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1

Selective expression of Gi/o-coupled ATP receptor P2Y12 in microglia in rat brain

Yo Sasaki, Masato Hoshi, Chihiro Akazawa, Yasuko Nakamura, Hayami Tsuzuki, Kazuhide Inoue, Shinichi Kohsaka

Journal:

Year:

2003

Language:

english

File:

PDF, 464 KB

english, 2003

2

Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity

Keiko Ohsawa, Yoshinori Imai, Yo Sasaki, Shinichi Kohsaka

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 530 KB

english, 2004

3

Microglia-specific localisation of a novel calcium binding protein, Iba1

Daisuke Ito, Yoshinori Imai, Keiko Ohsawa, Kazuyuki Nakajima, Yasuo Fukuuchi, Shinichi Kohsaka

Journal:

Molecular Brain Research

Year:

1998

Language:

english

File:

PDF, 2.09 MB

english, 1998

4

Upregulated Expression of Iba1 Molecules in the Central Nervous System of Mice in Response to Neurovirulent Influenza A Virus Infection

Mori, Isamu, Imai, Yoshinori, Kohsaka, Shinichi, Kimura, Yoshinobu

Journal:

Microbiology and Immunology

Year:

2000

Language:

english

File:

PDF, 13.52 MB

english, 2000

5

Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K + Channel THIK-1

Madry, Christian, Kyrargyri, Vasiliki, Arancibia-Cárcamo, I. Lorena, Jolivet, Renaud, Kohsaka, Shinichi, Bryan, Robert M., Attwell, David

Journal:

Year:

2017

Language:

english

File:

PDF, 5.77 MB

english, 2017

6

Lipopolysaccharide enhances synthesis of brain-derived neurotrophic factor in cultured rat microglia

Tetsuya Miwa, Shoei Furukawa, Kazuyuki Nakajima, Yoshiko Furukawa, Shinichi Kohsaka

Journal:

Journal of Neuroscience Research

Year:

1997

Language:

english

File:

PDF, 105 KB

english, 1997

7

Involvement of amyloid precursor protein in functional synapse formation in cultured hippocampal neurons

Takako Morimoto, Ikuroh Ohsawa, Chizuko Takamura, Mariko Ishiguro, Shinichi Kohsaka

Journal:

Journal of Neuroscience Research

Year:

1998

Language:

english

File:

PDF, 388 KB

english, 1998

8

Generation and characterization of a microglial cell line, MG5, derived from a p53-deficient mouse

Keiko Ohsawa, Yoshinori Imai, Kazuyuki Nakajima, Shinichi Kohsaka

Journal:

Year:

1997

Language:

english

File:

PDF, 947 KB

english, 1997

9

Neurotrophins regulate the function of cultured microglia

Kazuyuki Nakajima, Yoshiaki Kikuchi, Etsuko Ikoma, Shizuyo Honda, Masahiro Ishikawa, Yongmao Liu, Shinichi Kohsaka

Journal:

Year:

1998

Language:

english

File:

PDF, 692 KB

english, 1998

10

Ceramide-enhanced urokinase-type plasminogen activator (uPA) release is mediated by protein kinase C in cultured microglia

Kazuyuki Nakajima, Shizuyo Honda, Yoko Tohyama, Tadashi Kurihara, Shinichi Kohsaka

Journal:

Year:

2000

Language:

english

File:

PDF, 161 KB

english, 2000

11

22q13 microduplication in two patients with common clinical manifestations: A recognizable syndrome?

Nobuhiko Okamoto, Takeo Kubota, Yutaka Nakamura, Ryusuke Murakami, Toshiya Nishikubo, Ichiro Tanaka, Yukihiro Takahashi, Shin Hayashi, Issei Imoto, Johji Inazawa, Noboru Hosokai, Shinichi Kohsaka, Shi

Journal:

American Journal of Medical Genetics Part A

Year:

2007

Language:

english

File:

PDF, 204 KB

english, 2007

12

Microglia and the early phase of immune surveillance in the axotomized facial motor nucleus: Impaired microglial activation and lymphocyte recruitment but no effect on neuronal survival or axonal regeneration in macrophage-colony stimulating factor-deficient mice

Roger Kalla, Zhiqiang Liu, Shengli Xu, Andrea Koppius, Yoshinori Imai, Christian U.A. Kloss, Shinichi Kohsaka, Andreas Gschwendtner, J. Carsten Möller, Alexander Werner, Gennadij Raivich

Journal:

