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51

The behavior of 1,4-benzodiazepine drugs in acidic media. VI. Hydrogen exchange reaction and proton and carbon-13 nuclear magnetic resonance spectra of estazolam.

KUWAYAMA, TOMONARI, YASHIRO, TAMOTSU, KURONO, YUKIHISA, IKEDA, KEN

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 530 KB

1986

52

The behavior of 1,4-benzodiazepine drugs in acidic media. V. Kinetics of hydrolysis of flutazolam and haloxazolam in aqueous solution.

KUWAYAMA, TOMONARI, KURONO, YUKIHISA, MURAMATSU, TSUYUKO, YASHIRO, TAMOTSU, IKEDA, KEN

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 724 KB

1986

53

Photo-stabilization and solubilization of an aldose reductase inhibitor, (E)-3-carboxymethyl-5-((2E)-methyl-3-phenylpropenylidene)rhodanine (ONO-2235), by human serum albumin.

KURONO, YUKIHISA, FURUKAWA, AKIHIRO, TAKESUE, YOKO, LI, FENGLONG, IKEDA, KEN

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 421 KB

english, 1987

54

Kinetics and mechanism of the acid-base equilibrium of mexazolam and comparison with those of other commercial benzodiazepinooxazole drugs.

KURONO, YUKIHISA, KAMIYA, KINYA, KUWAYAMA, TOMONARI, JINNO, YASUHIRO, YASHIRO, TAMOTSU, IKEDA, KEN

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 890 KB

english, 1987

55

Effects of drug bindings on the esterase-like activity of human serum albumin. VII. Subdivision of R-type drugs inhibiting the activity towards p-nitrophenyl acetate.

KURONO, YUKIHISA, OZEKI, YOSHIRO, YAMADA, HIDETO, TAKEUCHI, TOSHIMASA, IKEDA, KEN

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 837 KB

english, 1987

56

Kinetics and mechanism of reversible hydrolysis of 11b-methylbenzodiazepinooxazoles.

KURONO, YUKIHISA, JINNO, YASUHIRO, KUWAYAMA, TOMONARI, YASHIRO, TAMOTSU, IKEDA, KEN

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1988

File:

PDF, 538 KB

1988

57

Kinetics and mechanism of the acid-base equilibrium of benzodiazepinooxazoles (oxazolam analogs).

KURONO, YUKIHISA, KUWAYAMA, TOMONARI, JINNO, YASUHIRO, KAMIYA, KINYA, YAMADA, ETSUKO, YASHIRO, TAMOTSU, IKEDA, KEN

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1988

File:

PDF, 785 KB

1988

58

Esterase-like activity of human serum albumin. VI. Reaction with p-nitrophenyl glycinate.

KURONO, YUKIHISA, FURUKAWA, AKIHIRO, TSUJI, TAKESHI, IKEDA, KEN

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1988

Language:

english

File:

PDF, 951 KB

english, 1988

59

cis/trans Isomerization rate of oxazolam in organic solvents measured by high-performance liquid chromatography.

KURONO, Yukihisa, JINNO, Yasuhiro, KUWAYAMA, Tomonari, SATO, Naomi, YASHIRO, Tamotsu, IKEDA, Ken

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1989

File:

PDF, 522 KB

1989

60

The behavior of 1,4-benzodiazepine drugs in acidic media. Part XIV. Kinetics and mechanism of the acid-base equilibrium and the subsequent hydrolysis of 11b-hydrogenbenzodiazepinooxazoles.

KURONO, Yukihisa, SAWABE, Hiroshi, KUWAYAMA, Tomonari, YASHIRO, Tamotsu, IKEDA, Ken

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1990

File:

PDF, 544 KB

1990

61

The crystal and molecular structure of racemic 11b-methylbenzodiazepinooxazole.

HATANO, Keiichiro, KURONO, Yukihisa, KUWAYAMA, Tomonari, MURAKAMI, Akimitsu, YASHIRO, Tamotsu, IKEDA, Ken

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1990

File:

PDF, 487 KB

1990

62

Reissert-type reaction of N-sulfonyl- or N-acyl-phthalazinium salts with trimethyl phosphite and crystal structure of dimethyl 2-mesyl-1,2-dihydro-1-phthalazinylphosphonate.

TAKEUCHI, Isao, HAMADA, Yoshiki, HATANO, Keiichiro, KURONO, Yukihisa, YASHIRO, Tamotsu

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1990

File:

PDF, 460 KB

1990

63

Esterase-like Activity of Human Serum Albumin. VII. Reaction with p-Nitrophenyl 4-Guanidinobenzoate.

