

File:

PDF, 189 KB

english, 2001

97

Specific expression of spinal Fos after PAR-2 stimulation in mast cell-depleted rats

Kawabata, Atsufumi, Kawao, Naoyuki, Kuroda, Ryotaro, Itoh, Hideki, Nishikawa, Hiroyuki

Journal:

Year:

2002

Language:

english

File:

PDF, 428 KB

english, 2002

98

The prostaglandin E2/EP4 receptor/cyclic AMP/T-type Ca2+ channel pathway mediates neuritogenesis in sensory neuron-like ND7/23 cells

Mitani, Kenji, Sekiguchi, Fumiko, Maeda, Takashi, Tanaka, Yukari, Yoshida, Shigeru, Kawabata, Atsufumi

Journal:

Journal of Pharmacological Sciences

Year:

2016

Language:

english

File:

PDF, 1.06 MB

english, 2016

99

Selective sensitization of C-fiber nociceptors by hydrogen sulfide

Aoki, Yuka, Tsubota, Maho, Nishimoto, Yuta, Maeda, Yumi, Sekiguchi, Fumiko, Kawabata, Atsufumi

Journal:

Journal of Pharmacological Sciences

Year:

2016

Language:

english

File:

PDF, 1.29 MB

english, 2016

100

Roles of Ca v 3.2 and TRPA1 channels targeted by hydrogen sulfide in pancreatic nociceptive processing in mice with or without acute pancreatitis

Terada, Yuka, Fujimura, Mayuko, Nishimura, Sachiyo, Tsubota, Maho, Sekiguchi, Fumiko, Kawabata, Atsufumi

Journal:

Journal of Neuroscience Research

Year:

2015

Language:

english

File:

PDF, 630 KB

english, 2015