The Journal of Comparative Neurology

Year:

2001

Language:

english

File:

PDF, 2.99 MB

english, 2001

13

Intracellular signaling in M-CSF-induced microglia activation: Role of Iba1

Yoshinori Imai, Shinichi Kohsaka

Journal:

Year:

2002

Language:

english

File:

PDF, 1.16 MB

english, 2002

14

Editorial

Uwe-Karsten Hanisch, Shinichi Kohsaka, Thomas Möller

Journal:

Year:

2002

Language:

english

File:

PDF, 41 KB

english, 2002

15

Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis

Keiko Ohsawa, Yasuhiro Irino, Yasuko Nakamura, Chihiro Akazawa, Kazuhide Inoue, Shinichi Kohsaka

Journal:

Year:

2007

Language:

english

File:

PDF, 1.00 MB

english, 2007

16

Reduced synaptic activity precedes synaptic stripping in vagal motoneurons after axotomy

Jun Yamada, Yoshinori Hayashi, Shozo Jinno, Zhou Wu, Kazuhide Inoue, Shinichi Kohsaka, Hiroshi Nakanishi

Journal:

Year:

2008

Language:

english

File:

PDF, 874 KB

english, 2008

17

The Alzheimer's disease drug memantine increases the number of radial glia-like progenitor cells in adult hippocampus

Takashi Namba, Motoko Maekawa, Shigeki Yuasa, Shinichi Kohsaka, Shigeo Uchino

Journal:

Year:

2009

Language:

english

File:

PDF, 456 KB

english, 2009

18

P2Y12 receptor-mediated integrin-β1 activation regulates microglial process extension induced by ATP

Keiko Ohsawa, Yasuhiro Irino, Tomomi Sanagi, Yasuko Nakamura, Eri Suzuki, Kazuhide Inoue, Shinichi Kohsaka

Journal:

Year:

2010

Language:

english

File:

PDF, 802 KB

english, 2010

19

Dynamic motility of microglia: Purinergic modulation of microglial movement in the normal and pathological brain

Keiko Ohsawa, Shinichi Kohsaka

Journal:

Year:

2011

Language:

english

File:

PDF, 584 KB

english, 2011

20

Role of cell cycle-associated proteins in microglial proliferation in the axotomized rat facial nucleus

Shinichi Yamamoto, Shinichi Kohsaka, Kazuyuki Nakajima

Journal:

Year:

2012

Language:

english

File:

PDF, 2.08 MB

english, 2012

21

Inhibition of NMDA receptors induces delayed neuronal maturation and sustained proliferation of progenitor cells during neocortical development

Takae Hirasawa, Hidenori Wada, Shinichi Kohsaka, Shigeo Uchino

Journal:

Journal of Neuroscience Research

Year:

2003

Language:

english

File:

PDF, 1.93 MB

english, 2003

22

Neurotrophin secretion from cultured microglia

Kazuyuki Nakajima, Shizuyo Honda, Yoko Tohyama, Yoshinori Imai, Shinichi Kohsaka, Tadashi Kurihara

Journal:

Journal of Neuroscience Research

Year:

2001

Language:

english

File:

PDF, 253 KB

english, 2001

23

Microglial α7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role

Tomohisa Suzuki, Izumi Hide, Akiyo Matsubara, Chihiro Hama, Kana Harada, Kanako Miyano, Matthias Andrä, Hiroaki Matsubayashi, Norio Sakai, Shinichi Kohsaka, Kazuhide Inoue, Yoshihiro Nakata

Journal:

Journal of Neuroscience Research

Year:

2006

Language:

english

File:

PDF, 470 KB

english, 2006

24

In vitro proliferation of axotomized rat facial nucleus-derived activated microglia in an autocrine fashion

Kazuyuki Nakajima, Manuel B. Graeber, Maya Sonoda, Yoko Tohyama, Shinichi Kohsaka, Tadashi Kurihara

Journal:

Journal of Neuroscience Research

Year:

2006

Language:

english

File:

PDF, 1.27 MB

english, 2006

25

Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia

Yasuhiro Irino, Yasuko Nakamura, Kazuhide Inoue, Shinichi Kohsaka, Keiko Ohsawa

Journal:

Journal of Neuroscience Research

Year:

2008

Language:

english

File:

PDF, 549 KB

english, 2008

26

Activation of microglia by endotoxin suppresses the secretion of glial cell line–derived neurotrophic factor (GDNF) through the action of protein kinase Cα (PKCα) and mitogen-activated protein kinases (MAPKS)