KURONO, Yukihisa, MIYAJIMA, Makoto, TSUJI, Takeshi, YANO, Taishi, TAKEUCHI, Toshimasa, IKEDA, Ken

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1991

File:

PDF, 534 KB

1991

64

The Behavior of 1,4-Benzodiazepine Drugs in Acidic Media, Part XVII. Kinetics and Mechanism of the Acid-Base Equilibrium and the Hydrolysis of Benzodiazepinooxazines.

KURONO, Yukihisa, TANI, hidetoshi, KUWAYAMA, Tomonari, Hatano, Keiichiro, YASHIRO, Tamotsu, IKEDA, Ken

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1991

File:

PDF, 619 KB

1991

65

Esterase-Like Activity of Human Serum Albumin. VIII. Reaction with Amino Acid p-Nitrophenyl Esters.

KURONO, Yukihisa, KUSHIDA, Ikuo, TANAKA, Hikaru, IKEDA, Ken

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1992

File:

PDF, 603 KB

1992

66

The Study of Nitrogen-Containing Heterocyclic Compounds. Part XI. Regiospecific Nitration of Quinoline and Isoquinoline throuth the Reissert Compounds.

SUGIURA, Michiharu, HATNO, Keiichiro, HIRAO, Kimihiko, MOGI, Kouichi, KURONO, Yukihisa, YASHIRO, Tamotsu, USAMI, Takeshi, HAMADA, Yoshiki

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1992

File:

PDF, 697 KB

1992

67

Kinetics and Mechanism of Tautomerism of a Hydroxy Schiff Base, N-[2-{2-Hydroxyethylimino(methyl)methyl}phenyl]-2-chlorpropamide, in Solution.

KURONO, Yukihisa, TAMAKI, Hiroshi, YOKOTA, Yasunari, IDA, Mitsuyasu, SUGIMOTO, Chiaki, KUWAYAMA, Tomonari, IKEDA, Ken, YASHIRO, Tamotsu

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1994

File:

PDF, 665 KB

1994

68

Stereochemical Aspects during Substitution Reaction Reaction of c-4-Bromo-r-1-cyano-c-3-methoxy-1,2,3,4-tetrahydroisoquinoline Derivatives with Amines.

SUGIURA, Michiharu, ASAI, Koosuke, HAMADA, Yoshiki, HATANO, Keiichiro, KURONO, Yukihisa, SUEZAWA, Hiroko, HIROTA, Minoru

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1997

File:

PDF, 632 KB

1997

69

Stereochemistry of c-4-Bromo-r-1-cyano-t-3-methoxy-1,2,3,4-tetrahydroisoquinolines from Isoquinoline Reissert Compounds.

SUGIURA, Michiharu, ASAI, Koosuke, HAMADA, Yoshiki, HATANO, Keiichiro, KURONO, Yukihisa, SUEZAWA, Hiroko, HIROTA, Minoru

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1997

File:

PDF, 558 KB

1997

70

Cooperation among Pharmaceutical, Medical and Nursing Schools Aimed at 6-year Pharmaceutical Education

Ono, Hideki, Kurono, Yukihisa

Journal:

YAKUGAKU ZASSHI

Year:

2012

File:

PDF, 725 KB

2012

71

Effect of ortho-substituents on methanesulfonic acid derivative of substituted aniline.

KURONO, YUKIHISA, IKEDA, KEN, UEKAMA, KANETO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1975

File:

PDF, 619 KB

1975

72

Esterase-like activity of human serum albumin. V. Reaction with 2,4-dinitrophenyl diethyl phosphate.

YOSHIDA, KOHSUKE, KURONO, YUKIHISA, MORI, YOSHIKO, IKEDA, KEN

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1985

File:

PDF, 679 KB

1985

73

Release rates of substituted aniline from its methanesulfonic acid derivative in acid region.

KURONO, YUKIHISA, IKEDA, KEN, UEKAMA, KANETO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1975

File:

PDF, 695 KB

1975

74

Effects of drug binding on the esterase-like activity of human serum albumin. III. Evaluation of reactivities of the two active sites by using clofibric acid as an inhibitor.

KURONO, YUKIHISA, OHTA, NAOKO, YOTSUYANAGI, TOSHIHISA, IKEDA, KEN

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1981

File:

PDF, 610 KB

1981

75

Methanesulfonic acid derivative of N-alkyl aniline: Basicity of aniline and reactivity.

