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51

HPLC-API/MS/MS: a powerful tool for integrating drug metabolism into the drug discovery process

Walter A Korfmacher, Kathleen A Cox, Matthew S Bryant, John Veals, Kwokei Ng, Chin-chung Lin, Robert Watkins

Journal:

Drug Discovery Today

Year:

1997

Language:

english

File:

PDF, 712 KB

english, 1997

52

Novel in vivo procedure for rapid pharmacokinetic screening of discovery compounds in rats

Kathleen A. Cox, Kimberly Dunn-Meynell, Walter A. Korfmacher, Lisa Broske, Amin A. Nomeir, Chin-Chung Lin, Mitchell N. Cayen, William H. Barr

Journal:

Drug Discovery Today

Year:

1999

Language:

english

File:

PDF, 200 KB

english, 1999

53

Rapid in vivo oral screening in rats: Reliability, acceptance criteria, and filtering efficiency

Hong Mei, Walter Korfmacher, Richard Morrison

Journal:

The AAPS Journal

Year:

2006

Language:

english

File:

PDF, 383 KB

english, 2006

54

Analysis of 2,3,7,8-tetrachlorodibenzofuran by fused silica GC combined with atmospheric pressure ionization MS

Walter A. Korfmacher, Ronald K. Mitchum, Fred D. Hileman, Thomas Mazer

Journal:

Year:

1983

Language:

english

File:

PDF, 266 KB

english, 1983

55

Analysis of snake tissue and snake eggs for 2,3,7,8-tetrachlorodibenzo-p-dioxin via fused silica GC combined with atmospheric pressure ionization MS

Walter A. Korfmacher, Kenneth R. Rowland, Ronald K. Mitchum, James J. Daly, Robert C. McDaniel, Michael V. Plummer

Journal:

Year:

1984

Language:

english

File:

PDF, 204 KB

english, 1984

56

Tissue distribution of 2,3,7,8-TCDD in bullfrogs obtained from a 2,3,7,8-TCDD-contaminated area

Walter A. Korfmacher, Eugene B. Hansen Jr., Kenneth L. Rowland

Journal:

Year:

1986

Language:

english

File:

PDF, 259 KB

english, 1986

57

Use of bullfrogs (Rana catesbeiana) as biological markers for 2,3,7,8-tetrachlorodibenzo-p-dioxin contamination in the environment

Walter A. Korfmacher, Eugene B. Hansen Jr., Kenneth L. Rowland

Journal:

Science of The Total Environment

Year:

1986

Language:

english

File:

PDF, 319 KB

english, 1986

58

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Overview of the Various Types of Mass Spectrometers that are Used in Drug Discovery and Drug Development

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 1.14 MB

english, 2013

59

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Quantitative Mass Spectrometry Considerations in a Regulated Environment

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 1.63 MB

english, 2013

60

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Mass Spectrometry for Quantitative In Vitro ADME Assays

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 791 KB

english, 2013

61

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Utility of High-Resolution Mass Spectrometry for New Drug Discovery Applications

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 693 KB

english, 2013

62

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Metabolite Identification Using Mass Spectrometry in Drug Development

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 893 KB

english, 2013

63

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || MS Analysis of Biological Drugs, Proteins, and Peptides

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 1.93 MB

english, 2013

64

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Liquid Extraction Surface Analysis (LESA): A New Mass Spectrometry-Based Technique for Ambient Surface Profiling

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 1.39 MB

english, 2013

65

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Characterization of Impurities and Degradation Products in Small Molecule Pharmaceuticals and Biologics

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

66

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Imaging Mass Spectrometry for Drugs and Metabolites

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 4.75 MB

english, 2013

67

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || MS Applications in Support of Medicinal Chemistry Sciences

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 1.47 MB

english, 2013

68

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Screening Reactive Metabolites: Role of Liquid Chromatography-High-Resolution Mass Spectrometry in Combination with “Intelligent” Data Mining Tools

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 506 KB

english, 2013

69

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Imaging Mass Spectrometry of Proteins and Peptides

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 3.57 MB

english, 2013

70

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Mass Spectrometry of siRNA

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

71

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Mass Spectrometry for Metabolomics

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 742 KB

english, 2013

72

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Quantitative Analysis of Peptides with Mass Spectrometry: Selected Reaction Monitoring or High-Resolution Full Scan?