Yuichi Matsushita, Kazuyuki Nakajima, Yoko Tohyama, Tadashi Kurihara, Shinichi Kohsaka

Journal:

Journal of Neuroscience Research

Year:

2008

Language:

english

File:

PDF, 460 KB

english, 2008

27

Appearance of phagocytic microglia adjacent to motoneurons in spinal cord tissue from a presymptomatic transgenic rat model of amyotrophic lateral sclerosis

Tomomi Sanagi, Shigeki Yuasa, Yasuko Nakamura, Eri Suzuki, Masashi Aoki, Hitoshi Warita, Yasuto Itoyama, Shigeo Uchino, Shinichi Kohsaka, Keiko Ohsawa

Journal:

Journal of Neuroscience Research

Year:

2010

Language:

english

File:

PDF, 969 KB

english, 2010

28

Microglial conditioned medium promotes survival and development of cultured mesencephalic neurons from embryonic rat brain

K. Nagata, N. Takei, K. Nakajima, H. Saito, Shinichi Kohsaka

Journal:

Journal of Neuroscience Research

Year:

1993

Language:

english

File:

PDF, 796 KB

english, 1993

29

Intact microglia are cultured and non-invasively harvested without pathological activation using a novel cultured cell recovery method

Kazuyuki Nakajima, Shizuyo Honda, Yasuko Nakamura, Fernando López-Redondo, Shinichi Kohsaka, Masayuki Yamato, Akihiko Kikuchi, Teruo Okano

Journal:

Year:

2001

Language:

english

File:

PDF, 485 KB

english, 2001

30

Synthesis of derivatives of (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC) modified at the 1-aromatic moiety as novel NMDA receptor antagonists: the aromatic group is essential for the activity

Yuji Kazuta, Ryuichi Tsujita, Kanako Yamashita, Shigeo Uchino, Shinichi Kohsaka, Akira Matsuda, Satoshi Shuto

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 415 KB

english, 2002

31

Ceramide activates microglia to enhance the production/secretion of brain-derived neurotrophic factor (BDNF) without induction of deleterious factors in vitro

Kazuyuki Nakajima, Yoko Tohyama, Shinichi Kohsaka, Tadashi Kurihara

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 271 KB

english, 2002

32

Amino-terminal region of secreted form of amyloid precursor protein stimulates proliferation of neural stem cells

Ikuroh Ohsawa, Chizuko Takamura, Takako Morimoto, Mariko Ishiguro, Shinichi Kohsaka

Journal:

European Journal of Neuroscience

Year:

1999

Language:

english

File:

PDF, 401 KB

english, 1999

33

Real-time, two-dimensional visualization of ischaemia-induced glutamate release from hippocampal slices

Shigeo Uchino, Takeshi Nakamura, Kyoko Nakamura, Sadayo Nakajima-Iijima, Masayoshi Mishina, Shinichi Kohsaka, Yoshihisa Kudo

Journal:

European Journal of Neuroscience

Year:

2001

Language:

english

File:

PDF, 593 KB

english, 2001

34

Plasminogen Binds Specifically to α-Enolase on Rat Neuronal Plasma Membrane

Kazuyuki Nakajima, Makoto Hamanoue, Nagisa Takemoto, Tatsuya Hattori, Kanefusa Kato, Shinichi Kohsaka

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 1.35 MB

english, 1994

35

Induction of Urokinase-Type Plasminogen Activator in Rat Facial Nucleus by Axotomy of the Facial Nerve

Kazuyuki Nakajima, Martin Reddington, Shinichi Kohsaka, Georg W. Kreutzberg

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 1.06 MB

english, 1996

36

Molecular Cloning and Characterization of Annexin V-Binding Proteins with Highly Hydrophilic Peptide Structure

Keiko Ohsawa, Yoshinori Imai, Daisuke Ito, Shinichi Kohsaka

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 1.01 MB

english, 1996

37

Induction of Ganglioside Biosynthesis and Neurite Outgrowth of Primary Cultured Neurons by l-threo-1-Phenyl-2-Decanoylamino-3-Morpholino-1-Propanol

Seigou Usuki, Makoto Hamanoue, Shinichi Kohsaka, Jin-ichi Inokuchi

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 1.20 MB

english, 1996

38

Selective Activation of Phospholipase Cγ1 and Distinct Protein Kinase C Subspecies in Intracellular Signaling by Hepatocyte Growth Factor/Scatter Factor in Primary Cultured Rat Neocortical Cells