KURONO, YUKIHISA, IKEDA, KEN, YAMAMURA, FUMIKO, YOTSUYANAGI, TOSHIHISA

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1976

File:

PDF, 527 KB

1976

76

Synthesis and Stereochemistry of 3,7-Diazatricyclo[4.2.2.22,5]dodeca-9,11-dienes Derived by [4+4] Cyclodimerization of 2,3-Dihydroisoquinoline Derivatives.

SUGIURA, Michiharu, ASAI, Koosuke, HAMADA, Yoshiki, HATANO, Keiichiro, KURONO, Yukihisa, SUEZAWA, Hiroko, HIROTA, Minoru

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1998

File:

PDF, 643 KB

1998

77

Acylcarnitine Profiles during Carnitine Loading and Fasting Tests in a Japanese Patient with Medium-Chain Acyl-CoA Dehydrogenase Deficiency

Yokoi, Kyoko, Ito, Tetsuya, Maeda, Yasuhiro, Nakajima, Yoko, Ueta, Akihito, Nomura, Takayasu, Koyama, Norihisa, Kato, Ineko, Suzuki, Satoshi, Kurono, Yukihisa, Sugiyama, Naruji, Togari, Hajime

Journal:

The Tohoku Journal of Experimental Medicine

Year:

2007

Language:

english

File:

PDF, 290 KB

english, 2007

78

Detection of Pivaloylcarnitine in Pediatric Patients with Hypocarnitinemia after Long-Term Administration of Pivalate-Containing Antibiotics

Nakajima, Yoko, Ito, Tetsuya, Maeda, Yasuhiro, Ichiki, Sayaka, Sugiyama, Naruji, Mizuno, Mihoko, Makino, Yasuko, Sugiura, Tokio, Kurono, Yukihisa, Togari, Hajime

Journal:

The Tohoku Journal of Experimental Medicine

Year:

2010

Language:

english

File:

PDF, 480 KB

english, 2010

79

The Behavior of 1, 4-Benzodiazepine Drugs in Acidic Media. XV. Contribution of Iminium Structure to the Proton Exchange Reaction of 11b-Methylbenzodiazepinooxazoles

KUWAYAMA, Tomonari, KURONO, Yukihisa, SAWABE, Hiroshi, KATO, Setsuko, YASHIRO, Tamotsu, IKEDA, Ken

Journal:

YAKUGAKU ZASSHI

Year:

1990

File:

PDF, 666 KB

1990

80

Interaction of Camptothecin Derivatives with Human Plasma Proteins in Vitro

KURONO, Yukihisa, MIYAJIMA, Makoto, IKEDA, Ken

Journal:

YAKUGAKU ZASSHI

Year:

1993

File:

PDF, 789 KB

1993

81

Interaction between Human Serum Albumin and Thromboxane A2Synthetase Inhibitors (OKY-1580 and OKY-046)

LI, FENGLONG, KURONO, YUKIHISA, FURUKAWA, AKIHIRO, IKEDA, KEN

Journal:

YAKUGAKU ZASSHI

Year:

1986

File:

PDF, 664 KB

1986

82

The Behavior of 1, 4-Benzodiazepine Drugs in Acidic Media. XVI. Estimation of cis/trans Isomer Ratio of Benzodiazepinooxazoles Using Nuclear Magnetic Resonance Shift Reagent

KUWAYAMA, Tomonari, KATO, Setsuko, KURONO, Yukihisa, HATANO, Keiichiro, HAYAZAKI, Takanori, YASHIRO, Tamotsu, IKEDA, Ken

Journal:

YAKUGAKU ZASSHI

Year:

1990

File:

PDF, 689 KB

1990

83

Enzymatic Activity and Drug Binding Activity of Human Serum Albumin

IKEDA, KEN, KURONO, YUKIHISA

Journal:

YAKUGAKU ZASSHI

Year:

1986

Language:

english

File:

PDF, 1.85 MB

english, 1986

84

The Behavior of 1, 4-Benzodiazepine Drugs in Acidic Media. XII. : Proton Exchange Reaction of 11b-Methylbenzodiazepinooxazoles

KUWAYAMA, TOMONARI, KATO, SETSUKO, KURONO, YUKIHISA, YASHIRO, TAMOTSU, IKEDA, KEN

Journal:

YAKUGAKU ZASSHI

Year:

1988

File:

PDF, 600 KB

1988

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