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 747 KB

english, 2013

73

High-resolution mass spectrometry will dramatically change our drug-discovery bioanalysis procedures

Korfmacher, Walter

Journal:

Year:

2011

Language:

english

File:

PDF, 348 KB

english, 2011

74

Preface to the 2013 Special Focus Issue of Bioanalysis on high-resolution MS

Korfmacher, Walter, Ramanathan, Ragu

Journal:

Year:

2013

Language:

english

File:

PDF, 908 KB

english, 2013

75

Rapid LC/MS/MS Method Development for Drug Discovery

Xu, Xiaoying, Lan, Jing, Korfmacher, Walter A.

Journal:

Analytical Chemistry

Year:

2005

Language:

english

File:

PDF, 422 KB

english, 2005

76

Fungal transformations of antihistamines : metabolism of cyproheptadine hydrochloride by Cunninghamella elegans

ZHANG, DONGLU, HANSEN, EUGENE B., DECK, JOANNA, HEINZE, THOMAS M., HENDERSON, ALLISON, KORFMACHER, WALTER A., CERNIGLIA, CARL E.

Journal:

Year:

1997

Language:

english

File:

PDF, 356 KB

english, 1997

77

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Frontmatter

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 234 KB

english, 2013

78

Mass Spectrometry for Drug Discovery and Drug Development (Korfmacher/Mass Spectrometry for Drug Discovery and Drug Development) || Wiley Series on Mass Spectrometry

Korfmacher, Walter A.

Year:

2013

Language:

english

File:

PDF, 196 KB

english, 2013

79

Direct Plasma Analysis of Drug Compounds Using Monolithic Column Liquid Chromatography and Tandem Mass Spectrometry

Hsieh, Yunsheng, Wang, Ganfeng, Wang, Yuguang, Chackalamannil, Samuel, Korfmacher, Walter A.

Journal:

Analytical Chemistry

Year:

2003

Language:

english

File:

PDF, 122 KB

english, 2003

80

High-Performance Liquid Chromatography-Atmospheric Pressure Photoionization/Tandem Mass Spectrometric Analysis for Small Molecules in Plasma

Hsieh, Yunsheng, Merkle, Kara, Wang, Ganfeng, Brisson, Jean-Marc, Korfmacher, Walter A.

Journal:

Analytical Chemistry

Year:

2003

Language:

english

File:

PDF, 115 KB

english, 2003

81

Comparison of Atmospheric Pressure Chemical Ionization, Electrospray Ionization, and Atmospheric Pressure Photoionization for the Determination of Cyclosporin A in Rat Plasma

Wang, Ganfeng, Hsieh, Yunsheng, Korfmacher, Walter A.

Journal:

Analytical Chemistry

Year:

2005

Language:

english

File:

PDF, 133 KB

english, 2005

82

Assessment of the contamination of a multibuilding facility by polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins, and polychlorinated dibenzofurans

Thompson, Harold C., Kendall, Donald C., Korfmacher, Walter A., Rowland, Kenneth L., Rushing, Larry G., Chen, James J., Kominsky, John R., Smith, Larry M., Stalling, David L.

Journal:

Environmental Science & Technology

Year:

1986

Language:

english

File:

PDF, 1.80 MB

english, 1986

83

Nonphotochemical decomposition of fluorene vapor-adsorbed on coal fly ash

Korfmacher, Walter A., Mamantov, Gleb., Wehry, Earl L., Natusch, David F. S., Mauney, Thad.

Journal:

Environmental Science & Technology

Year:

1981

Language:

english

File:

PDF, 739 KB

english, 1981

84

Molecular determinants of the platelet aggregation inhibitory activity of carbamoylpiperidines

Feng, Zixia, Gollamudi, Ramachander, Dillingham, Elwood O., Bond, Stephen E., Lyman, Beverly A., Purcell, William P., Hill, Robert J., Korfmacher, Walter A.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.76 MB

english, 1992

85

Atmospheric Pressure Ionization Mass Spectrometry

Mitchum, Ronald K., Korfmacher, Walter A.

Journal:

Analytical Chemistry

Year:

1983

Language:

english

File:

PDF, 9.01 MB

english, 1983

86

Supercritical Fluid Chromatography−Tandem Mass Spectrometry for the Enantioselective Determination of Propranolol and Pindolol in Mouse Blood by Serial Sampling

Chen, Jiwen, Hsieh, Yunsheng, Cook, John, Morrison, Richard, Korfmacher, Walter A.

Journal:

Analytical Chemistry

Year:

2006

Language:

english

File:

PDF, 125 KB

english, 2006

87

Direct simultaneous analysis of plasma samples for a drug discovery compound and its hydroxyl metabolite using mixed-function column liquid chromatography-tandem mass spectrometry

Hsieh, Yunsheng, Brisson, Jean-Marc, Ng, Kwokei, White, Ronald E., Korfmacher, Walter A.