Mitsuru Machide, Kazuyo Kamitori, Yasuko Nakamura, Shinichi Kohsaka

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 1.49 MB

english, 1998

39

Extracellular ATP Triggers Tumor Necrosis Factor-α Release from Rat Microglia

Izumi Hide, Masaya Tanaka, Atsuko Inoue, Kazuyuki Nakajima, Shinichi Kohsaka, Kazuhide Inoue, Yoshihiro Nakata

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 635 KB

english, 2000

40

Fibulin-1 binds the amino-terminal head of β-amyloid precursor protein and modulates its physiological function

Ikuroh Ohsawa, Chizuko Takamura, Shinichi Kohsaka

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 588 KB

english, 2001

41

Mechanisms underlying extracellular ATP-evoked interleukin-6 release in mouse microglial cell line, MG-5

Yukari Shigemoto-Mogami, Schuichi Koizumi, Makoto Tsuda, Keiko Ohsawa, Shinichi Kohsaka, Kazuhide Inoue

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 649 KB

english, 2001

42

Long-term changes of spine dynamics and microglia after transient peripheral immune response triggered by LPSin vivo

Satoru Kondo, Shinichi Kohsaka, Shigeo Okabe

Journal:

Molecular Brain

Year:

2011

Language:

english

File:

PDF, 8.17 MB

english, 2011

43

Effects of glycoprotein synthesis inhibitor on myelination in rat cerebellum

Shinichi Kohsaka, Koichi Mita, Haruhiko Suda, Masayuki Matsuyama, Yasuzo Tsukada

Journal:

Neurochemical Research

Year:

1985

Language:

english

File:

PDF, 1.21 MB

english, 1985

44

Disorders in myelination in thetwitchermutant: Immunohistochemical and biochemical studies

Katsuhiko Mikoshiba, Masatoshi Fujishiro, Shinichi Kohsaka, Hideyuki Okano, Ken Takamatsu, Yasuzo Tsukada

Journal:

Neurochemical Research

Year:

1985

Language:

english

File:

PDF, 1.75 MB

english, 1985

45

Association of osteopontin with ischemic axonal death in periventricular leukomalacia

Fumi Tanaka, Yuri Ozawa, Yukiko Inage, Kimiko Deguchi, Masayuki Itoh, Yoshinori Imai, Shinichi Kohsaka, Sachio Takashima

Journal:

Acta Neuropathologica

Year:

2000

Language:

english

File:

PDF, 271 KB

english, 2000

46

High expression of MeCP2 in JC virus-infected cells of progressive multifocal leukoencephalopathy brains

Saya Shirai, Kenta Takahashi, Shinji Kohsaka, Tetsu Tsukamoto, Hiroshi Isogai, Shinichi Kudo, Hirofumi Sawa, Kazuo Nagashima, Shinya Tanaka

Journal:

Year:

2011

Language:

english

File:

PDF, 284 KB

english, 2011

47

Cerebellar Hypoplasia in the Gunn Rat with Hereditary Hyperbilirubinemia: Immunohistochemical and Neurochemical Studies

Katsuhiko Mikoshiba, Shinichi Kohsaka, Ken Takamatsu, Yasuzo Tsukada

Journal:

Journal of Neurochemistry

Year:

1980

Language:

english

File:

PDF, 1.21 MB

english, 1980

48

Morphological and Biochemical Studies on the Cerebral Cortex from Reeler Mutant Mice: Development of Cortical Layers and Metabolic Mapping by the Deoxyglucose Method

Katsuhiko Mikoshiba, Shinichi Kohsaka, Ken Takamatsu, Emiko Aoki, Yasuzo Tsukada

Journal:

Journal of Neurochemistry

Year:

1980

Language:

english

File:

PDF, 1.15 MB

english, 1980

49

Uridine Metabolism in the Goldfish Retina During Optic Nerve Regeneration: Whole Retina Studies

Linda A. Dokas, Shinichi Kohsaka, Harry R. Burrell, Bernard W. Agranoff

Journal:

Journal of Neurochemistry

Year:

1981

Language:

english

File:

PDF, 536 KB

english, 1981

50

Uridine Metabolism in the Goldfish Retina During Optic Nerve Regeneration: Cell-Free Preparations

Shinichi Kohsaka, Linda A. Dokas, Bernard W. Agranoff

Journal:

Journal of Neurochemistry

Year:

1981

Language:

english

File:

PDF, 782 KB

english, 1981