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2001

Language:

english

File:

PDF, 124 KB

english, 2001

88

[Progress in Pharmaceutical and Biomedical Analysis] Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS Volume 6 || Chapter 2 Strategies for increasing throughput for pk samples in a drug discovery environment

Korfmacher, Walter A.

Year:

2005

Language:

english

File:

PDF, 1.85 MB

english, 2005

89

The emergence of high-resolution MS as the premier analytical tool in the pharmaceutical bioanalysis arena

Ramanathan, Ragu, Korfmacher, Walter

Journal:

Year:

2012

Language:

english

File:

PDF, 886 KB

english, 2012

90

MALDI–tandem mass spectrometry imaging of astemizole and its primary metabolite in rat brain sections

Li, Fangbiao, Hsieh, Yunsheng, Kang, Ling, Sondey, Christopher, Lachowicz, Jean, Korfmacher, Walter A

Journal:

Year:

2009

Language:

english

File:

PDF, 1.35 MB

english, 2009

91

Fungal transformations of antihistamines: Metabolism of methapyrilene, thenyldiamine and tripelennamine to N-oxide and N-demethylated derivatives

Cerniglia, Carl E., Hansen, Eugene B., Lambert, Kenneth J., Korfmacher, Walter A., Miller, Dwight W.

Journal:

Year:

1988

Language:

english

File:

PDF, 705 KB

english, 1988

92

Fast Mass Spectrometry-Based Methodologies for Pharmaceutical Analyses

Hsieh, Yunsheng, Fukuda, Elaine, Wingate, Julie, Korfmacher, Walter

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2006

Language:

english

File:

PDF, 182 KB

english, 2006

93

Capillary microsampling of whole blood for mouse PK studies: an easy route to serial blood sampling

Korfmacher, Walter, Fitzgerald, Maria, Luo, Yongyi, Ho, Stacy, Wang, Jie, Wu, Zhongtao, Snow, Gregory, O'Shea, Thomas

Journal:

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

94

Increasing Speed and Throughput When Using HPLC-MS/MS Systems forDrug Metabolism and Pharmacokinetic Screening

Hsieh, Yunsheng, A. Korfmacher, Walter

Journal:

Current Drug Metabolism

Year:

2006

Language:

english

File:

PDF, 371 KB

english, 2006

95

Editorial [ Use of Mass Spectrometry for Drug Metabolism Studies (Guest Editor: Walter A. Korfmacher )]

A. Korfmacher, Walter

Journal:

Current Drug Metabolism

Year:

2006

Language:

english

File:

PDF, 14 KB

english, 2006

96

DNA adduct formation in target tissues of Sprague-Dawley rats, CD-1 mice and A/J mice following tumorigenic doses of 1-nitropyrene

Smith, Beverly A., Korfmacher, Walter A., Beland, Frederick A.

Journal:

Year:

1990

Language:

english

File:

PDF, 5.07 MB

english, 1990

97

Utility of capillary microsampling for rat pharmacokinetic studies: Comparison of tail-vein bleed to jugular vein cannula sampling

Korfmacher, Walter, Luo, Yongyi, Ho, Stacy, Sun, Wei, Shen, Liduo, Wang, Jie, Wu, Zhongtao, Guo, Yang, Snow, Gregory, O'Shea, Thomas

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2015

Language:

english

File:

PDF, 1.66 MB

english, 2015

98

Evaluation of two blood microsampling approaches for drug discovery PK studies in rats

Luo, Yongyi, Korfmacher, Walter, Ho, Stacy, Shen, Liduo, Wang, Jie, Wu, Zhongtao, Guo, Yang, Snow, Gregory, O'Shea, Thomas

Journal:

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

99

Visualization of First-Pass Drug Metabolism of Terfenadine by MALDIImaging Mass Spectrometry

Hsieh, Yunsheng, Chen, Jiwen, Knemeyer, Ian, Crossman, Lee, Korfmacher, Walter

Journal:

Drug Metabolism Letters

Year:

2008

Language:

english

File:

PDF, 169 KB

english, 2008

100

Pharmacokinetics of Pseudoephedrine in Rats, Dogs, Monkeys and Its Pharmacokinetic-Pharmacodynamic Relationship in a Feline Model of Nasal Congestion

R. Palamanda, Jairam, Mei, Hong, Morrison, Richard, L. McLeod, Robbie, McCormick, Kevin, Corboz, Michel, Xu, Xiaoying, Korfmacher, Walter, Broske, Lisa, A. Nomeir, Amin

Journal:

Drug Metabolism Letters

Year:

2010

Language:

english

File:

PDF, 205 KB

english, 2010